Roseola infantum, also known as sixth disease or exanthem subitum, is caused by human herpesvirus 6 (HHV-6) and 7. It presents with a fever lasting 4 days accompanied by pharyngitis and cough, followed by a rash that appears for 1 day and disappears without pigmentation or desquamation. Complications are rare. It is characterized by defervescence of fever followed by appearance of the rash.

1. VYDEHI VEERAMALLA
MD BIOCHEMISTRY
OSMANIA MEDICAL COLLEGE
Roseola infantum

2. Roseola infantom, sixth disease, exanthem subitum
There are two forms of the virus which
cause Roseola, HHV-6a and HHV-7,
Complications – Sequelae
In Roseola there are almost no
complications.
There is occipital or post auricular lymphadenopathy

3. HHV6

5. Fever lasts for 4 days
Pharyngitis ,cough

7. Rsh lasts for 1 day and disppears in 1-2 days without pigmentation or
desquamation

8. Which of the follwing is true about roseola infantum
A. Defervesence follows rash
B. Caused by hhv 6,7
C. Slapped cheek appearenceis seen
D. Otitis media is common complication
E. Rash appears first on face and neck
B

9. True about Roseola infantum
A. Also called 5th disease
B. Caused by hhv 6,7
C. rash appear in trunk
D. During defervesence rash appears
B,c,d

10. A patient had fever and coryza for last 3 days developed maculopapular rash
with which lasted for 48hrs and disappeard without leaving behind pigmentation is
most commonly due to
A. Measles
B. Typhoid
C. Roseola infatum
D. Fifth disease
C

11. Fever stops and rash begins is diagnostic of
A. Fifth disease
B. Roseola infantum
C. Measles
D. Toxic shock syndrome
B