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PHYSIOLOGY DEPARTMENT
Ass. Prof. VASTYANOV Rooslan
SENSORY SYSTEMS #1SENSORY SYSTEMS #1
GENERAL PROPERTIES
OF SENSORY SYSTEMS
PLEASE,
MOBILES
SHOULD
BE OFF
Reception, perception and transmission
of information
Reception, perception and transmission
of information
ANALYZER -
it`s specific sensory (receptory)
system of neurons that consist of:
• Peripheral part - receptors
• Conductive part – pathways and
afferent neurons
• Central part – cerebral cortex
Classification
of sensation organs:
• Vision organs
• Hearing organs
• Eqvilibrium organs
• Smell organs
• Taste organs
• Viscerosensation
• Touch organs
• Temperature sensation
• Pain sensation
• Posture sensation
somato-
sensory
analyzer
GENERAL STRUCTURE
OF ANALYZERS
- NEURAL ENDINGS
- RECEPTOR CELLS
- PARTICULARIZED
SENSATION ORGANS
PERIFERAL PART
CONDUCTIVE PART
CENTRAL PART
- CONDUCTIVE WAYS
- CEREBRAL STRUCTURES
Main principles of the
analyzers composition
• Each analyser has a lot of neurons levels
that are related by the pathways
• Each level has a lot of neuronal fibers –
pathways
• Each level has a different amount of the
cells – they work according principles of
convergence and divergens
• Each level has a different function:
peripheral part – reception, middle part –
conduction, central part – analyse.
MAIN PROPERTIES
OF THE ANALYSERS:
• Detection of the stimuli by receptors
• Ability to form a receptor (generator)
potential
• Perception of the stimulies according to a
definite increasing force of the irritation.
• Transmission (spreading) of the stimulies.
• Conversion information into a special system
– code
• Adaptation to stimulies
• Cortical and subcortical information analyse
2. Peripheral part of
analyzers
ANALYZER PERIPHERAL
PART
• Receptors – specific neural
cells or ending of neural
fibers that are adaptated to
perception of irritation.
Receptor classification #1
1. By localization:
- external- - internal:
- contact (taste, touch) - visceroreceptors
- distance (visual, hearing) - vestibuloreceptors (equilibrium)
- proprioreceptors (muscles)
- tissue receptors
- vessels receptors
2. By nature of irritation: 3. By adaptation:
- baroreceptors (tension) - high adaptation speed
- chemoreceptors - low adaptation speed
- thermoreceptors - nonadaptive receptors
- mechanoreceptors 4. By stimulies specifity:
- photoreceptors - adequate
- inadequate
Receptor classification #2
5. By specificity of irritation perception:
- specific receptors
- nonspecific receptors
6. By mechanism of excitation
generating:
- Primary perceptive receptors (generate GP)
- Secondary perceptive receptors (generate RP)
7. By ability to percept of irritation types:
- Monomodal receptors
- Polymodal receptors
MAIN RECEPTOR
PROPERTIES
1. EXCITABILITY – ability to excitation 
generation (RP, GP, AP) 
2.   SPECIFICITY – ability to percept only 
specific irritation 
3. Ability to TRANSFORMATE specific 
irritation in electric impulse (coding)
4. Ability to ADAPTATION – increasing of 
irritation threshold
MAIN RECEPTOR
FUNCTIONS
• Perception of the irritation
• Excitation generating
• Primary analysis of excitation
• Coding information of irritation
parameters
MECHANISM OF RECEPTOR
EXCITATION
• Irritation impulse + receptor
→↑membrane permeability for Na→
depolarization (repolarization is in
photoreceptors!) and
- generator potential (GP) develops in
primary receptors
- receptor potential (RP) develops in
secondary receptors→ RP+RP+RP=GP →
GP+GP+GP=AP
Stimulus, sensor and action potential
relationships
Graphical representation of the sensory
nerve activity in case of stimuli applying of
different intensities and durations
General properties of local
potentials (LP)
- it doesn’t spread along the nerve
fibers
- it works according to law of
gradation
- it has ability to summation
- it hasn’t refractory period
- short-time duration of LP (but RP
has long-time duration)
PRIMARY ANALYSIS IS PROVIDED
for
- Different areas of receptive fields,
- Specific perception of irritation by
receptors
- Different levels of receptor excitations
- Different levels of receptors adaptation,
- Different time of excitation development
in receptors,
- Mechanisms of feed-back connection
between receptors and neural
Coding information
• - it`s a conversion information into a
specific system – code.
Transmission of impulses is effected by
a binary code. Presence of an impulse – is 1,
its absence equals to 0.
The information about the stimulies is
transmitted in the form of individual groups or
“volleys” of impulses.
The amplitude and duration of the
individual impulses passing identical along
the same fiber, but the frequency and number
of impulses in volley may be different.
