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Building Pyramids:
Designing HIV Prevention and Treatment
Systems for Drug Users in Eastern Europe

Dr. Jean-Paul C. Grund
Building Pyramids
Introduction
• While not absent during the days of communist rule, the transition
towards democracy has undoubtedly been followed by an increase in
the availability and use of illicit drugs in all former socialist
countries.
• As a result, injecting drug use, addiction and, as a consequence, HIV
are developing into a serious public health problem.
• Addiction is associated with compromised economic, social and
psychological situations.
• It is increasingly viewed as a complex, multi-causal, chronic
relapsing condition or disease, for which ”to date there is no effective
curative treatment.”
10/18/01, Building Pyramids

J-P Grund
Drug Use after Socialism:
Prevalence Russia & Ukraine
Table 1. Registered & Estimated Number of Drug Users in Russia & Ukraine

Russia
Registered Number of Drug Users
Ministry of Internal Affairs:
Ministry of Health:

1 99 0

19 94
19 96
20 01
158.000 249.000
25.000
85.000 450.000 (Users)
270.000 (Addicts)

Estimates:

1996: 600,000
1998: 1-2.5 million
2001: LTP: 3 million

Ukraine
Registered Number of Drug Users:

“Early 1990s”: 20.000; 1997: 80.000

Estimate (MIA):

1997: 600.000 – 700.000 (75 - 80% IDUs)

Sources: Brunet 1996; USAID/CDC 1998; Khodakevich & Dehne 1998; Dehne et al. 1999; MOH, 2001
Drug Use after Socialism:
Prevalence in Cities Across the CEE Region
Table 2. Total Number of IDUs and Percentage of Population by City

Sources:
• MSF/H RSAs
• Grund et al. 2001

City
Total IDUs % of Population
35000
2.6
Nizhniy Novgorod
9000
3.6
Novorossiisk
380-440
0.2
Pskov
10000
1
Rostov Na Donu
70-80000
1.7-1.9
St. Petersburg
18000
1.7
Volgograd
25000
2
Odessa
up to 10000
3
Poltava
7000-8000
0.4-0.5
Estonia
2000-3000
0.3-0.5
Vilnius
1416
0.2
Kishineu
15-20000
1-1.5
Sofia
2500
1
Szeged
Drug Use after Socialism:
Qualitative Prevalence Assessments

“People drink or inject in this place.”
(Outreach suggest that
Both national and city-level dataWorker, Volgograd) in
several NIS countries more than 1% of the
population is involved in (injecting) drug use.
“It is difficult to find a building in this
town that is not affected by drug use.”
(Epidemiologist, Rostov Na Donu)

10/18/01, Building Pyramids

J-P Grund
Drug Use under Socialism: Do It Yourself!
Collective Drug
Preparation & Injecting,

Friendship Networks,

& HIV Transmission
A Culture of Collective Drug Use

10/18/01, Building Pyramids

J-P Grund
A Culture of Collective Drug Use
“It is very seldom when you use alone. At minimum you use with two or
three people. … “Somebody has money for drugs, a second knows where
to get good drugs, a third has some anhydride or a place to cook and yet
another has syringes. … It is also much cheaper to use in groups.”
0
Ap 0
r01
Ju
l-0
1

99

98

97

96

95

94

93

92

71

5

17
70
16
10
59
2

26

10

87

7

9

3

1

8

71

60

52

44

33

70

23

26

05

40000

20

19

19

19

19

19

19

19

19

91

90

89

88

87

20000

19

19

19

19

19

4

80

160000

140000

120000

1 1
15
03
0,
,0
00
24
0

100000

35

Cumulative number of reported HIV cases
Russian Federation, 1987 - July 1, 2001

80000

60000

0
Building Pyramids:
A Model for Policy & Service Development
• Metaphorical model of the development of drug treatment
and health & social care services for drug users.
• The model is essentially a thinking model to support realistic
policy development.
• It includes graphical representations
of key variables and processes,
relevant to decision making.
• It can inform a range of
policy choices, considering and
matching these key variables.
10/18/01, Building Pyramids

