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Horizon 2020 proposal writing
Horizon 2020
experts
Ontwerp: Toldt / www.toldt.nl
Horizon 2020
experts
Horizon 2020 proposal writing
Horizon 2020: the EU
Framework Programme
for Research and
Innovation
Horizon 2020 is the European grant and sub-
sidy framework for innovation and R&D.The
programme, running from 2014 to 2020, has a
budget of €70 billion and aims to secure Eu-
rope’s global competitiveness. Horizon 2020
is built up of three pillars, Excellent Science,
Industrial leadership and Societal Challenge.
The Excellent Science pillar will raise the
level of excellence of Europe’s science base
in order to make it more competitive on a
global scale.
The Excellent Science pillar of Horizon 2020
is characterised by:
•	 Support of the most talented and
creative researchers and their teams to
carry out high-level frontier research.
•	 Funding of collaborative research in
new and promising fields.
•	 Providing excellent training and
career development opportunities
for researchers.
•	 Providing researchers with access to
world-class research infrastructure.
The Industrial Leadership pillar will
invest in key technologies, better access to
capital and support for Small and Medium
Enterprises (SMEs) in order to make Europe
a more attractive location to invest in
research and innovation.
The Industrial Leadership pillar focuses on:
•	 Developing European industrial
capabilities in so-called key enabling
technologies, including nanotechnology
and biotechnology.
•	 Facilitating access to risk finance by
leveraging private finance and venture
capital for research and innovation.
•	 Stimulating innovation in SMEs by
fostering all forms of innovation in all
types of SMEs.
The Societal Challenges pillar helps to
bridge the gap between research and the
market in order to tackle societal challenges.
This is done by dealing with concerns shared
What is Horizon 2020?
Horizon 2020 offers the perfect opportunity for academia and industry to finance
research and development activities. Excellent Science, Competitive Industries and
Tackling Societal Challenges are at the top of the strategic agenda.
4
ttopstart - Horizon 2020 proposal writing
by European citizens and reflects policy
priorities of the Europe 2020 strategy that
cannot be achieved without innovation.
Resources and knowledge across various
fields will be brought together, activities
from research to market will be covered
and promising solutions will be tested and
verified.
Horizon 2020:
key features
Six specific types of actions
Horizon 2020 consists of six different types
of actions (project types), each with their
own set of provisions and funding rates.
Collaborative research and innovation
projects are part of Research and Innovation
Actions (RIA); Innovation Actions (IA) and
the SME-instrument.
Simplified set of financial rules
The EU contribution is up to 100% of the
total eligible costs for RIA projects and up to
70% for IA projects. In all cases, indirect costs
will be covered by a flat rate of 25% of the
direct costs.
Increased participation of industry
including SMEs
Research and development within Public
Private Partnerships is promoted, e.g. through
increased participation of industry, including
SMEs.
Excellent
science
Industrial
leadership
Societal
challenges
∙ European Research Council
∙ Marie Sklodowska-Curie Actions
∙ Future and Emerging technologies
∙ Research infrastructures
∙	 Health, demographic change
	 and wellbeing
∙	 Inclusive, innovative and
	 secure societies
∙	 Leadership in enabling
	 and industrial technologies
∙	 Access to risk finance
∙	 Innovation in SMEs
5
At ttopstart, we combine science and business, specialising in the fields of
life sciences, healthcare and medical technology
ttopstart has been built on the unique combination of science and business,
with a focus on the life sciences, medical technology and healthcare sectors.
Our consultants have a solid scientific background combined with an extensive
business skill set.This is a key advantage for your Horizon 2020 application,
considering the increased EC demands for translation of research, public private
partnerships and societal impact. Proposals do not leave our office without
scientific and business excellence. In addition, our consultants provide you
with a bird's-eye view of your project plan; with their experience they can
pinpointing aspects in need for improvement to be able to compete in this
competitive arena.
ttopstart is able to write 80% of the total application
ttopstart can write the Horizon 2020 proposal (in close contact with the
consortium), allowing you to focus on the scientific work plan. ttopstart
manages the entire application process: from writing the body of the proposal,
to collecting, streamlining and merging partner input, setting up detailed
budget plans, distributing draft versions, handling partner feedback and final
submission.This allows you to spend most of your time on the scientific quality
and overall management.
Why ttopstart?
ttopstart is a European science and business consulting company
that is able to write 80% of your Horizon 2020 application and provides
professional management, dissemination and exploitation services.
ttopstart focuses on projects in the field of life sciences, healthcare and
medical technology.
6
ttopstart - Horizon 2020 proposal writing
ttopstart supports you with professional non-scientific management and
delivers high-quality dissemination and exploitation services for new and
existing Horizon 2020 projects
Professional scientific and non-scientific management is a prerequisite for
your Horizon 2020 consortium - and highly appreciated by reviewers. In
the application phase, we offer a large toolbox with proven management
frameworks and can tailor a model for project management and consortium
organisation. In the project phase, we are a strong consortium partner for
non-scientific management, dissemination and exploitation.This includes
monitoring and reporting of deliverables, organising meetings and drafting
progress reports. ttopstart specialises in developing creative and detailed
stakeholder-sensitive plans for dissemination and exploitation of project
outcomes, ensuring that stakeholders are involved, output is IP protected and
commercialised and impact is maximised. For more details, see our Project
Management, Dissemination and Exploitation brochure.
ttopstart facilitates strategic preparations for a head start in Horizon 2020
Is your organisation or department fully prepared to take the lead (or take part)
in Horizon 2020 projects? Are you confident that your projects will get funded?
