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Bioinformatics

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Bioinformatics: Applications ZOO 5903/4903 Fall 2006, MW 10:30-11:45 Sutton Hall, Room 312 Jonathan D. Wren, Ph.D.
Prereqs ,[object Object],[object Object],[object Object]
Goals for this course ,[object Object],[object Object],[object Object],[object Object],[object Object]
Overview ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Textbook Plus, there will be supplementary reading assignments, usually online, and a few extra (suggested) readings
General policy/philosophy ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[email_address]
Strategic overview Instruction set  Active programs  Product  System  Network
Outline for 1 st exam classes (DNA thread)‏ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What is Bioinformatics? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The “old” biology The most challenging task for a scientist is to get good data
The “new” biology The most challenging task for a scientist is to make sense of lots of data
Old vs New - What’s the difference? 1) Economics ,[object Object],[object Object],[object Object],[object Object],[object Object]
What’s the difference? 2) Scale ,[object Object],[object Object],[object Object],[object Object]
What’s the difference? 3) Logic ,[object Object],[object Object],[object Object],[object Object],[object Object]
Data-driven Science Done Wrong ,[object Object],[object Object],[object Object],[object Object]
Data is being collected faster and in greater amounts
 
Growth in information & knowledge >4,800 Journals >16,000,000 records 672,000 new papers in 2005 (~1,840 per day)‏ MEDLINE spans:
The use of software & algorithms is becoming more common in biomedical research
Bio informatics
The use of bioinformatics and rate of growth is field-dependant
Data => Information => Knowledge ,[object Object],[object Object]
Data => Information => Knowledge ,[object Object],[object Object],[object Object],[object Object],Gene X is correlated with disease Y
Data => Information => Knowledge ,[object Object],[object Object],[object Object],[object Object],Gene X is correlated with disease Y Gene X homozygotes have severe disease Gene X is probably causal in disease Y
Bioinformatics – what can it do for you? ,[object Object],[object Object],[object Object]
 
 
For next time ,[object Object],[object Object]

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