Synapses and drugs

What is a synapse? ,[object Object],[object Object],[object Object]

A Synapse ,[object Object],[object Object]

Neurotransmitter ,[object Object],[object Object]

Cholinergic Synapses ,[object Object],[object Object],[object Object],[object Object]

What happens at a cholinergic synapse? Stage 1 ,[object Object]

Neuromuscular Junctions ,[object Object]

Drugs ,[object Object],[object Object],[object Object]

Various effects of drugs on synapses: DRUG ACTION EFFECT Mimic a neurotransmitter Switch on a synapse Stimulate the release of a neurotransmitter Switch on a synapse Open a neuroreceptor channel Switch on a synapse Block a neuroreceptor channel Switch off a synapse Inhibit the breakdown enzyme Switch on a synapse Inhibit the Na + K + ATPase pump Stop action potentials Block the Na + or K + channels Stop action potentials

Effect of nicotine and atropine

Summary ,[object Object],[object Object],[object Object],[object Object]

Synapses and drugs

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Synapses and drugs