2. Erectile Dysfunction
Meaning :
The inability to achieve and maintain a penile
erection satisfactory for sexual intercourse
(Does not include ejaculation disorders)
3. Anatomy of the penis
• Tunica Albuginea
• Corpora Cavernosa
-- Sinusoid
• Corpus Spongiosum
-- Sinusoid
• Glans Penis
• Artrial supply
• Venous drainage
• Nerve
6. Mechanism of erection :
Dilatation arterioles&arteries
expanding of sinusoids
compression of subtunical
venular plexuses
Emissary veins enclosed
increasing of intracavernous
pressure to raise the penis
7. Mechanism of Detumescence
Transient intracorporeal pressure increase
[smooth muscle contraction]
Pressure decrease slowly
[slow reopening of the venous channels]
Pressure decrease fast
[venous outflow capacity is fully restored]
8. Neuroanatomy of penile erection
• Peripheral pathways
– autonomic [ C. Cavenosa & C. Spongiosum]
– somatic [ Glans Penis & C. Spongiosum]
Sympa, - NE release
Parasym, + NO & Ach release
Somatic, +Ach release
9. Neuroanatomy of penile erection
• Supraspinal pathways
[ hypothalamus, limbic system and cerebral cortex]
dopaminergic & adrenergic recepters promotes sexual
drive
serotonin recepters inhibits sexual
drive