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HYPERTENSION
Measurement of Blood Pressure
Mohammad Ilyas, M.D.
Assistant Clinical Professor
University of Florida / Health Sciences Center
Jacksonville, Florida USA
6/30/2014
1
Outline
1. Definition, Regulation and Pathophysiology
2. Measurement of Blood Pressure, Staging of Hypertension and Ambulatory
Blood Pressure Monitoring
3. Evaluation of Primary Versus Secondary
4. Sequel of Hypertension and Hypertension Emergencies
5. Management of Hypertension (Non-Pharmacology versus Drug Therapy)
6. The Relation Between Hypertension: Obesity, Drugs, Stress and Sleep
Disorders.
7. Hypertension in Renal diseases and Pregnancies
8. Pediatric, Neonatal and Genetic Hypertension
6/30/2014
2
History of Blood Pressure Measurement
Stephen Hales 1733
Hollow glass tube in neck
artery of horse
Blood rose 9 feet in glass tube
Medicine, an Illustrated History 1987
6/30/2014
3
History of Blood Pressure Measurement
 1896. Scipione Riva-Rocci
 Only Systolic BP measured
by palpation
Medicine, an Illustrated History 1987
6/30/2014
4
Measurement of Blood Pressure
Correct measurement and interpretation of the blood
pressure (BP) is essential in the diagnosis and management
of hypertension.
 It is essential that BP machines are properly calibrated,
 appropriate cuff sizes are selected, and,
 when BP is measured in an office-based setting
personnel are properly trained and
the patient is positioned correctly.
6/30/2014
5
Measuring accurate BP’s
Cuff too small → falsely high reading
Cuff too big → OK reading or no reading
(usually not falsely low)
Lower extremities - Normally, BP is 10 to 20
mmHg higher in the legs than the arms
Prefer arm if at all possible
Right arm for comparison with standards
6/30/2014
6
Blood Pressure Cuff size
• Bladder width >
40% of mid-arm
circumference.
• Bladder length
80-100% of arm
circumference.
6/30/2014
7
Blood Pressure Cuff Size
Index line
Bladder length (80%) 20%
Largest allowable mid arm
circumference for bladder (100%)
MAC = Mid Arm Circumference
Cuff length = 80% of MAC
Cuff width = 40% of MACMAC
6/30/2014
8
Confirming High BP’s
Repeat BP in both arms and one leg (both
not usually necessary)
Repeat 3 times to assure accurate
Dx of HTN requires elevated BP’s on 3
separate occasions
6/30/2014
9
Disappearance of “HTN” with
Repeated Measurement
6/30/2014
10
METHODS FOR THE DIAGNOSIS OF
HYPERTENSION
Hypertension can be diagnosed using one of the
following three acceptable measurement
strategies:
 Office-based blood pressure measurements
 Home blood pressure monitoring
 Ambulatory blood pressure monitoring (ABPM)
6/30/2014
11
Effect of Training on Observer Errors
Bruce NG et al. J Hypertens 1988; 6:375- 380
6/30/2014
12
New Blood Pressure Norms
OPTIMAL
<120 and <80
HIGH NORMAL
130-139 or 85-89
STAGE 1
140-159 or 90-99
STAGE 2
160-179 or 100-109
STAGE 3
≥180 or ≥110
NORMAL
<130 and <85
NORMAL
<120 and <80
PRE-HYPERTENSION
120-139 OR 80-89
STAGE 2
≥160 or ≥100
STAGE 1
140-159 or 90-99
JNC 7 (2003) JNC 8 (2013)JNC 6 (1997)
Hypertension
JNC VI. Arch Intern Med. 1997;157:2413-2446
JNC 7. JAMA. 2003;289(19):2560-2572.
6/30/2014
13
New Blood Pressure Norms for Children
Normotensive
Average SBP and DBP <90th % for age, sex and
height
Pre-hypertension
Average SBP or DBP >90th but <95th percentile
(OR >120/80)
Hypertension
Average SBP and/or DBP >95th percentile for
age, sex and height on 3 separate occasions
Stage 1: 95th-99th percentile + 5 mmHg
Stage 2: >99th percentile + 5 mm Hg
6/30/2014
14
How to use the percentile tables?
