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Urinary Incontinence- the
Basics
Presented by:
Rhonda Walsh, MD
February 26, 2015
About Me
• Urology Residency at University of Texas-
San Antonio
• Fellowship in Female Urology/Voiding
Dysfunction at NYP-Columbia
• Operate at St. Barnabas, Overlook,
Morristown
• Also treat pelvic pain, prolapse, UTIs,
kidney stones, bladder and kidney cancer
What is incontinence?
• Incontinence is defined as “the inability
to restrain natural discharges or
evacuations of urine or feces”
• For our purposes, it refers to the
involuntary leakage of urine
Female Bladder
What does the bladder do?
• The function of the bladder is to store
urine
• In theory, the bladder should hold urine,
without leakage, until you say it is time
to empty
• This process can fail either because of
the urethra not holding urine in, or the
bladder squeezing to get urine out
Female Pelvis
Different types of incontinence
• Stress
• Urge
• Mixed
• Overflow
• Associated symptoms like frequency,
urgency, nocturia
Stress Incontinence
• Leakage of urine with increases in
abdominal pressure
• Often described as happening when
coughing or sneezing, or bending to lift
an object
• Caused by a lack of urethral support
• Often seen in women after childbearing
years- extended labor can damage the
perineal nerve worsening incontinence
in those prone to it
Urge Incontinence
• Leakage of urine when there is an urge to go to
the bathroom and one does not get there in
time
• Thought to be caused by overactive bladder
(OAB)- the bladder muscle squeezing without
permission
• Possible to have urgency without incontinence-
OAB wet vs. OAB dry
• OAB is a symptom complex that can include
urgency, frequency, incontinence, and nocturia
Other types
• Mixed incontinence- stress and urge
together
• Overflow incontinence- Leakage of
urine because bladder is full and cannot
be emptied
• Constant urine leakage following pelvic
surgery or childbirth can be due to a
fistula
How common is incontinence?
• The prevalence of incontinence in
studies ranges from 11% to 72%,
depending on the definition used
• A more accurate assessment may be
21% of women over 70 having at least
weekly incontinence
• Stress is most common (49%), followed
by mixed (29%) and urge (22%)
Risk factors
• Exercise
• Childbirth
• Obesity
• Aging
• Back injuries and neurologic problems
can contribute to bladder dysfunction
Other causes of incontinence
• Urinary tract infections sometimes cause
incontinence
• Very rarely, bladder cancer will cause the
bladder to be overactive
• It is important to see your doctor about
incontinence as it may be a sign of
another problem (sudden)
• Some medications (lithium, SSRIs)
• Diabetes can cause urgency and
frequency
Nocturia
• Defined as waking from sleep to void
• More common with age
• Caused by increased urine production
at night due to hormonal changes as
well as sleep apnea, cold
• Difficult to treat
Workup
• Making sure you empty your bladder
(ultrasound)
• Checking for urine infection
• Physical examination including pelvic exam to
make sure there are no abnormalities
• Voiding diary
• Possibly cystoscopy (looking in the bladder with
a camera)
• Urodynamic testing (looking at how the bladder
squeezes)
Physical Exam
Voiding diary
Cystoscopy
Urodynamics
How is incontinence treated?
• Behavior changes
• Exercises
• Medication (URGE)
• Surgery (STRESS)
Why is incontinence treated?
• “No one ever died from wetting their
pants”
• Caveat: sometimes increases injury and
infection in the elderly
• If incontinence is limiting your ability to
live your life, it should be treated
Treatment Algorithm
Leaking
Urge
Neuro-
modulation
Medication Botox
Stress
Biofeedback Surgery
Overflow
Behavior
Modification
Behavioral Changes
• Quitting smoking- less coughing!
