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BENIGN PAROXYSMAL
POSITIONAL VERTIGO
Basic Anatomy
BPPV
Barany 1921
Dix-Hallpike 1952 – important features
of nystagmus
Abnormal sensation of motion elicited
by certain critical positions
Provocative position  nystagmus
At least 20% of vertigo
Underestimated
BPPV …
Subclassification : scc post/lat/ant/bilat
Pathophysiology :
–   Canalithiasis
–   cupulolithiasis
Pathophysiology
Pathophysiology (cont.)
Cupulolithiasis :
– Harold Schuknecht 1962
– Densities (otocania) adherent to cupula of
  crista ampullaris
– Basophilic particles -1969
Canalithiasis :
– John Epley – 1980
– Densities free floating in canal portion
– Parnes , McClure – 1991 found particles in
  post SCC
BPPV ...
Frequency : 10-64/100000
Sex : 64% women
Age : older population ( 51-57)
     younger than 35 – head trauma.
History :
–   sudden
–   days-weeks
–   occassionally months -years
–    episodes.
Physical :
– neurological examination – normal
– except – Dix-Hallpike  pathognomonic
BPPV …
Nystagmus : characterization and types
– RT / LT , vertical / horizontal , changing
– Tortional = Rotational – clockwise /
  counterclockwise
– Geotropic- toward the earth
– Ageotropic – opposite
BPPV …
Classic post SCC – geotropic rotatory
nystagmus
Horizontal SCC – purely horizontal
nystagmus
Non-fatiguing nystagmus –
cupulolithiasis > canalithiasis
Classic BPPV
Involved the POST SCC
– Geotropic NG with affected ear down
– Rotatory , fast phase toward the undermost
  ear
– Latency – few seconds
– Duration – limited < 20 seconds
– Reversal upon return upright position
– Response decline upon repetitive
  provocation
Lat. SCC PPV
Most common atypical BPPV
3-9% of cases
Consequence of Epley maneuver
Horizontal purely nystagmus
Cupulolithiasis rather than canalithiasis
Modified Epley / lampert maneuver …
Lat. SCC PPV
Ant. SCC PPV
Rare – 2%
Down-beating /torsional NG for the
opposite ear on Dix-Hallpike maneuver
BPPV - Causes
Predisposing factors :
–   Inactivity
–   Acute alcoholism
–   Major surgery
–   CNS disease
Causes ( cont. )
Idiopathic – 39%
Ear disease – 29%
–   OM – 9%
–   Vestibular neuritis – 7%
–   Menier’s dis – 7%
–   Otosclerosis – 4%
–   Sudden SNHL – 2%
Trauma – 21%
Causes ( cont. )
Trauma – 21%
CNS diseases – 11%
Acustic neuroma – 2%
Cervical vertigo – 2%
BPPV - D.D
Menier’s disease
Inner ear concussion
Alcohol intoxication
Labyrinthitis
Vascular loop syndrome
Post. Fossa lesions : acustic neuroma ,
meningioma
Central origion : stroke , MS , cerebellar
degeneration
Vertibral artery insuffeciency
Cervical vertigo
BPPV - Treatment
Watchful waiting
Vestibular suppressant medications
Vestibular rehabilitation
Canalith repositioning
Surgery care
–   Labyrinthectomy
–   Post. Canal occlusion
–   Singula neurectomy
–   Transtympanic aminpglycoside application
Trials about BPPV
General
Labeled benign paroxysmal positional
vertigo is not always benign
Evaluation of the effectiveness of
canalith reepositioning procedurs –
CRP
Several studies …
Trials …
Blakely – 1994 :
– 50% improvement in the control and CRP
  group !! ( 2-3 months)
Lynn – 1995 :
– Randomized-controlled : 89% negative DH
  in CRP group , 27% in the control group
John Li (1995) :
