05 Inheritance

The Genetic Lottery ,[object Object],[object Object]

Mendel’s Pea Plants TT TT tt tt Tt Tt Tt Tt Tt Tt TT tt

Punnet Squares for: Monohybrid Crosses 1 st Generation 2 nd Generation All Tt or Tt All Tall 1 TT : 2 Tt : 1 tt or ½ TT: Tt : ½ tt 3 Tall : 1 Dwarf Genotypic ratio Phenotypic ratio T T t Tt ¼ Tt ¼ t Tt ¼ Tt ¼ T t T TT ¼ Tt ¼ t Tt ¼ tt ¼

Dihybrid Crosses ,[object Object],[object Object],[object Object],[object Object],[object Object]

Dihybrid Crosses ,[object Object],[object Object],WD Wd wD wd WD WWDD straight/detached WWDd straight/detached WwDD straight/detached WwDd straight/detached Wd WWDd straight/detached WWdd straight/attached WwDd straight/detached Wwdd straight/attached wD WwDD straight/detached WwDd straight/detached wwDD widows/detached wwDd widows/detached wd WwDd straight/detached Wwdd straight/attached wwDd widows/detached wwdd widows/attached

Dihybrid Crosses ,[object Object],[object Object],WD Wd wD wd WD WWDD straight/detached WWDd straight/detached WwDD straight/detached WwDd straight/detached Wd WWDd straight/detached WWdd straight/attached WwDd straight/detached Wwdd straight/attached wD WwDD straight/detached WwDd straight/detached wwDD widows/detached wwDd widows/detached wd WwDd straight/detached Wwdd straight/attached wwDd widows/detached wwdd straight/attached

Test Crosses ,[object Object],[object Object],[object Object],[object Object],[object Object]

Linked Genes ,[object Object],[object Object],[object Object],[object Object]

Linked Genes ,[object Object],[object Object]

Detecting Linkage ,[object Object],[object Object],[object Object],Genotype AaBb aabb Aabb aaBb Unlinked 25% 25% 25% 25% Linked 44% 44% 6% 6%

Detecting Linkage ,[object Object],[object Object],[object Object],[object Object],Distance between loci =

What can you predict from the following test cross results? ,[object Object],[object Object],[object Object],[object Object],A a B b Genotype AaBb Aabb aaBb aabb Ratio 1.1 0.9 1.2 1.0 Genotype AaBb aabb Ratio 1.0 1.0 Genotype AaBb Aabb aaBb aabb Ratio 1.0 0.45 0.55 1.0

Pedigrees – guide to symbols

Mr Jellinek’s family tree – EYE COLOUR Can you work out the genotypes for each individual?

Mr Jellinek’s family tree – EYE COLOUR bb bb bb bb bb Bb Bb Bb Bb Bb Can you work out the genotypes for each individual? Bb

Is this genetic pedigree possible, if so, explain how

1 2 4 3 Yes it is, known genotypes are shown below 5 6 7 8 bb bb bb bb bb Bb Bb Bb Bb Bb Bb Bb Bb

Autosomal Recessive ,[object Object],[object Object],[object Object],[object Object]

Autosomal Dominant ,[object Object],[object Object],[object Object],[object Object]

X-Linked Recessive ,[object Object],[object Object],[object Object],[object Object],Key features

X-Linked Dominant ,[object Object],[object Object],[object Object],[object Object]

Did yours look like this? Susan Jim Jean Scott James Natasha Alan Kylie Alison Paul Anne Emma Colin

05 Inheritance

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