This document provides information on how the human body changes with age and some factors that can affect longevity. It discusses how lifestyle choices like diet, exercise, meditation and nutrition can positively influence health and longevity. Genetics are also believed to play a role, but environmental factors may account for 75% of longevity differences between individuals. Maintaining physical and mental activity in older age is linked to living longer in centenarians studied.

1. WELCOME

2. AGING & It's AFFECTING FACTOR BY R.C.DOHARE B.E.(mech),PGDCSc,M.E.(E.S.E.)

3. Your amazing body Gas- On average, you will release 2 litres of gases from your intestines today as burps or farts. Hair- Hair grows about 0.5mm a day. Heartbeats- Your heart pumps 13,640 litres of blood around your body in a day – enough to fill nearly 40,000 drink cans. An average heart beat pumps 59cc of blood. An average heart beat rate of 70 beats a minute adds up to more than 100,000 beats a day. Blood- An adult man’s body contains about 5 litres of blood. A woman’s contains about 4.3 litres. The blood travels along 100,000 km of blood vessels, which is equal to going 2.5 times round the equator. It contains 25,000,000,000 to 30,000,000,000 red cells . The life span of red cells is only about 120 days, and 1,200,000 to 2,000,0000 of them are made every second. In a human life time you will make 0.5 tonne of red cells. Red cells are made and destroyed at a rate of 2-3 million per second.

6. Sleep – In 7.5 hours of sleep, you will sleep lightly for 60 percent of the time and deeply for 18 percent . You will dream for 20 percent of the time. Sweat – You lose about 0.5 litres of water a day through 3,000,000 sweat glands. In hot climates you may lose as much as 13.5 litres a day. Urine – You will pass between 400 and 2,000 milliliters of urine every day, depending on how old you are, your body size and the outside conditions, especially temperature. Chemicals – There is enough carbon in your body to fill 900 pencils, enough fat to make a 7.5cm nail. Digestive system – Your stomach produces up to 2 litres of hydrochloric acid a day. Stomach acid is strong enough to dissolve metals, but it does not have time to damage the stomach walls because 500,000 cells in your stomach lining are replaced every minute. The small intestine is about 5m long and is the longest part of your digestive system. The large intestine is a thicker tube, but is only about 1.5m long. Eyes – You blink about 20,000 times a day.

7. What’s your body made of ? 1 Silicon 140 Sulphur 2.3 Zinc 780 Phosphorus 4 Iron 1200 Calcium 25 Magnesium 1800 Nitrogen 95 Chlorine 7000 Hydrogen 100 Sodium 16000 Carbon 110-140 Potassium 43000 Oxygen Average in 70kg person (g) Elements Average in 70kg person (g) Elements

8. Largest human organs 315 265 Male Female Heart 580 510 Right Left Lungs 1408 1263 Male Female Brain 1560 Liver 4100 Skin Average weight (grams) Organ

9. 6 6 Left Right Adrenals 20 Male only Prostate 35 Thyroid 98 Pancreas 170 Spleen 150 140 Left Right Kidneys

10. What we eat in life time(80 ) 1,140 Poultry 1,444 Cakes and biscuits 1,851 Processed fruit and nuts 2,092 Cereals 2,113 Other fresh vegetables 2,775 Processed vegetables 2,991 Fresh potatoes 3,058 Alcoholic drinks 3,166 Fresh fruit 3,261 Bread 7,255 Soft drinks 8,969 Milk and cream Amount eaten (kg) Food/drink

12. 115 years and 228 days 115 years and 252 days 115 years and 319 days 116 years and 88 days 116 years and 175 days 117 years and 229 days 117 years and 229 days 117 years and 248 days 119 years and 248 days 122 years and 164 days Age UK Denmark/USA USA USA Japan USA Canada USA USA France Country Charlotte Hughes (1877-1993) Christan Mortensen (1882-1998) Maggie Barnes (1882-1998) Carrie white (1874-1991) Tane Ikai (1879-1995) Estella jones (1881-1999) Marie-Louise Meillur (1881-1999) Lucy Hannah (1875-1993) Sarah DeRemer Knauss (1880-1999) Jeanne Calment (1857-1997) Name/dates

14. Usually five women reach the century mark for every man who accomplishes that feat. Jean Calment, who died in 1997 at the age of 122. In 1900 the average life expectancy was 45 years. Japan had the highest average healthy life expectancy of 74.5 years. The U.S. placed 24th with 70.0 years.

22. After 30-35 years several systems of aging start making their appearance slowly. The Thymus gland which is responsible for protecting The body against invading foreign organism weighs about 200-250 grammas at birth. After maturityorganbegins to shrink and by the 60 th year reduced To a small size about 3-5 grammas.

27. . May flies – 1 day House flies – 30days Rat – 3years Dogs – 12 years Horses – 25 years Elephant – 65 years Man – 70years

30. THE LONGEVITY PUZZLE The mutations seem to make cells less responsive than normal to insulin like growth factor 1 (IGF1), a key growth hormone secreted by the liver. In past studies, IGF1 disruption increased the life span of mice by 30 to 40 percent and delayed the onset of age-related diseases in the animals. The finding suggests that the IGF1R mutations confer added "susceptibility" to longevity, perhaps in concert with other genetic variants, the research team reports in Proceedings of the National Academy of Sciences

33. Eat (Less) to Live (Longer)

42. that remain on this diet not only live longer but are far healthier during their prolonged lives. Most diseases, including cancer, diabetes and even neurodegenerative illnesses, are forestalled. The organism seems to be supercharged for survival. The only apparent trade-off in some creatures is a loss of fertility.

46. set the pace of aging in the entire organism and make Sirt1 a key regulator of the longevity conferred by calorie restriction in mammals. It would also closely link aging and metabolic diseases, including type 2 diabetes, associated with excess fat. Intervening pharmacologically in the Sirt1 pathway in fat cells might therefore forestall not only aging but also specific ailments

67. FRESH FRUETS

69. MAIZE

70. BROCCLI

71. NUTS

73. BANANA

74. BLUE BERRIES

75. BOILED EGGS

76. LETEUS LEAVES

77. SEAFOOD

78. GARLIC

79. GINSENG

80. HONEY

81. JOGGING

82. ORGANIC CARRETS