Need:
Age, gender, height percentage
BP charts
6/30/2014
15
7 yo boy
Ht 75%tile
http://www.cc.nih.gov/ccc/pedweb/pedsstaff/bptable1.PDF
50% 99/58
90% 113/73
95% 119/80
99% 127/88
6/30/2014
16
BP tables for Infants
*Task Force on Blood Pressure Control in Children. Report of the Second Task Force on Blood Pressure Control in Children—1987.Pediatrics.1987;79:1–25(PR)
6/30/2014
17
Devices
6/30/2014
18
DINAMAP
Oscillometric wrist BP monitor
Ambulatory BP monitor
Mercury sphygmanometer
Aneroid BP monitor
6/30/2014
19
Which blood pressure apparatus is the “Gold standard”
for BP measurement in children above age 3?
A. DINAMAP
B. Oscillometric wrist BP monitor
C. Ambulatory BP monitor
D. Mercury sphygmanometer
E. Aneroid BP monitor
6/30/2014
20
Mercury Sphygmomanometer
6/30/2014
21
Mercury Sphygmomanometry
1998: EPA and the American Hospital
Association agreed to virtually eliminate
mercury from hospitals by 2005
6/30/2014
22
Aneroid Manometer
Mercury pressure gauge
replaced by mechanical
spring
Gauges are often small
Accuracy varies among
manufacturers
Requires frequent calibration
6/30/2014
23
Aneroid Manometers
6/30/2014
24
Mercury and Aneroid Manometer
6/30/2014
25
Testing the Aneroid Manometer
 Does the needle rest at zero?
 Inflate to 200 mm Hg. Wait for 1
minute, if lower than 170 suspect
leak
 Using the Y connector, connect
to mercury device and check
readings
 If any reading is off by >4 mm,
remove from service
 Date the calibration
6/30/2014
26
Oscillometric Devices
Office Use
Expensive (approximately $3000)
Many have been validated (BHS, AAMI)
Recommended for children of all ages
Home Use
Relatively inexpensive
Few have been validated in children
Not recommended for ages < 4 years
6/30/2014
27
Oscillometric Devices
Measure mean arterial pressure (MAP)
and calculates SBP and DBP
The algorithms used are proprietary and NOT
standardized
Results can vary widely and they do not
always closely match BP values obtained by
auscultation
These machines must be calibrated regularly
6/30/2014
28
Dinamap®
Oscillometric Device
Dinamap®
is an
acronym for:
Device for
Indirect
Noninvasive
Mean
Arterial
Pressure
6/30/2014
29
Manual vs. Automatic
Manual is the gold standard
Oscillometric measurements preferred in infants
and ICU settings ONLY
All high readings should be confirmed with a
manual
6/30/2014
30
Oscillometric Devices
6/30/2014
31
What is being measured?
Auscultatory method: relies on relationship
between audible Korotkoff sounds and pressure
at systole and diastole
Oscillometric method: relies on the amplitude of
oscillations in the arterial wall to determine MAP
(maximum amplitude); complex and proprietary
algorithms used to estimate SBP and DBP
Mean arterial pressure (MAP) is average pressure
throughout the cardiac cycle.
MAP=(SBP)+2(DBP)/3
6/30/2014
32
Ambulatory BP Monitoring
Oscillometric or acoustic methods
24 hour monitoring
Individual measurements not
more accurate
Readings downloaded into PC
Cost: $2500-4500
6/30/2014
33
Ambulatory Blood Pressure Monitoring
6/30/2014
34
White Coat Hypertension
6/30/2014
35
Ambulatory Blood Pressure Monitoring
6/30/2014
36
Blood pressure is measured in preferably
on ?
A. Right lower leg
B. Left upper arm
C. Right upper arm
D. Left wrist
E. Right wrist
6/30/2014
37
Auscultatory Method
Sitting quietly for 5 minutes
Back supported and feet on the floor
Right arm supported, cubital fossa at
heart level
Estimate systolic BP by palpation, re-inflate
cuff to 20 mmHg higher
6/30/2014
38
What is the optimal rate of deflation of
blood pressure cuff?
