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Lars Juhl Jensen
Open data and open access
A biomedical data- and text-mining
perspective
>10 km
too much to read
even more data
unknown what is known
molecular biology
support for open science
public databases
data deposition required
open access publishing
integrative resources
data/text mining
knowledge overview
string-db.org
open licenses
medicine
Jensen et al., Nature Reviews Genetics, 2012
opposition to open science
clinical trial data hidden
“research parasites”
valid privacy concerns
direct benefits for patients
roadmap of diseases
Jensen et al., Nature Communications, 2014
6 million Danish patients
pharmacovigilance
Eriksson et al., Drug Safety, 2014
Drug introduction Drug discontinuation
Adverse eventNegative modifier Indication Pre-existing
condition
Adverse drug reaction Possible
adverse drug reaction
Adverse event
ADR of
additional drug
Identification start
discover new ADRs
only 3,394 patients
magine Europe-wide studie

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