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Global Experience in Building
Sustainable Healthy Communities:
       Overview from USA

    Community Health and Wellbeing Through
         Multi-Sectoral Partnerships
         Blacktown, NSW, Australia
              6 December, 2011

              John P. Foreyt, Ph.D.
            Baylor College of Medicine
                   Houston, TX
                jforeyt@bcm.edu
Increasing prevalence of obesity
           worldwide

Between 1980 & 2008, the mean BMI
worldwide increased by 0.4 kg/m² per decade
for men and 0.5 kg/m² for women
In 2008, 1.46 billion adults worldwide were
overweight or obese
Of these, 205 million men (9.8%) and 297
million women (13.8%) were obese

                      Finucane et al, Lancet, 2011
Increasing prevalence of obesity in
                USA


If the present trend is not halted, it is projected
   that by the year 2030 86.3% of adults in the
   United States will be overweight or obese.



                  Wang, Beydoun, Liang, et al. Obesity, 2008
Sectors of Society
       Science &    Arts &
      Technology Entertainment


                          Commerce
Law & Politics             & Trade


 Healthcare               Education

                Family/
              Community
Law and Politics


          “Let’s Move!” Campaign
          "In the end, as First Lady,
          this isn’t just a policy issue
          for me. This is a passion.
          This is my mission. I am
          determined to work with
          folks across this country to
          change the way a
          generation of kids thinks
          about food and nutrition."
Education
National School Lunch Program
Commerce and Trade
         Farmers’ Markets
Science & Technology
WiiFit
X-box
Kinect
Nike run
Health
Blogs
Phone Apps
Arts and Entertainment
Family/Community
            Walking School
                   Bus walk to
            "Kids used to
             school all the time,"
             Whatley says. "Now,
             it's almost
             impossible." And with
             childhood obesity
             rates on the rise,
             Whatley says
             walking is important
             because it's the
             "easiest way to
             exercise for a
             lifetime."
Health Care
Results of Lifestyle Interventions for
                 Weight Loss


“Those who complete weight-loss programs lose
  approximately 10% of their body weight, only
  to regain two-thirds of it back within one year
  and almost all of it back within 5 years”



Institute of Medicine. Weighing the options: Criteria for evaluating
                     weight management programs. 1995
Results of Lifestyle Interventions for
            Weight Loss

Weekly group sessions over 4 – 6 months
Mean post-treatment weight reductions of ~
8-10%
Attrition rates are high at 2-yrs (mean =
39%, range 20-65%)
Attrition rates beyond 2-yrs (mean = 65%)



             Perri, Foreyt, & Anton. Preventing Weight
             Regain After Weight Loss. 2008.
Results of Lifestyle Interventions:
     Pattern of Weight Regain


Weight regain occurs steadily over 2-5 yrs
Long-term follow-ups of behavioral
interventions show a reliable pattern of
gradual regaining of lost weight
Long-term losses of ≥ 5 Kg are sustained in
less than 20% of patients in behavioral
treatment

              Perri, Foreyt, & Anton. Preventing Weight
              Regain After Weight Loss. 2008.
Results of Lifestyle Interventions:
     Pattern of Weight Regain

“The difficulty associated with
  maintaining lost weight appears to
  be the result of physiological,
  environmental, and psychological
  factors that combine to facilitate a
  regaining of lost weight and an
  abandonment of weight control
  efforts.”
                Perri, Foreyt, & Anton, 2008.
Population-wide prevention of obesity


Small changes in diet and physical activity may make more
  sense than focusing on large behavioral changes

By cutting 100 calories a day, adults can prevent weight
  gain



                        Hill et al, Science, 2003; Hill, AJCN, 2009
BENEFITS OF MODEST WEIGHT LOSS


 “Several studies demonstrate that small losses…help
reduce obesity-related co-morbidities and that
improvements in these risk factors persist with
maintenance of these modest weight losses.”
                         Institute of Medicine, 1995


-  Glucose levels        -  HDL cholesterol levels
-  Insulin levels        -  LDL cholesterol levels

-  Glycated hemoglobin -  Blood pressure
-  Triglyceride levels -  Quality of life levels
Stigmatization & Discrimination


Societal beliefs that weight can be
controlled, thereby suggestive of
character deficits (lack of willpower,
laziness, and emotional problems)
Negative attitudes
“Last safe prejudice” in U.S. society



                     Rand CSW, Macgregor AMC. South Med J. 1990.
DISCRIMINATION:
      THE PAIN OF OBESITY
Former severely obese patients:
  100% preferred to be deaf, dyslexic,
  diabetic or have heart disease or bad
  acne than to be obese again
  Leg amputation was preferred by
  91.5% and blindness by 89.4%
  100% preferred to be a normal weight
  person rather than a severely obese
  multi-millionaire
        Rand CSW, Macgregor AMC. Int J Obes. 1991;15:577–579.
Psychosocial Burden of Obesity

Obese individuals often feel
misunderstood, neglected, and rejected
Obese individuals have low employment
prospects, and are denied educational,
vocational, and advancement
opportunities
Significantly poorer quality of life



       van Hout GCM., van Oudheusden I., & van Heck GL. Obes. Surg. 2004
Building Sustainable Healthy
         Communities:
        Healthy Lifestyle

A Healthy Lifestyle is All About
          Balance:

        Healthy Diet
  Healthy Physical Activity
Building Sustainable Healthy
        Communities:
       Healthy Lifestyle



UNFORTUNATELY…
Big Texan Steak Ranch
         Amarillo, Texas




72-oz Steak FREE if eaten within 1 hour
AVERAGE ADULT AMERICAN MAN



  Height:   5’ 8”
  Weight:   195 lbs
  Waist:    39.7 in.
  BMI:      28.4


                       CDC, 2011
AVERAGE ADULT AMERICAN WOMAN


     Height: 5’3”
     Weight: 165 lbs
     Waist: 37.0 in.
     BMI:    26.1


                          CDC, 201
Miss America,
2008
Kirsten Haglund
BMI: 16.29
Eliana Ramos
Age: 18
Height: 5’9”
29th OLYMPIAD
         BEIJING, CHINA


US wrestling team captain, Daniel
Cormier (211.5 lbs), hospitalized for
kidney failure as result of
dehydration related to cutting weight
(did not compete).
US boxer, Gary Russell was found
unconscious 4 days before his
Olympic bout due to cutting weight
(did not compete).
29th OLYMPIAD
         BEIJING, CHINA

         Michael Phelps
    8 Gold Medals, Swimming
Age:          23
Height:       6’4”
Weight:       195 lbs
BMI:          23.74
Daily Food Intake: 10,375 KCAL
        (15% PRO, 58% CHO, 27% FAT)
Exercise:           30 hrs/wk
2005: USDA FOOD PYRAMID



“The food pyramid
is too complicated
and has too many
messages.”
Robert Post, PhD. USDA Deputy
Director, 2011
2005: USDA FOOD PYRAMID




“It’s going to be hard not to do
 better than the current pyramid,
 which basically conveys no
 useful information.”

               Walter C. Willett, M.D.
    Chairman, Department of Nutrition
      Harvard School of Public Health
2011: USDA MY PLATE



“We are all
bombarded with so
many dietary
messages that it is
hard to find time to
sort through all this
information.”
Michelle Obama, 2011
Dietary Guidelines for Americans
  2010: Two Primary Concepts

Maintain calorie balance over time to
achieve and maintain a healthy weight
Focus on consuming nutrient-dense foods
and beverages




       Dietary Guidelines for Americans, 2010
Efficacy-based comparative dietary guidelines

                            Carb%   Fat%    Pro%


 Mediterranean Diet         45-55   25-35     20
 IOM Dietary Ref. Intakes   45-65   25-35     15
 NCEP-ATPIII                50-60   25-35     15
 Am. Dietetic Assoc.        45-65   20-35     15
PARADOX OF INCREASING OBESITY
         PREVALENCE

•  Focus on healthy eating and physical

 activity
•  Awareness of dangers of obesity, but…
• Obesity prevalence continues to rise
   • Work & commuting demands
   • Little time to exercise
   • Little time to prepare food
   • Availability of high-fat/calorie foods
Rationale for community-based interventions

• Increases in obesity prevalence due to genes?
   • Increased calories (e.g., 200 Kcal/day
    over 10 years)
   • Increased portion sizes (e.g., 22 oz.
    steaks and 44 oz. sodas)
   • Western diets in developing nations
    increase risk of obesity
READINESS TO CHANGE


“Habit is habit, and not to be
flung out of the window, but
coaxed downstairs a step at a
time.”
                   Mark Twain
Long-Term Weight Maintenance

National Weight Control Registry (N=10,000)
Survey of 3,000 members who have been in the
Registry for at least 10 years
Starting weight = 224 lbs; Average weight loss=69
lbs.
At 5 years, participants had maintained an average
weight loss=52 lbs.
At 10 years, participants had maintained an average
weight loss=51 lbs.