A. 1 mm Hg/sec
B. 2-3 mm Hg/sec
C. 5 mm Hg/sec
D. 10 mm Hg/sec
6/30/2014
39
Auscultatory Method
Deflate cuff at 2-3 mmHg/sec
Systolic BP= onset tapping sounds*
Diastolic BP= disappearance of sounds (fifth
Korotkoff sound)
Record BP twice on each occasion as right arm,
sitting, SBP/DBP(K5), average used to estimate
BP level
6/30/2014
40
Characteristics of Korotkoff sounds.
6/30/2014
41
Auscultatory Method
DBP is determined by disappearance of
Krotkoff sounds (K5)
Sometime Krotkoff sounds heard till 0 mm Hg
Try less pressure on the head of stethoscope
If K5 still persists K4 should be recorded as DBP
6/30/2014
42
Fourth report on BP. Pediatrics August 2004
Summary
Accurate blood pressure measurement is the
corner stone of diagnosis of hypertension
Oscillatory method can be used for screening but
elevated blood pressure should be confirmed with
auscultatoy method
Appropriately sized cuff is mandatory and measure
mid arm circumference to choose the cuff size
Calibrate BP measurement apparatus semiannually
6/30/2014
43
Quizzes
6/30/2014
44
Quiz 1. When Measuring the Blood Pressure
all statement below are true EXCEPT
A. Correct measurement of the blood pressure (BP) is
essential in the diagnosis and management of
hypertension.
B. It is essential that BP machines are properly calibrated.
C. Appropriate cuff sizes are needed for children
D. When BP is measured in an office-based setting,
personnel training does not interfere the measurement.
E. The position of patient impact the BP readings.
6/30/2014
45
Quiz 1. When Measuring the Blood Pressure
all statement below are true EXCEPT
A. Correct measurement of the blood pressure (BP) is
essential in the diagnosis and management of
hypertension.
B. It is essential that BP machines are properly calibrated.
C. Appropriate cuff sizes are needed for children
D. When BP is measured in an office-based setting,
personnel training does not interfere the measurement.
E. The position of patient impact the BP readings.
6/30/2014
46
Quiz 2. All statements below are true,
EXCEPT
A. Cuff too small lead to falsely high BP reading
B. Cuff too big usually not lead to falsely low BP
reading
C. Lower extremities BP reading is 10 to 20 mmHg
lower than the arms
D. Right arm is the prefer arm if at all possible
E. Right arm for comparison with standards
6/30/2014
47
Quiz 2. All statements below are true,
EXCEPT
A. Cuff too small lead to falsely high BP reading
B. Cuff too big usually not lead to falsely low BP
reading
C. Lower extremities BP reading is 10 to 20 mmHg
lower than the arms
D. Right arm is the prefer arm if at all possible
E. Right arm for comparison with standards
6/30/2014
48
Quiz 3. Which of the following Staging of
Hypertension is not TRUE ?
A. Normal Blood pressure is systolic <120 and
diastolic < 80
B. Pre hypertension include systolic 120-140 and
diastolic 80-90
C. Stage 1 hypertension is systolic > 150
D. Stage 1 hypertension is diastolic > 90
E. Stage 2 hypertension is Systolic > 160
6/30/2014
49
Quiz 3. Which of the following Staging of
Hypertension is not TRUE ?
A. Normal Blood pressure is systolic <120 and
diastolic < 80
B. Pre hypertension include systolic 120-140 and
diastolic 80-90
C. Stage 1 hypertension is systolic > 150
D. Stage 1 hypertension is diastolic > 90
E. Stage 2 hypertension is Systolic > 160
6/30/2014
50
QUIZ 4. What is being measured?
TRUE / FALSE
A. Auscultatory method relies on relationship between
audible Korotkoff sounds and pressure at systole and
diastole.
B. Oscillometric method relies on the amplitude of
oscillations in the arterial wall to determine MAP
(maximum amplitude).
C. Mean arterial pressure (MAP) is average pressure
throughout the cardiac cycle.
6/30/2014
51
QUIZ 4. What is being measured?
