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Passive .vs. Active Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Natural active acquired immunity:  person comes down with measles Artificial active acquired immunity:  person is immunized with a vaccine Artificial passive acquired immunity:  Person receives serum with antibodies Natural passive acquired immunity:  Baby receives antibodies with mother’s milk - colostrum
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Antibodies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How an antibody operates/works? Deactivation of a bacterium by an antibody.
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Clonal Selection of B Cells is Caused by Antigenic Stimulation
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Consequences of Antibody Binding
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
Primary .vs. Secondary Immune Response
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Pathway of Specific Immune Response Pathogens Pathogens eaten by Macrophage Displays portion of Pathogen on surface Helper-T cell recognizes Pathogen   Step 1 Step 2 Step 3
Activates B- Cell Activates  Cytotoxic  T- Cell Memory B-Cell Memory T-Cell Kills Infected Cells Antibodies 
[object Object],Self protein displaying an antigen T cell receptor Interleukin-2 stimulates cell division Cytotoxic T cell Interleukin-2 activates other T cells and B cells Cell-mediated immunity (attack on infected cells) Humoral immunity (secretion of antibodies by plasma cells) B cell Helper T cell APC Interleukin-1 activates helper T cell
[object Object],Cytotoxic T cell binds to infected cell 1 2 3 Perforin makes holes in infected cell’s membrane Infected cell is destroyed INFECTED CELL Perforin molecule Cytotoxic T cell Foreign antigen Hole forming
Cellular Immunity .vs. Antibody Immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],Cellular Immunity  Antibody or Humoral Immunity
Immune Response Explained ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Immune Response Summary Displays copy of antigen on surface of cell Cellular Immunity Antibody Immunity Antigen Macrophage Helper T - Cell Active Cytotoxic T-Cell Active B  - Cell Kills Infected Cells Memory T- Cell Plasma Cell Memory B-Cell Antibodies Deactivates Antigens
Autoimmune Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HIV/AIDS Human immunodeficiency virus Attacks helper T cells Without production of IL-2, there is no second signal, and humoral and cell mediated immunity are shut off. See increase in rare diseases: TB, Kaposi sarcoma, etc.
 
Allergies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What happens during an allergic reaction? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Immediate Type Hypersensitivity ,[object Object],[object Object],[object Object]
 
Delayed Hypersensitivity A type of cell mediated immunity. Td cell – requires usual two signals Second time antigen is encountered, Td cell produces several cytokines that attract and activate macrophages, resulting in an inflammatory reaction.  Example: TB skin test

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Passive vs Active Immunity: Understanding the Key Differences

  • 1.
  • 2. Natural active acquired immunity: person comes down with measles Artificial active acquired immunity: person is immunized with a vaccine Artificial passive acquired immunity: Person receives serum with antibodies Natural passive acquired immunity: Baby receives antibodies with mother’s milk - colostrum
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9. How an antibody operates/works? Deactivation of a bacterium by an antibody.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16. Clonal Selection of B Cells is Caused by Antigenic Stimulation
  • 17.
  • 18.
  • 20.
  • 21.
  • 22. Primary .vs. Secondary Immune Response
  • 23.
  • 24.
  • 25. The Pathway of Specific Immune Response Pathogens Pathogens eaten by Macrophage Displays portion of Pathogen on surface Helper-T cell recognizes Pathogen Step 1 Step 2 Step 3
  • 26. Activates B- Cell Activates Cytotoxic T- Cell Memory B-Cell Memory T-Cell Kills Infected Cells Antibodies 
  • 27.
  • 28.
  • 29.
  • 30.
  • 31. Immune Response Summary Displays copy of antigen on surface of cell Cellular Immunity Antibody Immunity Antigen Macrophage Helper T - Cell Active Cytotoxic T-Cell Active B - Cell Kills Infected Cells Memory T- Cell Plasma Cell Memory B-Cell Antibodies Deactivates Antigens
  • 32.
  • 33. HIV/AIDS Human immunodeficiency virus Attacks helper T cells Without production of IL-2, there is no second signal, and humoral and cell mediated immunity are shut off. See increase in rare diseases: TB, Kaposi sarcoma, etc.
  • 34.  
  • 35.
  • 36.
  • 37.
  • 38.  
  • 39. Delayed Hypersensitivity A type of cell mediated immunity. Td cell – requires usual two signals Second time antigen is encountered, Td cell produces several cytokines that attract and activate macrophages, resulting in an inflammatory reaction. Example: TB skin test