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Breast  Conservation Therapy IRCH-AIIMS Experience Dr. Manish Varma, Dr. SVS Deo, Dr.NK Shukla,  Dr. Vinod Raina*, Dr.GK Rath** Dept. of Surgical , Medical* and Radiation oncology**, IRCH, AIIMS, New Delhi
Evolution  of  Surgery for BC Ultra Radical Early 19 th Century Conservation,  Reconstruction 20 th century Radical Late 19 th Century
Morbidity of Mastectomy  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Evolution of Modern BCT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rationale of BCT ,[object Object],[object Object],[object Object],[object Object],[object Object]
Rationale of BCT ,[object Object],[object Object],[object Object],[object Object]
Surgery and Radiation as combined modality ,[object Object],[object Object]
Randomized Trials  - BCT  vs  MRM   Group  No  10 Yr Survival (%)  Loc. Rec(% ) BCT  -  MRM  BCT - MRM NSABP  2105  62  -  62  10  -  8 French  179  78  -  79  7  -  9 Milan  701  71  -  69  4  -  2 EORTC  903  75  -  75  13  -  9 Danish  905  79  -  82  3  -  4 NCI  237  77  -  75  17  -  9
Randomized Trials - BCT vs MRM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NCI  Consensus Conference - EBC  In early breast cancer  breast conservation treatment is not only equivalent to mastectomy but also preferable  as it preserves the breast with all the attendant psychological and breast image advantages there by enhancing quality of life.
BCT - Multidisciplinary approach ,[object Object],[object Object],[object Object],[object Object],[object Object]
Goals of  Breast  Conservation ,[object Object],[object Object],[object Object],[object Object]
Breast  Conservation Therapy Patient Selection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Contraindications to BCT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Contraindications to BCT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BCT  Surgical  Margins  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Breast Conservation Surgery Indications for Re-excision ,[object Object],[object Object],[object Object],[object Object]
Breast Conservation Therapy Radiotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Breast Conservation Therapy Tumor Bed Boost
Breast Conservation Therapy Tumor Bed Boost
Breast Conservation Therapy: Radiotherapy  ,[object Object],[object Object],[object Object],[object Object],[object Object],Group  No.  Local Failure  (%) - RT  + RT NSABP '92  1141  39  12 Ontario '92  837  26  6 Milan  '93  567  9  0.3 Sweden '94  381  20  3
BCT- Recent Advances ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BCT- Recent Advances ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BCT- Recent Advances Surgery -  Oncoplastic Techniques – BCS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Oncoplastic Techniques for BCS :  Volume Displacement
Oncoplastic Techniques for BCS :  Volume Replacement -Mini Latissimus Dorsi flap (MLDF) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mini Latissimus Dorsi flap (MLDF)
Mini Latissimus Dorsi flap (MLDF)
BCT- Recent Advances  MRI  in  BCT ,[object Object],[object Object],[object Object],[object Object]
BCT- Recent Advances  MRI  in  BCT
BCT- Recent Advances  MRI  in  BCT
BCT – Pushing Frontiers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BCT – Pushing Frontiers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BCT – Pushing Frontiers ,[object Object],[object Object],[object Object]
Mammo guided wire localization and lumpectomy
BCT – Pushing Frontiers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BCT in LABC post NACT ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BCT in LABC post NACT
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BCT in LABC post NACT
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BCT in LABC post NACT
BCT  Rates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Breast conservation therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Breast Conservation Therapy:  IRCH Treatment Protocol ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Breast Conservation Therapy:  IRCH Treatment Protocol ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Breast Conservation Therapy:  IRCH Treatment Protocol
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Breast Conservation Therapy:  IRCH Treatment Protocol
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Breast Conservation Therapy:  IRCH Treatment Protocol
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Breast Conservation Therapy:  IRCH Treatment Protocol
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Breast Conservation Therapy:  IRCH Treatment Protocol
IRCH –AIIMS Experience ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IRCH –AIIMS Experience 50% 14.7% 20.5% 6.3% 6.8% Site
IRCH –AIIMS Experience ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IRCH –AIIMS Experience ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IRCH –AIIMS Experience 5 yr DFS – 76%
IRCH –AIIMS Experience 5 yr OS – 92%
Conclusions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thank You ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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