1. Heart -Pathology
Neoplasms
Rare in general
MC are benign
Myxoma
MC primary benign cardiac neoplasm in adults
Single
If multiple with spotty pigmentation, endocrine problems= CARNEY
syndrome)
Clinical obstruct Mitral valve ( like Ball-valve), systemic effects due to
IL-6
Diagnosis Echo but confirmation is by pathology
Rx= excision is curative
Rhabdomyoma
MC primary benign neoplasm of infants & Children
↑frequency with Tuberous Sclerosis
Pathogenesis= defective apoptosis in cardiac embryogenesis
Pathology = spider cells
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Dr. Krishna Tadepalli, MD, www.mletips.com