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HIV and AIDS
HIV and AIDS HIV: Human Immunodeficiency Virus
HIV and AIDS AIDS: Acquired Immune Deficiency Syndrome  OR Acquired Immunodeficiency Syndrome
HIV and AIDS:  MYTHS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],TRUE FALSE
HIV and AIDS
[object Object],[object Object],[object Object],HIV and AIDS
HIV and AIDS Peripheral Fat Wasting (lipodystrophy)
Central Dogma DNA    RNA    Protein ,[object Object],[object Object],[object Object],[object Object],[object Object],HIV and AIDS
Transcription HIV and AIDS Copying DNA into RNA Reverse Transcription? Copying RNA into DNA
HIV: A retrovirus Receptors: CD4 molecules Coreceptors: fusin, CCR5 HIV and AIDS
Retroviruses (RNA Virus) Retroviruses have an enzyme (called reverse transcriptase) that is capable of  reverse transcribing their RNA into DNA .  This viral DNA can then be integrated into the host cell’s genome. HIV and AIDS
[object Object],[object Object],[object Object],[object Object],Retroviruses (RNA Virus) HIV and AIDS
[object Object],Retroviruses (RNA Virus) HIV and AIDS
[object Object],Retroviruses (RNA Virus) HIV and AIDS
[object Object],Retroviruses (RNA Virus) HIV and AIDS http://www.youtube.com/watch?v=dn1tNIrMPRk&feature=related
Retroviruses (RNA Virus) Retroviruses replicate with a high mutation rate, because reverse transcriptase  makes several errors! This increases it’s ability to evolve and survive. HIV and AIDS Some mutations will change the virus’ “appearance” and make it unrecognizable to the immune system
T-Cells ,[object Object],[object Object],[object Object],[object Object],HIV and AIDS
Pathology of HIV ,[object Object],[object Object],[object Object],Campbell Fig. 43.19 HIV and AIDS
HIV targets helper T-Cells ,[object Object],HIV and AIDS
HIV targets helper T-Cells HIV and AIDS
HIV and AIDS Helper T-cells are essential to the immune system HIV infects helper T-cells Therefore  HIV stops the immune system from working
Helper T-cells are essential to the immune system HIV and AIDS HIV Destroy foreign cells Kill infected cells
HIV treatment  http://www.youtube.com/watch?v=mzfnxCEsck4  HIV and AIDS
http://www.youtube.com/watch?v=eS1GODinO8w
How HIV is spread ,[object Object],[object Object],[object Object],[object Object],HIV and AIDS
How HIV is spread HIV and AIDS
How vaccines work   http://www.youtube.com/watch?v=C061bmvk7Hw HIV and AIDS
Challenges with AIDS vaccines ,[object Object],[object Object],[object Object],HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS
Retroviruses (RNA Virus) HIV and AIDS

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08 hiv and aids[1]

Notas do Editor

  1. http://www.aidsactioncoalition.org/images/hiv_virus.gif http://www.rhodes.edu/biology/glindquester/viruses/pagespass/hiv/retrovirus.jpg
  2. http://www.aidsactioncoalition.org/images/hiv_virus.gif http://www.rhodes.edu/biology/glindquester/viruses/pagespass/hiv/retrovirus.jpg
  3. http://www.lib.uiowa.edu/hardin/md/cdc/6058.html http://www.geradts.com/anil/ij///vol_003_no_002/reviews/tb/page001.html
  4. http://www.aidsactioncoalition.org/images/hiv_virus.gif http://www.rhodes.edu/biology/glindquester/viruses/pagespass/hiv/retrovirus.jpg
  5. http://www.youtube.com/watch?v=dn1tNIrMPRk&feature=related
  6. Campbell text: Figure 43.20
  7. Campbell text: Figure 43.20