Trials…
John Li (1995) :
– Comparison CRP / CRP + mastoid oscillation and
  control
– Modified Epley maneuver
– Use of colar and head elevation after CRP
– No spontaneous resolution within aweek
– 60% symptoms improvement in CRP group
– 92% symptoms improvement in CRP +mastoid
  oscilation and 70% negative DH
Trials…
R. steenerson –1996 :
– Comparison of CRP and vestibular
  habituation training
– Tow approaches are effective in
  symptomatic relief ( 3 months)
– CRP faster relief and fewer treatments
Trials …
K. Yimatae (2003)
– Randomized-controoled
– Modified Epley maneuver, no mastoid oscillator
  and no instructions after the maneuver
– Subjective and objective weekly follow-up
– CRP group – 76% negative DH, 48% control group
– CRP group – 96% symptoms improvement , 90%
  control group
– Non-cured patients need > 6 procedures in 2
  weeks , should considering liberatory maneuver
Elderly population and BPPV
  S. Angeli – 2003 :
  – Effectiveness of CRP and VR
  – Modified Epley :
        Elderly comorbidities : degenerative osteoarthritis
        disease , CVA , peripheral neuropathy, cognitive and
        autonomic dysfunctions
        S/E of CRP – neck torsion and extension result in
        vertibrobasilar artery insufficiency, strain on the spine
        column, dislodged carotid a. emboli
        Avoid liberatory maneuver
  –   64% CRP group – negative DH after a month
  –   Overall 77% with CRP and VR
CRP Meta-Analysis
            B. Woodworth - 2004


CRP - First line of treatment
–   Non-invasive
–   Easy to perform in the office
–   No need to expensive instrumentations
–   Repeat maneuver if needed
–   Potential to provide rapid relief of vertigo
Meta - Analysis
9 randomized-controlled trials
Symptoms resolution and elimination of
positive Dix-Hallpike test
CRP more effective than control ( x5 )
Untreated patients - symptoms
improvements with time but positive DH
So Resolution of vertigo – avoidance of
provocative positions
CRP – Epley maneuver
CRP – Semont maneuver
Mastoid oscillator
Brandt-Daroff Exsercise
Lampert maneuver- Lat. SCC
          BPPV
Vestibular rehabilitaions
Complications of CRP
Failure – 25% (12%-56)
Recurrence – 13% in 6 months
Side effects
–   Nausea
–   Vomiting
–   Fainting
–   Sweating
Worse vertigo – LAT SCC PPV
THANK YOU …

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Benign paroxysmal positional vertigo

  • 3. BPPV Barany 1921 Dix-Hallpike 1952 – important features of nystagmus Abnormal sensation of motion elicited by certain critical positions Provocative position  nystagmus At least 20% of vertigo Underestimated
  • 4. BPPV … Subclassification : scc post/lat/ant/bilat Pathophysiology : – Canalithiasis – cupulolithiasis
  • 6. Pathophysiology (cont.) Cupulolithiasis : – Harold Schuknecht 1962 – Densities (otocania) adherent to cupula of crista ampullaris – Basophilic particles -1969
  • 7. Canalithiasis : – John Epley – 1980 – Densities free floating in canal portion – Parnes , McClure – 1991 found particles in post SCC
  • 8. BPPV ... Frequency : 10-64/100000 Sex : 64% women Age : older population ( 51-57) younger than 35 – head trauma. History : – sudden – days-weeks – occassionally months -years – episodes.
