All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
Diseases of Blood Vessels Explained
1. Diseases of The Blood
Vessels
Prepared by
DR. MARUF RAZA
Based on
Robbins and Cotran, 8th.
2. DISEASES OF BLOOD VESSELS
By two principal mechanisms:
Narrowing or complete occlusion of the
lumen.
Weakening of the walls leading to
dilatation or rupture.
7. Renal Mechanism of Blood
Pressure Control
Renin Angiotensin Mechanism
GFR (Increases reabsorption of NA)
Vascular Relaxing Factor (NO, PG)
Natriuretic Factors (Inhibit NA reabsorption)
8. Arteriosclerosis
Arteriosclerosis means “hardening of the
arteries” with arterial wall thickening and loss of
elasticity.
Arteriolosclerosis affects small arteries and
arterioles.
Monckeberg medial sclerosis characterized by
calcific deposits in muscular arteries.
Atherosclerosis.
9. ATHEROSCLEROSIS
It is the intimal lesion called atheroma that
protrude into vessel lumen
Arteries commonly affected:
• Abdominal aorta
• The coronary arteries
• The popliteal arteries
• The internal carotid arteries
• Vessesle of the circle of willis.
10. Risk Factors for Atherosclerosis
Major
Nonmodifiable
Increasing age
Male gender
Family history
Genetic abnormalities
Potentially Controllable
Hyperlipidemia
Hypertension
Cigarette smoking
Diabetes
18. True Aneurysm
Involves intact arterial wall or wall of heart
Atherosclerotic, Syphilitic aneurysm.
False Aneurysm
Defects in the vascular wall leading to
extravascular haematoma
Ventricular rupture after Myocardial Infarction
19. VASCULITIS
Vasculitis Is the vessel wall inflammation.
Mostly involves small vessels, from arterioles to
capillaries to venules
20. Classification
Large vessel vasculitis
Giant cell arteritis
Takayasu arteritis
Medium vessel Vasculitis
Polyarteritis nodosa
Kawasaki disease
Small vessel Vasculitis
Wegener Granulomatosis
Microscopic Polyangitis