4. PRIMARY
SOURCES
SECONDARY
SOURCES
Feces and urine
of cases and
carriers
Contaminated
• Food
• Water
• Milk
• Flies
• finger
MODE OF TRANSMISSION
• Feaco-oral route
• Urine oral route
RESEVOIR OF INFECTION
• Man is the only reservoir and may exist as a case or a carrier
INCUBATION PERIOD
10 -14 days
9. CONTROL
CONTROL OF RESERVIOR
Case control:
Chloramphenicol, cortimoxazole, amoxicillin
Carrier:
ampicillin, probenecid+cholecystectomySANITATION CONTROL
Clean water preservation
Food hygiene
Health education
IMMUNIZATION
Given at >1 year
Anti-typhoid vaccine:
Monovalent( immunity against only 1 antigen source)
Divalent (immunity against both typhi, paratyphi)
TAB VACCINE (Typhi, paratyphiA&B)
DOSE: 2 doses 0.5ml every month subcutaneously
BOOSTER DOSE: after every 3 years
10. TREATMENT OF TYPHOID FEVER:
• Chloramphenicol for 5-7 days
• Low caloric diet with soups, vegetables, milk, eggs and
potatoes.
• CIPROFLOXACIN is now drug of choice.
11. CARRIER PRESENCE OF DISEASE TIME PERIOD
Convalescent carrier After onset of
symptoms→50% pt.
secrete S.typhi in feces.
3 weeks after onset
Healthy Carrier Clinically unrecognized
disease
--
Chronic Permanent Carrier No typhoid fever at the
time but still discharge
S.typhi
After 12 months of post-
infection