Anti Biotics

Notas do Editor

1. Antibiotics can be classified in a few different ways, including by their biological source , which refers to the plant, mold, soil microorganisms, or even other microorganisms from which it was derived. Or by their spectrum of action , meaning the kind of bacteria they’re effective against . Broad spectrum antibiotics are effective against a wide range of bacteria and are often given to patients as empiric treatment before the infecting organism is determined. Narrow coverage means they’re effective against specific category of bacteria, for example its effective against gram-negative or gram-positive bacteria, but not both. and if an antibiotic only works against a single type of organism or infection, it has limited coverage. They can also be classified by their mode of action , or in other words, how they fight the bacteria and we’ll go into that a bit later.
2. Used to treat Group A streptococcus – strep phayngitis, pneumococcus
3. PBPs wotj decreased affinity for penicillins e.g. mec A encodes PBP2a a high molecular weight novel penicillin binding protein. PBP2a binds beta-lactams with low affinity.