              Thomas, Bond, Phelan et al., TOS, 2011
Long-Term Weight Maintenance

Weight Maintainers report that they usually:
 Track their food intake
 Count calories or fat grams
 Follow a low-calorie, low fat diet (1,800 calories/day;
 less than 30% of calories from fat
 Eat breakfast regularly
 Limit the amount they eat out (about 3 times/week;
 eat fast food less than once/week)

                 Thomas, Bond, Phelan et al., TOS, 2011
Long-Term Weight Maintenance

Weight Maintainers report that they usually:
 Eat similar food regularly
 Don’t splurge much on holidays & special occasions
 Walk about one hour/day
 Watch less than 10 hours of TV a week
 Weigh themselves at least once a week

               Thomas, Bond, Phelan et al., TOS, 2011
LONG-TERM WEIGHT MAINTENANCE

Continued consumption of a low-
calorie diet with moderate fat intake

Limited fast food

High levels of physical activity

                    Phalen et al, Obesity 2006; 14: 710-716
LONG-TERM WEIGHT MAINTENANCE



"Daily weighing improved
 maintenance of weight loss,
 particularly when delivered
 face to face."

              Wing et al, NEJM 2006; 355:1563-1571
Most Promising Strategies For
 Preventing Weight Regain
 Providing multi-component
 programs with ongoing
 professional contacts
 Physical activity/exercise
 Portion control/meal replacements
 Extending treatment through
 weekly or bi-weekly sessions
 Pharmacotherapy


     Perri, Foreyt, & Anton. Preventing Weight Regain After Weight Loss. 2008.
Most Promising Strategies For
    Preventing Weight Regain

Extended treatments have shown
promise in promoting adherence to
the behaviors required for the long-
term maintenance of weight loss
Continuous care approach, focused
on reasonable long-term objectives,
appears appropriate for most
patients

     Perri, Foreyt, & Anton. Preventing Weight Regain After Weight
An Example of a successful long-term
             intervention:
         The Look AHEAD Study




     Does Weight Loss Reduce
Cardiovascular Disease and Death in
Overweight Individuals with Diabetes?
Look AHEAD

• Action for HEAlth in Diabetes
• Objective: to examine in overweight
  persons with Type 2 Diabetes, the long-
  term effects of an intensive lifestyle
  intervention program compared to
  diabetes education and support.
• 16 Centers
• 5145 overweight volunteers with
  diabetes
Look AHEAD
 Primary End Point Composite


• Cardiovascular death (including fatal
  myocardial infarction and stroke)

• Non-fatal myocardial infarction

• Non-fatal stroke
Clinical Sites
  Seattle


                                                                                         Boston
                                    Minneapolis                                           Providence
                                                                                      New York
                                                                Pittsburgh          Philadelphia
                                                                                    Baltimore
                         Denver


                                                                             Winston-Salem
                                                            Memphis
              Phoenix
Los Angeles

                                                            Birmingham
                                             Houston
                             San Antonio

                                                        Baton Rouge



                         Clinical Site                 Coordinating Center
Look AHEAD
                Participants

                        Lifestyle DSE
                       (N=2630) (N=2574)
Women                     59%     60%
Minority                  37%     37%
Age (years)               58.6    58.9
Insulin Users             14%     15%
Baseline BMI              35.9    36.0
Baseline weight (kg)      100     101
Attended 1 year exam      96%    94%*
                                   * p < .0004
Look AHEAD
         Study Interventions

• Diabetes support and education - DSE
  (control group)

• Lifestyle intervention – ILI (treatment
  group)
Look AHEAD
    Lifestyle Intervention

Goals:
  • 7% weight loss for the group (10%
    for individual)
  • 175 minutes of moderate intensity
    activity
Look AHEAD
         Lifestyle Intervention

• Diet
  – ADA, NCEP (< 30% fat, < 10% sat fat,
    >15% protein)
  – 1200-1500 (if weight <250lbs)
  – 1500-1800 (if weight >250lbs)
  – During first 4 weeks to 4 months, portion
    control (liquid meal replacements or
    structured meal plan)
Look AHEAD
         Lifestyle Intervention


• Physical Activity
  – unsupervised
  – 175 minutes moderate intensity/week
  – 5 days/week
  – walking
% Weight Loss at 1-Year
                               ILI                      DSE
                  0

                  -1
% Weight Change


                                                        0.7%
                  -2

                  -3

                  -4                       p < 0.0001
                  -5
                  -6

                  -7

                  -8
                  -9
                              8.6%

                          The Look AHEAD Research Group, Diabetes Care, 2007
% Reduction in Initial Weight by Gender
 % Reduction in Initial Weight

                                  0
                                                                                             Men
                                  -2                                                         Women

                                  -4

                                  -6
                                                                  N=1229
                                                                                               N=1197
                                  -8
                                           P<0.001
                                 -10                             N=872
                                                                                               N=830
                                 -12
                                       0       2         4         6          8         10           12
                                                               Months
                                                The Look AHEAD Research Group, Diabetes Care, 2007
Fitness Change (%) at 1-Year
                        25                20.9
Mean % Fitness Change




                        20                                             15.9

                        15                                 10.8

                        10
                              5.8

                         5


                         0
                             DSE         ILI               DSE       ILI
                              Unadjusted                   Adjusted for 1 Year
                               P<0.001                   Weight Change P<0.001

                                    The Look AHEAD Research Group, Diabetes Care, 2007
1-Year Changes in Markers of
              Diabetes Control
  Markers of Diabetes
       Control                 ILI    DSE     P-value

Hemoglobin A1c (%), BL         7.25    7.29    0.26
Hemoglobin A1c (%), Y1         6.61    7.15   <0.001
Y1 – Baseline                 -0.64   -0.14   <0.001

Fasting glucose (mg/dl), BL   151.9   153.6    0.21
Fasting glucose (mg/dl), Y1   130.4   146.4   <0.001
Y1 – Baseline                 -21.5    -7.2   <0.001

Diabetes medications, BL      86.5%   86.5%    0.93
Diabetes medications, Y1      78.6%   88.7%   <0.001
Y1 – Baseline                 -7.8%    2.2%   <0.001
1-Year Changes in Markers of
           Blood Pressure Control
Markers of Blood Pressure
         Control                    ILI    DSE     P-value

Systolic BP (mmHg), BL             128.2   129.4    0.26
Systolic BP (mmHg), Y1             121.4   126.6   <0.001
Y1 – Baseline                       -6.8    -2.8   <0.001

Diastolic BP (mmHg), BL            69.9    70.4     0.11
Diastolic BP (mmHg), Y1            67.0    68.6    <0.001
Y1 – Baseline                      -3.0    -1.8    <0.001


Antihypertensive medications, BL   75.3%   73.7%    0.23
Antihypertensive medications, Y1   75.2%   75.9%    0.54
Y1 – Baseline                      -0.1%    2.2%    0.02
1-Year Changes in Markers of                      Lipid
                Control
  Markers of Lipid Control        ILI    DSE     P-value
LDL-cholesterol (mg/dl), BL      112.2   112.4    0.78
LDL-cholesterol (mg/dl), Y1      107.0   106.7    0.74
Y1 – Baseline                     -5.2    -5.7    0.49
HDL-cholesterol (mg/dl), BL      43.5    43.6     0.80
HDL-cholesterol (mg/dl), Y1      46.9    44.9    <0.001
Y1 – Baseline                    3.4      1.4    <0.001
Triglycerides (mg/dl), BL        182.8   180.0    0.38
Triglycerides (mg/dl), Y1        152.5   165.4   <0.001
Y1 – Baseline                    -30.3   -14.6   <0.001
Lipid lowering medications, BL   49.4%   48.4%    0.52
Lipid lowering medications, Y1   53.0%   57.8%   <0.001
Y1 – Baseline                     3.7%    9.4%   <0.001
1-Year Changes in Percent of Participants
             Meeting ADA Goals
            ADA Goal                ILI    DSE     P-value
Hemoglobin A1c < 7%, BL            46.3%   45.4%    0.50
Hemoglobin A1c < 7%, Y1            72.7%   50.8%   <0.001
Y1 – Baseline                      26.4%    5.4%   <0.001
Blood pressure < 130/80 mmHg, BL   53.5%   49.9%    0.01
Blood pressure < 130.80 mmHg, Y1   68.6%   57.0%   <0.001
Y1 – Baseline                      15.1%    7.0%   <0.001
LDL-cholesterol < 100 mg/dl, BL    37.1%   36.9%    0.87
LDL-cholesterol < 100 mg/dl, Y1    43.8%   44.9%    0.45
Y1 – Baseline                       6.7%    8.0%    0.34
All three goals, BL                10.8%   9.5%     0.13
All three goals, Y1                23.6%   16.0%   <0.001
Y1 – Baseline                      12.8%    6.5%   <0.001
Mean Changes in Weight, Fitness & BP
     Averaged Over Four Years