Building on years of experience in the field of European subsidies, ttopstart can
rapidly analyse the competitiveness of your organisation in a subsidy context.
Moreover, we can give practical recommendations for optimal preparation for
success in Horizon 2020 - even prior to any application.Whilst not guaranteeing
success, a head start will definitely increase your chances.
7
IMI Project (University Utrecht/
Sanofi-Aventis)
Size: €30M
Topic: Drug delivery
An international consortium, coordinated by
Utrecht University and Sanofi Aventis, has
been awarded a European grant for studying
targeted delivery of biopharmaceuticals.
The total project size is €30 million.The
consortium consists of 16 academic institutes
and several pharmaceutical companies.The
project title is COMPACT - Collaboration to
Optimise Macromolecular Pharmaceutical
Access to Cellular Targets.
ttopstart supported University Utrecht and
Sanofi-Aventis with acquiring an IMI Grant for
biopharmaceutical delivery that resulted in
the COMPACT project.
PREPARE (University of Antwerp)
Size: €24M
Topic: Clinical management during
epidemics
PREPARE (Platform for European Preparedness
Against (Re-)emerging Epidemics) is an
EU-funded network for harmonised large-
scale clinical research studies on infectious
diseases, prepared to rapidly respond to
any severe ID outbreak, providing real-time
evidence for clinical management of patients
and for informing public health responses.
ttopstart successfully supported the PREPARE
consortium to acquire a €24M FP7 subsidy to
set up clinical research studies on infectious
diseases.
Key achievements
ttopstart has a sound track record in supporting academia and SMEs
with the preparation of winning subsidy proposals. Over the past years,
50% of our proposals submitted under Horizon2020 were granted.
In total, we have supported our clients in obtaining close to €250 million.
Some examples:
8
ttopstart - Horizon 2020 proposal writing
• 	 Horizon 2020: since it's implementation in 2014, ttopstart has supported
numerous multi-national research consortia in acquiring funding for their
innovative research projects (averaging ~€6M each) and ITNs (international
training networks).
• 	 ERC grants: ttopstart has a good track record in attracting ERC grants; we
have contributed to various approved ERC Starting Grants and ERC Advanced
Grants.We also have ample expertise with ECR Proof of Concept Grants:
18 out of 20 ERC PoC grants that we supported were funded.We not only
support researchers with the application for funding, but we are also active
in the granted project itself by providing our market intelligence and business
development services.
•	 Eurostars: ttopstart has managed over 13 successful Eurostars applications for
different SMEs throughout Europe. One of these applications was ranked as
#1 out of 306 applications.
FP7 ICT - VPH Project (Fraunhofer MEVIS)
Size: €6M
Topic: Personalised predictive breast cancer
FP7 HEALTH: BALANCE (AMC)
Size: €6M
Topic: Artificial Liver Device
Eurostars 2012 SeDi (Sohard)
Size: €1.2M
Topic: Medical software
FP7 ICT: SYMBITRON (Twente University)
Size: €3.5M
Topic: Health robotics
Horizon 2020 ITN-ETN: InCeM
(Universitätsklinikum Aachen)
Size: €3.9M
Topic: Medical imaging
ERC Advanced Grant
(VU University Medical Center)
Size: €2.5M
Topic: hrHPV screening
9
Our method
Fit
High-ranking projects show an ideal fit
between proposal and call text. Both
consortium and proposal must seamlessly
match with the EC's intentions. To optimise
this fit, ttopstart assists in:
•	 Finding strong consortium partners -
academic and industrial
•	 Critically assessing and strengthening
your initial project plan
“Through our experience and a devil's
advocate attitude we are able to rapidly
see whether a proposal idea has winning
potential.”
“Our approach is acknowledged for its
efficiency and harmony in the consortium.”
Framework
Uniting the visions of 5 - 30 partners into
a synchronised and solid proposal is one
of the main challenges for constructing a
winning bid. ttopstart offers the tools to
design a conceptual framework in which
the consortium's plans can be integrated
and fine-tuned towards a logical work plan.
We use the problem analysis and Pyramid
Principle in Horizon 2020 style in which we:
•	 Analyse the major problem – focal
problem – sub challenges
•	 Define the ultimate goal – project
objective – sub objectives
•	 Connect work packages and impact to
these items
ttopstart has developed the FFWD model to fast-forward you from
an innovative vision to a winning Horizon 2020 proposal. We
are highly motivated to succeed due to our risk-bearing strategy.
We specialise in impact, for the consortium and for society.
10
ttopstart - Horizon 2020 proposal writing
Write
Developing a convincing proposal
requires excellent writing skills, which are
represented in the ttopstart team. ttopstart
ensures a persuasive presentation of the
proposal by applying the 8 C's: conform,
complete, consistent, concise, concrete,
convincing, coherent and creative. ttopstart
guards timeliness and coordinates the
entire application process - which can be
as demanding as the writing part.
