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9/16/15	
   1	
  
Electrochemical
pH
Ionic Strength
Biological
Mechanical Electrical
Magnetic
Light
Temperature
What is “SMART”?
External	
  
S+muli	
  
Internal	
  
S+muli	
  
9/16/15	
   2	
  
Increase stability and
promote an ordered
architecture
Decrease
extensive surface
functionalization
for eventual
degradation
Hard
Soft
Inorganic
Organic
Hybrid Materials
Hybrid Materials
Yang, X.; Moosa, B.; Deng, L.; Zhoa, L; Khashab, N. M. *
“Polymer Chemistry 2011, 2, 2543–2547.
Biomedical: pH-Triggered Micellar Membrane for
Controlled Release Microchips
!
0 5 10 15 20
0
10
20
30
40
50
b
time (h)
DOXrelease(wt%)
pH=4.0
pH=5.0
pH=6.0
pH=7.0
pH=8.0
pH=9.0
!
General Scheme
Assembly and Application
Deng, Lin; Wang, Guangchao; Ren, Jian; Zhang, Bei; Yan, Jingjing; Li, Wengang; Khashab, N. M. * RSC adv. 2012, 2,
12909–12914
Biomedical: Enzymatically Triggered System
Based on Hyaluronic Acid Micelles
General Scheme
Deng, Lin; Wang, Guangchao; Ren, Jian; Zhang, Bei; Yan, Jingjing; Li, Wengang; Khashab, N. M. * RSC adv. 2012, 2,
12909–12914.
Biomedical: Enzymatically Triggered System
Based on Hyaluronic Acid Micelles
Biomedical: Magnetically Triggered Theranostic Platform
for Remote Cancer Cells Therapy and Imaging
!
General Scheme
Zhang, W.; Deng, L.; Wang, G.; Guo, X.; Li, Q.; Zhang, J.; Khashab, N. M. * Part. Pat. Syst. Charact. 2014, 31, 985–993.
Biomedical: Magnetically Triggered Theranostic Platform
for Remote Cancer Cells Therapy and Imaging
!
Zhang, W.; Deng, L.; Wang, G.; Guo, X.; Li, Q.; Zhang, J.; Khashab, N. M. * Part. Pat. Syst. Charact. 2014, 31, 985–993.
Biomedical: Photo-Triggered Membrane Based on Inter-
particle Crosslinking for Decreasing Diffusion Rates
PHCA microspheres
EC membrane
IrradiationDrug Reservoir Drug Reservoir
Lower Efflux
Crosslinking
(A)
Membrane
PMMA device
Reservoir for
drug loading
(B)
(C1) (C3)(C2)
b
c
a
d
(A)
(B)
Song, L., Moosa, M., Li, W.; Khashab, N. M.* J. Mater. Chem. B 2015, 3, 1208–1216.
Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522)
.
Biomedical: Graphene Oxide-Wrapped Gold
Nanorods
General Scheme
!
“Two-Step” Raman Imaging-Guided Chemo-Photothermal Cancer Therapy
Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522)
Biomedical: Graphene Oxide-Wrapped Gold
Nanorods
!
Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522)
.
Biomedical: Graphene Oxide-Wrapped Gold
Nanorods
SERS mapping of Doxorubicin (a) and
Graphene oxide (b) on AuNRs, ratio of
Doxorubicin to graphene oxide (c), and
overlap image (d) in Hela cell
Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522)
.
Biomedical: Graphene Oxide-Wrapped Gold
Nanorods
Biomedical: Photoresponsive Bridged Silsesquioxane
Nanoparticles with Tunable Morphology
1hν	