                 DSE                  ILI                 P-value
                 Mean                Mean
Weight Loss      -0.88               -6.15               < 0.0001
(% initial wt)
Fitness          1.96                12.74                <0.0001
(% METS)
HbA1c            -0.09               -0.36               < 0.0001
SBP (mm Hg)      -2.97               -5.33               < 0.0001
DBP (mm Hg)      -2.48               -2.92                  0.012

                 Look AHEAD Research Group, Arch Int Med, 2010.
Mean Changes in Lipid Profile
       Averaged Over Four Years

                   DSE                ILI                P-value
                  Mean             Mean
HDL (mg/dl)         1.97             3.67                <0.0001
TG (mg/dl)        -19.75           -25.56                 0.0006
LDL (mg/dl)       -12.84           -11.27                  0.009
LDL (mg/dl)        -9.22            -8.75                   0.42
(Adjusting for
medication use)



                      Look AHEAD Research Group, Arch Int Med, 2010.
Percent (%) Completing Outcome
        Measures at Years 1-4
Intervention Group   Comparison Group
(ILI)                (DSE)

Year 1     97.1       Year 1    95.7
Year 2     94.9       Year 2    93.5
Year 3     94.0       Year 3    93.8
Year 4     94.1       Year 4    93.1
Look AHEAD Summary
ILI had significantly greater improvements
than DSE in all CVD risk factors averaged
across 4 years (except LDL-C)
There may be long-term beneficial effects
from this 4-year period in which ILI subjects
have been exposed to lower CVD risk factors
Longer follow-ups will determine whether
these lowered CVD risk factors can be
maintained & whether lifestyle intervention
has positive effects on CVD morbidity &
mortality
Mary J.
Female
White
56 years old at start of Look AHEAD
study
Past Medical History: Type 2 diabetes,
overweight, diverticulosis, arthritis,
sleep apnea, back pain
Mary J.
•Long term struggles:
  • Helping youngest daughter with
    personal issues and children
  • Rotator cuff problems
  • Degenerative disks in back
  • Rheumatoid arthritis
  • Diabetes
  • Physically demanding job
  • Financial struggles
8/2007:
                 grandkids
                 enter pre-
Pounds




                 school




         Years
Catherine L.

Female
White
47 years old at start of Look AHEAD
study
Past Medical History: Type 2 diabetes,
overweight, high blood pressure,
hypothyroidism, back pain
Catherine L.
Long term struggles:
•   Mother’s declining health and death
•   Multiple serious injuries
•   Sudden death of sister
•   Death of step-father
•   Declining economy
•   Children living at home
Pounds




Years
Realistic Management Goals

   5-10% weight loss
   Health, energy and fitness
   Well-being and self-esteem
   Mood and appearance
   Functional and recreational
    activity
Key Elements

Focus on health and energy
Food and physical activity diaries
Gradual increase in physical activity
Gradual reduction in dietary fat
No feelings of food deprivation
Social support groups
Recommended Strategies for Building
 Sustainable Healthy Communities:
        Overview from USA
Promote the availability of affordable healthy
food and beverages
Support healthy food and beverage choices
Encourage breastfeeding
Encourage physical activity or limit sedentary
activity among children & youth
Create safe communities that support physical
activity
Encourage communities to organize for change
Recommended Community Strategies
Strategies to Promote the Availability of Affordable
           Healthy Food and Beverages

  Increase the availability of healthier food and
  beverage choices in public service venues (e.g.,
  schools, city & county buildings, etc.)

--Insufficient evidence in school-based programs

--Associations suggest availability & increased
  consumption
Recommended Community Strategies
Strategies to Promote the Availability of Affordable
           Healthy Food and Beverages


  Improve availability of affordable healthier
  food & beverage choices in public service
  venues
--Reducing the cost of healthier foods
  increases their purchase
--Providing coupons redeemable for
  healthier foods increases their purchase
Recommended Community Strategies
Strategies to Promote the Availability of Affordable
           Healthy Food and Beverages
   Improve geographic availability of
   supermarkets in underserved areas
-- Greater access to nearby supermarkets is
   associated with healthier eating behaviors
-- Increasing the number of supermarkets in
   underserved neighborhoods increased
   real estate values, increased economic
   activity & employment, & resulted in lower
   food prices
Recommended Community Strategies
Strategies to Promote the Availability of Affordable
           Healthy Food and Beverages


  Provide incentives to food retailers to locate in
  and/or offer healthier food choices in
  underserved areas

-- Presence of retail venues that provide healthier
   foods is associated with better nutrition
-- Greater availability of supermarkets was
   associated with lower adolescent BMI scores
Recommended Community Strategies
Strategies to Promote the Availability of Affordable Healthy
                  Food and Beverages

  Improve availability of mechanisms for
  purchasing foods from farms

--Evidence supporting a direct link between
  purchasing food from farms & improved diet is
  limited
--Two studies of initiatives to encourage
  participation in farmers’ market showed
  increased intention to eat more fruits &
  vegetables but no direct evidence
Recommended Community Strategies
Strategies to Promote the Availability of Affordable Healthy
                  Food and Beverages
  Provide incentives for the production,
  distribution, and procurement of foods from local
  farms

--No evidence has been published to link local
  food production & health outcomes
--There is a current study exploring the potential
  nutritional & health benefits of eating locally
  grown foods
Recommended Community Strategies
Strategies to Support Healthy Food and Beverage Choices

   Restrict availability of less healthy foods &
   beverages in public service venues
--No peer-reviewed studies examined the impact
   designed to restrict availability of less healthy
   foods in public service venues
--21 states have policies that restrict the sale of
   competitive foods in schools beyond USDA
   regulations; however, no studies have evaluated
   the impact of the policies
Recommended Community Strategies
Strategies to Support Healthy Food and Beverage Choices

  Institute smaller portion size options in public
  service venues
--Evidence is lacking to demonstrate effectiveness
  of population-based interventions aimed at
  reducing portion sizes in public service venues
--Evidence from clinical studies in laboratories
  demonstrates decreasing portion sizes
  decreases energy intake
Recommended Community Strategies
Strategies to Support Healthy Food and Beverage Choices

  Limit advertisements of less healthy foods &
  beverages

--Little evidence is available regarding the impact
   of restricting advertising on purchasing &
   consumption of less healthy foods
--Cross-sectional time-series studies of tobacco-
   control efforts suggest an association between
   advertising bans & decreased tobacco
   consumption
Recommended Community Strategies
Strategies to Support Healthy Food and Beverage Choices

  Discourage consumption of sugar-sweetened
  beverages
--One longitudinal study of a school-based
  intervention among Native-American high school
  students showed a substantial reduction in
  sugar-sweetened beverages over a 3-year
  period
--A RCT of a home-based intervention that
  eliminated sugar-sweetened beverages showed
  reduction in BMI scores
Recommended Community Strategies
         Strategies to encourage breastfeeding

  Increase support for breastfeeding

--Evidence directly linking environmental
  interventions that support breastfeeding with
  obesity-related outcomes is lacking
--Epidemiologic studies indicate that breastfeeding
  helps prevent pediatric obesity
Recommended Community Strategies
Strategies to encourage physical activity or limit sedentary
             activity among children and youth
  Require physical education in schools

--14 studies have demonstrated that school-based
   PE was effective in increasing levels of physical
   activity and improving physical fitness
--Minimum of 150 min/wk in elementary schools,
   225 min/wk in middle schools and high schools
   throughout the school year as recommended by
   NASPE
Recommended Community Strategies
Strategies to encourage physical activity or limit sedentary
             activity among children and youth
  Increase opportunities for extracurricular
  physical activity

--Participation in after-school programs increased
   students’ level of physical activity & improved
   obesity-related outcomes (improved CV fitness,
   reduced body fat)
--2 pilot studies providing extracurricular physical
   activity showed increased levels of PA &
   decreased sedentary behavior
Recommended Community Strategies
Strategies to encourage physical activity or limit sedentary
             activity among children and youth
  Reduce screen time in public service venues

--A school-based RCT indicated that children who
  reduced their television, videotape, & video
  game use had significant decrease in BMI, tricep
  skin fold thickness, & waist circumference
  compared to controls
--Spending less time watching television is
  associated with increased physical activity
Recommended Community Strategies
Strategies to create safe communities that support physical
                           activity

  Improve access to outdoor recreational
  facilities
--Review of 108 studies indicated that access to facilities
  and programs for recreation near their homes, & time
  spent outdoors, correlated positively with increased
  physical activity among children& adults