TRUE / FALSE
A. Auscultatory method relies on relationship between
audible Korotkoff sounds and pressure at systole and
diastole. TRUE
B. Oscillometric method relies on the amplitude of
oscillations in the arterial wall to determine MAP
(maximum amplitude). TRUE
C. Mean arterial pressure (MAP) is average pressure
throughout the cardiac cycle. TRUE
6/30/2014
52

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Hypertension BP mesurement

  • 1. HYPERTENSION Measurement of Blood Pressure Mohammad Ilyas, M.D. Assistant Clinical Professor University of Florida / Health Sciences Center Jacksonville, Florida USA 6/30/2014 1
  • 2. Outline 1. Definition, Regulation and Pathophysiology 2. Measurement of Blood Pressure, Staging of Hypertension and Ambulatory Blood Pressure Monitoring 3. Evaluation of Primary Versus Secondary 4. Sequel of Hypertension and Hypertension Emergencies 5. Management of Hypertension (Non-Pharmacology versus Drug Therapy) 6. The Relation Between Hypertension: Obesity, Drugs, Stress and Sleep Disorders. 7. Hypertension in Renal diseases and Pregnancies 8. Pediatric, Neonatal and Genetic Hypertension 6/30/2014 2
  • 3. History of Blood Pressure Measurement Stephen Hales 1733 Hollow glass tube in neck artery of horse Blood rose 9 feet in glass tube Medicine, an Illustrated History 1987 6/30/2014 3
  • 4. History of Blood Pressure Measurement  1896. Scipione Riva-Rocci  Only Systolic BP measured by palpation Medicine, an Illustrated History 1987 6/30/2014 4
  • 5. Measurement of Blood Pressure Correct measurement and interpretation of the blood pressure (BP) is essential in the diagnosis and management of hypertension.  It is essential that BP machines are properly calibrated,  appropriate cuff sizes are selected, and,  when BP is measured in an office-based setting personnel are properly trained and the patient is positioned correctly. 6/30/2014 5
  • 6. Measuring accurate BP’s Cuff too small → falsely high reading Cuff too big → OK reading or no reading (usually not falsely low) Lower extremities - Normally, BP is 10 to 20 mmHg higher in the legs than the arms Prefer arm if at all possible Right arm for comparison with standards 6/30/2014 6
  • 7. Blood Pressure Cuff size • Bladder width > 40% of mid-arm circumference. • Bladder length 80-100% of arm circumference. 6/30/2014 7
  • 8. Blood Pressure Cuff Size Index line Bladder length (80%) 20% Largest allowable mid arm circumference for bladder (100%) MAC = Mid Arm Circumference Cuff length = 80% of MAC Cuff width = 40% of MACMAC 6/30/2014 8
  • 9. Confirming High BP’s Repeat BP in both arms and one leg (both not usually necessary) Repeat 3 times to assure accurate Dx of HTN requires elevated BP’s on 3 separate occasions 6/30/2014 9
  • 10. Disappearance of “HTN” with Repeated Measurement 6/30/2014 10
  • 11. METHODS FOR THE DIAGNOSIS OF HYPERTENSION Hypertension can be diagnosed using one of the following three acceptable measurement strategies:  Office-based blood pressure measurements  Home blood pressure monitoring  Ambulatory blood pressure monitoring (ABPM) 6/30/2014 11
  • 12. Effect of Training on Observer Errors Bruce NG et al. J Hypertens 1988; 6:375- 380 6/30/2014 12
  • 13. New Blood Pressure Norms OPTIMAL <120 and <80 HIGH NORMAL 130-139 or 85-89 STAGE 1 140-159 or 90-99 STAGE 2 160-179 or 100-109 STAGE 3 ≥180 or ≥110 NORMAL <130 and <85 NORMAL <120 and <80 PRE-HYPERTENSION 120-139 OR 80-89 STAGE 2 ≥160 or ≥100 STAGE 1 140-159 or 90-99 JNC 7 (2003) JNC 8 (2013)JNC 6 (1997) Hypertension JNC VI. Arch Intern Med. 1997;157:2413-2446 JNC 7. JAMA. 2003;289(19):2560-2572. 6/30/2014 13
  • 14. New Blood Pressure Norms for Children Normotensive Average SBP and DBP <90th % for age, sex and height Pre-hypertension Average SBP or DBP >90th but <95th percentile (OR >120/80) Hypertension Average SBP and/or DBP >95th percentile for age, sex and height on 3 separate occasions Stage 1: 95th-99th percentile + 5 mmHg Stage 2: >99th percentile + 5 mm Hg 6/30/2014 14
