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JPI Conference Dublin Plenary Session Philippe Amouyel
1. Joint Programming as a response to
societal challenges
Joint Programming Initiative on Neurodegenerative
Diseases:
The Next Challenges
Prof. Philippe Amouyel
Chair, JPND Management Board
2. Alzheimer’s and Neurodegenerative
Diseases in Europe
Alzheimer’s Number of cases Societal costs (€)
2010 6,000,000 72,000,000,000
2040 12,000,000 144,000,000,000
A major societal
challenge for the
coming years
3. The JPND goals
To tackle the challenge of Alzheimer’s and other neurodegenerative diseases*,
the goals of the JPND Research Strategy are:
• To develop new treatments and preventive strategies
• To improve health and social care approaches
• To raise awareness and de-stigmatise neurodegenerative disorders
• To alleviate the economic and social burden of these diseases
* Alzheimer’s disease and other dementias (AD), Parkinson’s disease (PD) and PD-related
disorders, Prion disease, motor neurone diseases (MND), Huntington’s disease (HD),
spinocerebellar ataxia (SCA), spinal muscular atrophy (SMA)
5. JPND - Clearing Steps
• The Foundations
• Agree on a Common Vision
• Build Trust
• Define Terms of Reference
• Structure the Governance
• Working Together
• The Strategic Research Agenda
• The Implementation
• Towards Sustainability
7. JPND Research Strategy (SRA)
• What is it?
• A holistic ‘roadmap’ for future EU-wide activity and investment
• Not a review of the field, not a list of calls for proposals
• Launched Feb 7th, 2012
• 5 research priorities, 9 enabling activities
• Delivery has taken into account
• SAB recommendations
• Outputs from 4 scientific/strategic workshops
• National and European portfolios
• Mapping exercise of National and European programmes
• Broad consultation with stakeholder groups
• Both Online and Offline
8. A European Challenge
“The answers to these challenges will be found in science and research.
This Research Strategy comes not a moment too soon. It provides a
much-needed framework for European-level coordination and investment
in neurodegenerative disease research.”
Mrs Máire Geoghegan-Quinn European
Commissioner for Research, Innovation and Science
Launch of the Research Strategy of JPND
Brussels, 7 February 2012
9. Next Steps
• The JPI must have clear and quantifiable scientific objectives to propose
• The SRA alone is not sufficient
• It is only a holistic roadmap
• An implementation plan is compulsory
• Objectives must be in-line with the scientific strategy of each country
• Some countries have their own National Plan
• Others need to build one
10. The Implementation Plan
• Create list of priorities from JPND Research Strategy proposals
• Organise thematic working groups
• Create list of opportunities suited for implementation
• Organise specific task forces
• Stimulate and align National Plans
• Set action groups for specific priorities and encouraging collaborations
• Support implementation
11. Some achievements
• Creation of stable management structure with efficient procedures
• Mapping exercise and associated public database
• JPND Joint Transnational Calls:
• One in 2011 for €15M ; Two in 2012-2013 for €25M
• Centres of Excellence in Neurodegeneration program:
• 2011 for €6M ; in 2012-13 for €8M
• Opening up to Third Countries:
• Canada already, on-going discussions with US
12. The next Challenges
• To implement over time
• To partner with EU
• To partner with industry
• To ensure JPND sustainability
13. To implement over time
• Developing attractive programs
• Easier when a National Plan already exists
• Always « a la carte »
• Need for synchronisation of funding decisions in each country (yearly basis)
• Strengthing decisions by signing Memorandum of Understanding
• Importance of phasing and overlap
• Diversity of the tools
14. To partner with EU
• Establish a programme of co-investment
• Work towards a sustained increased of the investment amongst JPND partners
• Leverage the value of investments and resources at both national and European
Commission level, to the benefit of Europe
Examples:
•Synergy between JPND actions and H2020 programme
•Linking national plans through actions engaging national infrastructures
•Development and long term sustainability of European cohorts
•Unlocking national capability on fellowship program
15. To partner with Industry
• Participation in the Research Strategy delivery
• Enlarge the contacts (pharma, device, IT, diagnosis, imaging, welfare
technologies, AAL, …)
• Ongoing discussions with IMI
• Not a single mechanism to interact for companies
• access to infrastructures and clinical networks
• associate in JPND calls
• set up an educational program
16. To ensure JPND sustainability
• JPND is supported by the CA Jumpahead
• Improve / achieve efficiency
• Provide points of influence of key stakeholders
• Inclusive of member states interest
• Permanent full time senior management resources
• Cash / in-kind contributions from member states
• Legal structure
17. Joining forces
to fight neurodegenerative diseases
‘We hope that JPND will be a successful pilot for research into
other challenges, as well as lead to a reduction in the burden of
neurodegenerative diseases.’
www.thelancet.com/neurology Vol 12 February 2013, Editorial p119
18. Keep up to date
• Visit the JPND website:
• http://www.neurodegenerationresearch.eu
• http://www.jpnd.eu
• Search our Mapping Database
• Sign up to the JPND News Feeds
• E-mail us: secretariat@jpnd.eu
• Follow us on Twitter: @JPNDEurope