laserH
+
+
+
+
+ +
+
+
++
+
-
-
-
- -
-
-
- -
- -
-
-
-
--
- -
- -
-
-
- -
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- -
-
-
-
-
- - -
-
-
Fatieiev, Y.; Croissant, J.; Julfakyan, K.; Deng, L.; Anjum, D.H.; Gurinov, A.; Khashab, N.M. Nanoscale 2015, DOI: 10.1039/
C5NR03065J
BS NPs
Hollow BS NPs
200 nm
100 nm
H
+
+
+
+
+ +
+
+
++
+
H
+
+
+
+
+ +
+
+
++
+
H2O
H2O
EtOH
Origin
Irradiated
Or
e
Irra
e
4.05 ppm
Irra
e
4.00
3.75
Irradiated
Or
e
4.00
3.75
O
+ − +
O
−
+
1hν	

laser
1hν	

laser
Positive Zeta potential Negative Zeta potential
Fatieiev, Y.; Croissant, J.; Julfakyan, K.; Deng, L.; Anjum, D.H.; Gurinov, A.; Khashab, N.M. Nanoscale 2015, DOI: 10.1039/
C5NR03065J
Hollow BS NPs
DNA
1hν	

laser
Zeta Potential (mV)	
ChargeDist.(a.u.)	
-100 -50 0 50 100	
-39 mV
+46 mV
1hν	

H
+
+
+
+
+ +
+
+
++
+
-
-
-
-
-
-
-
-
-
-
-
-
- -
--
-
-
-
- -
- - -
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- -
-
-
-
-
- - -
-
-
H
+
+
+
+
+ +
+
+
++
+
Fatieiev, Y.; Croissant, J.; Julfakyan, K.; Deng, L.; Anjum, D.H.; Gurinov, A.; Khashab, N.M. Nanoscale 2015, DOI: 10.1039/
C5NR03065J
Angew. Chem. Int. Ed. 2015, accepted DOI: 10.1002/anie.201501615R1 and 10.1002/ange.201501615R1 (Cover image, Highlighted
by Nature Middle East)
Biomedical: Light Triggered Colloidosomes
-
+
-
+
-+
-
+-+
-
+
-
+
-
+
- +
-
+ - +
-
+
-
-
-
-
--
-
---
-
-
-
-
-
-
- -
-
- - -
-
-
hv
Stable colloidosome
Unstable colloidosomeDissociation of colloidosome
NBSN-2
NBSN-1
-
+
+
- -+
-+
+
-
+ -
-
+
+
-
+
Oil
phase Water
phase
Emulsion with two types of NPs
A
-
--
-
--
-
-
-
-
-
-
-
- -
--
-
- -
-
-
-
-
C
B
-100
-80
-60
-40
-20
0
20
40
60
80
100
Before Irradiation After Irradiation
SN
(control)
Zeta	
  Potential	
  (mV)
NBSN-1 NBSN-2 S
(c
hν	

Positive
Neutral
- -
+
NP- NP+NB+
SURFACE CHARGE OF NP- & NP+ NANOBUILDING BLOCKS
COMPATIBLE WITH THE COLLOIDOSOME ASSEMBLY/DISASSEMBLY
28	
  
Biomedical: Light Triggered Colloidosomes
3	
  µm 	
  500	
  nm
	
  500	
  nm
	
  	
  	
  	
  200	
  	
  nm	
   29	
  
hν	

	
  500	
  nm
ELECTROSTATIC DISASSEMBLY OF COLLOISOMES
UPON LASER IRRADIATION
30	
  
0	
  
20	
  
40	
  
60	
  
80	
  
100	
  
0	
   5	
   10	
   15	
   20	
  
Release	
  (%)
Time	
  (min)
Cargo loaded
Colloidosomes
OFF ON OFF ON
hν	

hν	

hν	

31	
  Angew. Chem. Int. Ed. 2015, accepted DOI: 10.1002/anie.201501615R1 and 10.1002/ange.201501615R1 (Cover image, Highlighted
by Nature Middle East)
Biomedical: AuNC@BSA Gated MSNs
+
+
+
+
+
+
+
+
Fluorescent
AuNC@BSAn-
Cargo3loaded
MSN3NH3
+
+
-
+
+
+
+
+
+
+
--
+
+
+
+
+
+
+
++
+
H+
pH 7.4
pH 5.0
Release9(%)
pH 5.0
pH 7.4
b
Time9(h)
a
!
a b
3 µm
c d
50 nm 50 nm
100 nm
!
Size%Distribution%(%)
Diameter%(nm)
2.5%nm
!
Biomedical: AuNC@BSA Gated MSNs
Cell	
  Viability	
  (%)
NPs	
  Concentration	
  (µg.mL-­‐1)
100
80
60
40
20
0
0	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  10	
  	