Development
Commercialisation, impact, dissemination
and exploitation are now a central part
of all Horizon 2020 proposals. ttopstart
excels at these sections because of our
extensive business consulting expertise.
ttopstart offers detailed market intelligence
and business development strategies to
leverage societal and economic impact.
During the application phase and the
course of the project, ttopstart is your
management and impact partner. We offer
a variety of (tailored) packages to facilitate
productive management, exploitation and
dissemination.
“The consortium is asked to deliver the
work packages in a draft format. With your
scientific input, ttopstart can set up the
entire proposal from beginning to end."
“Combining scientific and business expertise
in your project results in high impact
publications and valuable innovations."
Submission
Review EC
Negotiation
Knowledge utilisation
Project management
Development
Consortium
formation
Fit
Conceptualisation
of research plan
Framework
Proposal
preparation
Write
11
ttopstart's full service support for Horizon 2020 applications
With ttopstart's full service support we aim to take as much work out of your
hands as possible. Our experienced consultants will take the lead in the writing
and coordination throughout the process, while closely guarding the time to
deadline and quality of the proposal.They will gather all necessary input from
the consortium partners and combine this into a strong proposal.
ttopstart's basic service support for Horizon 2020 applications
In addition to our full service support, we also offer a basic support service.The
basic support service serves clients who want to stay in the lead of the process
themselves. Our consultants will support you during the application, providing
valuable input on quality and helping with the budget and consortium
formation.Textual input will be limited to the optimisation of selected parts.
ttopstart can support the complete application process for
a Horizon 2020 proposal. We offer writing capacity and experience,
a clear and concise presentation of the project
proposal and coordination of the entire application procedure.
Full application support
12
ttopstart - Horizon 2020 proposal writing
General info proposal
Summary
Administrative details participants
Budget per partner
Overall budget
Section 1: Exellence
	 Objectives
	 Relation to work programme
	 Concept and approach
	 Ambition
Section 3: Implementation
	 Work plan
	 Management structures
	 Consortium as a whole
	 Resources to be committed
Section 4: Consortium partners
Section 5: Ethics and Security
Section 2: Impact
	 Objectives
	 Relation to work programme
ttopstartClient
Full application support: ttopstart can write 80% of your Horizon 2020 proposal.
Part B
Part A
13
Submission
ttopstart’s review service follows our successful
FFWD method (see page 10) to assess your
proposal’s strengths and weaknesses. During
three iterations, an experienced consultant will
provide clear feedback, with easy-to-implement
tips and tricks to elevate your proposal to the
next level.
Fit and Framework
ttopstart will cross-check your proposal and
consortium against all eligibility rules and the
fit to the call text of the corresponding funding
scheme.We will assess the innovativeness
of the project plan and the coherence of the
framework.
Write
With access to over 100 subsidy applications,
ttopstart will provide you with‘best practices’
to present and highlight the strengths of
your project plan in an appealing manner.
We provide input on how to write a proposal
that can convince experts, while remaining
interesting and accessible for everyone. Our
consultants have excellent writing skills,
and will also provide a review on syntax and
spelling.
Development
In the third iteration, ttopstart will focus on the
persuasive and broad presentation of impact
and dissemination of the project results.We
will help you to couple these to key market
trends and policies. ttopstart can provide clear-
cut examples of how to write a convincing
implementation plan that spans beyond the
project.
Review service
F&F W D
·	 Fit the call
· 	Consortium build-up
· 	Innovativeness
· 	Coherent project 	plan
· 	Persuasive and
	 accessible
· 	SMART goals
· 	Management structure
· 	Broad impact
· 	Implementation plan
Building on our experience in writing winning subsidy proposals,
ttopstart is the ideal partner to extensively review your proposal.
We will provide you with a clear and easy-to-implement evaluation
which will improve your chances of success.
14
ttopstart - Horizon 2020 proposal writing
Training
Grant writing is like professional sports: in order to become and
remain successful it is necessary to improve continuously – especially
in an environment where public funding is under increasing pressure.
ttopstart has supported hundreds of applications for national and
international subsidy programmes and has shown a stable success
rate that exceeds the a priori chance at least 3-4 times. In our training
courses, we share our formula for success and help you understand
what is needed to write a competitive proposal.
ttopstart's outstanding success rate is, amongst other factors, attributable to
following a structured approach; our own FFWD model (Fit-Framework-Write-
Develop). By following this model, we take time to build a strong project plan,
the foundation for a strong proposal, before we start writing.Throughout the
process, we keep the reviewer close in mind, ensuring that the proposed work is
ambitious but not overselling, and that impact is always a central theme.
We now offer a novel training concept that can help you to implement these key
success criteria. In a tailored, in-house training programme, you will experience:
•	 How to apply key writing skills
•	 How to shape the central topic of your proposal
•	 How to organise the preparation of your proposal
•	 How to think like a reviewer
•	 How to centralise impact
All of our trainings are highly interactive and hands-on, meaning that actual
applications under preparation by the participants will be used as case studies
during the training.Where necessary, our training programmes can
be organised around specific subsidy calls.
ttopstart offers training in:
•	 Grant writing
•	 Horizon 2020 project management
•	 Networking for public-private partnerships
15
Excellent Science
The Marie Sklodowska-Curie Actions
Marie Sklodowska-Curie Actions focus on training and career development of
researchers.The actions provide grants at all stages of researchers' careers, and
encourage mobility across nations, sectors and disciplines.The following actions
are included:
•	 Innovative Training Networks (ITN) to train a new generation of creative,
	 entrepreneurial and innovative early stage researchers.There are three types
	 of ITNs:
•• ITN-ETN: European Training Networks (ETNs) produce highly-skilled
researchers and stimulate entrepreneurship, creativity and innovation
in Europe.
