4th & Aspen Life Sciences Consulting helps biotech and pharmaceutical companies with drug discovery and development. They have decades of experience in target identification, preclinical research, and commercial assessment. Their team of scientific founders have track records of innovation and leadership at companies like DNAX, Genentech, Neuroscience Inc. 4th & Aspen offers services like opportunity assessment, preclinical evaluation, and commercialization support to help clients manage risk and increase the likelihood of success.

1. 4th & Aspen Life Sciences Consulting
Supercharging R&D innovation .

2. Our mission
© 2014 4th & Aspen LLC
We help companies in the
discovery and development
of innovative biotools &
biotherapeutics.
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3. Our Founders
B.S., PhD
Univ. of Minnesota, Minneapolis
Postdoctoral research
DNAX Research Institute
MBA
Presidio Graduate School
Senior Scientist
Abgenix, Inc.
Senior Scientist
Entelos, Inc.
VP, Marketing; VP, R&D
NeuroScience, Inc.
Scientific Review Officer
SRA International
© 2014 4th & Aspen LLC
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B.S. PhD
Stanford UC-Berkeley
Postdoctoral research
UCSF
Senior Scientist
DNAX Research Institute
Senior Scientist
Genentech (Roche)
Visiting Scientist
Stanford University
Chief Scientific Officer
NeuroScience Inc.
Chief Technical Officer
R&D Systems/Techne
Sirid Kellermann, President Fernando Bazan, Principal

4. Why work with 4th & Aspen?
© 2014 4th & Aspen LLC
Our key strengths:
✔ A deep understanding of how biological systems work
✔ A track record of elucidating novel target mechanisms -
repeatedly breaking new ground in drug discovery
(www.4thandaspen.com/our-expertise/cases)
✔ The ability to work across scientific fields and catalyze
interdisciplinary collaborations that are often lacking, but
critical to innovation
✔ Industry-proven decision analysis approach to guide target
selection and R&D portfolio strategies
✔ Experience in biopharma market research, competitive
analysis, & commercial assessment
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5. We bring 3 decades of leadership
in target discovery and preclinical R&D
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© 2014 4th & Aspen LLC
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6. We bring 3 decades of leadership
in target discovery and preclinical R&D
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Disease-associated
target discovery
Protein structure/
function
Cellular & in vivo
validation
R&D portfolio
evaluation
Biomarker evaluation
& clinical trial
optimization
Market &
commercial
assessmentProtein signaling/
relationships

7. Sirid Kellermann: Strategic project &
relationship management successes
© 2014 4th & Aspen LLC
• Strong expertise in immuno-
inflammatory disorders
• >20 R&D projects executed
with global biopharma clients
• R&D and Marketing leadership
• Training in strategic decision &
risk management
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8. 130 publications
>25,000 citations
>35 patents
Fernando Bazan: A track record
of scientific innovation
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© 2014 4th & Aspen LLC

9. Our Services Your Benefits
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Preclinical Evaluation
Nuanced insights on target disease
relevance; predicted effects of target
perturbation
Strategic recommendations for small
molecule or biotherapeutic design
In vitro/in vivo proof-of-concept
strategy recommendations
Opportunity Assessment
Integrate molecular/biological and
competitive/market frames
Recommend program prioritization to
manage risk and increase likelihood of
commercial success
Commercialization Support
Perform in-licensing scientific diligence
Guide investment/funding/spin-off
decisions
Support IP prosecution
Facilitate collaborations with
extensive industry & academic network
Marketing & Writing
White papers, scientific reviews, grant
applications
Presentations that get noticed
Content marketing (blogs, etc.)

10. © 2014 4th & Aspen LLC
Ready to supercharge your innovation engine?
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Info[at]4thandaspen.com www.4thandaspen.com 650.996.9927