Labmatrix Software Product Slides

1. Translational Research Informatics Software System

2. Medications
Family History
Questionnaires
Demographics
Visits History
Pathology
Storage Location
Gene Expression
Proteomics
Custody History
Track all clinical & research data in a hierarchical and relational
manner that facilitates secure collaborative data entry, and easy
ad hoc data retrieval.
Etc… Etc…
Patient
Data
Biospecimen
Data
The Patient and Biospecimen data hubs in Labmatrix

3. Patient Data Capture:
•Clinical & demographics info
•Patient’s specimens & derivatives
•Phenotypes & genotypes tracking
•All other customizable study data

4. Specimen Data Capture:
•Physical measurements & desc.
•Current status & condition
•Storage location & barcodes
•Workflow processing status
•Usage & custody history

5. Calculate aliquots:
•by volume
•by mass
•by concentration
•by # of slides
Print barcodes:
•existing labels
•new GUID labels
Research BioBank 1B
Pathology Sample A597
(text-only label)
Specimen Barcoding & Aliquoting

6. - Design flexible specimen storage containers
- Batch assign & update samples to storage locations
- Generate or print freezer maps & barcode labels
Specimen Storage Management (electronic sample inventories)
Freezer Map

7. Track specimens and
their derivatives’
lineage relationship
Associate image files
and all other types of
flexible, custom-defined
data for specimens
Track Lineage, Images, and Custom-Defined Data

8. Multiple data record updates
You can update
multiple sample
records:
…via Labmatrix’s
graphic user
interface…
… or through
Excel and/or
other text editors.
(Also through our programmatic API)

9. Proprietary & Confidential
Define shortcuts to quickly
create all expected sample
records (and their derivatives)
based on your study’s specific
SOPs or workflows
“Specimen Factory”: one-click to generate all samples in your workflow

10. •Create specimen requests
•Change & monitor approval status
•Check & resolve “pull-list” items
•Update & track shipment status
Manage sample requests, inventory resolution, and shipments

11. Create any data form - tailored to your research

12. This is a scalable solution that
communicates with all data sources
Database
ETL
Framework
SOAP
tab-delimited
text
Data
Transformer
Labmatrix
Core API
Custom Web
Services
DB
SOAP
Enterprise
System
RMI APIRMI
Enterprise
System
WEB UIHTTP
DB
Large Flat
Files DB
SQL Scripts
Web Forms,
Data Files
XML
Java Objects
.TXT
Federation
Engine
DB DB
Many ways to get data into the system:
Labmatrix
Framework

13. Now that you have:
•Collected… ()
•Standardized… (Not yet? Use built-in data cleaning tools)
•Normalized… (Not yet? Use built-in formula calculation tools)
…some, or all of your project data, how do you best
make use of them?

14. 14
ExplorationAcquisition AnalysisAnalysis
Typical Scientific Data Workflow
1. Data Acquisition
• Excel, Access, homebrews
• (Electronic?!) forms, notes
• LIMS & instruments output
• Labmatrix forms & records
• Other enterprise resources
• Etc…
2. Data Exploration
3.Data Analysis
• SAS, R
• Spotfire
• Tableau
• Statisticians
• Etc…
• Easy, graphical queries
• ETL & data cleaning tools
• Formulas & calculations
• Visualize charts & graphs

15. Cryptic DB you’ll never
have easy access to
Case Study: Common Problem in Translational Research

16. The Solution Qiagram: our award-winning “draw-your-question”
interface - SQL or programming training NOT required!
Just drag & drop, and run your query!

17. Qiagram: a visual data query tool
Example 1: “reporting & operational statistics” data query

18. Qiagram: a visual data query tool
Example 2: hypothesis-driven data exploration

19. Centralize Data: web-accessible system enables multi-site collaboration and
data collection, data/site management, data QA/review/reports, and immediate data
querying results; scalable, web browser client-server architecture
Encourage Standardization: increase & mandate data quality via
standardized (and customizable) data-entry interfaces, standardized vocabularies, and
standardized data models
Enforce User Roles & Permissions: flexible configurations of how
different users/groups/TAs can access specific data sets in collaborative settings
Maintain Security & Compliance: transmit data securely, facilitate
regulatory compliance, and track all data changes via detailed audit logs in this
HIPAA/PHI-compliant system; customizable data backup & recovery plans
Integration & Interoperability: multiple interfaces to communicate with
other data systems in your IT infrastructure; vocabulary & ontology definitions
KEY FRAMEWORK FEATURES