•• ITN-EID: European Industrial Doctorates (EIDs) meet the objectives of ITN
by involving the non-academic sector in doctoral training.
•• ITN-EJD: European Joint Doctorates (EJDs) promote international,
intersectoral and multi/interdisciplinary collaboration, leading to the delivery
of joint, double or multiple doctoral degrees.
•	 Individual Fellowships (IF) for experienced researchers wishing to diversify
their individual competence.
•	 Co-funding of regional, national and international programmes (COFUND)
to stimulate regional, national or international programmes to foster excellence
in researchers' training, mobility and career development.
•	 Research and Innovation Staff Exchange (RISE) for short term staff exchange
of universities, research centres or companies.
ttopstart is able to provide support with the writing and coordination of all
proposals relevant for academia and industry in life sciences, medical technology
and healthcare. This concerns topics from the following Work Programmes: ERC;
the Marie Sklodowska -Curie Actions; Leadership in Enabling and Industrial
Technologies; Health, Demographic Change and Wellbeing and Eurostars.
H2020 Work Programmes
16
ttopstart - Horizon 2020 proposal writing
European Research Council (ERC)
ERC Grants are individual grants aimed to encourage the highest quality research
in Europe through competitive funding, on the basis of scientific excellence.They
support investigator-initiated frontier research across all fields of research. Based
on the stage of their scientific career, researchers can apply for an ERC Starting,
Consolidator or Advanced Grant.The ERC Proof of Concept Grant is intended
for ERC grant holders to bridge the gap between research and earliest stage of
marketable innovation.
Industrial Leadership
Leadership in enabling and industrial technologies (LEIT)
LEIT focuses on new opportunities for industrial leadership in Europe.
Within LEIT, two Work Programmes are relevant for Health and Life Sciences:
‘Information and communication technologies’(ICT) and‘Nanotechnologies,
Advanced Materials, Biotechnology and Advanced Manufacturing and
Processing’(NMBP).
Information and Communication Technologies (LEIT-ICT) contains topics on
information management, robotics and micro-and nanoelectronic technologies
that are of interest for stakeholders in life sciences, medical technology and
healthcare.
Nanotechnologies, Advanced Materials, Biotechnology and Advanced
Manufacturing and Processing (LEIT-NMBP) will contribute to a technological
basis for nanomedicines and bio-materials by bringing it towards pilot
production as precondition for subsequent clinical trials.The biotechnology
projects aim to develop generic technological building blocks, enabling true
stepping stones towards solutions for – amongst others – better health.
Societal Challenge
Health, Demographic Change and Wellbeing
This Work Prgramme includes topics on personalised medicine that aim to fund
real breakthrough research and radical innovation in response to challenges
such as the ageing population and the increasing communicable and non-
communicable disease burden.
17
The Work Programmes LEIT and Health, Demographic Change and Wellbeing
consists of the following types of projects:
•	 Research and innovation actions: research projects aimed to establish new
knowledge and/or explore the feasibility of a new technology, product,
process etc.This includes basic and applied research and small-scale
technology development in a laboratory or simulated environment.
•	 Innovation actions: projects that focus on plans, arrangements or designs
for new, altered or improved products, processes or services.These include
demos, pilots, large-scale product validations and market replications.
•	 SME instrument: this instrument aims to fill gaps in funding for early-
stage, high-risk research and innovation by SMEs as well as stimulating
breakthrough innovations. It targets highly innovative SMEs showing a
strong ambition to develop, grow and internationalise, regardless of whether
they are high-tech and research-driven or non-research conducting, social
or service companies;
•	 Coordination and support action: project where supporting activities are
central;
•	 ERA-NET: a collaborative project between member states.
Other
Eurostars
Research intensive SMEs can acquire funding through Eurostars 2, the follow-
up of the successful Eurostars programme. Eurostars aims to support R&D
performing SMEs by co-financing market oriented innovation with a bottom-up
approach.With streamlined and improved procedures, Eurostars 2 will promote
technological and business development, while boosting employment as well as
exports for European small businesses.
If you are interested to learn more about certain Horizon 2020 topics, please
contact one of our consultants. For an up-to-date overview of all upcoming calls
and funding opportunities, visit our website www.ttopstart.com and subscribe
to our monthly newsletter.
18
ttopstart - Horizon 2020 proposal writing
The database is updated weekly with the latest funding opportunities. For each
funding option all relevant aspects are listed, as well as a link to the detailed call
text.The database can easily be searched and navigated and provides you with a
customised overview of relevant funding opportunities.
ttopstart's funding database has received international acclaim and has proven
to be a valuable tool for our clients.With many daily visitors, ttopstart provides
excellent support, advice and service to those seeking funding.
