15. Vasomotor center
V
V
AAfftteerrllooaadd
VVoolluummee
KKiiddnneeyyss
PPrreellooaadd
Renin
Ang II
b11
Aldosterone BBPP== CCOO xx TTPPVVRR
Resistance arterioles Capacitance venules
TTPPVVRR
Ang I
CCaarrddiiaacc OOuuttppuutt
HHeeaarrtt
a22
CCaa++++
LL--ttyyppee CCaa++++
cchhaannnneellss
CCaallcciiuumm CChhaannnneell
BBlloocckkeerrss
AV
b11
In interest of time we can not discuss in details all factors that may affect blood pressure level pathophysiology and
Blood pressure is controlled by an integrated system and the major elements that control the level of blood pressure are presented of this slide. Cardiac output, peripheral vascular resistance and blood volume.
CCB exert theirs clinical effects by blocking the L-class of voltage gated calcium channels. Calcium plays a critical role in cellular communication, regulation and function any manipulation of transmembrane Ca+ influx can affect variety of cellular functions and regulatoryt processes.