1. Online bioscience course for grades 6-12 Fall 2009 bio 1.0

3. Lecture 8: Biomedicine bio 1.0

4. Biomedical research: http:// www.youtube.com/watch?v =190lGflP1Fs bio 1.0

6. Germ theory of disease: The germ theory of disease, also called the pathogenic theory of medicine, is a theory that proposes that microorganisms are the cause of many diseases. Although highly controversial when first proposed, it is now a cornerstone of modern medicine and clinical microbiology, leading to such important innovations as antibiotics and hygienic practices http:// en.wikipedia.org/wiki/Germ_theory bio 1.0

7. How bacteria cause disease: http:// www.youtube.com/watch?v =0Sx51LC_wcc bio 1.0

8. Antibiotics: In common usage, an antibiotic (from the Ancient Greek: ἀντί – anti, "against", and βίος – bios, "life") is a substance or compound that kills, or inhibits the growth of, bacteria. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa. Note that antibiotics do not affect viruses… http:// en.wikipedia.org/wiki/Antibiotic bio 1.0

9. Flu attack! How a virus invades your body: http:// www.youtube.com/watch?v =Rpj0emEGShQ bio 1.0

10. Vaccination: http:// www.youtube.com/watch?v =3ykHoIKAtQI bio 1.0

11. MedlinePlus: MedlinePlus is a free Web site that provides consumer health information for patients, families, and health care providers. MedlinePlus brings together quality information from the United States National Library of Medicine, the National Institutes of Health (NIH), other U.S. government agencies, and health-related organizations. The U.S. National Library of Medicine produces and maintains MedlinePlus. http:// en.wikipedia.org/wiki/MedlinePlus bio 1.0

12. Take Home I Bacteria and viruses are the causative agents of disease and can be treated by a variety of means, including antibiotics and vaccines… Microbes and disease bio 1.0

13. Genes and disease: The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and—when possible—links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene. http:// en.wikipedia.org/wiki/Mendelian_Inheritance_in_Man bio 1.0

14. What are SNPs?: http:// www.youtube.com/watch?v =5raJePXu0OQ bio 1.0

15. 23andMe: https://www.23andme.com bio 1.0

16. What is Cancer: http:// www.youtube.com/watch?v = LEpTTolebqo bio 1.0

17. Oncogenes I: An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a tumor cell. http:// en.wikipedia.org/wiki/Oncogene bio 1.0

18. Oncogenes II: http:// www.youtube.com/watch?v = WZdErhuLCtc bio 1.0

19. How a Proto Oncogene Becomes an Oncogene: http:// www.youtube.com/watch?v =2wIVwZksIt4 bio 1.0

20. Tumor Suppressors: http:// www.youtube.com/watch?v =iLK3jy-kGvs bio 1.0

21. Metastasis: http:// www.youtube.com/watch?v =rrMq8uA_6iA bio 1.0

22. Take Home II Some diseases, such as cancer, have as their root causes mutations and variations in genes… Genes and disease bio 1.0

23. Medical imaging : Medical imaging is the technique and process used to create images of the human body (or parts and function thereof) for clinical purposes (medical procedures seeking to reveal, diagnose or examine disease) or medical science (including the study of normal anatomy and physiology). As a discipline and in its widest sense, it is part of biological imaging and incorporates radiology (in the wider sense), nuclear medicine, investigative radiological sciences, endoscopy, (medical) thermography, medical photography and microscopy (e.g. for human pathological investigations). Measurement and recording techniques which are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), Electrocardiography (EKG) and others, but which produce data susceptible to be represented as maps (i.e. containing positional information), can be seen as forms of medical imaging. http:// en.wikipedia.org/wiki/Medical_imaging bio 1.0

24. Medical Imaging presentation: http:// www.youtube.com/watch?v =SF455zziTZI bio 1.0

25. More Than Science Fiction: http:// www.youtube.com/watch?v =wjWHx2qOyOY bio 1.0

26. Take Home III Medical imaging technologies allow the visualization of medical states of the body and have become a key part of biomedicine… Medical imaging bio 1.0

27. Pharmaceuticals/Biotechnology: A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease… http:// en.wikipedia.org/wiki/Pharmaceutical_drug Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use… http:// en.wikipedia.org/wiki/Biotechnology bio 1.0

28. The Biotechnology Age: http:// www.youtube.com/watch?v =He91k5wFYcM bio 1.0

29. Take Home IV Pharmaceutical and biotechnology based drugs and treatments are the cornerstone of modern biomedicine… Pharmaceuticals/Biotechnology bio 1.0

30. Electronic medical records: An electronic medical record is usually a computerized legal medical record created in an organization that delivers care, such as a hospital and doctor's surgery http:// en.wikipedia.org/wiki/Electronic_medical_record bio 1.0

31. IBM Smarter Planet: Electronic Health Records for Evolving Healthcare: http:// www.youtube.com/watch?v =OeaksbGMp8Y bio 1.0

32. Medical records-back to the future: 1961 electronic medical records http:// www.youtube.com/watch?v =t-aiKlIc6uk bio 1.0

33. Take Home V Electronic Medical Records (EMRs) are an emerging application of information technology in the field of biomedicine… Electronic Medical Records bio 1.0

34. Next Week: The ecosystem An overview of the Earth’s biological systems… bio 1.0

35. instructor Mark E Minie PhD [email_address] bio 1.0