• Losing weight
• Managing fluid intake- what goes in
must come out
• Managing constipation
• Managing stress and depression
Exercise Therapy
• In conjunction with behavioral
modification, can work for both types of
incontinence
• Special pelvic floor physical therapists
teach kegel exercises and do muscle
stimulation/biofeedback
Urge incontinence treatment
Urge
incontinence
Medication Urodynamics
Neuro-
modulation
Botox
Antimuscarinics
• Most common medications/least expensive
• Work on the bladder to relax it and reduce
involuntary contractions
• Reduce urgency episodes by 2-3/day and
incontinence episodes by 2/day
• Drawbacks are side effects of dry mouth
and constipation
• Used with caution in elderly due to
cognitive side effects
Mirabegron (Myrbetriq- Astellas)
• B3 agonist
• Works to increase bladder capacity
• Significantly reduces voids by 1.75/day
and incontinence episodes by 1.5/day
• NO constipation and dry mouth
• Most common side effect is elevation of
systolic blood pressure, but no more
than other bladder medications
Posterior Tibial Nerve Stimulation
• Treats frequency, urgency, and urge
incontinence
• Involves 12 weeks of 1-30 minute session a
week, then monthly maintenance
• Needle inserted into ankle stimulates the tibial
nerve
• Results are similar to medications- Decreases
incontinence episodes by 3 a day and urge
episodes by 5
PTNS (Uroplasty)
Interstim (Medtronic)
• A device placed for overactive bladder
that does not respond to medication
• Stimulates the pelvic nerves to reduce
overactivity
• Like a pacemaker for the bladder,
providing constant low-level stimulation
to override errant signals
Botulinum toxin
• Injected through a cystoscope into the
bladder wall
• Partially paralyzes the bladder
• Works for 3-6 months the first time, then
6-12 months with subsequent injections
• Decreases urge episodes by 3 and
incontinence episodes by 2/day
• Risk of urinary retention
Stress incontinence
Stress
incontinence
Mid-urethral
sling
Injectibles
Kegels
Pelvic floor muscle exercises
• 10 slow-twitch contractions and 10 fast
5 times daily
• Learn to contract these muscles at
times of increased abdominal pressure
• Works for urge incontinence as well
• 70% improvement rate, but must keep
doing them
Mid-urethral Sling
• Multiple surgeries have been done over
the years for stress incontinence
• In the past, women had open abdominal
surgery to “lift the bladder”
• Now the most common is a sling put in
through the vagina
• Often will help with mixed incontinence
• Successful in 80-90% of women
Mid-urethral sling
TVT
TOT
Vaginal Mesh
• YES it is safe in properly selected
patients
• The FDA warning is for PROLAPSE
REPAIR, not for slings
Injectibles
• Macroplastique (Uroplasty) and
Coaptite (Boston Scientific)
• Injected into the bladder neck with a
cystoscope
• Not as successful as slings,
work 40% of the time after 2
injections
Summary
• Incontinence is a common problem
• Incontinence can be treated with
minimal side effects
• If your urine leakage is bothering you,
please get it treated
Thank you
• Questions???

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Is Urinary Incontinence Dampening Your Days?

  • 1. Urinary Incontinence- the Basics Presented by: Rhonda Walsh, MD February 26, 2015
  • 2. About Me • Urology Residency at University of Texas- San Antonio • Fellowship in Female Urology/Voiding Dysfunction at NYP-Columbia • Operate at St. Barnabas, Overlook, Morristown • Also treat pelvic pain, prolapse, UTIs, kidney stones, bladder and kidney cancer
  • 3. What is incontinence? • Incontinence is defined as “the inability to restrain natural discharges or evacuations of urine or feces” • For our purposes, it refers to the involuntary leakage of urine
  • 4.
  • 6. What does the bladder do? • The function of the bladder is to store urine • In theory, the bladder should hold urine, without leakage, until you say it is time to empty • This process can fail either because of the urethra not holding urine in, or the bladder squeezing to get urine out
  • 8. Different types of incontinence • Stress • Urge • Mixed • Overflow • Associated symptoms like frequency, urgency, nocturia
  • 9. Stress Incontinence • Leakage of urine with increases in abdominal pressure • Often described as happening when coughing or sneezing, or bending to lift an object • Caused by a lack of urethral support • Often seen in women after childbearing years- extended labor can damage the perineal nerve worsening incontinence in those prone to it
  • 10.