1. By change of number of AP:
If the sound has frequency less
then 1000 Hz, the cells form equal
amount of AP. If the sound has
frequency more then 1000 Hz, the
cells start to code impulses.
2. By change of impulses speed
transmission
Types of information
coding
The scheme of stimulus processing
and information coding
RECEPTORS ADAPTATION
it’s the increasing of irritation
threshold under the specific impulse
action, which acts a long period of time
Adaptation mechanisms:
- ↓amount of working receptors
- ↓ RP amplitude
- ↓ frequency of impulse conduction
- change of neural centres condition
The scheme of
adaptation of
slow- and fast-
adapting
receptors on
dependence with
their stimulation
3. Conductive part
of analyzers
COMPOSITION OF ANALYSERS
CONDUCTIVE PART
3 NEURONS:
- dendrites of 1-st sensor neurons
- axon of 1-st sensor neurons
- axon of 2-d sensor neurons (Т-neurons)
- axon of 3-d sensor neurons
Somato-sensor analyzer:
1-st neuron – spinal ganglies
2-nd neuron – cornu posterior of spinal
cord, Goll's and Burdach's nuclei
MAIN FUNCTIONS of ANALYZERS
CONDUCTIVE PART
- Excitation conduction
- Secondary analysis of
irritation
- Encoding irritation
information
LAWS OF IMPULSES
CONDUCTION in NERVES
- The law of anatomical and
physiological continuity of a
nerve
- The law of two-way
conduction
- The law of isolated
conduction along a nerve
4. Central part of
analyzers
ANALYSER CENTRAL PART
Subcortical information
analyse
Cortical information analysis
Motor areas involved with the
control of voluntary muscles
Motor speech
area (Broca`s
area)
Sensory areas involved with
cutaneous and other senses
Understanding speech, using
word
Parietal lobe
General interpretative area
Motor and sensory gyrus
Parietal
lobe
Sensory
area
Central
sulcus
Motor and sensory areas
trunk
neck
Upper arm
Lower arm
Hand, fingers,
and thumb
Upper face
Sensory areasMotor areas
FUNCTIONS OF
ANALYSERS CENTRAL
PART
- tertiary analisis of excitation
- transformation of excitation into
sensation
- formation of perceptible image
- memorization of perceptible image
PARAMETERS OF
ANALYSIS
• Intensity threshold (force) of irritation – it’s
min force of irritation, caused sensation
• Differential threshold of irritation – it’s min
force increment of irritation, caused sensation
• Spatial threshold of irritation – it’s min
distance between two irritation stimulus, that
permits these two stimulus to percept separately
The less receptive field the less spatial
threshold
• Temporal threshold – it’s min time between
two irritation stimulus, that permits these two
stimulus to percept separately
Perception of the stimulies according
a definite increasing proportion
• 1834 y. – Weber formulated the law that
states: S= a log R + b
Receptors in organism percept
difference force of the irritation if the
index between stimulies increases
according a definite proportion
100g – 3g
200g – 6g
600g – 18g
4. Proprioceptive
sensory system
MechanoreceptorsMechanoreceptors
Mechanical sensationMechanical sensation
The pacinian corpuscle is a
very rapidly adapting receptor
with a large receptive field that is
used to encode high-frequency
(100–400 Hz) vibratory sensation.
The receptor is located on the end of a
group B myelinated fiber, which is inser-
ted into an onion-like lamellar capsule
The pacinian corpuscle is a
very rapidly adapting receptor
with a large receptive field that is
used to encode high-frequency
(100–400 Hz) vibratory sensation.
The receptor is located on the end of a
group B myelinated fiber, which is inser-
ted into an onion-like lamellar capsule
The spindle-shaped Ruffini's corpuscle
is a slowly adapting receptor that
encodes pressure. It has a large
receptive field that is used to encode
the magnitude of a stimulus.
The receptor is located on the terminal
of a group B axon that is covered by a
liquid-filled collagen capsule. Collagen
strands within the capsule make contact
with the nerve fiber and the overlying skin.
The spindle-shaped Ruffini's corpuscle
is a slowly adapting receptor that
encodes pressure. It has a large
receptive field that is used to encode
the magnitude of a stimulus.
The receptor is located on the terminal
of a group B axon that is covered by a
liquid-filled collagen capsule. Collagen
strands within the capsule make contact
with the nerve fiber and the overlying skin.
Meissner's corpuscle is a rapidly
adapting receptor that participates
in the touch sensation and low-
frequency (10–100 Hz) vibration.
The receptor is located at the end of a
single group B afferent fiber that is
inserted into a small capsule.
Meissner's corpuscle is a rapidly
adapting receptor that participates
in the touch sensation and low-
frequency (10–100 Hz) vibration.
The receptor is located at the end of a
single group B afferent fiber that is
inserted into a small capsule.