J-P Grund
Pyramid Model:
Establishing a Typology of Care Services for IDUs

Threshold to Care
High Threshold Services
Medium Threshold Services
Low Threshold Services

‘No’ Threshold Services
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Professional Care Services for IDUs

High Threshold Services
• In-Patient Detoxification
(Reduction, Cold Turkey)
• Mid-Term In-Patient
Treatment
• (Long-Term) Residential
Therapeutic Communities
• Psychiatric Interventions
• After Care, Rehab, Relapse
Prevention, Acupuncture
• (Re-Entry) Housing
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Professional Care Services for IDUs

Medium Threshold Services
• Out-Patient Detoxification
(Reduction, Acupuncture)
• Specialized Medical
Treatment (HIV, HBV,
HCV, Dental Problems)
• Social Work, Counseling,
Case Management
• Job Training, Work
• (Supported) Housing
• Money Management
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Professional Care Services for IDUs
Low Threshold Services
• Out-Patient Opiate Agonist
Treatment: Methadone,
Buprenorphine, Codeine
• Emergency Medical and
General Practice Care
• (Emergency) Psychiatry
• Syringe Access: Exchange,
Distribution, Pharmacy e.a.
Sales (kiosks-coupons?)
• Outreach Work
• Overdose Prevention
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Professional Care Services for IDUs

Low Threshold Services
• Drop-In Centers,
• Safer Consumption Facilities
• Food, Clothing and Shelter
Projects
• Drug Use Management
programs
• Acupuncture, Stress
Reduction
• Safer Drug Use Information
• Chill-Outs @ R@ves
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
A Dynamic Model
Key Characteristics
• Easy access @ multiple
entry points.
• Includes all service levels
• (coordinated) transfer
between services.
• Easy use of ancillary services
• Increases demand for high
threshold treatment: develops
naturally with growing contact rates.
• Can reach 70-80% of IDUs.
• Collaborative Model.
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Considerations for Setting Priorities
Public Health Considerations
• Fighting the HIV/AIDS Pandemic
and Other Infectious Diseases
• Reducing Drug-related Morbidity
and Mortality
• Coverage of Populations at Risk
• Treatment Retention
• Treatment of Problem Drug Use

Economic considerations
• Available $$ Resources (Funding)
• Costs of Services
10/18/01, Building Pyramids

J-P Grund
Coverage: What proportion of the
IDU Population Needs to be Reached?

Slide: Courtesy of S. Strathdee
10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Care Services for IDUs: Level & Coverage

Level of Care

Potential Coverage of Population (%)

High Threshold Services

1-20 (?)

Medium Threshold Services

15-40 (?)

Low Threshold Services

70-80

‘No’ Threshold Services

Nx

10/18/01, Building Pyramids

J-P Grund
Pyramid Model
Treatment Costs by Type of Modality

Type of Treatment

Relative Costs per Treated Drug User
$$$

High Threshold Services

$$-$$$

Medium Threshold Services

$

Low Threshold Services

Q: Where to Invest Scarce Resources?
A: Where we get the Biggest
10/18/01, Building Pyramids

Bang for the Buck!

J-P Grund
Mean Costs Per Year For 1 Heroin Addict (USA)
$
50000
40000

Security

30000
Theft, etc.

20000
10000

Heroin

Jail
or
Prison
and
Court
Costs

0
On Street

Incarcerated

Residential
Drug-Free
Treatment

MMT

Residential
Treatment

Methadone
Maintenance
Treatment
SOURCE: Slide: M. Reisinger, Adapted from NYS DSAS, 1991, by Dole & Des Jarlais.
10/18/01, Building Pyramids

J-P Grund
Conclusion
Building Pyramids: A Useful Metaphor for
Development of Drug Policy and Services?
• Pyramids were not built in one
day. Nor are treatment services
for Injecting Drug Users.
• Pyramids were built stone
for stone, layer for layer,
fitting seamlessly on the
preceding layer.
• Pyramids were built to last:
Sustainable Development
• Ancient Architectural Rule:
Start with the Fundament(al)s.
10/18/01, Building Pyramids

