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Diagnostics Problems
Thymoma and Thymic Carcinoma:

Differences
Stages at presentation

Paraneoplastic syndromes in thymic carcinoma rarely
IHC differences:

EGFR more common in thymoma
C-kit more common in thymic carcinoma

Poorer prognosis of thymic carcinoma
Summary Thymic
Tumors
Thymoma and Thymic Carcinoma are unique entities
Both are sensitive to broad range of chemotherapeutic
agents
Anthracycline regimens associated with higher response
rates in Thymoma

In Stage III Disease, radiation improves PFS but not OS
We need to better identify the “targets” for targeted therapy
Always consider multidisciplinary aproach
The present study indicated that
appropriately selected patients
who underwent radical P/D had
lower perioperative morbidity
and mortality with similar, if not
superior, long-term survival
compared to EPP.
QUÉ HEMOS APRENDIDO EN EL
MUNDIAL 2013 de Mesoteliomas
Que existe un grupo de trabajo internacional muy
activo interesado en su diagnóstico y tratamiento
(IMIG)
Que las sesiones han sido muy ricas en contenido
y discusión

Que la prevención epidemiológica aún es posible
Que tenemos esperanza en drogas prometedoras

Que los pacientes se merecen nuestro esfuerzo
multidisciplinar
05 Mesotelioma pleural maligno y timoma

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05 Mesotelioma pleural maligno y timoma

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  • 3. Thymoma and Thymic Carcinoma: Differences Stages at presentation Paraneoplastic syndromes in thymic carcinoma rarely IHC differences: EGFR more common in thymoma C-kit more common in thymic carcinoma Poorer prognosis of thymic carcinoma
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  • 23. Summary Thymic Tumors Thymoma and Thymic Carcinoma are unique entities Both are sensitive to broad range of chemotherapeutic agents Anthracycline regimens associated with higher response rates in Thymoma In Stage III Disease, radiation improves PFS but not OS We need to better identify the “targets” for targeted therapy Always consider multidisciplinary aproach
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  • 44. The present study indicated that appropriately selected patients who underwent radical P/D had lower perioperative morbidity and mortality with similar, if not superior, long-term survival compared to EPP.
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  • 55. QUÉ HEMOS APRENDIDO EN EL MUNDIAL 2013 de Mesoteliomas Que existe un grupo de trabajo internacional muy activo interesado en su diagnóstico y tratamiento (IMIG) Que las sesiones han sido muy ricas en contenido y discusión Que la prevención epidemiológica aún es posible Que tenemos esperanza en drogas prometedoras Que los pacientes se merecen nuestro esfuerzo multidisciplinar