--Perceptions that footpaths are safe for walking was
   significantly associated with adults being classified as
   physically active at a level sufficient for health benefits
Recommended Community Strategies
Strategies to create safe communities that support
                  physical activity
  Enhance infrastructure supporting
  bicycling
--Longitudinal intervention studies have
  demonstrated that improving bicycling
  infrastructure is associated with increased
  frequency of bicycling
--Cross-sectional studies indicated a significant
  association between bicycling infrastructure &
  frequency of biking
Recommended Community Strategies
Strategies to create safe communities that support
                  physical activity
  Enhance infrastructure supporting walking
--Reviews of cross-sectional studies of
   environmental correlates of physical activity &
   walking generally find a positive association
   between infrastructure supportive of walking &
   physical activity
--Identifying & creating safe routes to school,
   together with educational components,
   increased the number of students walking to
   school
Recommended Community Strategies
Strategies to create safe communities that support physical
                           activity

  Locating schools within easy walking
  distance of residential areas
--Community-scale urban design & land use policies &
   practices, including locating schools, stores, workplaces,
   & recreation areas close to residential areas, are
   effective in facilitating an increase in levels of physical
   activity
--Majority of efforts to encourage walking to school involve
   improving the routes rather than improving the location
   of schools
Recommended Community Strategies
Strategies to create safe communities that support
                  physical activity
  Improve access to public transportation
--Insufficient evidence exists to determine
  effectiveness of transportation policies in
  increasing the level of physical activity or
  improving fitness

--1 study indicated that 29% of individuals who
   walk to and from public transit achieve at least
   30 minutes of daily physical activity
Recommended Community Strategies
Strategies to create safe communities that support physical
                           activity

  Zone for mixed-use development
--Allows residential, commercial, institutional, &
  other public land uses to be located in close
  proximity to one another

--Studies using correlation analyses & regression
  models indicated that mixed land use was
  associated with increased walking & cycling
Recommended Community Strategies
Strategies to create safe communities that support physical
                           activity

  Enhance personal safety in areas where
  persons are or could be physically active

--Cross-sectional studies have demonstrated a
  negative relationship between crime rates and/or
  perceived safety & physical activity in
  neighborhoods
--Few intervention studies have evaluated the
  impact of policies & practices to improve
  personal safety on physical activity
Geospatial Mapping: Linking Urban
   Environments to Health Risk


Measure association between
environmental variables & health
risk factors
Assess relationships between
variables at different levels of
analysis
Used in conjunction with linear
analyses
Our Community Environmental Model
               of Obesity


Community Factors    Individual Factors
      Poverty          Dietary Intake
       Crime          Physical Activity
  Grocery Quality         Genetics
   Restaurants         Family History     Weight
       Parks           Stress/Coping
    Sidewalks         Eating Disorders
                                          Status
 Fast Food Outlets     Psychological
   Recreational           Problems
     Facilities
Chosen Neighborhoods

Census-block groups in the metro Kansas
City area (Missouri) were identified based on
a median income split (i.e., low and high
income) and mapped
We then matched census-block groups within
the income groups by population density and
percentage of minority representation
One matched block group per income level
was randomly selected
Prevalence of Obesity in
                                                   Block-Groups*
                                           *Age-standardized to the 1990 U.S. Census
Age-adjusted Obesity Prevalence (%)




                                      50
                                      45
                                      40
                                      35
                                      30
                                      25
                                      20
                                      15
                                      10
                                       5
                                       0

                                                         High-Income   Low-Income
Density of Environmental Factors in the
 Community Contributes to a “Toxic”
         Obesity Environment
                         18
                         16
 Density/1,000 persons




                         14
                         12
                         10
                          8
                          6
                          4
                          2
                          0
                              Fast-food      Convenience Store       Bars
                                          High-Income   Low-Income
COMMUNITY’S PERCEPTION OF SAFETY


     Somewhat Safe or Unsafe
                               40
       Percent (%) Feeling



                               35
                               30
                               25
                               20
                               15
                               10
                                5
                                0
                                    Daytime          Nighttime

                                     Low-Income   High-Income
Percent Substandard (or worse) Housing
         or Ground Conditions
        of Residential Properties



                   30
     Percent (%)




                   20

                   10

                   0
                          Structural       Grounds

                        Low-Income     High-Income
CONCLUSIONS


These data suggest that the higher
frequency of outlets providing
calorically-dense foods and alcohol may
contribute to greater obesity prevalence
in residents of low-income communities
More research is needed to thoroughly
document environmental determinants
of health and obesity
Neighborhoods, Obesity, and Diabetes:
  A Randomized Social Experiment
From 1994-1998, HUD randomly assigned
4,498 women with children living in public
housing in high-poverty urban census
tracts to one of three groups: (1) housing
vouchers redeemable only if they moved
to a low-poverty census tract; (2)
unrestricted vouchers; or (3) control group
(no vouchers)

              Ludwig et al, NEJM, 2011:365;16
Neighborhoods, Obesity, and Diabetes:
  A Randomized Social Experiment
10-12 year follow-up showed modest but
potentially important reductions in the
prevalence of extreme obesity & diabetes in the
group moving from a neighborhood with high
poverty on one of low poverty compared to the
control group
No differences between the group receiving
traditional vouchers & the control group
“Neighborhoods matter”

               Ludwig et al, NEJM, 2011:365;16
Recommended Community Strategies
Strategies to create safe communities that support physical
                           activity

  Enhance traffic safety in areas where
  persons are or could be physically active
--Community-scale urban design & land use policies to
   promote physical activity, including design components
   to improve street lighting, infrastructure projects to
   increase safety of pedestrian street crossing, and use of
   traffic calming approaches such as speed humps &
   traffic circles are effective in increasing physical activity
--Both community-scale & street-scale policies & practices
   are effective in increasing physical activity
Recommended Community Strategies
    Encourage Communities to Organize for Change

  Participate in community coalitions or
  partnerships to address obesity

--Little evidence is available to determine the
  impact of community coalitions on obesity
  prevention
--The presence of anti-smoking community
  coalitions has been associated with lower rates
  of tobacco consumption
What is the US Government doing?
Community Transformation Grants (CTG) to
       States and Communities
$103 million awarded to 61 states and
communities, including state & local government
agencies, tribes & territories, & state & local non-
profit organizations
To build capacity to implement changes for
community prevention efforts to ensure long-
term success
To implement evidence-based and practice-
based programs to improve health & wellness

                           www.cdc.gov/10/5/2011
What is the US Government doing?
 Community Transformation Grants (CTG) to
        States and Communities
Priority areas are:
  Tobacco-free living
  Active living and healthy eating
  Evidence-based quality clinical and other
  preventive health services for prevention
  and control of high blood pressure and
  high cholesterol

                            www.cdc.gov/10/5/2011
What is the US Government doing?
Community Transformation Grants (CTG) to
       States and Communities


Applicants proposed specific activities in
line with their chosen priority areas in their
applications
Grantee activities will not be finalized until
plans are negotiated with CDC by early
2012


                            www.cdc.gov/10/5/2011
What is the US Government doing?
 Community Transformation Grants (CTG) to
        States and Communities
Example of Capacity-Building Award:

 The Confederated Tribes of The Chehalis
 Reservation is receiving a $498,663 planning
 award to build capacity to support healthy
 lifestyles among their tribal population of 1,500
 in Washington State.
 Work will target tobacco-free living, active living
 and healthy eating, and quality clinical and other
 healthy services
                                www.cdc.gov/10/5/2011
What is the US Government doing?
 Community Transformation Grants (CTG) to
        States and Communities
Example of Implementation Award:

 Austin, TX, Dept of Health and Human Services
 is receiving $1,026,158 to serve Travis County
 (Austin) to expand efforts in tobacco-free living,
 active living and healthy eating, quality clinical
 and other preventive services, social and
 emotional wellness and healthy and safe
 physical environments
                               www.cdc.gov/10/5/2011
Building sustainable healthy
       communities: Bottom line
Obesity is an environmental problem
Despite progress in genetic research, public health
advances only will occur when we take the
environment seriously
Acknowledging the role of the environment in the
etiology of obesity will help us stop focusing on the
individual, which is encouraged by genetic and
biological explanations, and begin focusing on
changing the toxic environment
Until we do this, we will not make substantial
progress in addressing the epidemic of obesity

                Poston & Foreyt, Atherosclerosis, 1999
What’s the best approach?
Integrate all sectors of society into community
              change interventions
Incorporate:                    Sectors of Society
  Science & Technology
                                     Science &      Arts &
  Education                         Technology    Entertainm
                                                     ent
  Family/Community
  Healthcare             Law &
                                                          Commerce
                         Politics
                                                           & Trade
  Arts & Entertainment
  Law & Politics
  Commerce & Trade         Healthcare                   Education


                                            Family/
                                           Community
Project FIT: rationale, design and baseline characteristics of a school- and community-
based intervention to address physical activity and healthy eating among low-income
elementary school children.

Eisenmann JC, Alaimo K, Pfeiffer K, Paek HJ, Carlson JJ, Hayes H, Thompson T, Kelleher D,
Oh HJ, Orth J, Randall S, Mayfield K, Holmes D.