Your benefits:
•	 Overview of relevant EU and US funding programmes
•	 Free access
•	 Easy-to-use search engine
•	 Direct links to websites and specific factsheets
•	 Quick contact links to our specialised advisors
Comprehensive life science
funding database
ttopstart's online funding database gives your organisation an up-
to-date and comprehensive overview of the most relevant subsidies,
loans and fiscal stimulation programmes for your research and
development projects, in real-time and free.
19
Contact us
For more information please contact one of our consultants
or visit our website at www.ttopstart.com
Marije aan den Toorn, PhD - consultant
marije@ttopstart.com
Patrick de Boer MSc. - partner
patrick@ttopstart.com
+316 5389 7487
ir Jasper Levink - partner
jasper@ttopstart.com
+316 3434 2333
Jochem Bossenbroek MSc. - partner
jochem@ttopstart.com
+316 2244 2641
20
ttopstart - Horizon 2020 proposal writing
www.ttopstart.com

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Horizon 2020 brochure ttopstart - the horizon 2020 experts

  • 1. Horizon 2020 proposal writing Horizon 2020 experts
  • 2. Ontwerp: Toldt / www.toldt.nl
  • 4. Horizon 2020: the EU Framework Programme for Research and Innovation Horizon 2020 is the European grant and sub- sidy framework for innovation and R&D.The programme, running from 2014 to 2020, has a budget of €70 billion and aims to secure Eu- rope’s global competitiveness. Horizon 2020 is built up of three pillars, Excellent Science, Industrial leadership and Societal Challenge. The Excellent Science pillar will raise the level of excellence of Europe’s science base in order to make it more competitive on a global scale. The Excellent Science pillar of Horizon 2020 is characterised by: • Support of the most talented and creative researchers and their teams to carry out high-level frontier research. • Funding of collaborative research in new and promising fields. • Providing excellent training and career development opportunities for researchers. • Providing researchers with access to world-class research infrastructure. The Industrial Leadership pillar will invest in key technologies, better access to capital and support for Small and Medium Enterprises (SMEs) in order to make Europe a more attractive location to invest in research and innovation. The Industrial Leadership pillar focuses on: • Developing European industrial capabilities in so-called key enabling technologies, including nanotechnology and biotechnology. • Facilitating access to risk finance by leveraging private finance and venture capital for research and innovation. • Stimulating innovation in SMEs by fostering all forms of innovation in all types of SMEs. The Societal Challenges pillar helps to bridge the gap between research and the market in order to tackle societal challenges. This is done by dealing with concerns shared What is Horizon 2020? Horizon 2020 offers the perfect opportunity for academia and industry to finance research and development activities. Excellent Science, Competitive Industries and Tackling Societal Challenges are at the top of the strategic agenda. 4 ttopstart - Horizon 2020 proposal writing
  • 5. by European citizens and reflects policy priorities of the Europe 2020 strategy that cannot be achieved without innovation. Resources and knowledge across various fields will be brought together, activities from research to market will be covered and promising solutions will be tested and verified. Horizon 2020: key features Six specific types of actions Horizon 2020 consists of six different types of actions (project types), each with their own set of provisions and funding rates. Collaborative research and innovation projects are part of Research and Innovation Actions (RIA); Innovation Actions (IA) and the SME-instrument. Simplified set of financial rules The EU contribution is up to 100% of the total eligible costs for RIA projects and up to 70% for IA projects. In all cases, indirect costs will be covered by a flat rate of 25% of the direct costs. Increased participation of industry including SMEs Research and development within Public Private Partnerships is promoted, e.g. through increased participation of industry, including SMEs. Excellent science Industrial leadership Societal challenges ∙ European Research Council ∙ Marie Sklodowska-Curie Actions ∙ Future and Emerging technologies ∙ Research infrastructures ∙ Health, demographic change and wellbeing ∙ Inclusive, innovative and secure societies ∙ Leadership in enabling and industrial technologies ∙ Access to risk finance ∙ Innovation in SMEs 5
  • 6. At ttopstart, we combine science and business, specialising in the fields of life sciences, healthcare and medical technology ttopstart has been built on the unique combination of science and business, with a focus on the life sciences, medical technology and healthcare sectors. Our consultants have a solid scientific background combined with an extensive business skill set.This is a key advantage for your Horizon 2020 application, considering the increased EC demands for translation of research, public private partnerships and societal impact. Proposals do not leave our office without scientific and business excellence. In addition, our consultants provide you with a bird's-eye view of your project plan; with their experience they can pinpointing aspects in need for improvement to be able to compete in this competitive arena. ttopstart is able to write 80% of the total application ttopstart can write the Horizon 2020 proposal (in close contact with the consortium), allowing you to focus on the scientific work plan. ttopstart manages the entire application process: from writing the body of the proposal, to collecting, streamlining and merging partner input, setting up detailed budget plans, distributing draft versions, handling partner feedback and final submission.This allows you to spend most of your time on the scientific quality and overall management. Why ttopstart? ttopstart is a European science and business consulting company that is able to write 80% of your Horizon 2020 application and provides professional management, dissemination and exploitation services. ttopstart focuses on projects in the field of life sciences, healthcare and medical technology. 6 ttopstart - Horizon 2020 proposal writing