Merkel’s disk is a slowly adapting
receptor with a small receptive field
that is also used to encode the
touch sensation.
The epithelial sensory cells form synaptic
connections with branches of a
single group B afferent fiber.
Merkel’s disk is a slowly adapting
receptor with a small receptive field
that is also used to encode the
touch sensation.
The epithelial sensory cells form synaptic
connections with branches of a
single group B afferent fiber.
Skin receptors localizationSkin receptors localization
Sensory systems 1

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Sensory systems 1

  • 2. SENSORY SYSTEMS #1SENSORY SYSTEMS #1 GENERAL PROPERTIES OF SENSORY SYSTEMS
  • 4. Reception, perception and transmission of information Reception, perception and transmission of information
  • 5. ANALYZER - it`s specific sensory (receptory) system of neurons that consist of: • Peripheral part - receptors • Conductive part – pathways and afferent neurons • Central part – cerebral cortex
  • 6. Classification of sensation organs: • Vision organs • Hearing organs • Eqvilibrium organs • Smell organs • Taste organs • Viscerosensation • Touch organs • Temperature sensation • Pain sensation • Posture sensation somato- sensory analyzer
  • 7. GENERAL STRUCTURE OF ANALYZERS - NEURAL ENDINGS - RECEPTOR CELLS - PARTICULARIZED SENSATION ORGANS PERIFERAL PART CONDUCTIVE PART CENTRAL PART - CONDUCTIVE WAYS - CEREBRAL STRUCTURES
  • 8. Main principles of the analyzers composition • Each analyser has a lot of neurons levels that are related by the pathways • Each level has a lot of neuronal fibers – pathways • Each level has a different amount of the cells – they work according principles of convergence and divergens • Each level has a different function: peripheral part – reception, middle part – conduction, central part – analyse.
  • 9. MAIN PROPERTIES OF THE ANALYSERS: • Detection of the stimuli by receptors • Ability to form a receptor (generator) potential • Perception of the stimulies according to a definite increasing force of the irritation. • Transmission (spreading) of the stimulies. • Conversion information into a special system – code • Adaptation to stimulies • Cortical and subcortical information analyse
  • 10. 2. Peripheral part of analyzers
  • 11. ANALYZER PERIPHERAL PART • Receptors – specific neural cells or ending of neural fibers that are adaptated to perception of irritation.
  • 12. Receptor classification #1 1. By localization: - external- - internal: - contact (taste, touch) - visceroreceptors - distance (visual, hearing) - vestibuloreceptors (equilibrium) - proprioreceptors (muscles) - tissue receptors - vessels receptors 2. By nature of irritation: 3. By adaptation: - baroreceptors (tension) - high adaptation speed - chemoreceptors - low adaptation speed - thermoreceptors - nonadaptive receptors - mechanoreceptors 4. By stimulies specifity: - photoreceptors - adequate - inadequate
  • 13. Receptor classification #2 5. By specificity of irritation perception: - specific receptors - nonspecific receptors 6. By mechanism of excitation generating: - Primary perceptive receptors (generate GP) - Secondary perceptive receptors (generate RP) 7. By ability to percept of irritation types: - Monomodal receptors - Polymodal receptors
  • 15. MAIN RECEPTOR FUNCTIONS • Perception of the irritation • Excitation generating • Primary analysis of excitation • Coding information of irritation parameters
  • 16. MECHANISM OF RECEPTOR EXCITATION • Irritation impulse + receptor →↑membrane permeability for Na→ depolarization (repolarization is in photoreceptors!) and - generator potential (GP) develops in primary receptors - receptor potential (RP) develops in secondary receptors→ RP+RP+RP=GP → GP+GP+GP=AP
  • 17. Stimulus, sensor and action potential relationships
  • 18. Graphical representation of the sensory nerve activity in case of stimuli applying of different intensities and durations
  • 19. General properties of local potentials (LP) - it doesn’t spread along the nerve fibers - it works according to law of gradation - it has ability to summation - it hasn’t refractory period - short-time duration of LP (but RP has long-time duration)
  • 20. PRIMARY ANALYSIS IS PROVIDED for - Different areas of receptive fields, - Specific perception of irritation by receptors - Different levels of receptor excitations - Different levels of receptors adaptation, - Different time of excitation development in receptors, - Mechanisms of feed-back connection between receptors and neural
  • 21. Coding information • - it`s a conversion information into a specific system – code. Transmission of impulses is effected by a binary code. Presence of an impulse – is 1, its absence equals to 0. The information about the stimulies is transmitted in the form of individual groups or “volleys” of impulses. The amplitude and duration of the individual impulses passing identical along the same fiber, but the frequency and number of impulses in volley may be different.