Source
Department of Kinesiology, Michigan State University, East Lansing, MI, USA. jce@msu.edu

Abstract
BACKGROUND:
This paper describes Project FIT, a collaboration between the public school system, local
health systems, physicians, neighborhood associations, businesses, faith-based leaders,
community agencies and university researchers to develop a multi-faceted approach to
promote physical activity and healthy eating toward the general goal of preventing and
reducing childhood obesity among children in Grand Rapids, MI, USA.
METHODS/DESIGN:
There are four overall components to Project FIT: school, community, social marketing, and
school staff wellness - all that focus on: 1) increasing access to safe and affordable physical
activity and nutrition education opportunities in the schools and surrounding neighborhoods; 2)
improving the affordability and availability of nutritious food in the neighborhoods surrounding
the schools; 3) improving the knowledge, self-efficacy, attitudes and behaviors regarding
nutrition and physical activity among school staff, parents and students; 4) impacting the
'culture' of the schools and neighborhoods to incorporate healthful values; and 5) encouraging
dialogue among all community partners to leverage existing programs and introduce new
ones.
Building sustainable healthy
            communities


“The Current Epidemics of Chronic Diseases
  are a Result of Discordance Between Our
    Ancient Genes and Modern Lifestyle.”




     Eaton et al., The Paleolithic Prescription. 1988.
Building sustainable healthy
       communities


    “Accuse not nature.
   She has done her part.
    Do Thou but Thine.”

     John Milton (1687), Paradise Lost
SECRETS OF SUCCESSFUL WEIGHT LOSS
            Every Day:

Sleep 8 hours
Eat breakfast
Walk briskly 60 minutes
Write down what you eat
Weigh
Find support
Never give up
Foreyt day1 pl3