  	
  	
  	
  	
  	
  	
  	
  20	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  30	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  50	
  	
  	
  	
  	
  	
  	
  	
  	
  100	
  	
  	
  	
  	
  	
  	
  	
  150	
  	
  	
  	
   Cell$Viability$(%)
MSN$NH2+DOX
MSN$AuNC@BSA+DOX
DOX$Concentration$(µg.mL91) !
Biomedical: AuNC@BSA Gated MSNs
!
Absorption
Wavelength1(nm)
Emission
645$nm364$nm
496$nm
!
Biomedical: AuNC@BSA Gated MSNs
Red$Channel$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$Blue$Channel$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$Merged
Saline
Control
Hoe4loaded$
MSN4AuNC@BSA
a
b
!
Biomedical: AuNC@BSA Gated MSNs
S
L
T
K
Lu
Saline
Control
a Merged222222222222222222222222Red2Channel22222222222 Blue2Channel2 Red+Blue2Channel22222222
L
T
K
Lu
b
Hoe9loaded2
MSN9AuNC@BSA
!
Submitted
Biomedical: AuNC@BSA Gated MSNs
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Xie, J.; Zheng, Y.; Ying, J. Y. J. Am. Chem. Soc., 2009, 131, 888
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
Sensitivity
Selectivity
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
Sensing: Protein-Directed Synthesis of Highly
Fluorescent Gold Nanoclusters
Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
Biomedical: Zippered Release from Polymer
Gated Carbon Nanotubes
!
Mashat, A.; Deng, L; Altawashi, A.; Sougrat, R.; Wang, G.; Khashab, N. M. * “Zippered Release from Polymer Gated
Carbon Nanotubes” J. Mater. Chem. 2012, 22, 11503–11508.
General Scheme
Biomedical: Zippered Release from Polymer
Gated Carbon Nanotubes
Mashat, A.; Deng, L; Altawashi, A.; Sougrat, R.; Wang, G.; Khashab, N. M. * “Zippered Release from Polymer Gated
Carbon Nanotubes” J. Mater. Chem. 2012, 22, 11503–11508.
!
Chen, Ye; Tao, Jing; Deng, Lin; Li, Liang; Li, Jun; Yang, Yang; Khashab, N. M.* ACS App. Mater. Inter. 2013, 5, 7478–
7484. .
Composites: PEI/Bucky Gels Nanocomposites
with Superior Conductivity and Thermal Stability
!
General Scheme
Chen, Ye; Tao, Jing; Deng, Lin; Li, Liang; Li, Jun; Yang, Yang; Khashab, N. M.* ACS App. Mater. Inter. 2013, 5, 7478–7484.
Composites: PEI/Bucky Gels Nanocomposites
with Superior Conductivity and Thermal Stability
!
Chen, Ye; Tao, Jing; Song, Li; Khashab, N. M. * ACS App. Mater. Inter. 2014, 6, 9013–9022.
Composites: Polyfluorene Wrapped Carbon
nanotubes for Enhanced Interfacial Interactions
General Scheme
Chen, Ye; Tao, Jing; Song, Li; Khashab, N. M. * ACS App. Mater. Inter. 2014, 6, 9013–9022.
Composites: Polyfluorene Wrapped Carbon
nanotubes for Enhanced Interfacial Interactions
Composites: Surface Modification of Multiwall Carbon
Nanotubes with Cationic Conjugated Polyelectrolytes
General Scheme
Ezzeddine, A.; Chen, Z.; Schanze, K. S.; Khashab, N. M. ACS Appl. Mater. Interfaces, 2015, 7 , 12903–12913.
Composites: Surface Modification of Multiwall Carbon
Nanotubes with Cationic Conjugated Polyelectrolytes
Ezzeddine, A.; Chen, Z.; Schanze, K. S.; Khashab, N. M. ACS Appl. Mater. Interfaces, 2015, 7 , 12903–12913.
KAUST	
  on	
  the	
  Red	
  Sea
Spring 2016 internships and graduate students
Applications
are now open for submission
http://visitingstudent.kaust.edu.sa/Pages/Home.aspx
Niveen.khashab@kaust.edu.sa

