This is the PowerPoint version of the Video created by Dr Sanjoy Sanyal, Professor and Course Director of Neuroscience. The components of Basal Forebrain are described, followed by the Meso-limbic and Meso-cortical Pathways. Then their role in Drug Addiction and Schizophrenia are explained. Finally the Hypothalamic, Hippocampal Formation, Septal Areas and Amygdala Connections are demonstrated graphically. YouTube video has been embedded after Slide number 13, which contains a running commentary by the author on a formalinized juman brain specimen. It describes what has bee mentioned in the preceding slides. This is purely for educational purposes and no copyright infringement is intended. Tags: Basal Forebrain, Mesolimbic, Mesocortical, Drug Addiction, Schizophrenia, NAc Pathway, Hippocampal Formation, Septal Areas, Amygdala, Sanjoy Sanyal, Professor, Neuroscience,

1. Dr Sanjoy Sanyal
Professor and Course Director,
Neuroscience

2. Basal Forebrain Components
 OF-PFC: Orbito-Frontal Pre-Frontal Cortex
 Septal Areas:
 Cortical Areas: Para-terminal Gyrus (Adjacent to
Lamina Terminalis) and Sub-callosal (Under
Rostrum of Corpus Callosum)
 Subcortical Nuclei: Between Septum Pellucidum
and Anterior Commissure (Lateral, Medial, Posterior
Nuclei)
 Ventral Striatum: Nucleus Accumbens +
Olfactory Tubercle (Cells of Calleja)
 Ventral Pallidum: Substantia Innominata;
Including Nucleus Basalis of Meynert
 Anterior Hypothalamus: Pre-Optic Area

3. Orbito-
Frontal
PFC

4. Septal Areas and Connections

5. Ventral
Striatum
Includes Nucleus
Accumbens under
Striatum (Fusion of
Head of Caudate
Nucleus with Putamen)
Also includes
Olfactory Tubercle
(Part of Allocortex
containing Cells of
Calleja in Anterior
Perforated Substance)

6. Nucleus Accumbens

7. VentralPallidum

8. Nucleus Basalis of
Meynert

9. Ventral Striato-pallidal
Tract
 Olfactory Cortex / OF-PFC / Hippocampus
 Ventral Striatum (Nucleus Accumbens +
Olfactory Tubercle)
 Ventral Pallidum (Substantia innominata, which
includes Nucleus Basalis of Meynert)
 Dorso-medial (Medio-Dorsal) Nucleus of
Thalamus

10. Septal Areas and Connections

11. Meso-Limbic / Meso-Cortical
Tract

12. Meso-Limbic / Meso-Cortical
Tract

13. Schizophrenia and Reward
Pathway

14. Hypothalamic Afferents

15. Hypothalamic Efferents

16. Limbic Connections

18. Hippocampal
Formation
Connections

20. Amygdala Connections