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Case Presentation
    Update on controversies and research



          Alex Mitchell  Nasser Abdelmawla


alex.mitchell@leicspart.nhs.uk
alex.mitchell@leicspart.nhs.uk         Neuropsychiatry Meeting 23 August 2005
                                       Neuropsychiatry Meeting 23 August 2005
• History
   Did Wernicke and Korsakoff recognise both presentations?


• Clinical Features
   Is there a characteristic triad to Wernicke’s syndrome?
   Is amnesia focal in Korsakoff’s syndrome?


• Pathology  Pathophysiology
   Where is the lesion?
   What is the role of direct alcohol neurotoxicity?


• Treatment
   Is treatment entirely symptomatic?
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)
LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)

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LPT05 - Treatment of Wernicke-Korsakoff Syndrome (Aug 2005)

  • 1. Case Presentation Update on controversies and research Alex Mitchell Nasser Abdelmawla alex.mitchell@leicspart.nhs.uk alex.mitchell@leicspart.nhs.uk Neuropsychiatry Meeting 23 August 2005 Neuropsychiatry Meeting 23 August 2005
  • 2. • History Did Wernicke and Korsakoff recognise both presentations? • Clinical Features Is there a characteristic triad to Wernicke’s syndrome? Is amnesia focal in Korsakoff’s syndrome? • Pathology Pathophysiology Where is the lesion? What is the role of direct alcohol neurotoxicity? • Treatment Is treatment entirely symptomatic?