  • 15. How to use the percentile tables? Need: Age, gender, height percentage BP charts 6/30/2014 15
  • 16. 7 yo boy Ht 75%tile http://www.cc.nih.gov/ccc/pedweb/pedsstaff/bptable1.PDF 50% 99/58 90% 113/73 95% 119/80 99% 127/88 6/30/2014 16
  • 17. BP tables for Infants *Task Force on Blood Pressure Control in Children. Report of the Second Task Force on Blood Pressure Control in Children—1987.Pediatrics.1987;79:1–25(PR) 6/30/2014 17
  • 19. DINAMAP Oscillometric wrist BP monitor Ambulatory BP monitor Mercury sphygmanometer Aneroid BP monitor 6/30/2014 19
  • 20. Which blood pressure apparatus is the “Gold standard” for BP measurement in children above age 3? A. DINAMAP B. Oscillometric wrist BP monitor C. Ambulatory BP monitor D. Mercury sphygmanometer E. Aneroid BP monitor 6/30/2014 20
  • 22. Mercury Sphygmomanometry 1998: EPA and the American Hospital Association agreed to virtually eliminate mercury from hospitals by 2005 6/30/2014 22
  • 23. Aneroid Manometer Mercury pressure gauge replaced by mechanical spring Gauges are often small Accuracy varies among manufacturers Requires frequent calibration 6/30/2014 23
  • 25. Mercury and Aneroid Manometer 6/30/2014 25
  • 26. Testing the Aneroid Manometer  Does the needle rest at zero?  Inflate to 200 mm Hg. Wait for 1 minute, if lower than 170 suspect leak  Using the Y connector, connect to mercury device and check readings  If any reading is off by >4 mm, remove from service  Date the calibration 6/30/2014 26
  • 27. Oscillometric Devices Office Use Expensive (approximately $3000) Many have been validated (BHS, AAMI) Recommended for children of all ages Home Use Relatively inexpensive Few have been validated in children Not recommended for ages < 4 years 6/30/2014 27
  • 28. Oscillometric Devices Measure mean arterial pressure (MAP) and calculates SBP and DBP The algorithms used are proprietary and NOT standardized Results can vary widely and they do not always closely match BP values obtained by auscultation These machines must be calibrated regularly 6/30/2014 28
  • 29. Dinamap® Oscillometric Device Dinamap® is an acronym for: Device for Indirect Noninvasive Mean Arterial Pressure 6/30/2014 29
  • 30. Manual vs. Automatic Manual is the gold standard Oscillometric measurements preferred in infants and ICU settings ONLY All high readings should be confirmed with a manual 6/30/2014 30
  • 32. What is being measured? Auscultatory method: relies on relationship between audible Korotkoff sounds and pressure at systole and diastole Oscillometric method: relies on the amplitude of oscillations in the arterial wall to determine MAP (maximum amplitude); complex and proprietary algorithms used to estimate SBP and DBP Mean arterial pressure (MAP) is average pressure throughout the cardiac cycle. MAP=(SBP)+2(DBP)/3 6/30/2014 32
  • 33. Ambulatory BP Monitoring Oscillometric or acoustic methods 24 hour monitoring Individual measurements not more accurate Readings downloaded into PC Cost: $2500-4500 6/30/2014 33
  • 34. Ambulatory Blood Pressure Monitoring 6/30/2014 34
  • 36. Ambulatory Blood Pressure Monitoring 6/30/2014 36
  • 37. Blood pressure is measured in preferably on ? A. Right lower leg B. Left upper arm C. Right upper arm D. Left wrist E. Right wrist 6/30/2014 37
  • 38. Auscultatory Method Sitting quietly for 5 minutes Back supported and feet on the floor Right arm supported, cubital fossa at heart level Estimate systolic BP by palpation, re-inflate cuff to 20 mmHg higher 6/30/2014 38
  • 39. What is the optimal rate of deflation of blood pressure cuff? A. 1 mm Hg/sec B. 2-3 mm Hg/sec C. 5 mm Hg/sec D. 10 mm Hg/sec 6/30/2014 39
  • 40. Auscultatory Method Deflate cuff at 2-3 mmHg/sec Systolic BP= onset tapping sounds* Diastolic BP= disappearance of sounds (fifth Korotkoff sound) Record BP twice on each occasion as right arm, sitting, SBP/DBP(K5), average used to estimate BP level 6/30/2014 40