  • 7. ttopstart supports you with professional non-scientific management and delivers high-quality dissemination and exploitation services for new and existing Horizon 2020 projects Professional scientific and non-scientific management is a prerequisite for your Horizon 2020 consortium - and highly appreciated by reviewers. In the application phase, we offer a large toolbox with proven management frameworks and can tailor a model for project management and consortium organisation. In the project phase, we are a strong consortium partner for non-scientific management, dissemination and exploitation.This includes monitoring and reporting of deliverables, organising meetings and drafting progress reports. ttopstart specialises in developing creative and detailed stakeholder-sensitive plans for dissemination and exploitation of project outcomes, ensuring that stakeholders are involved, output is IP protected and commercialised and impact is maximised. For more details, see our Project Management, Dissemination and Exploitation brochure. ttopstart facilitates strategic preparations for a head start in Horizon 2020 Is your organisation or department fully prepared to take the lead (or take part) in Horizon 2020 projects? Are you confident that your projects will get funded? Building on years of experience in the field of European subsidies, ttopstart can rapidly analyse the competitiveness of your organisation in a subsidy context. Moreover, we can give practical recommendations for optimal preparation for success in Horizon 2020 - even prior to any application.Whilst not guaranteeing success, a head start will definitely increase your chances. 7
  • 8. IMI Project (University Utrecht/ Sanofi-Aventis) Size: €30M Topic: Drug delivery An international consortium, coordinated by Utrecht University and Sanofi Aventis, has been awarded a European grant for studying targeted delivery of biopharmaceuticals. The total project size is €30 million.The consortium consists of 16 academic institutes and several pharmaceutical companies.The project title is COMPACT - Collaboration to Optimise Macromolecular Pharmaceutical Access to Cellular Targets. ttopstart supported University Utrecht and Sanofi-Aventis with acquiring an IMI Grant for biopharmaceutical delivery that resulted in the COMPACT project. PREPARE (University of Antwerp) Size: €24M Topic: Clinical management during epidemics PREPARE (Platform for European Preparedness Against (Re-)emerging Epidemics) is an EU-funded network for harmonised large- scale clinical research studies on infectious diseases, prepared to rapidly respond to any severe ID outbreak, providing real-time evidence for clinical management of patients and for informing public health responses. ttopstart successfully supported the PREPARE consortium to acquire a €24M FP7 subsidy to set up clinical research studies on infectious diseases. Key achievements ttopstart has a sound track record in supporting academia and SMEs with the preparation of winning subsidy proposals. Over the past years, 50% of our proposals submitted under Horizon2020 were granted. In total, we have supported our clients in obtaining close to €250 million. Some examples: 8 ttopstart - Horizon 2020 proposal writing
  • 9. • Horizon 2020: since it's implementation in 2014, ttopstart has supported numerous multi-national research consortia in acquiring funding for their innovative research projects (averaging ~€6M each) and ITNs (international training networks). • ERC grants: ttopstart has a good track record in attracting ERC grants; we have contributed to various approved ERC Starting Grants and ERC Advanced Grants.We also have ample expertise with ECR Proof of Concept Grants: 18 out of 20 ERC PoC grants that we supported were funded.We not only support researchers with the application for funding, but we are also active in the granted project itself by providing our market intelligence and business development services. • Eurostars: ttopstart has managed over 13 successful Eurostars applications for different SMEs throughout Europe. One of these applications was ranked as #1 out of 306 applications. FP7 ICT - VPH Project (Fraunhofer MEVIS) Size: €6M Topic: Personalised predictive breast cancer FP7 HEALTH: BALANCE (AMC) Size: €6M Topic: Artificial Liver Device Eurostars 2012 SeDi (Sohard) Size: €1.2M Topic: Medical software FP7 ICT: SYMBITRON (Twente University) Size: €3.5M Topic: Health robotics Horizon 2020 ITN-ETN: InCeM (Universitätsklinikum Aachen) Size: €3.9M Topic: Medical imaging ERC Advanced Grant (VU University Medical Center) Size: €2.5M Topic: hrHPV screening 9
  • 10. Our method Fit High-ranking projects show an ideal fit between proposal and call text. Both consortium and proposal must seamlessly match with the EC's intentions. To optimise this fit, ttopstart assists in: • Finding strong consortium partners - academic and industrial • Critically assessing and strengthening your initial project plan “Through our experience and a devil's advocate attitude we are able to rapidly see whether a proposal idea has winning potential.” “Our approach is acknowledged for its efficiency and harmony in the consortium.” Framework Uniting the visions of 5 - 30 partners into a synchronised and solid proposal is one of the main challenges for constructing a winning bid. ttopstart offers the tools to design a conceptual framework in which the consortium's plans can be integrated and fine-tuned towards a logical work plan. We use the problem analysis and Pyramid Principle in Horizon 2020 style in which we: • Analyse the major problem – focal problem – sub challenges • Define the ultimate goal – project objective – sub objectives • Connect work packages and impact to these items ttopstart has developed the FFWD model to fast-forward you from an innovative vision to a winning Horizon 2020 proposal. We are highly motivated to succeed due to our risk-bearing strategy. We specialise in impact, for the consortium and for society. 10 ttopstart - Horizon 2020 proposal writing