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Innovatival Functionalized Nanomaterials for Biomedicalm Sensing and Composites Applications

  • 1. 9/16/15   1   Electrochemical pH Ionic Strength Biological Mechanical Electrical Magnetic Light Temperature What is “SMART”? External   S+muli   Internal   S+muli  
  • 2. 9/16/15   2   Increase stability and promote an ordered architecture Decrease extensive surface functionalization for eventual degradation Hard Soft Inorganic Organic Hybrid Materials Hybrid Materials
  • 3. Yang, X.; Moosa, B.; Deng, L.; Zhoa, L; Khashab, N. M. * “Polymer Chemistry 2011, 2, 2543–2547. Biomedical: pH-Triggered Micellar Membrane for Controlled Release Microchips ! 0 5 10 15 20 0 10 20 30 40 50 b time (h) DOXrelease(wt%) pH=4.0 pH=5.0 pH=6.0 pH=7.0 pH=8.0 pH=9.0 ! General Scheme Assembly and Application
  • 4. Deng, Lin; Wang, Guangchao; Ren, Jian; Zhang, Bei; Yan, Jingjing; Li, Wengang; Khashab, N. M. * RSC adv. 2012, 2, 12909–12914 Biomedical: Enzymatically Triggered System Based on Hyaluronic Acid Micelles General Scheme
  • 5. Deng, Lin; Wang, Guangchao; Ren, Jian; Zhang, Bei; Yan, Jingjing; Li, Wengang; Khashab, N. M. * RSC adv. 2012, 2, 12909–12914. Biomedical: Enzymatically Triggered System Based on Hyaluronic Acid Micelles
  • 6. Biomedical: Magnetically Triggered Theranostic Platform for Remote Cancer Cells Therapy and Imaging ! General Scheme Zhang, W.; Deng, L.; Wang, G.; Guo, X.; Li, Q.; Zhang, J.; Khashab, N. M. * Part. Pat. Syst. Charact. 2014, 31, 985–993.
  • 7. Biomedical: Magnetically Triggered Theranostic Platform for Remote Cancer Cells Therapy and Imaging ! Zhang, W.; Deng, L.; Wang, G.; Guo, X.; Li, Q.; Zhang, J.; Khashab, N. M. * Part. Pat. Syst. Charact. 2014, 31, 985–993.
  • 8. Biomedical: Photo-Triggered Membrane Based on Inter- particle Crosslinking for Decreasing Diffusion Rates PHCA microspheres EC membrane IrradiationDrug Reservoir Drug Reservoir Lower Efflux Crosslinking (A) Membrane PMMA device Reservoir for drug loading (B) (C1) (C3)(C2) b c a d (A) (B) Song, L., Moosa, M., Li, W.; Khashab, N. M.* J. Mater. Chem. B 2015, 3, 1208–1216.
  • 9. Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522) . Biomedical: Graphene Oxide-Wrapped Gold Nanorods General Scheme ! “Two-Step” Raman Imaging-Guided Chemo-Photothermal Cancer Therapy
  • 10. Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522) Biomedical: Graphene Oxide-Wrapped Gold Nanorods !
  • 11. Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522) . Biomedical: Graphene Oxide-Wrapped Gold Nanorods SERS mapping of Doxorubicin (a) and Graphene oxide (b) on AuNRs, ratio of Doxorubicin to graphene oxide (c), and overlap image (d) in Hela cell
  • 12. Deng, L.; Li, Q.; Yang, Y.;Omar, H; Tang, N.; Zhang,J.; Nie, Z.; Khashab, N. M.* Chem. Eur. J. 2015, accepted (chem.201502522) . Biomedical: Graphene Oxide-Wrapped Gold Nanorods
