This document discusses research on polyhydroxyalkanoates (PHAs) for tissue engineering. Previous studies produced only thin films or 3D scaffolds less than 2mm thick and did not identify an ideal concentration for fabricating thicker 3D scaffolds. The document compares methods for fabricating PHAs scaffolds and examines issues with residual porogens and their effects on cell growth media when using specific techniques like solvent casting and particulate leaching.