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Prathamesh V. Kolekar
Dept. Instrumentation Engg.
Vishwakarma Institute of Technology,
Pune.
 INTRODUCTION
 NANOSENSOR TECHNOLOGY
 TYPES
 APPLICATIONS
 FUTURE CHALLENGES
SENSOR
•SENSES
ACTION
TRANSDUCER
•CONVERTS
I/P TO
ELECTRIC
SIGNAL
DETECTOR
•DETECTS
CHANGE
OCCURED
WHAT IS NANO SENSOR ?
N...
 Sensors operating on the scale of atoms
and molecules
 Smaller size, lower weight, modest power
requirements
 Data sto...
 PHYSICAL SENSORS
 CHEMICAL SENSORS
 BIOSENSORS
i. Bio receptors
ii. Transducers
iii. Detectors
 CANTILEVER ARRAY SENSORS
 NANOTUBE SENSORS
 NANOWIRE SENSORS
 CANTILEVER ARRAY SENSOR
 WORKING
BIO
CHEMICAL/PHYSIC
AL PROCESS
MICRO ELECRO
MECHANICAL
SYSTEM
 PRECISSION CANTILEVERS: 300 nm THICKNESS TOLERANCE
 PRECISSION RESONANCE FREQUENCY: SPECIAL CANTILEVER
MOUNT
 EASY HAN...
 SIZE / SHAPE
RECTANGULAR SHAPED SILICON BARS
DUOSENSIS SENSORS (2 CANTILEVERS PER CHIP)
OCTOSENSIS SENSORS (8 CANTILEVER...
 FOR DIAGNOSIS OF DIABETES MELLITUS
Small amounts of acetone in a patient’s breath can be detected by cantilever
array se...
 FOR CANCER DIAGNOSIS
When the cancer-associated molecules bind to the cantilevers, changes in
surface tension cause the ...
 NANOTUBE SENSOR
 SIZE / SHAPE
coated with strands of DNA
could detect molecules on the order of one
part per million
 PLATFORM
The Nano sensors could sniff molecules out of the air or
taste them in a liquid, suggesting applications rangin...
 FOR BLOOD GLUCOSE MONITARING
ENZYME GLUCOSE OXIDASE IS NON-COVALENTLY ATTACHED
BRINGS CATALYSATION OF GLUCOSE YIELDING H...
 NANO WIRE SENSOR
 STRUCTURE
DNA(DETECTOR)
NANOTUBE(TRANSMITTER)
SINGLE
STRANDED
DNA
CARBON
NANOTUBE
NANOWIRE
 DETECTION OF SINGLE VIRUS
NANOWIRES CONFIGURED AS A FET
DETECTION OF SINGLE VIRUS ON RECEPTORS CHANGES
CONDUCTANCE
NANOS...
 DETECTION OF BIOMOLECULE
SILICON NANOWIRE USED FOR
DETECTION OF PROTEIN KINASE VIZ CAUSE OF CHRONIC
LEUKEMIA
SILICON Nano sensor WITH PEPTIDE NUCLE...
 TO IMPROVE SENSITIVITY OF CANTILEVER Nano sensor
 UNWANTED BIOFOULING (DETECTION OF NON-ADSORBING
MOLECULE)
 USUAL DES...
Nano sensors with their applications
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Nano sensors with their applications

  1. 1. Prathamesh V. Kolekar Dept. Instrumentation Engg. Vishwakarma Institute of Technology, Pune.