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Foreyt day1 pl3

  • 1. Global Experience in Building Sustainable Healthy Communities: Overview from USA Community Health and Wellbeing Through Multi-Sectoral Partnerships Blacktown, NSW, Australia 6 December, 2011 John P. Foreyt, Ph.D. Baylor College of Medicine Houston, TX jforeyt@bcm.edu
  • 2. Increasing prevalence of obesity worldwide Between 1980 & 2008, the mean BMI worldwide increased by 0.4 kg/m² per decade for men and 0.5 kg/m² for women In 2008, 1.46 billion adults worldwide were overweight or obese Of these, 205 million men (9.8%) and 297 million women (13.8%) were obese Finucane et al, Lancet, 2011
  • 3. Increasing prevalence of obesity in USA If the present trend is not halted, it is projected that by the year 2030 86.3% of adults in the United States will be overweight or obese. Wang, Beydoun, Liang, et al. Obesity, 2008
  • 4.
  • 5. Sectors of Society Science & Arts & Technology Entertainment Commerce Law & Politics & Trade Healthcare Education Family/ Community
  • 6. Law and Politics “Let’s Move!” Campaign "In the end, as First Lady, this isn’t just a policy issue for me. This is a passion. This is my mission. I am determined to work with folks across this country to change the way a generation of kids thinks about food and nutrition."
  • 8. Commerce and Trade Farmers’ Markets
  • 9. Science & Technology WiiFit X-box Kinect Nike run Health Blogs Phone Apps
  • 11. Family/Community Walking School Bus walk to "Kids used to school all the time," Whatley says. "Now, it's almost impossible." And with childhood obesity rates on the rise, Whatley says walking is important because it's the "easiest way to exercise for a lifetime."
  • 13. Results of Lifestyle Interventions for Weight Loss “Those who complete weight-loss programs lose approximately 10% of their body weight, only to regain two-thirds of it back within one year and almost all of it back within 5 years” Institute of Medicine. Weighing the options: Criteria for evaluating weight management programs. 1995
  • 14. Results of Lifestyle Interventions for Weight Loss Weekly group sessions over 4 – 6 months Mean post-treatment weight reductions of ~ 8-10% Attrition rates are high at 2-yrs (mean = 39%, range 20-65%) Attrition rates beyond 2-yrs (mean = 65%) Perri, Foreyt, & Anton. Preventing Weight Regain After Weight Loss. 2008.
  • 15. Results of Lifestyle Interventions: Pattern of Weight Regain Weight regain occurs steadily over 2-5 yrs Long-term follow-ups of behavioral interventions show a reliable pattern of gradual regaining of lost weight Long-term losses of ≥ 5 Kg are sustained in less than 20% of patients in behavioral treatment Perri, Foreyt, & Anton. Preventing Weight Regain After Weight Loss. 2008.
  • 16. Results of Lifestyle Interventions: Pattern of Weight Regain “The difficulty associated with maintaining lost weight appears to be the result of physiological, environmental, and psychological factors that combine to facilitate a regaining of lost weight and an abandonment of weight control efforts.” Perri, Foreyt, & Anton, 2008.
  • 17. Population-wide prevention of obesity Small changes in diet and physical activity may make more sense than focusing on large behavioral changes By cutting 100 calories a day, adults can prevent weight gain Hill et al, Science, 2003; Hill, AJCN, 2009
  • 18. BENEFITS OF MODEST WEIGHT LOSS “Several studies demonstrate that small losses…help reduce obesity-related co-morbidities and that improvements in these risk factors persist with maintenance of these modest weight losses.” Institute of Medicine, 1995 -  Glucose levels -  HDL cholesterol levels -  Insulin levels -  LDL cholesterol levels -  Glycated hemoglobin -  Blood pressure -  Triglyceride levels -  Quality of life levels
  • 19. Stigmatization & Discrimination Societal beliefs that weight can be controlled, thereby suggestive of character deficits (lack of willpower, laziness, and emotional problems) Negative attitudes “Last safe prejudice” in U.S. society Rand CSW, Macgregor AMC. South Med J. 1990.
  • 20.
  • 21. DISCRIMINATION: THE PAIN OF OBESITY Former severely obese patients: 100% preferred to be deaf, dyslexic, diabetic or have heart disease or bad acne than to be obese again Leg amputation was preferred by 91.5% and blindness by 89.4% 100% preferred to be a normal weight person rather than a severely obese multi-millionaire Rand CSW, Macgregor AMC. Int J Obes. 1991;15:577–579.
  • 22. Psychosocial Burden of Obesity Obese individuals often feel misunderstood, neglected, and rejected Obese individuals have low employment prospects, and are denied educational, vocational, and advancement opportunities Significantly poorer quality of life van Hout GCM., van Oudheusden I., & van Heck GL. Obes. Surg. 2004
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30. Building Sustainable Healthy Communities: Healthy Lifestyle A Healthy Lifestyle is All About Balance: Healthy Diet Healthy Physical Activity
  • 31. Building Sustainable Healthy Communities: Healthy Lifestyle UNFORTUNATELY…
  • 32.
  • 33. Big Texan Steak Ranch Amarillo, Texas 72-oz Steak FREE if eaten within 1 hour
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39. AVERAGE ADULT AMERICAN MAN Height: 5’ 8” Weight: 195 lbs Waist: 39.7 in. BMI: 28.4 CDC, 2011
  • 40. AVERAGE ADULT AMERICAN WOMAN Height: 5’3” Weight: 165 lbs Waist: 37.0 in. BMI: 26.1 CDC, 201
  • 41.
  • 42.
  • 45. 29th OLYMPIAD BEIJING, CHINA US wrestling team captain, Daniel Cormier (211.5 lbs), hospitalized for kidney failure as result of dehydration related to cutting weight (did not compete). US boxer, Gary Russell was found unconscious 4 days before his Olympic bout due to cutting weight (did not compete).
  • 46. 29th OLYMPIAD BEIJING, CHINA Michael Phelps 8 Gold Medals, Swimming Age: 23 Height: 6’4” Weight: 195 lbs BMI: 23.74 Daily Food Intake: 10,375 KCAL (15% PRO, 58% CHO, 27% FAT) Exercise: 30 hrs/wk
  • 47.
  • 48. 2005: USDA FOOD PYRAMID “The food pyramid is too complicated and has too many messages.” Robert Post, PhD. USDA Deputy Director, 2011
  • 49. 2005: USDA FOOD PYRAMID “It’s going to be hard not to do better than the current pyramid, which basically conveys no useful information.” Walter C. Willett, M.D. Chairman, Department of Nutrition Harvard School of Public Health
  • 50. 2011: USDA MY PLATE “We are all bombarded with so many dietary messages that it is hard to find time to sort through all this information.” Michelle Obama, 2011
  • 51. Dietary Guidelines for Americans 2010: Two Primary Concepts Maintain calorie balance over time to achieve and maintain a healthy weight Focus on consuming nutrient-dense foods and beverages Dietary Guidelines for Americans, 2010
  • 52. Efficacy-based comparative dietary guidelines Carb% Fat% Pro% Mediterranean Diet 45-55 25-35 20 IOM Dietary Ref. Intakes 45-65 25-35 15 NCEP-ATPIII 50-60 25-35 15 Am. Dietetic Assoc. 45-65 20-35 15
  • 53. PARADOX OF INCREASING OBESITY PREVALENCE •  Focus on healthy eating and physical activity •  Awareness of dangers of obesity, but… • Obesity prevalence continues to rise • Work & commuting demands • Little time to exercise • Little time to prepare food • Availability of high-fat/calorie foods
  • 54. Rationale for community-based interventions • Increases in obesity prevalence due to genes? • Increased calories (e.g., 200 Kcal/day over 10 years) • Increased portion sizes (e.g., 22 oz. steaks and 44 oz. sodas) • Western diets in developing nations increase risk of obesity
  • 55. READINESS TO CHANGE “Habit is habit, and not to be flung out of the window, but coaxed downstairs a step at a time.” Mark Twain
  • 56. Long-Term Weight Maintenance National Weight Control Registry (N=10,000) Survey of 3,000 members who have been in the Registry for at least 10 years Starting weight = 224 lbs; Average weight loss=69 lbs. At 5 years, participants had maintained an average weight loss=52 lbs. At 10 years, participants had maintained an average weight loss=51 lbs. Thomas, Bond, Phelan et al., TOS, 2011
  • 57. Long-Term Weight Maintenance Weight Maintainers report that they usually: Track their food intake Count calories or fat grams Follow a low-calorie, low fat diet (1,800 calories/day; less than 30% of calories from fat Eat breakfast regularly Limit the amount they eat out (about 3 times/week; eat fast food less than once/week) Thomas, Bond, Phelan et al., TOS, 2011
  • 58. Long-Term Weight Maintenance Weight Maintainers report that they usually: Eat similar food regularly Don’t splurge much on holidays & special occasions Walk about one hour/day Watch less than 10 hours of TV a week Weigh themselves at least once a week Thomas, Bond, Phelan et al., TOS, 2011
  • 59. LONG-TERM WEIGHT MAINTENANCE Continued consumption of a low- calorie diet with moderate fat intake Limited fast food High levels of physical activity Phalen et al, Obesity 2006; 14: 710-716
  • 60. LONG-TERM WEIGHT MAINTENANCE "Daily weighing improved maintenance of weight loss, particularly when delivered face to face." Wing et al, NEJM 2006; 355:1563-1571
  • 61. Most Promising Strategies For Preventing Weight Regain Providing multi-component programs with ongoing professional contacts Physical activity/exercise Portion control/meal replacements Extending treatment through weekly or bi-weekly sessions Pharmacotherapy Perri, Foreyt, & Anton. Preventing Weight Regain After Weight Loss. 2008.
  • 62. Most Promising Strategies For Preventing Weight Regain Extended treatments have shown promise in promoting adherence to the behaviors required for the long- term maintenance of weight loss Continuous care approach, focused on reasonable long-term objectives, appears appropriate for most patients Perri, Foreyt, & Anton. Preventing Weight Regain After Weight
  • 63. An Example of a successful long-term intervention: The Look AHEAD Study Does Weight Loss Reduce Cardiovascular Disease and Death in Overweight Individuals with Diabetes?
  • 64. Look AHEAD • Action for HEAlth in Diabetes • Objective: to examine in overweight persons with Type 2 Diabetes, the long- term effects of an intensive lifestyle intervention program compared to diabetes education and support. • 16 Centers • 5145 overweight volunteers with diabetes
  • 65. Look AHEAD Primary End Point Composite • Cardiovascular death (including fatal myocardial infarction and stroke) • Non-fatal myocardial infarction • Non-fatal stroke
  • 66. Clinical Sites Seattle Boston Minneapolis Providence New York Pittsburgh Philadelphia Baltimore Denver Winston-Salem Memphis Phoenix Los Angeles Birmingham Houston San Antonio Baton Rouge Clinical Site Coordinating Center
  • 67. Look AHEAD Participants Lifestyle DSE (N=2630) (N=2574) Women 59% 60% Minority 37% 37% Age (years) 58.6 58.9 Insulin Users 14% 15% Baseline BMI 35.9 36.0 Baseline weight (kg) 100 101 Attended 1 year exam 96% 94%* * p < .0004
  • 68. Look AHEAD Study Interventions • Diabetes support and education - DSE (control group) • Lifestyle intervention – ILI (treatment group)
  • 69. Look AHEAD Lifestyle Intervention Goals: • 7% weight loss for the group (10% for individual) • 175 minutes of moderate intensity activity
  • 70. Look AHEAD Lifestyle Intervention • Diet – ADA, NCEP (< 30% fat, < 10% sat fat, >15% protein) – 1200-1500 (if weight <250lbs) – 1500-1800 (if weight >250lbs) – During first 4 weeks to 4 months, portion control (liquid meal replacements or structured meal plan)
  • 71. Look AHEAD Lifestyle Intervention • Physical Activity – unsupervised – 175 minutes moderate intensity/week – 5 days/week – walking
  • 72. % Weight Loss at 1-Year ILI DSE 0 -1 % Weight Change 0.7% -2 -3 -4 p < 0.0001 -5 -6 -7 -8 -9 8.6% The Look AHEAD Research Group, Diabetes Care, 2007