  • 11. Write Developing a convincing proposal requires excellent writing skills, which are represented in the ttopstart team. ttopstart ensures a persuasive presentation of the proposal by applying the 8 C's: conform, complete, consistent, concise, concrete, convincing, coherent and creative. ttopstart guards timeliness and coordinates the entire application process - which can be as demanding as the writing part. Development Commercialisation, impact, dissemination and exploitation are now a central part of all Horizon 2020 proposals. ttopstart excels at these sections because of our extensive business consulting expertise. ttopstart offers detailed market intelligence and business development strategies to leverage societal and economic impact. During the application phase and the course of the project, ttopstart is your management and impact partner. We offer a variety of (tailored) packages to facilitate productive management, exploitation and dissemination. “The consortium is asked to deliver the work packages in a draft format. With your scientific input, ttopstart can set up the entire proposal from beginning to end." “Combining scientific and business expertise in your project results in high impact publications and valuable innovations." Submission Review EC Negotiation Knowledge utilisation Project management Development Consortium formation Fit Conceptualisation of research plan Framework Proposal preparation Write 11
  • 12. ttopstart's full service support for Horizon 2020 applications With ttopstart's full service support we aim to take as much work out of your hands as possible. Our experienced consultants will take the lead in the writing and coordination throughout the process, while closely guarding the time to deadline and quality of the proposal.They will gather all necessary input from the consortium partners and combine this into a strong proposal. ttopstart's basic service support for Horizon 2020 applications In addition to our full service support, we also offer a basic support service.The basic support service serves clients who want to stay in the lead of the process themselves. Our consultants will support you during the application, providing valuable input on quality and helping with the budget and consortium formation.Textual input will be limited to the optimisation of selected parts. ttopstart can support the complete application process for a Horizon 2020 proposal. We offer writing capacity and experience, a clear and concise presentation of the project proposal and coordination of the entire application procedure. Full application support 12 ttopstart - Horizon 2020 proposal writing
  • 13. General info proposal Summary Administrative details participants Budget per partner Overall budget Section 1: Exellence Objectives Relation to work programme Concept and approach Ambition Section 3: Implementation Work plan Management structures Consortium as a whole Resources to be committed Section 4: Consortium partners Section 5: Ethics and Security Section 2: Impact Objectives Relation to work programme ttopstartClient Full application support: ttopstart can write 80% of your Horizon 2020 proposal. Part B Part A 13
  • 14. Submission ttopstart’s review service follows our successful FFWD method (see page 10) to assess your proposal’s strengths and weaknesses. During three iterations, an experienced consultant will provide clear feedback, with easy-to-implement tips and tricks to elevate your proposal to the next level. Fit and Framework ttopstart will cross-check your proposal and consortium against all eligibility rules and the fit to the call text of the corresponding funding scheme.We will assess the innovativeness of the project plan and the coherence of the framework. Write With access to over 100 subsidy applications, ttopstart will provide you with‘best practices’ to present and highlight the strengths of your project plan in an appealing manner. We provide input on how to write a proposal that can convince experts, while remaining interesting and accessible for everyone. Our consultants have excellent writing skills, and will also provide a review on syntax and spelling. Development In the third iteration, ttopstart will focus on the persuasive and broad presentation of impact and dissemination of the project results.We will help you to couple these to key market trends and policies. ttopstart can provide clear- cut examples of how to write a convincing implementation plan that spans beyond the project. Review service F&F W D · Fit the call · Consortium build-up · Innovativeness · Coherent project plan · Persuasive and accessible · SMART goals · Management structure · Broad impact · Implementation plan Building on our experience in writing winning subsidy proposals, ttopstart is the ideal partner to extensively review your proposal. We will provide you with a clear and easy-to-implement evaluation which will improve your chances of success. 14 ttopstart - Horizon 2020 proposal writing
  • 15. Training Grant writing is like professional sports: in order to become and remain successful it is necessary to improve continuously – especially in an environment where public funding is under increasing pressure. ttopstart has supported hundreds of applications for national and international subsidy programmes and has shown a stable success rate that exceeds the a priori chance at least 3-4 times. In our training courses, we share our formula for success and help you understand what is needed to write a competitive proposal. ttopstart's outstanding success rate is, amongst other factors, attributable to following a structured approach; our own FFWD model (Fit-Framework-Write- Develop). By following this model, we take time to build a strong project plan, the foundation for a strong proposal, before we start writing.Throughout the process, we keep the reviewer close in mind, ensuring that the proposed work is ambitious but not overselling, and that impact is always a central theme. We now offer a novel training concept that can help you to implement these key success criteria. In a tailored, in-house training programme, you will experience: • How to apply key writing skills • How to shape the central topic of your proposal • How to organise the preparation of your proposal • How to think like a reviewer • How to centralise impact All of our trainings are highly interactive and hands-on, meaning that actual applications under preparation by the participants will be used as case studies during the training.Where necessary, our training programmes can be organised around specific subsidy calls. ttopstart offers training in: • Grant writing • Horizon 2020 project management • Networking for public-private partnerships 15
