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Renal Failure
Types ,[object Object],[object Object]
Acute renal failure ,[object Object],[object Object]
RENAL DISEASE – CLINICAL FEATURES ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Types ,[object Object],[object Object],[object Object]
 
Pre-renal ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Intra-renal ,[object Object],[object Object],[object Object],[object Object]
 
Post-renal ,[object Object],[object Object]
 
Pathogenesis ,[object Object],[object Object]
 
Renal Tubular Injury in ATN Loss of polarity and brush border   Normal epithelium with brush border
Cell death -apoptosis and necrosis  Sloughing of dead and viable cells - luminal obstruction
 
Spread and de-differentiation of viable cells   Proliferation, differentiation and reestablishment of polarity Normal epithelium with brush border
Urinary abnormalities ,[object Object]
Other abnormalities ,[object Object],[object Object],[object Object],[object Object]
Prevention and treatment ,[object Object],[object Object],[object Object],[object Object]
Dialysis ,[object Object],[object Object],[object Object]
Chronic Renal Failure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
  present absent Metabolic bone disease present absent Anemia small normal to large Kidney size polyuria oliguria Urine output polyuria, polydipsia recent drug administration, toxin exposure,surgery/hypovolemia  History Chronic Renal failure Acute renal failure
Etiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Stages ,[object Object],[object Object],[object Object],[object Object]
Stages ,[object Object],[object Object],[object Object]
Stages ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Stages ,[object Object],[object Object],[object Object],[object Object],                                                                                                
Stages ,[object Object],[object Object],[object Object],[object Object]
Pathogenesis ,[object Object],[object Object],[object Object]
Intact nephron hypothesis ,[object Object],[object Object]
Trade off hypothesis ,[object Object],[object Object]
Glomerular hyperfiltration hypothesis ,[object Object],[object Object]
Alterations of metabolism and function ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Disorders of Urine ,[object Object],[object Object],[object Object]
Disorders of Water and Sodium balance ,[object Object],[object Object],[object Object]
Disorders of Potassium balance ,[object Object],[object Object]
Metabolic Acidosis ,[object Object],[object Object],[object Object],[object Object]
 
Renal Azotemia ,[object Object],[object Object]
Renal Hypertension ,[object Object],[object Object]
Calcium, Phosphate and bone metabolism ,[object Object],[object Object],[object Object],[object Object],[object Object]
Renal anemia and bleeding tendency ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Uremia ,[object Object]
Etiology & Pathogenesis ,[object Object],[object Object],[object Object]
Urea & other small m.w. molecules ,[object Object],[object Object],[object Object],[object Object]
Middle molecules ,[object Object],[object Object],[object Object]
Polypeptide hormones ,[object Object],[object Object]
Alterations of metabolism and function ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Neuromuscular ,[object Object],[object Object],[object Object]
Cardiovascular and pulmonary ,[object Object],[object Object],[object Object],[object Object]
Hematological ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Gastro intestinal ,[object Object],[object Object],[object Object],[object Object]
Endocrine and metabolic ,[object Object],[object Object],[object Object]
Dermatologic ,[object Object],[object Object],[object Object],[object Object],[object Object]
Immunologic ,[object Object]
Prevention & treatment ,[object Object],[object Object],[object Object],[object Object]
dialysate out  dialysate in  Process of CAPD 
 
 

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Renal failure

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  • 8.
  • 9.  
  • 10.
  • 11.  
  • 12.
  • 13.  
  • 14.
  • 15.  
  • 16. Renal Tubular Injury in ATN Loss of polarity and brush border Normal epithelium with brush border
  • 17. Cell death -apoptosis and necrosis Sloughing of dead and viable cells - luminal obstruction
  • 18.  
  • 19. Spread and de-differentiation of viable cells Proliferation, differentiation and reestablishment of polarity Normal epithelium with brush border
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.  
  • 26.   present absent Metabolic bone disease present absent Anemia small normal to large Kidney size polyuria oliguria Urine output polyuria, polydipsia recent drug administration, toxin exposure,surgery/hypovolemia History Chronic Renal failure Acute renal failure
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.  
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.  
  • 48.
  • 49.
  • 50.
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.
  • 61.
  • 62. dialysate out dialysate in Process of CAPD 
  • 63.  
  • 64.