Slides for discussion of Essential Cell Biology chapter 7

1. Cell & Molecular
Biology

4. Gene Expression

5. “...the process by which
the information encoded
in a DNA sequence
is translated into a final product
that has some effect
on a cell or organism...”

6. Figure 7-2 Essential Cell Biology (© Garland Science 2010)

7. Chapter 7

8. Chapter 3

12. Transcription

13. Making RNA
from DNA

14. Figure 7-3a,b Essential Cell Biology (© Garland Science 2010)

15. Figure 7-4 Essential Cell Biology (© Garland Science 2010)

16. Figure 7- 3c Essential Cell Biology (© Garland Science 2010)

17. Table 7-1 Essential Cell Biology (© Garland Science 2010)

18. RNA Polymerase

19. Reverse Transcriptase

20. Figure 7-7 Essential Cell Biology (© Garland Science 2010)

21. Figure 7-8 Essential Cell Biology (© Garland Science 2010)

22. Bacterial
Transcription

23. Figure 7-9 Essential Cell Biology (© Garland Science 2010)

24. Promoters
and Terminators

25. Figure 7-10 Essential Cell Biology (© Garland Science 2010)

26. Figure 7-11 Essential Cell Biology (© Garland Science 2010)

27. 3 kinds of RNA polymerase
General transcription factors
More complex
transcriptional regulation
Chromatin structure

28. Table 7-2 Essential Cell Biology (© Garland Science 2010)

29. General
Transcription
Factors

30. Figure 7-12 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)

31. TFIID, TBP and
the TATA Box

32. Figure 7-13 Essential Cell Biology (© Garland Science 2010)

33. Figure 7-12 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)

34. Transcription
Initiation
Complex

35. Figure 7-12 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)

36. RNA Processing

37. Capping and
Polyadenylation

38. Figure 7-16a Essential Cell Biology (© Garland Science 2010)

39. Figure 7-16b Essential Cell Biology (© Garland Science 2010)

40. Increase stability
Aid in nuclear export
Identify RNA as mRNA
Confirm both mRNA ends are
present before translation begins

41. mRNA Splicing

42. Introns and Exons

43. Figure 7-17 Essential Cell Biology (© Garland Science 2010)

44. Figure 7-23b Essential Cell Biology (© Garland Science 2010)

45. Figure 7- 23a Essential Cell Biology (© Garland Science 2010)

46. Figure 7-18 Essential Cell Biology (© Garland Science 2010)

47. The Spliceosome

48. Figure 7-19 Essential Cell Biology (© Garland Science 2010)

49. Figure 7-20 Essential Cell Biology (© Garland Science 2010)

50. Alternative Splicing

51. Figure 7-21 Essential Cell Biology (© Garland Science 2010)

52. NOVA: Cracking the Code of Life

53. Figure 7-22 Essential Cell Biology (© Garland Science 2010)

54. Translation

55. Reverse Transcriptase

56. Figure 7-24 Essential Cell Biology (© Garland Science 2010)

57. Reading Frame

58. Figure 7-25 Essential Cell Biology (© Garland Science 2010)

59. Transfer RNA (tRNA)

60. tRNA
secondary
structure

61. tRNA
tertiary
structure

62. Figure 7-28 Essential Cell Biology (© Garland Science 2010)

63. tRNA Charging

65. tRNA Synthetase

67. Movie 7.6

68. Figure 7-29 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)

69. Figure 7-29 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)

70. Wobble base pairing

71. The Ribosome

72. Reverse Transcriptase

73. Figure 7-32 Essential Cell Biology (© Garland Science 2010)

74. Figure 7-31 Essential Cell Biology (© Garland Science 2010)

75. 2/3 RNA
1/3 Protein
Ribozyme

76. Figure 7-34 Essential Cell Biology (© Garland Science 2010)

77. Figure 7-30 Essential Cell Biology (© Garland Science 2010)

78. Initiation

79. Figure 7-35 (part 1 of 5) Essential Cell Biology (© Garland Science 2010)

80. Figure 7-35 (part 2 of 5) Essential Cell Biology (© Garland Science 2010)

81. Figure 7-35 (part 3 of 5) Essential Cell Biology (© Garland Science 2010)

82. Figure 7-35 (part 4 of 5) Essential Cell Biology (© Garland Science 2010)

83. Figure 7-35 (part 5 of 5) Essential Cell Biology (© Garland Science 2010)

84. Elongation

85. Figure 7-33 (part 1 of 5) Essential Cell Biology (© Garland Science 2010)

86. Figure 7-33 (part 5 of 5) Essential Cell Biology (© Garland Science 2010)

87. Figure 7-33 (part 2 of 5) Essential Cell Biology (© Garland Science 2010)

88. Figure 7-33 (part 3 of 5) Essential Cell Biology (© Garland Science 2010)

89. Figure 7-33 (part 4 of 5) Essential Cell Biology (© Garland Science 2010)

90. Peptidyl Transferase
(aminoacyltransferase)

91. Figure 4-1 Essential Cell Biology (© Garland Science 2010)

92. Reverse Transcriptase

93. Figure 7-29 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)

94. Movies 7.8, 7.9

95. Termination

96. Figure 7-37 (part 1 of 3) Essential Cell Biology (© Garland Science 2010)

97. Figure 7-37 (part 2 of 3) Essential Cell Biology (© Garland Science 2010)

98. Figure 7-37 (part 3 of 3) Essential Cell Biology (© Garland Science 2010)

99. Polyribosomes

100. Figure 7-38a Essential Cell Biology (© Garland Science 2010)

101. Figure 7-38b Essential Cell Biology (© Garland Science 2010)

102. Figure 7-40 (part 1 of 2) Essential Cell Biology (© Garland Science 2010)

103. Figure 7-40 (part 2 of 2) Essential Cell Biology (© Garland Science 2010)

104. Figure 7-41 Essential Cell Biology (© Garland Science 2010)

105. Posttranslational
Modification

107. Protein Precursors,
or Pro-proteins

108. Figure 7-41 Essential Cell Biology (© Garland Science 2010)

109. Protein Splicing

110. Protein Degradation