  • 16. Excellent Science The Marie Sklodowska-Curie Actions Marie Sklodowska-Curie Actions focus on training and career development of researchers.The actions provide grants at all stages of researchers' careers, and encourage mobility across nations, sectors and disciplines.The following actions are included: • Innovative Training Networks (ITN) to train a new generation of creative, entrepreneurial and innovative early stage researchers.There are three types of ITNs: •• ITN-ETN: European Training Networks (ETNs) produce highly-skilled researchers and stimulate entrepreneurship, creativity and innovation in Europe. •• ITN-EID: European Industrial Doctorates (EIDs) meet the objectives of ITN by involving the non-academic sector in doctoral training. •• ITN-EJD: European Joint Doctorates (EJDs) promote international, intersectoral and multi/interdisciplinary collaboration, leading to the delivery of joint, double or multiple doctoral degrees. • Individual Fellowships (IF) for experienced researchers wishing to diversify their individual competence. • Co-funding of regional, national and international programmes (COFUND) to stimulate regional, national or international programmes to foster excellence in researchers' training, mobility and career development. • Research and Innovation Staff Exchange (RISE) for short term staff exchange of universities, research centres or companies. ttopstart is able to provide support with the writing and coordination of all proposals relevant for academia and industry in life sciences, medical technology and healthcare. This concerns topics from the following Work Programmes: ERC; the Marie Sklodowska -Curie Actions; Leadership in Enabling and Industrial Technologies; Health, Demographic Change and Wellbeing and Eurostars. H2020 Work Programmes 16 ttopstart - Horizon 2020 proposal writing
  • 17. European Research Council (ERC) ERC Grants are individual grants aimed to encourage the highest quality research in Europe through competitive funding, on the basis of scientific excellence.They support investigator-initiated frontier research across all fields of research. Based on the stage of their scientific career, researchers can apply for an ERC Starting, Consolidator or Advanced Grant.The ERC Proof of Concept Grant is intended for ERC grant holders to bridge the gap between research and earliest stage of marketable innovation. Industrial Leadership Leadership in enabling and industrial technologies (LEIT) LEIT focuses on new opportunities for industrial leadership in Europe. Within LEIT, two Work Programmes are relevant for Health and Life Sciences: ‘Information and communication technologies’(ICT) and‘Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and Processing’(NMBP). Information and Communication Technologies (LEIT-ICT) contains topics on information management, robotics and micro-and nanoelectronic technologies that are of interest for stakeholders in life sciences, medical technology and healthcare. Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and Processing (LEIT-NMBP) will contribute to a technological basis for nanomedicines and bio-materials by bringing it towards pilot production as precondition for subsequent clinical trials.The biotechnology projects aim to develop generic technological building blocks, enabling true stepping stones towards solutions for – amongst others – better health. Societal Challenge Health, Demographic Change and Wellbeing This Work Prgramme includes topics on personalised medicine that aim to fund real breakthrough research and radical innovation in response to challenges such as the ageing population and the increasing communicable and non- communicable disease burden. 17
  • 18. The Work Programmes LEIT and Health, Demographic Change and Wellbeing consists of the following types of projects: • Research and innovation actions: research projects aimed to establish new knowledge and/or explore the feasibility of a new technology, product, process etc.This includes basic and applied research and small-scale technology development in a laboratory or simulated environment. • Innovation actions: projects that focus on plans, arrangements or designs for new, altered or improved products, processes or services.These include demos, pilots, large-scale product validations and market replications. • SME instrument: this instrument aims to fill gaps in funding for early- stage, high-risk research and innovation by SMEs as well as stimulating breakthrough innovations. It targets highly innovative SMEs showing a strong ambition to develop, grow and internationalise, regardless of whether they are high-tech and research-driven or non-research conducting, social or service companies; • Coordination and support action: project where supporting activities are central; • ERA-NET: a collaborative project between member states. Other Eurostars Research intensive SMEs can acquire funding through Eurostars 2, the follow- up of the successful Eurostars programme. Eurostars aims to support R&D performing SMEs by co-financing market oriented innovation with a bottom-up approach.With streamlined and improved procedures, Eurostars 2 will promote technological and business development, while boosting employment as well as exports for European small businesses. If you are interested to learn more about certain Horizon 2020 topics, please contact one of our consultants. For an up-to-date overview of all upcoming calls and funding opportunities, visit our website www.ttopstart.com and subscribe to our monthly newsletter. 18 ttopstart - Horizon 2020 proposal writing
  • 19. The database is updated weekly with the latest funding opportunities. For each funding option all relevant aspects are listed, as well as a link to the detailed call text.The database can easily be searched and navigated and provides you with a customised overview of relevant funding opportunities. ttopstart's funding database has received international acclaim and has proven to be a valuable tool for our clients.With many daily visitors, ttopstart provides excellent support, advice and service to those seeking funding. Your benefits: • Overview of relevant EU and US funding programmes • Free access • Easy-to-use search engine • Direct links to websites and specific factsheets • Quick contact links to our specialised advisors Comprehensive life science funding database ttopstart's online funding database gives your organisation an up- to-date and comprehensive overview of the most relevant subsidies, loans and fiscal stimulation programmes for your research and development projects, in real-time and free. 19
  • 20. Contact us For more information please contact one of our consultants or visit our website at www.ttopstart.com Marije aan den Toorn, PhD - consultant marije@ttopstart.com Patrick de Boer MSc. - partner patrick@ttopstart.com +316 5389 7487 ir Jasper Levink - partner jasper@ttopstart.com +316 3434 2333 Jochem Bossenbroek MSc. - partner jochem@ttopstart.com +316 2244 2641 20 ttopstart - Horizon 2020 proposal writing
  • 21.