  • 73. % Reduction in Initial Weight by Gender % Reduction in Initial Weight 0 Men -2 Women -4 -6 N=1229 N=1197 -8 P<0.001 -10 N=872 N=830 -12 0 2 4 6 8 10 12 Months The Look AHEAD Research Group, Diabetes Care, 2007
  • 74. Fitness Change (%) at 1-Year 25 20.9 Mean % Fitness Change 20 15.9 15 10.8 10 5.8 5 0 DSE ILI DSE ILI Unadjusted Adjusted for 1 Year P<0.001 Weight Change P<0.001 The Look AHEAD Research Group, Diabetes Care, 2007
  • 75. 1-Year Changes in Markers of Diabetes Control Markers of Diabetes Control ILI DSE P-value Hemoglobin A1c (%), BL 7.25 7.29 0.26 Hemoglobin A1c (%), Y1 6.61 7.15 <0.001 Y1 – Baseline -0.64 -0.14 <0.001 Fasting glucose (mg/dl), BL 151.9 153.6 0.21 Fasting glucose (mg/dl), Y1 130.4 146.4 <0.001 Y1 – Baseline -21.5 -7.2 <0.001 Diabetes medications, BL 86.5% 86.5% 0.93 Diabetes medications, Y1 78.6% 88.7% <0.001 Y1 – Baseline -7.8% 2.2% <0.001
  • 76. 1-Year Changes in Markers of Blood Pressure Control Markers of Blood Pressure Control ILI DSE P-value Systolic BP (mmHg), BL 128.2 129.4 0.26 Systolic BP (mmHg), Y1 121.4 126.6 <0.001 Y1 – Baseline -6.8 -2.8 <0.001 Diastolic BP (mmHg), BL 69.9 70.4 0.11 Diastolic BP (mmHg), Y1 67.0 68.6 <0.001 Y1 – Baseline -3.0 -1.8 <0.001 Antihypertensive medications, BL 75.3% 73.7% 0.23 Antihypertensive medications, Y1 75.2% 75.9% 0.54 Y1 – Baseline -0.1% 2.2% 0.02
  • 77. 1-Year Changes in Markers of Lipid Control Markers of Lipid Control ILI DSE P-value LDL-cholesterol (mg/dl), BL 112.2 112.4 0.78 LDL-cholesterol (mg/dl), Y1 107.0 106.7 0.74 Y1 – Baseline -5.2 -5.7 0.49 HDL-cholesterol (mg/dl), BL 43.5 43.6 0.80 HDL-cholesterol (mg/dl), Y1 46.9 44.9 <0.001 Y1 – Baseline 3.4 1.4 <0.001 Triglycerides (mg/dl), BL 182.8 180.0 0.38 Triglycerides (mg/dl), Y1 152.5 165.4 <0.001 Y1 – Baseline -30.3 -14.6 <0.001 Lipid lowering medications, BL 49.4% 48.4% 0.52 Lipid lowering medications, Y1 53.0% 57.8% <0.001 Y1 – Baseline 3.7% 9.4% <0.001
  • 78. 1-Year Changes in Percent of Participants Meeting ADA Goals ADA Goal ILI DSE P-value Hemoglobin A1c < 7%, BL 46.3% 45.4% 0.50 Hemoglobin A1c < 7%, Y1 72.7% 50.8% <0.001 Y1 – Baseline 26.4% 5.4% <0.001 Blood pressure < 130/80 mmHg, BL 53.5% 49.9% 0.01 Blood pressure < 130.80 mmHg, Y1 68.6% 57.0% <0.001 Y1 – Baseline 15.1% 7.0% <0.001 LDL-cholesterol < 100 mg/dl, BL 37.1% 36.9% 0.87 LDL-cholesterol < 100 mg/dl, Y1 43.8% 44.9% 0.45 Y1 – Baseline 6.7% 8.0% 0.34 All three goals, BL 10.8% 9.5% 0.13 All three goals, Y1 23.6% 16.0% <0.001 Y1 – Baseline 12.8% 6.5% <0.001
  • 79. Mean Changes in Weight, Fitness & BP Averaged Over Four Years DSE ILI P-value Mean Mean Weight Loss -0.88 -6.15 < 0.0001 (% initial wt) Fitness 1.96 12.74 <0.0001 (% METS) HbA1c -0.09 -0.36 < 0.0001 SBP (mm Hg) -2.97 -5.33 < 0.0001 DBP (mm Hg) -2.48 -2.92 0.012 Look AHEAD Research Group, Arch Int Med, 2010.
  • 80. Mean Changes in Lipid Profile Averaged Over Four Years DSE ILI P-value Mean Mean HDL (mg/dl) 1.97 3.67 <0.0001 TG (mg/dl) -19.75 -25.56 0.0006 LDL (mg/dl) -12.84 -11.27 0.009 LDL (mg/dl) -9.22 -8.75 0.42 (Adjusting for medication use) Look AHEAD Research Group, Arch Int Med, 2010.
  • 81. Percent (%) Completing Outcome Measures at Years 1-4 Intervention Group Comparison Group (ILI) (DSE) Year 1 97.1 Year 1 95.7 Year 2 94.9 Year 2 93.5 Year 3 94.0 Year 3 93.8 Year 4 94.1 Year 4 93.1
  • 82. Look AHEAD Summary ILI had significantly greater improvements than DSE in all CVD risk factors averaged across 4 years (except LDL-C) There may be long-term beneficial effects from this 4-year period in which ILI subjects have been exposed to lower CVD risk factors Longer follow-ups will determine whether these lowered CVD risk factors can be maintained & whether lifestyle intervention has positive effects on CVD morbidity & mortality
  • 83. Mary J. Female White 56 years old at start of Look AHEAD study Past Medical History: Type 2 diabetes, overweight, diverticulosis, arthritis, sleep apnea, back pain
  • 84.
  • 85. Mary J. •Long term struggles: • Helping youngest daughter with personal issues and children • Rotator cuff problems • Degenerative disks in back • Rheumatoid arthritis • Diabetes • Physically demanding job • Financial struggles
  • 86. 8/2007: grandkids enter pre- Pounds school Years
  • 87. Catherine L. Female White 47 years old at start of Look AHEAD study Past Medical History: Type 2 diabetes, overweight, high blood pressure, hypothyroidism, back pain
  • 88.
  • 89. Catherine L. Long term struggles: • Mother’s declining health and death • Multiple serious injuries • Sudden death of sister • Death of step-father • Declining economy • Children living at home
  • 91. Realistic Management Goals  5-10% weight loss  Health, energy and fitness  Well-being and self-esteem  Mood and appearance  Functional and recreational activity
  • 92. Key Elements Focus on health and energy Food and physical activity diaries Gradual increase in physical activity Gradual reduction in dietary fat No feelings of food deprivation Social support groups
  • 93. Recommended Strategies for Building Sustainable Healthy Communities: Overview from USA Promote the availability of affordable healthy food and beverages Support healthy food and beverage choices Encourage breastfeeding Encourage physical activity or limit sedentary activity among children & youth Create safe communities that support physical activity Encourage communities to organize for change
  • 94. Recommended Community Strategies Strategies to Promote the Availability of Affordable Healthy Food and Beverages Increase the availability of healthier food and beverage choices in public service venues (e.g., schools, city & county buildings, etc.) --Insufficient evidence in school-based programs --Associations suggest availability & increased consumption
  • 95. Recommended Community Strategies Strategies to Promote the Availability of Affordable Healthy Food and Beverages Improve availability of affordable healthier food & beverage choices in public service venues --Reducing the cost of healthier foods increases their purchase --Providing coupons redeemable for healthier foods increases their purchase
  • 96. Recommended Community Strategies Strategies to Promote the Availability of Affordable Healthy Food and Beverages Improve geographic availability of supermarkets in underserved areas -- Greater access to nearby supermarkets is associated with healthier eating behaviors -- Increasing the number of supermarkets in underserved neighborhoods increased real estate values, increased economic activity & employment, & resulted in lower food prices
  • 97. Recommended Community Strategies Strategies to Promote the Availability of Affordable Healthy Food and Beverages Provide incentives to food retailers to locate in and/or offer healthier food choices in underserved areas -- Presence of retail venues that provide healthier foods is associated with better nutrition -- Greater availability of supermarkets was associated with lower adolescent BMI scores
  • 98. Recommended Community Strategies Strategies to Promote the Availability of Affordable Healthy Food and Beverages Improve availability of mechanisms for purchasing foods from farms --Evidence supporting a direct link between purchasing food from farms & improved diet is limited --Two studies of initiatives to encourage participation in farmers’ market showed increased intention to eat more fruits & vegetables but no direct evidence
  • 99. Recommended Community Strategies Strategies to Promote the Availability of Affordable Healthy Food and Beverages Provide incentives for the production, distribution, and procurement of foods from local farms --No evidence has been published to link local food production & health outcomes --There is a current study exploring the potential nutritional & health benefits of eating locally grown foods
  • 100. Recommended Community Strategies Strategies to Support Healthy Food and Beverage Choices Restrict availability of less healthy foods & beverages in public service venues --No peer-reviewed studies examined the impact designed to restrict availability of less healthy foods in public service venues --21 states have policies that restrict the sale of competitive foods in schools beyond USDA regulations; however, no studies have evaluated the impact of the policies
  • 101. Recommended Community Strategies Strategies to Support Healthy Food and Beverage Choices Institute smaller portion size options in public service venues --Evidence is lacking to demonstrate effectiveness of population-based interventions aimed at reducing portion sizes in public service venues --Evidence from clinical studies in laboratories demonstrates decreasing portion sizes decreases energy intake
  • 102. Recommended Community Strategies Strategies to Support Healthy Food and Beverage Choices Limit advertisements of less healthy foods & beverages --Little evidence is available regarding the impact of restricting advertising on purchasing & consumption of less healthy foods --Cross-sectional time-series studies of tobacco- control efforts suggest an association between advertising bans & decreased tobacco consumption
  • 103. Recommended Community Strategies Strategies to Support Healthy Food and Beverage Choices Discourage consumption of sugar-sweetened beverages --One longitudinal study of a school-based intervention among Native-American high school students showed a substantial reduction in sugar-sweetened beverages over a 3-year period --A RCT of a home-based intervention that eliminated sugar-sweetened beverages showed reduction in BMI scores
  • 104. Recommended Community Strategies Strategies to encourage breastfeeding Increase support for breastfeeding --Evidence directly linking environmental interventions that support breastfeeding with obesity-related outcomes is lacking --Epidemiologic studies indicate that breastfeeding helps prevent pediatric obesity
  • 105. Recommended Community Strategies Strategies to encourage physical activity or limit sedentary activity among children and youth Require physical education in schools --14 studies have demonstrated that school-based PE was effective in increasing levels of physical activity and improving physical fitness --Minimum of 150 min/wk in elementary schools, 225 min/wk in middle schools and high schools throughout the school year as recommended by NASPE
  • 106. Recommended Community Strategies Strategies to encourage physical activity or limit sedentary activity among children and youth Increase opportunities for extracurricular physical activity --Participation in after-school programs increased students’ level of physical activity & improved obesity-related outcomes (improved CV fitness, reduced body fat) --2 pilot studies providing extracurricular physical activity showed increased levels of PA & decreased sedentary behavior
  • 107. Recommended Community Strategies Strategies to encourage physical activity or limit sedentary activity among children and youth Reduce screen time in public service venues --A school-based RCT indicated that children who reduced their television, videotape, & video game use had significant decrease in BMI, tricep skin fold thickness, & waist circumference compared to controls --Spending less time watching television is associated with increased physical activity
  • 108. Recommended Community Strategies Strategies to create safe communities that support physical activity Improve access to outdoor recreational facilities --Review of 108 studies indicated that access to facilities and programs for recreation near their homes, & time spent outdoors, correlated positively with increased physical activity among children& adults --Perceptions that footpaths are safe for walking was significantly associated with adults being classified as physically active at a level sufficient for health benefits