  • 41. Characteristics of Korotkoff sounds. 6/30/2014 41
  • 42. Auscultatory Method DBP is determined by disappearance of Krotkoff sounds (K5) Sometime Krotkoff sounds heard till 0 mm Hg Try less pressure on the head of stethoscope If K5 still persists K4 should be recorded as DBP 6/30/2014 42 Fourth report on BP. Pediatrics August 2004
  • 43. Summary Accurate blood pressure measurement is the corner stone of diagnosis of hypertension Oscillatory method can be used for screening but elevated blood pressure should be confirmed with auscultatoy method Appropriately sized cuff is mandatory and measure mid arm circumference to choose the cuff size Calibrate BP measurement apparatus semiannually 6/30/2014 43
  • 45. Quiz 1. When Measuring the Blood Pressure all statement below are true EXCEPT A. Correct measurement of the blood pressure (BP) is essential in the diagnosis and management of hypertension. B. It is essential that BP machines are properly calibrated. C. Appropriate cuff sizes are needed for children D. When BP is measured in an office-based setting, personnel training does not interfere the measurement. E. The position of patient impact the BP readings. 6/30/2014 45
  • 46. Quiz 1. When Measuring the Blood Pressure all statement below are true EXCEPT A. Correct measurement of the blood pressure (BP) is essential in the diagnosis and management of hypertension. B. It is essential that BP machines are properly calibrated. C. Appropriate cuff sizes are needed for children D. When BP is measured in an office-based setting, personnel training does not interfere the measurement. E. The position of patient impact the BP readings. 6/30/2014 46
  • 47. Quiz 2. All statements below are true, EXCEPT A. Cuff too small lead to falsely high BP reading B. Cuff too big usually not lead to falsely low BP reading C. Lower extremities BP reading is 10 to 20 mmHg lower than the arms D. Right arm is the prefer arm if at all possible E. Right arm for comparison with standards 6/30/2014 47
  • 48. Quiz 2. All statements below are true, EXCEPT A. Cuff too small lead to falsely high BP reading B. Cuff too big usually not lead to falsely low BP reading C. Lower extremities BP reading is 10 to 20 mmHg lower than the arms D. Right arm is the prefer arm if at all possible E. Right arm for comparison with standards 6/30/2014 48
  • 49. Quiz 3. Which of the following Staging of Hypertension is not TRUE ? A. Normal Blood pressure is systolic <120 and diastolic < 80 B. Pre hypertension include systolic 120-140 and diastolic 80-90 C. Stage 1 hypertension is systolic > 150 D. Stage 1 hypertension is diastolic > 90 E. Stage 2 hypertension is Systolic > 160 6/30/2014 49
  • 50. Quiz 3. Which of the following Staging of Hypertension is not TRUE ? A. Normal Blood pressure is systolic <120 and diastolic < 80 B. Pre hypertension include systolic 120-140 and diastolic 80-90 C. Stage 1 hypertension is systolic > 150 D. Stage 1 hypertension is diastolic > 90 E. Stage 2 hypertension is Systolic > 160 6/30/2014 50
  • 51. QUIZ 4. What is being measured? TRUE / FALSE A. Auscultatory method relies on relationship between audible Korotkoff sounds and pressure at systole and diastole. B. Oscillometric method relies on the amplitude of oscillations in the arterial wall to determine MAP (maximum amplitude). C. Mean arterial pressure (MAP) is average pressure throughout the cardiac cycle. 6/30/2014 51
  • 52. QUIZ 4. What is being measured? TRUE / FALSE A. Auscultatory method relies on relationship between audible Korotkoff sounds and pressure at systole and diastole. TRUE B. Oscillometric method relies on the amplitude of oscillations in the arterial wall to determine MAP (maximum amplitude). TRUE C. Mean arterial pressure (MAP) is average pressure throughout the cardiac cycle. TRUE 6/30/2014 52