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LAB INVESTIGATIONS AND
DIAGNOSIS
Diabetes Mellitus
 WHO criteria for diagnosis of metabolic
syndrome is-
Any one of the following Any two of the following
DM Blood pressure: ≥ 140/90
Impaired fasting glucose TG >150 and HDL <35 M & < 40F
Impaired glucose tolerance WHR >0.9 M & >0.85 F or BMI >30
Insulin resistance urinary albumin excretion ≥ 20 µg/min
or albumin : creatinine ratio ≥ 30 mg/g
Diagnostic criteria for DM
Any one of the following is diagnostic
A. Glucose
1. Fasting plasma glucose ≥126 mg% or
2. Symptoms of hyperglycemia and
casual plasma glucose ≥200mg% or
3. During an OGTT 2 hour plasma glucose ≥ 200mg%
B. HbA1c ≥ 6.5 mg%
others
 Microalbuminuria
 Evaluating complications- lipid profile, ketone
bodies, electrolytes, lactate etc.
 HOMA-IR = insulin (mU/L) * glucose (mg%) / 405
 C-peptide assessment.
Thank you…

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LAB DIAGNOSIS N INVESTIGATION OF DIABETES MELLITUS.

  • 2.  WHO criteria for diagnosis of metabolic syndrome is- Any one of the following Any two of the following DM Blood pressure: ≥ 140/90 Impaired fasting glucose TG >150 and HDL <35 M & < 40F Impaired glucose tolerance WHR >0.9 M & >0.85 F or BMI >30 Insulin resistance urinary albumin excretion ≥ 20 µg/min or albumin : creatinine ratio ≥ 30 mg/g
  • 3. Diagnostic criteria for DM Any one of the following is diagnostic A. Glucose 1. Fasting plasma glucose ≥126 mg% or 2. Symptoms of hyperglycemia and casual plasma glucose ≥200mg% or 3. During an OGTT 2 hour plasma glucose ≥ 200mg% B. HbA1c ≥ 6.5 mg%
  • 4.
  • 5.
  • 6.
  • 7.
  • 8. others  Microalbuminuria  Evaluating complications- lipid profile, ketone bodies, electrolytes, lactate etc.  HOMA-IR = insulin (mU/L) * glucose (mg%) / 405  C-peptide assessment.