  • 11. Urge Incontinence • Leakage of urine when there is an urge to go to the bathroom and one does not get there in time • Thought to be caused by overactive bladder (OAB)- the bladder muscle squeezing without permission • Possible to have urgency without incontinence- OAB wet vs. OAB dry • OAB is a symptom complex that can include urgency, frequency, incontinence, and nocturia
  • 12. Other types • Mixed incontinence- stress and urge together • Overflow incontinence- Leakage of urine because bladder is full and cannot be emptied • Constant urine leakage following pelvic surgery or childbirth can be due to a fistula
  • 13. How common is incontinence? • The prevalence of incontinence in studies ranges from 11% to 72%, depending on the definition used • A more accurate assessment may be 21% of women over 70 having at least weekly incontinence • Stress is most common (49%), followed by mixed (29%) and urge (22%)
  • 14. Risk factors • Exercise • Childbirth • Obesity • Aging • Back injuries and neurologic problems can contribute to bladder dysfunction
  • 15. Other causes of incontinence • Urinary tract infections sometimes cause incontinence • Very rarely, bladder cancer will cause the bladder to be overactive • It is important to see your doctor about incontinence as it may be a sign of another problem (sudden) • Some medications (lithium, SSRIs) • Diabetes can cause urgency and frequency
  • 16. Nocturia • Defined as waking from sleep to void • More common with age • Caused by increased urine production at night due to hormonal changes as well as sleep apnea, cold • Difficult to treat
  • 17. Workup • Making sure you empty your bladder (ultrasound) • Checking for urine infection • Physical examination including pelvic exam to make sure there are no abnormalities • Voiding diary • Possibly cystoscopy (looking in the bladder with a camera) • Urodynamic testing (looking at how the bladder squeezes)
  • 22. How is incontinence treated? • Behavior changes • Exercises • Medication (URGE) • Surgery (STRESS)
  • 23. Why is incontinence treated? • “No one ever died from wetting their pants” • Caveat: sometimes increases injury and infection in the elderly • If incontinence is limiting your ability to live your life, it should be treated
  • 25. Behavioral Changes • Quitting smoking- less coughing! • Losing weight • Managing fluid intake- what goes in must come out • Managing constipation • Managing stress and depression
  • 26. Exercise Therapy • In conjunction with behavioral modification, can work for both types of incontinence • Special pelvic floor physical therapists teach kegel exercises and do muscle stimulation/biofeedback
  • 27. Urge incontinence treatment Urge incontinence Medication Urodynamics Neuro- modulation Botox
  • 28. Antimuscarinics • Most common medications/least expensive • Work on the bladder to relax it and reduce involuntary contractions • Reduce urgency episodes by 2-3/day and incontinence episodes by 2/day • Drawbacks are side effects of dry mouth and constipation • Used with caution in elderly due to cognitive side effects
  • 29. Mirabegron (Myrbetriq- Astellas) • B3 agonist • Works to increase bladder capacity • Significantly reduces voids by 1.75/day and incontinence episodes by 1.5/day • NO constipation and dry mouth • Most common side effect is elevation of systolic blood pressure, but no more than other bladder medications
  • 30. Posterior Tibial Nerve Stimulation • Treats frequency, urgency, and urge incontinence • Involves 12 weeks of 1-30 minute session a week, then monthly maintenance • Needle inserted into ankle stimulates the tibial nerve • Results are similar to medications- Decreases incontinence episodes by 3 a day and urge episodes by 5
  • 32. Interstim (Medtronic) • A device placed for overactive bladder that does not respond to medication • Stimulates the pelvic nerves to reduce overactivity • Like a pacemaker for the bladder, providing constant low-level stimulation to override errant signals
  • 33.
  • 34. Botulinum toxin • Injected through a cystoscope into the bladder wall • Partially paralyzes the bladder • Works for 3-6 months the first time, then 6-12 months with subsequent injections • Decreases urge episodes by 3 and incontinence episodes by 2/day • Risk of urinary retention
  • 36. Pelvic floor muscle exercises • 10 slow-twitch contractions and 10 fast 5 times daily • Learn to contract these muscles at times of increased abdominal pressure • Works for urge incontinence as well • 70% improvement rate, but must keep doing them
  • 37. Mid-urethral Sling • Multiple surgeries have been done over the years for stress incontinence • In the past, women had open abdominal surgery to “lift the bladder” • Now the most common is a sling put in through the vagina • Often will help with mixed incontinence • Successful in 80-90% of women
  • 39.
  • 40. Vaginal Mesh • YES it is safe in properly selected patients • The FDA warning is for PROLAPSE REPAIR, not for slings
  • 41. Injectibles • Macroplastique (Uroplasty) and Coaptite (Boston Scientific) • Injected into the bladder neck with a cystoscope • Not as successful as slings, work 40% of the time after 2 injections
  • 42. Summary • Incontinence is a common problem • Incontinence can be treated with minimal side effects • If your urine leakage is bothering you, please get it treated