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Peripheral giant cell granuloma (giant cell epulis
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Central Giant Cell Granuloma : WHO has defined it as an intraosseous lesion consisting of cellular and fibrous tissue that contains multiple foci of hemorrhage, aggregation of multinucleated giant cells and occasionally trabaculae of woven bone Etiology JAFFE (1953): considered this lesion to be a local reparative reaction of bone, possibly to intramedullary hemorrhage or trauma, hence the term reparative giant cell granuloma was accepted. Charles A Waldron & W G Shafer (1966) suggested trauma be an important etiological factor in the initiation of the CGCG of the jaws Thoma K H (1986) suggested that the lesion may be due to capillary injury caused by defective wall due to some type of trauma J V Soames and J C Southam (1997) suggested that it could be a reaction to some form of hemodynamic disturbance in bone marrow, perhaps associated with trauma and hemorrhage REGEZI AND SCIUBBA(1999) : Suggested that Response to previous traumatic or inflammatory episodes. This lesion is charecterised by proliferation of fibroblasts and multinucleated giant cells, in a densely packed stromaThe CGCG is a benign process that occurs almost exclusively within the jaw bones CLINICAL PRESENTATION Found predominantly in children and young adult It has a female predilection (2:1) Most commonly affected site is the anterior portion of the jaws, with an increased frequency of occurrence in the mandible Majority of the CGCG of jaws are painless, expansion of bone is detected on routine examination Few cases may be associated with pain, paresthesia or perforation of a cortical bone plate, occasionally resulting in the ulceration of the mucosal surface by the underlying lesion Radiographic featuresCentral giant cell lesions present as radiolucent defects. Which may be unilocular or multilocular. The defect is usually well delineated The lesion may vary from a 5×5mm incidental radiographic findings to a destructive lesion greater than 10cm in size. radiographic findings A small unilocular lesion may be confused with periapical granuloma or cysts. multilocular giant cell lesions cannot be radiographically distinguished from ameloblastomas or other multilocular lesions. Based on clinical and radiological features CGCG may be divided into two categories - Non-aggressive lesion - Aggressive lesion The non aggressive lesion makes up most cases and exhibit few or no symptoms, they demonstrate slow growth and do not show cortical perforation or root resorption of teeth involved in the lesion. The aggressive lesions are characterized by pain, rapid growth, cortical perforation and root resorption and show marked tendency to recur when compared with non aggressive typeSoft spongy, brownish to reddish friable tissue of various size. A specimen is usually coated with fresh or coagulated blood. Giant cell lesions of the jaws show a variety of features. Common to all is the presence of few to many multinucleated
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SOC 101 Demonstration of Learning Presentation
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Unit-V; Pricing (Pharma Marketing Management).pptx
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TỔNG ÔN TẬP THI VÀO LỚP 10 MÔN TIẾNG ANH NĂM HỌC 2023 - 2024 CÓ ĐÁP ÁN (NGỮ Â...
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Unit-IV; Professional Sales Representative (PSR).pptx
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Making communications land - Are they received and understood as intended? we...
This PowerPoint helps students to consider the concept of infinity.
This PowerPoint helps students to consider the concept of infinity.
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Magic bus Group work1and 2 (Team 3).pptx
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SKILL OF INTRODUCING THE LESSON MICRO SKILLS.pptx
microwave assisted reaction. General introduction
microwave assisted reaction. General introduction
Peripheral giant cell granuloma (giant cell epulis
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GIANT CELLS LESIONS
OF THE JAW DEPARTMENT OF ORAL MEDICINE
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Giant cells
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Peripheral Giant Cell
Granuloma (Giant Cell Epulis ) Dept: of Oral medicine UDM ( Mdy:)
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CGCG
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Thank You
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