  • 109. Recommended Community Strategies Strategies to create safe communities that support physical activity Enhance infrastructure supporting bicycling --Longitudinal intervention studies have demonstrated that improving bicycling infrastructure is associated with increased frequency of bicycling --Cross-sectional studies indicated a significant association between bicycling infrastructure & frequency of biking
  • 110. Recommended Community Strategies Strategies to create safe communities that support physical activity Enhance infrastructure supporting walking --Reviews of cross-sectional studies of environmental correlates of physical activity & walking generally find a positive association between infrastructure supportive of walking & physical activity --Identifying & creating safe routes to school, together with educational components, increased the number of students walking to school
  • 111. Recommended Community Strategies Strategies to create safe communities that support physical activity Locating schools within easy walking distance of residential areas --Community-scale urban design & land use policies & practices, including locating schools, stores, workplaces, & recreation areas close to residential areas, are effective in facilitating an increase in levels of physical activity --Majority of efforts to encourage walking to school involve improving the routes rather than improving the location of schools
  • 112. Recommended Community Strategies Strategies to create safe communities that support physical activity Improve access to public transportation --Insufficient evidence exists to determine effectiveness of transportation policies in increasing the level of physical activity or improving fitness --1 study indicated that 29% of individuals who walk to and from public transit achieve at least 30 minutes of daily physical activity
  • 113. Recommended Community Strategies Strategies to create safe communities that support physical activity Zone for mixed-use development --Allows residential, commercial, institutional, & other public land uses to be located in close proximity to one another --Studies using correlation analyses & regression models indicated that mixed land use was associated with increased walking & cycling
  • 114. Recommended Community Strategies Strategies to create safe communities that support physical activity Enhance personal safety in areas where persons are or could be physically active --Cross-sectional studies have demonstrated a negative relationship between crime rates and/or perceived safety & physical activity in neighborhoods --Few intervention studies have evaluated the impact of policies & practices to improve personal safety on physical activity
  • 115. Geospatial Mapping: Linking Urban Environments to Health Risk Measure association between environmental variables & health risk factors Assess relationships between variables at different levels of analysis Used in conjunction with linear analyses
  • 116. Our Community Environmental Model of Obesity Community Factors Individual Factors Poverty Dietary Intake Crime Physical Activity Grocery Quality Genetics Restaurants Family History Weight Parks Stress/Coping Sidewalks Eating Disorders Status Fast Food Outlets Psychological Recreational Problems Facilities
  • 117. Chosen Neighborhoods Census-block groups in the metro Kansas City area (Missouri) were identified based on a median income split (i.e., low and high income) and mapped We then matched census-block groups within the income groups by population density and percentage of minority representation One matched block group per income level was randomly selected
  • 118. Prevalence of Obesity in Block-Groups* *Age-standardized to the 1990 U.S. Census Age-adjusted Obesity Prevalence (%) 50 45 40 35 30 25 20 15 10 5 0 High-Income Low-Income
  • 119. Density of Environmental Factors in the Community Contributes to a “Toxic” Obesity Environment 18 16 Density/1,000 persons 14 12 10 8 6 4 2 0 Fast-food Convenience Store Bars High-Income Low-Income
  • 120. COMMUNITY’S PERCEPTION OF SAFETY Somewhat Safe or Unsafe 40 Percent (%) Feeling 35 30 25 20 15 10 5 0 Daytime Nighttime Low-Income High-Income
  • 121. Percent Substandard (or worse) Housing or Ground Conditions of Residential Properties 30 Percent (%) 20 10 0 Structural Grounds Low-Income High-Income
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  • 124. CONCLUSIONS These data suggest that the higher frequency of outlets providing calorically-dense foods and alcohol may contribute to greater obesity prevalence in residents of low-income communities More research is needed to thoroughly document environmental determinants of health and obesity
  • 125. Neighborhoods, Obesity, and Diabetes: A Randomized Social Experiment From 1994-1998, HUD randomly assigned 4,498 women with children living in public housing in high-poverty urban census tracts to one of three groups: (1) housing vouchers redeemable only if they moved to a low-poverty census tract; (2) unrestricted vouchers; or (3) control group (no vouchers) Ludwig et al, NEJM, 2011:365;16
  • 126. Neighborhoods, Obesity, and Diabetes: A Randomized Social Experiment 10-12 year follow-up showed modest but potentially important reductions in the prevalence of extreme obesity & diabetes in the group moving from a neighborhood with high poverty on one of low poverty compared to the control group No differences between the group receiving traditional vouchers & the control group “Neighborhoods matter” Ludwig et al, NEJM, 2011:365;16
  • 127. Recommended Community Strategies Strategies to create safe communities that support physical activity Enhance traffic safety in areas where persons are or could be physically active --Community-scale urban design & land use policies to promote physical activity, including design components to improve street lighting, infrastructure projects to increase safety of pedestrian street crossing, and use of traffic calming approaches such as speed humps & traffic circles are effective in increasing physical activity --Both community-scale & street-scale policies & practices are effective in increasing physical activity
  • 128. Recommended Community Strategies Encourage Communities to Organize for Change Participate in community coalitions or partnerships to address obesity --Little evidence is available to determine the impact of community coalitions on obesity prevention --The presence of anti-smoking community coalitions has been associated with lower rates of tobacco consumption
  • 129. What is the US Government doing? Community Transformation Grants (CTG) to States and Communities $103 million awarded to 61 states and communities, including state & local government agencies, tribes & territories, & state & local non- profit organizations To build capacity to implement changes for community prevention efforts to ensure long- term success To implement evidence-based and practice- based programs to improve health & wellness www.cdc.gov/10/5/2011
  • 130. What is the US Government doing? Community Transformation Grants (CTG) to States and Communities Priority areas are: Tobacco-free living Active living and healthy eating Evidence-based quality clinical and other preventive health services for prevention and control of high blood pressure and high cholesterol www.cdc.gov/10/5/2011
  • 131. What is the US Government doing? Community Transformation Grants (CTG) to States and Communities Applicants proposed specific activities in line with their chosen priority areas in their applications Grantee activities will not be finalized until plans are negotiated with CDC by early 2012 www.cdc.gov/10/5/2011
  • 132. What is the US Government doing? Community Transformation Grants (CTG) to States and Communities Example of Capacity-Building Award: The Confederated Tribes of The Chehalis Reservation is receiving a $498,663 planning award to build capacity to support healthy lifestyles among their tribal population of 1,500 in Washington State. Work will target tobacco-free living, active living and healthy eating, and quality clinical and other healthy services www.cdc.gov/10/5/2011
  • 133. What is the US Government doing? Community Transformation Grants (CTG) to States and Communities Example of Implementation Award: Austin, TX, Dept of Health and Human Services is receiving $1,026,158 to serve Travis County (Austin) to expand efforts in tobacco-free living, active living and healthy eating, quality clinical and other preventive services, social and emotional wellness and healthy and safe physical environments www.cdc.gov/10/5/2011
  • 134. Building sustainable healthy communities: Bottom line Obesity is an environmental problem Despite progress in genetic research, public health advances only will occur when we take the environment seriously Acknowledging the role of the environment in the etiology of obesity will help us stop focusing on the individual, which is encouraged by genetic and biological explanations, and begin focusing on changing the toxic environment Until we do this, we will not make substantial progress in addressing the epidemic of obesity Poston & Foreyt, Atherosclerosis, 1999
  • 135. What’s the best approach? Integrate all sectors of society into community change interventions Incorporate: Sectors of Society Science & Technology Science & Arts & Education Technology Entertainm ent Family/Community Healthcare Law & Commerce Politics & Trade Arts & Entertainment Law & Politics Commerce & Trade Healthcare Education Family/ Community
  • 136. Project FIT: rationale, design and baseline characteristics of a school- and community- based intervention to address physical activity and healthy eating among low-income elementary school children. Eisenmann JC, Alaimo K, Pfeiffer K, Paek HJ, Carlson JJ, Hayes H, Thompson T, Kelleher D, Oh HJ, Orth J, Randall S, Mayfield K, Holmes D. Source Department of Kinesiology, Michigan State University, East Lansing, MI, USA. jce@msu.edu Abstract BACKGROUND: This paper describes Project FIT, a collaboration between the public school system, local health systems, physicians, neighborhood associations, businesses, faith-based leaders, community agencies and university researchers to develop a multi-faceted approach to promote physical activity and healthy eating toward the general goal of preventing and reducing childhood obesity among children in Grand Rapids, MI, USA. METHODS/DESIGN: There are four overall components to Project FIT: school, community, social marketing, and school staff wellness - all that focus on: 1) increasing access to safe and affordable physical activity and nutrition education opportunities in the schools and surrounding neighborhoods; 2) improving the affordability and availability of nutritious food in the neighborhoods surrounding the schools; 3) improving the knowledge, self-efficacy, attitudes and behaviors regarding nutrition and physical activity among school staff, parents and students; 4) impacting the 'culture' of the schools and neighborhoods to incorporate healthful values; and 5) encouraging dialogue among all community partners to leverage existing programs and introduce new ones.
  • 137. Building sustainable healthy communities “The Current Epidemics of Chronic Diseases are a Result of Discordance Between Our Ancient Genes and Modern Lifestyle.” Eaton et al., The Paleolithic Prescription. 1988.
  • 138. Building sustainable healthy communities “Accuse not nature. She has done her part. Do Thou but Thine.” John Milton (1687), Paradise Lost
  • 139. SECRETS OF SUCCESSFUL WEIGHT LOSS Every Day: Sleep 8 hours Eat breakfast Walk briskly 60 minutes Write down what you eat Weigh Find support Never give up