Asthma exhibits a prevalence rate ranging from 15-20% in many countries, with the United States having a prevalence rate of 7.6%. Globally, asthma affects 339 million individuals. Patients suffering from asthma often take anti-inflammatories and anticholinergics as medications. Prominent players in the asthma market include Teva Pharmaceutical Industries Ltd., Merck & Co., AstraZeneca Plc, GlaxoSmithKline Plc, Sanofi-Aventis SA, Philips Healthcare, Sunovion Pharmaceuticals, CareFusion Corporation, Inc., Boehringer Ingelheim GmbH, and Roche. Asthma is a chronic respiratory condition characterized by narrowed airways, inflammation, and excess mucus production, resulting in breathing difficulties. Causes of asthma include environmental factors, genetic predisposition, a history of viral infections, and the hygiene hypothesis. Common symptoms encompass shortness of breath, anxiety or panic, chest tightness or pain, and coughing or wheezing attacks. Diagnosis involves no single definitive test; doctors typically inquire about respiratory history and conduct physical examinations. Additional tests for lung conditions include spirometry, peak flow measurements, and various diagnostic procedures like allergy testing, sputum eosinophil assessment, methacholine challenges, nitric oxide tests (FeNO), and imaging tests. Treatment strategies encompass breathing exercises, quick-acting treatments, long-term asthma control medications, anti-inflammatories, anticholinergics, long-acting bronchodilators, and biologic therapy drugs. Medications may be administered orally or via inhalation, with corticosteroids such as fluticasone, mometasone, budesonide, ciclesonide, beclomethasone, flunisolide, and others being common choices.

1. ASTHMA
By Pranay Kumar
:- pranayraju66@gmail.com

2. ❑ Asthma Overview
▪ Executive Summary
▪ Introduction
❑ Epidemiology – Asthma
▪ Global Asthma Epidemiology
▪ Asthma Prevalence Rate – U.S
2
TableOfContent

3. Executive Summary
3
Asthma -Overview
Introduction
❑ Asthma is a chronic disease of the airways of the lungs.
❑ The airways get narrow, swell and might produce extra mucus.
❑ This results in breathing difficulties.
❑ Cause:
▪ Asthma occurs due environmental effects
▪ Inherited (genetic) factors
▪ History of viral infections
▪ Hygiene hypothesis
❑ Symptoms:
▪ Shortness of breath
▪ Anxiousness or panic
▪ Chest tightness or pain
▪ Coughing or wheezing attacks
Source: https://www.mayoclinic.org/diseases-conditions/asthma/symptoms-causes/syc-20369653 | https://www.healthline.com/health/asthma#symptoms | https://www.aaaai.org/conditions-and-
treatments/asthma
❖ The asthma have prevalence rate of 15-20 % in many countries.
❖ U.S have 7.6% of prevalence rate.
❖ Globally 339 million people are suffering from asthma.
❖ Anti-inflammatories and Anticholinergics are taken as medication
for patient suffering from asthma.
❖ Teva Pharmaceutical Industries Ltd., Merck & Co., AstraZeneca Plc,
GlaxoSmithKline Plc, Sanofi-Aventis SA, Philips Healthcare,
Sunovion Pharmaceuticals, CareFusion Corporation, Inc.,
Boehringer Ingelheim GmbH and Roche are the leading players in
asthma market.

4. Introduction
4
Asthma -Overview
❑ Treatment:
▪ Breathing exercises
▪ Quick-acting treatments
▪ Long-term asthma control medications
▪ Long-term asthma control medications
• Anti-inflammatories
• Anticholinergics
• Long-acting bronchodilators
• Biologic therapy drugs
❑ Medication are taken directly (oral) or by inhalation of corticosteroids
(fluticasone (Flovent Diskus, Flovent HFA, Arnuity Ellipta), mometasone
(Asmanex), budesonide (Pulmicort Flexhaler), ciclesonide (Alvesco),
beclomethasone (Qvar), flunisolide (Aerobid) and others).
Source: https://www.mayoclinic.org/diseases-conditions/asthma/symptoms-causes/syc-20369653 | https://www.healthline.com/health/asthma#symptoms | https://www.aaaai.org/conditions-and-
treatments/asthma
❑ Diagnosis:
❑ No single test is design to test asthma. Doctor will ask about
medical history of respiration infection and do physical
examination.
▪ Test to determine the lung conditions:
▪ Spirometry
▪ Peak flow
❑ Doctor also ask to go for different test include:
▪ Allergy testing
▪ Sputum eosinophils
▪ Methacholine challenge
▪ Nitric oxide test or FeNO test
▪ Imaging tests

5. Asthma Prevalence Rate – U.S
5
Epidemiology -Asthma
Source: https://www.who.int/news-room/fact-sheets/detail/asthma | https://www.aafa.org/asthma-facts/ | https://www.annalsofglobalhealth.org/articles/10.5334/aogh.2412/
❑ Asthma is a noncommunicable diseases, more then 339 million people are
effected with asthma globally.
❑ Globally 417,918 death occurs due to asthma and 24.6 million DALYS
(Disability-adjusted life year) attributable to Asthma.
❑ 1 in 13 people suffer from asthma according to CDC (Centers for Disease
Control and Prevention) in America.
❑ More than 25 million America suffer from asthma. In America the per
person medical cost is approx. USD $ 3,266.
❑ The prevalence rate of asthma is range from 15-20% in many countries.
U.S. Population -
2019 (Mn) 329.06 Mn
Prevalence rate -
7.6%
25.01 Mn
Global Asthma Epidemiology

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