  2. 2.  INTRODUCTION  NANOSENSOR TECHNOLOGY  TYPES  APPLICATIONS  FUTURE CHALLENGES
  3. 3. SENSOR •SENSES ACTION TRANSDUCER •CONVERTS I/P TO ELECTRIC SIGNAL DETECTOR •DETECTS CHANGE OCCURED WHAT IS NANO SENSOR ? NANO+SENSOR
  4. 4.  Sensors operating on the scale of atoms and molecules  Smaller size, lower weight, modest power requirements  Data storage systems
  5. 5.  PHYSICAL SENSORS  CHEMICAL SENSORS  BIOSENSORS i. Bio receptors ii. Transducers iii. Detectors
  6. 6.  CANTILEVER ARRAY SENSORS  NANOTUBE SENSORS  NANOWIRE SENSORS
  7. 7.  CANTILEVER ARRAY SENSOR
  8. 8.  WORKING BIO CHEMICAL/PHYSIC AL PROCESS MICRO ELECRO MECHANICAL SYSTEM
  9. 9.  PRECISSION CANTILEVERS: 300 nm THICKNESS TOLERANCE  PRECISSION RESONANCE FREQUENCY: SPECIAL CANTILEVER MOUNT  EASY HANDLING: VERTICAL CHIP SIDEWALLS, OPTIONAL NON STICKING  CONTAMINATION FREE STORAGE
  10. 10.  SIZE / SHAPE RECTANGULAR SHAPED SILICON BARS DUOSENSIS SENSORS (2 CANTILEVERS PER CHIP) OCTOSENSIS SENSORS (8 CANTILEVERS PER CHIP)
  11. 11.  FOR DIAGNOSIS OF DIABETES MELLITUS Small amounts of acetone in a patient’s breath can be detected by cantilever array sensor technique which may attribute to early diagnosis of diabetes mellitus.  FOR DETECTION OF BACTERIAS,FUNGI,VIRUSES antigens on cell membrane surface results in additional mass loading, ultra- sensitively detected by the device using nanochemical oscillator The detection sensitivity is in the order of a single bacterium corresponding to a mass of ~1 pg
  12. 12.  FOR CANCER DIAGNOSIS When the cancer-associated molecules bind to the cantilevers, changes in surface tension cause the cantilever to bend The mass detection limitation of NEMS cantilevers is improved to the enumeration of a single DNA molecule consisting of ~1600 base pairs and weighing ~1 ag (atto = 10^18).
  13. 13.  NANOTUBE SENSOR
  14. 14.  SIZE / SHAPE coated with strands of DNA could detect molecules on the order of one part per million
  15. 15.  PLATFORM The Nano sensors could sniff molecules out of the air or taste them in a liquid, suggesting applications ranging from domestic security to medical detectors.
  16. 16.  FOR BLOOD GLUCOSE MONITARING ENZYME GLUCOSE OXIDASE IS NON-COVALENTLY ATTACHED BRINGS CATALYSATION OF GLUCOSE YIELDING HYDROGEN- PEROXIDE ENZYME IMMOBILISATION ALLOWS FLOW OF CURRENT
  17. 17.  NANO WIRE SENSOR
  18. 18.  STRUCTURE DNA(DETECTOR) NANOTUBE(TRANSMITTER) SINGLE STRANDED DNA CARBON NANOTUBE NANOWIRE
  19. 19.  DETECTION OF SINGLE VIRUS NANOWIRES CONFIGURED AS A FET DETECTION OF SINGLE VIRUS ON RECEPTORS CHANGES CONDUCTANCE NANOSIZED WIRE REQUIRED FOR HIGH SIGNAL TO NOISE RATIO
  20. 20.  DETECTION OF BIOMOLECULE
  21. 21. SILICON NANOWIRE USED FOR DETECTION OF PROTEIN KINASE VIZ CAUSE OF CHRONIC LEUKEMIA SILICON Nano sensor WITH PEPTIDE NUCLEIC ACID DISTINGUISHES BETWEEN THESE MOLECULES
  22. 22.  TO IMPROVE SENSITIVITY OF CANTILEVER Nano sensor  UNWANTED BIOFOULING (DETECTION OF NON-ADSORBING MOLECULE)  USUAL DESIGN PROBLEMS  FLOW CONTROL  RISK AND ECONOMICS
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