  • 13. Biomedical: Photoresponsive Bridged Silsesquioxane Nanoparticles with Tunable Morphology 1hν laserH + + + + + + + + ++ + - - - - - - - - - - - - - - -- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Fatieiev, Y.; Croissant, J.; Julfakyan, K.; Deng, L.; Anjum, D.H.; Gurinov, A.; Khashab, N.M. Nanoscale 2015, DOI: 10.1039/ C5NR03065J
  • 14. BS NPs Hollow BS NPs 200 nm 100 nm H + + + + + + + + ++ + H + + + + + + + + ++ + H2O H2O EtOH
  • 15. Origin Irradiated Or e Irra e 4.05 ppm Irra e 4.00 3.75 Irradiated Or e 4.00 3.75 O + − + O − + 1hν laser 1hν laser Positive Zeta potential Negative Zeta potential Fatieiev, Y.; Croissant, J.; Julfakyan, K.; Deng, L.; Anjum, D.H.; Gurinov, A.; Khashab, N.M. Nanoscale 2015, DOI: 10.1039/ C5NR03065J
  • 16. Hollow BS NPs DNA 1hν laser Zeta Potential (mV) ChargeDist.(a.u.) -100 -50 0 50 100 -39 mV +46 mV 1hν H + + + + + + + + ++ + - - - - - - - - - - - - - - -- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - H + + + + + + + + ++ + Fatieiev, Y.; Croissant, J.; Julfakyan, K.; Deng, L.; Anjum, D.H.; Gurinov, A.; Khashab, N.M. Nanoscale 2015, DOI: 10.1039/ C5NR03065J
  • 17. Angew. Chem. Int. Ed. 2015, accepted DOI: 10.1002/anie.201501615R1 and 10.1002/ange.201501615R1 (Cover image, Highlighted by Nature Middle East) Biomedical: Light Triggered Colloidosomes - + - + -+ - +-+ - + - + - + - + - + - + - + - - - - -- - --- - - - - - - - - - - - - - - hv Stable colloidosome Unstable colloidosomeDissociation of colloidosome NBSN-2 NBSN-1 - + + - -+ -+ + - + - - + + - + Oil phase Water phase Emulsion with two types of NPs A - -- - -- - - - - - - - - - -- - - - - - - - C B
  • 18. -100 -80 -60 -40 -20 0 20 40 60 80 100 Before Irradiation After Irradiation SN (control) Zeta  Potential  (mV) NBSN-1 NBSN-2 S (c hν Positive Neutral - - + NP- NP+NB+ SURFACE CHARGE OF NP- & NP+ NANOBUILDING BLOCKS COMPATIBLE WITH THE COLLOIDOSOME ASSEMBLY/DISASSEMBLY 28   Biomedical: Light Triggered Colloidosomes
  • 19. 3  µm  500  nm  500  nm        200    nm   29  
  • 20. hν  500  nm ELECTROSTATIC DISASSEMBLY OF COLLOISOMES UPON LASER IRRADIATION 30  
  • 21. 0   20   40   60   80   100   0   5   10   15   20   Release  (%) Time  (min) Cargo loaded Colloidosomes OFF ON OFF ON hν hν hν 31  Angew. Chem. Int. Ed. 2015, accepted DOI: 10.1002/anie.201501615R1 and 10.1002/ange.201501615R1 (Cover image, Highlighted by Nature Middle East)
  • 22. Biomedical: AuNC@BSA Gated MSNs + + + + + + + + Fluorescent AuNC@BSAn- Cargo3loaded MSN3NH3 + + - + + + + + + + -- + + + + + + + ++ + H+ pH 7.4 pH 5.0 Release9(%) pH 5.0 pH 7.4 b Time9(h) a !
  • 23. a b 3 µm c d 50 nm 50 nm 100 nm ! Size%Distribution%(%) Diameter%(nm) 2.5%nm ! Biomedical: AuNC@BSA Gated MSNs
  • 24. Cell  Viability  (%) NPs  Concentration  (µg.mL-­‐1) 100 80 60 40 20 0 0                          10                  20                    30                    50                  100                150         Cell$Viability$(%) MSN$NH2+DOX MSN$AuNC@BSA+DOX DOX$Concentration$(µg.mL91) ! Biomedical: AuNC@BSA Gated MSNs
