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GENETICS.
02. The structure of DNA.
Ian Anderson
Saint Ignatius College Geelong
THE STRUCTURE OF DNA.
 Nucleic acids.
 Deoxyribonucleic acid (DNA).
 Ribonucleic acid (RNA).
Organisms use DNA as their genetic material to:
 Store information that determines the
characteristics of cells and organisms.
 Direct the synthesis of proteins essential to the
operation of the cell or organism.
 Replicate prior to reproduction by directing the
manufacture of copies of itself.
THE STRUCTURE OF DNA.
 A polymer made up of monomer units called
nucleotides.
 Each nucleotide made up of three parts.
 Sugar (Deoxyribose).
 Phosphate group.
 Nitrogen containing base.
- adenine (A) - thymine (T)
- cytosine (C) - guanine (G)
NUCLEOTIDES.
Source: Enger et al.
(2012)
1’
3’
5’
4’
2’
NUCLEOTIDES.
 Nitrogenous bases
grouped into one of two
families based on their
structure.
 Pyrimidines.
 Cytosine, Thymine (&
Uracil).
 Purines.
 Adenine & Guanine.
Source: Reece et al.
(2011)
THE STRUCTURE OF DNA.
 Double helix shape.
 Sugar-phosphate backbone.
 The two DNA strands are antiparallel to each other.
 DNA molecule coiled in a right handed spiral.
 Base pairing rule.
 Complementary bases.
 Adenine (A)  Thymine (T)
 Cytosine (C)  Guanine (G).
 Weak hydrogen bonds between base pairs.
THE STRUCTURE OF DNA.
Source: Enger et al.
(2012)
THE STRUCTURE OF RNA.
 Single-sided polynucleotide.
 Each nucleotide made up of three parts.
 Sugar (Ribose)
 Phosphate group
 Nitrogen containing base
- adenine (A) - Uracil (U)
- cytosine (C) - guanine (G)
 Sugar-phosphate backbone.
Source: Enger et al.
(2012)
THE STRUCTURE OF DNA.
 DNA molecules are very long.
 Made up of thousands to millions of base pairs.
 Each human cell contains ~2m of DNA!
 One long DNA molecule includes many genes.
 Gene = A segment of DNA that codes for the synthesis
of a particular protein.
 In humans ~20-25 000 genes.
 DNA is wrapped around histone proteins to form
chromosomes.
 Genome – the full DNA sequence of an organism.
 In humans >3 billion base pairs.
THE STRUCTURE OF DNA.
Source: Source: Enger et al. (2012)
REFERENCES.
 Enger, E.D., Ross, F.C. and Bailey, D.B. (2012).
Concepts in Biology (14th ed). Melb: McGraw Hill.
 Reece, J.B., Urry, L.A., Cain, M.L., Wasserman,
S.A., Minorsky, P.V. and Jackson, R.B. (2011).
Campbell Biology (9th ed). Sydney: Pearson
Education.
http://SICkScience10.wikispaces.com/

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Genetics - 02 The structure of DNA

  • 1. GENETICS. 02. The structure of DNA. Ian Anderson Saint Ignatius College Geelong
  • 2. THE STRUCTURE OF DNA.  Nucleic acids.  Deoxyribonucleic acid (DNA).  Ribonucleic acid (RNA). Organisms use DNA as their genetic material to:  Store information that determines the characteristics of cells and organisms.  Direct the synthesis of proteins essential to the operation of the cell or organism.  Replicate prior to reproduction by directing the manufacture of copies of itself.
  • 3. THE STRUCTURE OF DNA.  A polymer made up of monomer units called nucleotides.  Each nucleotide made up of three parts.  Sugar (Deoxyribose).  Phosphate group.  Nitrogen containing base. - adenine (A) - thymine (T) - cytosine (C) - guanine (G)
  • 4. NUCLEOTIDES. Source: Enger et al. (2012) 1’ 3’ 5’ 4’ 2’
  • 5. NUCLEOTIDES.  Nitrogenous bases grouped into one of two families based on their structure.  Pyrimidines.  Cytosine, Thymine (& Uracil).  Purines.  Adenine & Guanine. Source: Reece et al. (2011)
  • 6. THE STRUCTURE OF DNA.  Double helix shape.  Sugar-phosphate backbone.  The two DNA strands are antiparallel to each other.  DNA molecule coiled in a right handed spiral.  Base pairing rule.  Complementary bases.  Adenine (A)  Thymine (T)  Cytosine (C)  Guanine (G).  Weak hydrogen bonds between base pairs.
  • 7. THE STRUCTURE OF DNA. Source: Enger et al. (2012)
  • 8. THE STRUCTURE OF RNA.  Single-sided polynucleotide.  Each nucleotide made up of three parts.  Sugar (Ribose)  Phosphate group  Nitrogen containing base - adenine (A) - Uracil (U) - cytosine (C) - guanine (G)  Sugar-phosphate backbone. Source: Enger et al. (2012)
  • 9. THE STRUCTURE OF DNA.  DNA molecules are very long.  Made up of thousands to millions of base pairs.  Each human cell contains ~2m of DNA!  One long DNA molecule includes many genes.  Gene = A segment of DNA that codes for the synthesis of a particular protein.  In humans ~20-25 000 genes.  DNA is wrapped around histone proteins to form chromosomes.  Genome – the full DNA sequence of an organism.  In humans >3 billion base pairs.
  • 10. THE STRUCTURE OF DNA. Source: Source: Enger et al. (2012)
  • 11. REFERENCES.  Enger, E.D., Ross, F.C. and Bailey, D.B. (2012). Concepts in Biology (14th ed). Melb: McGraw Hill.  Reece, J.B., Urry, L.A., Cain, M.L., Wasserman, S.A., Minorsky, P.V. and Jackson, R.B. (2011). Campbell Biology (9th ed). Sydney: Pearson Education.

Notas do Editor

  1. Pyrimidine – C & T (& U)Purine – A & G
  2. Pyrimidine – C & T (& U)Purine – A & G
  3. Pyrimidine – C & T (& U)Purine – A & G