  • 22. 1. By change of number of AP: If the sound has frequency less then 1000 Hz, the cells form equal amount of AP. If the sound has frequency more then 1000 Hz, the cells start to code impulses. 2. By change of impulses speed transmission Types of information coding
  • 23. The scheme of stimulus processing and information coding
  • 24. RECEPTORS ADAPTATION it’s the increasing of irritation threshold under the specific impulse action, which acts a long period of time Adaptation mechanisms: - ↓amount of working receptors - ↓ RP amplitude - ↓ frequency of impulse conduction - change of neural centres condition
  • 25. The scheme of adaptation of slow- and fast- adapting receptors on dependence with their stimulation
  • 27. COMPOSITION OF ANALYSERS CONDUCTIVE PART 3 NEURONS: - dendrites of 1-st sensor neurons - axon of 1-st sensor neurons - axon of 2-d sensor neurons (Т-neurons) - axon of 3-d sensor neurons Somato-sensor analyzer: 1-st neuron – spinal ganglies 2-nd neuron – cornu posterior of spinal cord, Goll's and Burdach's nuclei
  • 28. MAIN FUNCTIONS of ANALYZERS CONDUCTIVE PART - Excitation conduction - Secondary analysis of irritation - Encoding irritation information
  • 29. LAWS OF IMPULSES CONDUCTION in NERVES - The law of anatomical and physiological continuity of a nerve - The law of two-way conduction - The law of isolated conduction along a nerve
  • 30. 4. Central part of analyzers
  • 31. ANALYSER CENTRAL PART Subcortical information analyse
  • 32. Cortical information analysis Motor areas involved with the control of voluntary muscles Motor speech area (Broca`s area) Sensory areas involved with cutaneous and other senses Understanding speech, using word Parietal lobe General interpretative area
  • 33. Motor and sensory gyrus Parietal lobe Sensory area Central sulcus
  • 34. Motor and sensory areas trunk neck Upper arm Lower arm Hand, fingers, and thumb Upper face Sensory areasMotor areas
  • 35. FUNCTIONS OF ANALYSERS CENTRAL PART - tertiary analisis of excitation - transformation of excitation into sensation - formation of perceptible image - memorization of perceptible image
  • 36. PARAMETERS OF ANALYSIS • Intensity threshold (force) of irritation – it’s min force of irritation, caused sensation • Differential threshold of irritation – it’s min force increment of irritation, caused sensation • Spatial threshold of irritation – it’s min distance between two irritation stimulus, that permits these two stimulus to percept separately The less receptive field the less spatial threshold • Temporal threshold – it’s min time between two irritation stimulus, that permits these two stimulus to percept separately
  • 37. Perception of the stimulies according a definite increasing proportion • 1834 y. – Weber formulated the law that states: S= a log R + b Receptors in organism percept difference force of the irritation if the index between stimulies increases according a definite proportion 100g – 3g 200g – 6g 600g – 18g
  • 40. Mechanical sensationMechanical sensation The pacinian corpuscle is a very rapidly adapting receptor with a large receptive field that is used to encode high-frequency (100–400 Hz) vibratory sensation. The receptor is located on the end of a group B myelinated fiber, which is inser- ted into an onion-like lamellar capsule The pacinian corpuscle is a very rapidly adapting receptor with a large receptive field that is used to encode high-frequency (100–400 Hz) vibratory sensation. The receptor is located on the end of a group B myelinated fiber, which is inser- ted into an onion-like lamellar capsule The spindle-shaped Ruffini's corpuscle is a slowly adapting receptor that encodes pressure. It has a large receptive field that is used to encode the magnitude of a stimulus. The receptor is located on the terminal of a group B axon that is covered by a liquid-filled collagen capsule. Collagen strands within the capsule make contact with the nerve fiber and the overlying skin. The spindle-shaped Ruffini's corpuscle is a slowly adapting receptor that encodes pressure. It has a large receptive field that is used to encode the magnitude of a stimulus. The receptor is located on the terminal of a group B axon that is covered by a liquid-filled collagen capsule. Collagen strands within the capsule make contact with the nerve fiber and the overlying skin. Meissner's corpuscle is a rapidly adapting receptor that participates in the touch sensation and low- frequency (10–100 Hz) vibration. The receptor is located at the end of a single group B afferent fiber that is inserted into a small capsule. Meissner's corpuscle is a rapidly adapting receptor that participates in the touch sensation and low- frequency (10–100 Hz) vibration. The receptor is located at the end of a single group B afferent fiber that is inserted into a small capsule. Merkel’s disk is a slowly adapting receptor with a small receptive field that is also used to encode the touch sensation. The epithelial sensory cells form synaptic connections with branches of a single group B afferent fiber. Merkel’s disk is a slowly adapting receptor with a small receptive field that is also used to encode the touch sensation. The epithelial sensory cells form synaptic connections with branches of a single group B afferent fiber.
  • 41. Skin receptors localizationSkin receptors localization