  • 9. Physical : – neurological examination – normal – except – Dix-Hallpike  pathognomonic
  • 10. BPPV … Nystagmus : characterization and types – RT / LT , vertical / horizontal , changing – Tortional = Rotational – clockwise / counterclockwise – Geotropic- toward the earth – Ageotropic – opposite
  • 11. BPPV … Classic post SCC – geotropic rotatory nystagmus Horizontal SCC – purely horizontal nystagmus Non-fatiguing nystagmus – cupulolithiasis > canalithiasis
  • 12. Classic BPPV Involved the POST SCC – Geotropic NG with affected ear down – Rotatory , fast phase toward the undermost ear – Latency – few seconds – Duration – limited < 20 seconds – Reversal upon return upright position – Response decline upon repetitive provocation
  • 13. Lat. SCC PPV Most common atypical BPPV 3-9% of cases Consequence of Epley maneuver Horizontal purely nystagmus Cupulolithiasis rather than canalithiasis Modified Epley / lampert maneuver …
  • 15. Ant. SCC PPV Rare – 2% Down-beating /torsional NG for the opposite ear on Dix-Hallpike maneuver
  • 16. BPPV - Causes Predisposing factors : – Inactivity – Acute alcoholism – Major surgery – CNS disease
  • 17. Causes ( cont. ) Idiopathic – 39% Ear disease – 29% – OM – 9% – Vestibular neuritis – 7% – Menier’s dis – 7% – Otosclerosis – 4% – Sudden SNHL – 2% Trauma – 21%
  • 18. Causes ( cont. ) Trauma – 21% CNS diseases – 11% Acustic neuroma – 2% Cervical vertigo – 2%
  • 19. BPPV - D.D Menier’s disease Inner ear concussion Alcohol intoxication Labyrinthitis Vascular loop syndrome Post. Fossa lesions : acustic neuroma , meningioma Central origion : stroke , MS , cerebellar degeneration Vertibral artery insuffeciency Cervical vertigo
  • 20. BPPV - Treatment Watchful waiting Vestibular suppressant medications Vestibular rehabilitation Canalith repositioning Surgery care – Labyrinthectomy – Post. Canal occlusion – Singula neurectomy – Transtympanic aminpglycoside application
  • 22. General Labeled benign paroxysmal positional vertigo is not always benign Evaluation of the effectiveness of canalith reepositioning procedurs – CRP Several studies …
  • 23. Trials … Blakely – 1994 : – 50% improvement in the control and CRP group !! ( 2-3 months) Lynn – 1995 : – Randomized-controlled : 89% negative DH in CRP group , 27% in the control group John Li (1995) :
  • 24. Trials… John Li (1995) : – Comparison CRP / CRP + mastoid oscillation and control – Modified Epley maneuver – Use of colar and head elevation after CRP – No spontaneous resolution within aweek – 60% symptoms improvement in CRP group – 92% symptoms improvement in CRP +mastoid oscilation and 70% negative DH
  • 25. Trials… R. steenerson –1996 : – Comparison of CRP and vestibular habituation training – Tow approaches are effective in symptomatic relief ( 3 months) – CRP faster relief and fewer treatments
  • 26. Trials … K. Yimatae (2003) – Randomized-controoled – Modified Epley maneuver, no mastoid oscillator and no instructions after the maneuver – Subjective and objective weekly follow-up – CRP group – 76% negative DH, 48% control group – CRP group – 96% symptoms improvement , 90% control group – Non-cured patients need > 6 procedures in 2 weeks , should considering liberatory maneuver
  • 27. Elderly population and BPPV S. Angeli – 2003 : – Effectiveness of CRP and VR – Modified Epley : Elderly comorbidities : degenerative osteoarthritis disease , CVA , peripheral neuropathy, cognitive and autonomic dysfunctions S/E of CRP – neck torsion and extension result in vertibrobasilar artery insufficiency, strain on the spine column, dislodged carotid a. emboli Avoid liberatory maneuver – 64% CRP group – negative DH after a month – Overall 77% with CRP and VR
  • 28. CRP Meta-Analysis B. Woodworth - 2004 CRP - First line of treatment – Non-invasive – Easy to perform in the office – No need to expensive instrumentations – Repeat maneuver if needed – Potential to provide rapid relief of vertigo
  • 29. Meta - Analysis 9 randomized-controlled trials Symptoms resolution and elimination of positive Dix-Hallpike test CRP more effective than control ( x5 ) Untreated patients - symptoms improvements with time but positive DH So Resolution of vertigo – avoidance of provocative positions
  • 30. CRP – Epley maneuver
  • 31. CRP – Semont maneuver
  • 36. Complications of CRP Failure – 25% (12%-56) Recurrence – 13% in 6 months Side effects – Nausea – Vomiting – Fainting – Sweating Worse vertigo – LAT SCC PPV