  • 27. S L T K Lu Saline Control a Merged222222222222222222222222Red2Channel22222222222 Blue2Channel2 Red+Blue2Channel22222222 L T K Lu b Hoe9loaded2 MSN9AuNC@BSA ! Submitted Biomedical: AuNC@BSA Gated MSNs
  • 28. Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Xie, J.; Zheng, Y.; Ying, J. Y. J. Am. Chem. Soc., 2009, 131, 888
  • 29. Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
  • 30. Sensitivity Selectivity Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
  • 31. Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
  • 32. Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
  • 33. Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
  • 34. Sensing: Protein-Directed Synthesis of Highly Fluorescent Gold Nanoclusters Hu, L.; Deng, L.; Alsaiari, S.; Zhang, D.; Khashab, N. M. Anal. Chem., 2014, 86, 4989–4994.
  • 35. Biomedical: Zippered Release from Polymer Gated Carbon Nanotubes ! Mashat, A.; Deng, L; Altawashi, A.; Sougrat, R.; Wang, G.; Khashab, N. M. * “Zippered Release from Polymer Gated Carbon Nanotubes” J. Mater. Chem. 2012, 22, 11503–11508. General Scheme
  • 36. Biomedical: Zippered Release from Polymer Gated Carbon Nanotubes Mashat, A.; Deng, L; Altawashi, A.; Sougrat, R.; Wang, G.; Khashab, N. M. * “Zippered Release from Polymer Gated Carbon Nanotubes” J. Mater. Chem. 2012, 22, 11503–11508. !
  • 37. Chen, Ye; Tao, Jing; Deng, Lin; Li, Liang; Li, Jun; Yang, Yang; Khashab, N. M.* ACS App. Mater. Inter. 2013, 5, 7478– 7484. . Composites: PEI/Bucky Gels Nanocomposites with Superior Conductivity and Thermal Stability ! General Scheme
  • 38. Chen, Ye; Tao, Jing; Deng, Lin; Li, Liang; Li, Jun; Yang, Yang; Khashab, N. M.* ACS App. Mater. Inter. 2013, 5, 7478–7484. Composites: PEI/Bucky Gels Nanocomposites with Superior Conductivity and Thermal Stability !
  • 39. Chen, Ye; Tao, Jing; Song, Li; Khashab, N. M. * ACS App. Mater. Inter. 2014, 6, 9013–9022. Composites: Polyfluorene Wrapped Carbon nanotubes for Enhanced Interfacial Interactions General Scheme
  • 40. Chen, Ye; Tao, Jing; Song, Li; Khashab, N. M. * ACS App. Mater. Inter. 2014, 6, 9013–9022. Composites: Polyfluorene Wrapped Carbon nanotubes for Enhanced Interfacial Interactions
  • 41. Composites: Surface Modification of Multiwall Carbon Nanotubes with Cationic Conjugated Polyelectrolytes General Scheme Ezzeddine, A.; Chen, Z.; Schanze, K. S.; Khashab, N. M. ACS Appl. Mater. Interfaces, 2015, 7 , 12903–12913.
  • 42. Composites: Surface Modification of Multiwall Carbon Nanotubes with Cationic Conjugated Polyelectrolytes Ezzeddine, A.; Chen, Z.; Schanze, K. S.; Khashab, N. M. ACS Appl. Mater. Interfaces, 2015, 7 , 12903–12913.
  • 43. KAUST  on  the  Red  Sea Spring 2016 internships and graduate students Applications are now open for submission http://visitingstudent.kaust.edu.sa/Pages/Home.aspx Niveen.khashab@kaust.edu.sa