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Membrane Transport and the Membrane Potential www.freelivedoctor.com
Extracellular Environment ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Body Fluids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Extracellular matrix ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Extracellular matrix ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Transport across cell membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Transport across cell membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Transport across cell membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Transport across cell membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Diffusion and Osmosis ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Diffusion and Osmosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Diffusion ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Diffusion Slide number: 1 www.freelivedoctor.com Solute Solvent
Diffusion Slide number: 2 www.freelivedoctor.com Solute Solvent
Diffusion Slide number: 3 www.freelivedoctor.com
Diffusion Slide number: 4 www.freelivedoctor.com
Diffusion Through Cell Membrane ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Rate of Diffusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Osmosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Effects of Osmosis ,[object Object],www.freelivedoctor.com
H 2 0 moves by osmosis into the lower H 2 0 concentration until equilibrium is reached (270 g/l glucose). www.freelivedoctor.com
[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Molality and Osmolality ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
[object Object],[object Object],www.freelivedoctor.com
Tonicity ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tonicity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Regulation of Plasma Osmolality ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Carrier-Mediated Transport ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Facilitated Diffusion ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
Facilitated diffusion Slide number: 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Region of lower concentration Region of higher concentration www.freelivedoctor.com Cell membrane Protein carrier molecule Transported substance
Facilitated diffusion Slide number: 2 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Region of lower concentration Region of higher concentration www.freelivedoctor.com Cell membrane Protein carrier molecule
Facilitated diffusion Slide number: 3 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Region of lower concentration Region of higher concentration www.freelivedoctor.com Protein carrier molecule Transported substance
Active Transport ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Primary Active Transport ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Na +  - K +  ATP-ase Pump ,[object Object],[object Object],www.freelivedoctor.com
P Extracellular   fluid 1. Three sodium ions (Na + ) and adenosine   triphosphate (ATP) bind to the carrier protein. 2. The ATP breaks down to adenosine   diphosphate (ADP) and a phosphate (P) and   releases energy. 3 .  The carrier protein changes shape, and the   Na +  are transported across the membrane. 4 .  The Na +  diffuse away from the carrier protein. 5 .  Two potassium ions (K + ) bind to the carrier   protein. 6 .  The phosphate is released. 7 .  The carrier protein changes shape,   transporting K +  across the membrane, and the   K +  diffuse away from the carrier protein. The   carrier protein can again bind to Na +  and ATP. Cytoplasm Na + ATP K + ADP 1 3 Na + Na + K + P K + 4 5 6 7 www.freelivedoctor.com Breakdown of ATP (releases energy) Carrier protein changes shape (requires energy) 2 Carrier protein resumes original shape ATP binding site Carrier protein
Extracellular   fluid Three sodium ions (Na + ) and adenosine triphosphate (ATP) bind to the carrier protein. Cytoplasm Na + ATP www.freelivedoctor.com ATP binding site Carrier protein
P K + ADP Na + The ATP breaks down to adenosine diphosphate (ADP) and a phosphate (P) and releases energy. www.freelivedoctor.com Breakdown of ATP (releases energy)
K + Na + The carrier protein changes shape, and the Na +  are transported across the membrane. www.freelivedoctor.com Carrier protein changes shape (requires energy)
The Na +  diffuse away from the carrier protein. Na + www.freelivedoctor.com
Two potassium ions (K + ) bind to the carrier protein. K + www.freelivedoctor.com
The phosphate is released. P www.freelivedoctor.com
The carrier protein changes shape, transporting K +  across the membrane, and the K +  diffuse away from the carrier protein. The carrier protein can again bind to Na +  and ATP. K + www.freelivedoctor.com Carrier protein resumes original shape
Secondary Active Transport ,[object Object],[object Object],www.freelivedoctor.com
Secondary  Active Transport ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Membrane Transport of Glucose ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Bulk Transport ,[object Object],[object Object],[object Object],www.freelivedoctor.com
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Membrane Potential www.freelivedoctor.com
www.freelivedoctor.com
www.freelivedoctor.com
[object Object],[object Object],[object Object],Equilibrium Potentials www.freelivedoctor.com
[object Object],www.freelivedoctor.com
Nernst Equation ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Resting Membrane Potential ,[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com

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Membranes And Transport

  • 1. Membrane Transport and the Membrane Potential www.freelivedoctor.com
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  • 4.
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  • 13. Diffusion Slide number: 1 www.freelivedoctor.com Solute Solvent
  • 14. Diffusion Slide number: 2 www.freelivedoctor.com Solute Solvent
  • 15. Diffusion Slide number: 3 www.freelivedoctor.com
  • 16. Diffusion Slide number: 4 www.freelivedoctor.com
  • 17.
  • 18.
  • 19.
  • 20.
  • 21. H 2 0 moves by osmosis into the lower H 2 0 concentration until equilibrium is reached (270 g/l glucose). www.freelivedoctor.com
  • 22.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
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  • 33. Facilitated diffusion Slide number: 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Region of lower concentration Region of higher concentration www.freelivedoctor.com Cell membrane Protein carrier molecule Transported substance
  • 34. Facilitated diffusion Slide number: 2 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Region of lower concentration Region of higher concentration www.freelivedoctor.com Cell membrane Protein carrier molecule
  • 35. Facilitated diffusion Slide number: 3 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Region of lower concentration Region of higher concentration www.freelivedoctor.com Protein carrier molecule Transported substance
  • 36.
  • 37.
  • 38.
  • 39. P Extracellular fluid 1. Three sodium ions (Na + ) and adenosine triphosphate (ATP) bind to the carrier protein. 2. The ATP breaks down to adenosine diphosphate (ADP) and a phosphate (P) and releases energy. 3 . The carrier protein changes shape, and the Na + are transported across the membrane. 4 . The Na + diffuse away from the carrier protein. 5 . Two potassium ions (K + ) bind to the carrier protein. 6 . The phosphate is released. 7 . The carrier protein changes shape, transporting K + across the membrane, and the K + diffuse away from the carrier protein. The carrier protein can again bind to Na + and ATP. Cytoplasm Na + ATP K + ADP 1 3 Na + Na + K + P K + 4 5 6 7 www.freelivedoctor.com Breakdown of ATP (releases energy) Carrier protein changes shape (requires energy) 2 Carrier protein resumes original shape ATP binding site Carrier protein
  • 40. Extracellular fluid Three sodium ions (Na + ) and adenosine triphosphate (ATP) bind to the carrier protein. Cytoplasm Na + ATP www.freelivedoctor.com ATP binding site Carrier protein
  • 41. P K + ADP Na + The ATP breaks down to adenosine diphosphate (ADP) and a phosphate (P) and releases energy. www.freelivedoctor.com Breakdown of ATP (releases energy)
  • 42. K + Na + The carrier protein changes shape, and the Na + are transported across the membrane. www.freelivedoctor.com Carrier protein changes shape (requires energy)
  • 43. The Na + diffuse away from the carrier protein. Na + www.freelivedoctor.com
  • 44. Two potassium ions (K + ) bind to the carrier protein. K + www.freelivedoctor.com
  • 45. The phosphate is released. P www.freelivedoctor.com
  • 46. The carrier protein changes shape, transporting K + across the membrane, and the K + diffuse away from the carrier protein. The carrier protein can again bind to Na + and ATP. K + www.freelivedoctor.com Carrier protein resumes original shape
  • 47.
  • 48.
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