1. DIAGNOSIS OF GENETIC DISORDERS & INFECTIOUS DISEASES Presentation by S.Prasanth Kumar

3. AUTOSOMAL DOMINANT Scenario

5. MOLECULAR BIOLOGY

6. Pathway

7. A microscope image of a neuron with inclusion (stained orange) caused by HD, Chemical structure of tetrabenazine DIAGNOSIS Psychological Examination CT, MRI Genetic Testing Neuroleptics , Benzodiazepines, Amantadine or Remacemide

8. AUTOSOMAL RECESSIVE Scenario

9. Niemann–Pick disease

11. D I A G N O S I S Organ transplant Enzyme Replacement Gene Therapy CYCLO (2-hydroxypropyl-β-cyclodextrin or HPBCD )

12. X-Linked Dominance SCENARIO

13. Incontinentia pigmenti

14. MOLECULAR BIOLOGY

15. DIAGNOSIS Collaborative Skin Biopsy Genetic Counseling, Prenatal Testing, Preimplantation Genetic Diagnosis

16. X- linked Recessive SCENARIO

17. Color Blindness

18. Rainbow Color

19. No color deficiencies Protanopia Deuteranopia Tritanopia

20. DIAGNOSIS Ishihara color test "74" Normal color vision. “ 21“ Dichromacy or Anomalous Trichromacy Not See Numbers Achromatopsia

21. Y- linkage No Interchromosomal Genetic Recombination

22. Male Infertility

24. DIAGNOSIS Semen Analysis Genetic Counselling Encouraged for IVF

26. Miliary tuberculosis

27. Miliary tuberculosis is characterized by a chronic, contagious bacterial infection caused by Mycobacterium tuberculosis that has spread to other organs of the body by the blood or lymph system.

28. Tests include chest x-ray, sputum culture,bronchoscopy,TB skin test, open lung biopsy, head CT/MRI, blood cultures, and electrocardiography Isoniazid and Rifampicin for six months, Ethambutol and Pyrazinamide for the first two months DIAGNOSIS

31. DIAGNOSIS FeLV blood tests Enzyme-linked immunosorbent assay (ELISA) Immunotluorescence assay (IFA) Both tests detect the p27 protein of FeLV as it circulates in the bloodstream, either free in the blood (ELISA test) or within infected white blood cells (IFA test).

32. FOR YOUR ATTENTION