J-P Grund

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Pyramid unaids 10 19-01 (v2)

  • 1. Building Pyramids: Designing HIV Prevention and Treatment Systems for Drug Users in Eastern Europe Dr. Jean-Paul C. Grund
  • 2. Building Pyramids Introduction • While not absent during the days of communist rule, the transition towards democracy has undoubtedly been followed by an increase in the availability and use of illicit drugs in all former socialist countries. • As a result, injecting drug use, addiction and, as a consequence, HIV are developing into a serious public health problem. • Addiction is associated with compromised economic, social and psychological situations. • It is increasingly viewed as a complex, multi-causal, chronic relapsing condition or disease, for which ”to date there is no effective curative treatment.” 10/18/01, Building Pyramids J-P Grund
  • 3. Drug Use after Socialism: Prevalence Russia & Ukraine Table 1. Registered & Estimated Number of Drug Users in Russia & Ukraine Russia Registered Number of Drug Users Ministry of Internal Affairs: Ministry of Health: 1 99 0 19 94 19 96 20 01 158.000 249.000 25.000 85.000 450.000 (Users) 270.000 (Addicts) Estimates: 1996: 600,000 1998: 1-2.5 million 2001: LTP: 3 million Ukraine Registered Number of Drug Users: “Early 1990s”: 20.000; 1997: 80.000 Estimate (MIA): 1997: 600.000 – 700.000 (75 - 80% IDUs) Sources: Brunet 1996; USAID/CDC 1998; Khodakevich & Dehne 1998; Dehne et al. 1999; MOH, 2001
  • 4. Drug Use after Socialism: Prevalence in Cities Across the CEE Region Table 2. Total Number of IDUs and Percentage of Population by City Sources: • MSF/H RSAs • Grund et al. 2001 City Total IDUs % of Population 35000 2.6 Nizhniy Novgorod 9000 3.6 Novorossiisk 380-440 0.2 Pskov 10000 1 Rostov Na Donu 70-80000 1.7-1.9 St. Petersburg 18000 1.7 Volgograd 25000 2 Odessa up to 10000 3 Poltava 7000-8000 0.4-0.5 Estonia 2000-3000 0.3-0.5 Vilnius 1416 0.2 Kishineu 15-20000 1-1.5 Sofia 2500 1 Szeged
  • 5. Drug Use after Socialism: Qualitative Prevalence Assessments “People drink or inject in this place.” (Outreach suggest that Both national and city-level dataWorker, Volgograd) in several NIS countries more than 1% of the population is involved in (injecting) drug use. “It is difficult to find a building in this town that is not affected by drug use.” (Epidemiologist, Rostov Na Donu) 10/18/01, Building Pyramids J-P Grund
  • 6. Drug Use under Socialism: Do It Yourself!
  • 7. Collective Drug Preparation & Injecting, Friendship Networks, & HIV Transmission
  • 8. A Culture of Collective Drug Use 10/18/01, Building Pyramids J-P Grund
  • 9. A Culture of Collective Drug Use “It is very seldom when you use alone. At minimum you use with two or three people. … “Somebody has money for drugs, a second knows where to get good drugs, a third has some anhydride or a place to cook and yet another has syringes. … It is also much cheaper to use in groups.”
  • 11. Building Pyramids: A Model for Policy & Service Development • Metaphorical model of the development of drug treatment and health & social care services for drug users. • The model is essentially a thinking model to support realistic policy development. • It includes graphical representations of key variables and processes, relevant to decision making. • It can inform a range of policy choices, considering and matching these key variables. 10/18/01, Building Pyramids J-P Grund
  • 12. Pyramid Model: Establishing a Typology of Care Services for IDUs Threshold to Care High Threshold Services Medium Threshold Services Low Threshold Services ‘No’ Threshold Services 10/18/01, Building Pyramids J-P Grund
  • 13. Pyramid Model Professional Care Services for IDUs High Threshold Services • In-Patient Detoxification (Reduction, Cold Turkey) • Mid-Term In-Patient Treatment • (Long-Term) Residential Therapeutic Communities • Psychiatric Interventions • After Care, Rehab, Relapse Prevention, Acupuncture • (Re-Entry) Housing 10/18/01, Building Pyramids J-P Grund
  • 14. Pyramid Model Professional Care Services for IDUs Medium Threshold Services • Out-Patient Detoxification (Reduction, Acupuncture) • Specialized Medical Treatment (HIV, HBV, HCV, Dental Problems) • Social Work, Counseling, Case Management • Job Training, Work • (Supported) Housing • Money Management 10/18/01, Building Pyramids J-P Grund
  • 15. Pyramid Model Professional Care Services for IDUs Low Threshold Services • Out-Patient Opiate Agonist Treatment: Methadone, Buprenorphine, Codeine • Emergency Medical and General Practice Care • (Emergency) Psychiatry • Syringe Access: Exchange, Distribution, Pharmacy e.a. Sales (kiosks-coupons?) • Outreach Work • Overdose Prevention 10/18/01, Building Pyramids J-P Grund
  • 16. Pyramid Model Professional Care Services for IDUs Low Threshold Services • Drop-In Centers, • Safer Consumption Facilities • Food, Clothing and Shelter Projects • Drug Use Management programs • Acupuncture, Stress Reduction • Safer Drug Use Information • Chill-Outs @ R@ves 10/18/01, Building Pyramids J-P Grund
  • 17. Pyramid Model A Dynamic Model Key Characteristics • Easy access @ multiple entry points. • Includes all service levels • (coordinated) transfer between services. • Easy use of ancillary services • Increases demand for high threshold treatment: develops naturally with growing contact rates. • Can reach 70-80% of IDUs. • Collaborative Model. 10/18/01, Building Pyramids J-P Grund
  • 18. Pyramid Model Considerations for Setting Priorities Public Health Considerations • Fighting the HIV/AIDS Pandemic and Other Infectious Diseases • Reducing Drug-related Morbidity and Mortality • Coverage of Populations at Risk • Treatment Retention • Treatment of Problem Drug Use Economic considerations • Available $$ Resources (Funding) • Costs of Services 10/18/01, Building Pyramids J-P Grund
  • 19. Coverage: What proportion of the IDU Population Needs to be Reached? Slide: Courtesy of S. Strathdee 10/18/01, Building Pyramids J-P Grund
  • 20. Pyramid Model Care Services for IDUs: Level & Coverage Level of Care Potential Coverage of Population (%) High Threshold Services 1-20 (?) Medium Threshold Services 15-40 (?) Low Threshold Services 70-80 ‘No’ Threshold Services Nx 10/18/01, Building Pyramids J-P Grund
  • 21. Pyramid Model Treatment Costs by Type of Modality Type of Treatment Relative Costs per Treated Drug User $$$ High Threshold Services $$-$$$ Medium Threshold Services $ Low Threshold Services Q: Where to Invest Scarce Resources? A: Where we get the Biggest 10/18/01, Building Pyramids Bang for the Buck! J-P Grund
  • 22. Mean Costs Per Year For 1 Heroin Addict (USA) $ 50000 40000 Security 30000 Theft, etc. 20000 10000 Heroin Jail or Prison and Court Costs 0 On Street Incarcerated Residential Drug-Free Treatment MMT Residential Treatment Methadone Maintenance Treatment SOURCE: Slide: M. Reisinger, Adapted from NYS DSAS, 1991, by Dole & Des Jarlais. 10/18/01, Building Pyramids J-P Grund
  • 23. Conclusion Building Pyramids: A Useful Metaphor for Development of Drug Policy and Services? • Pyramids were not built in one day. Nor are treatment services for Injecting Drug Users. • Pyramids were built stone for stone, layer for layer, fitting seamlessly on the preceding layer. • Pyramids were built to last: Sustainable Development • Ancient Architectural Rule: Start with the Fundament(al)s. 10/18/01, Building Pyramids J-P Grund