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International Journal of Trend in
International Open Access Journal
ISSN No: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Real Time Signal Quali
Framework for FPGA
Development o
Dhanashri
Department of Technology,
ABSTRACT
Day by day the scope & use of the electronics
concepts in bio-medical field is increasing gradually.
A novel approach to the design of real time ECG
signal acquisition system for patient mo
medical application, FPGA (Field Programmable Gate
Array) is the core heart of proposed system which is
configured and programmed to acquire using ECG
(Electrocardiogram) sensor. In this paper a new
concept of ECG telemetry system is discussed
with signal quality aware IoT framework for energy
efficient ECG monitoring system. Tele monitoring is
a medical practice that involves monitoring patients
who are not at the same location as the healthcare
provider. The purpose of the present study
identify heart condition and give the information to
the doctor. The objective of the study is to improve
the doctor-patient ratio and evaluation of cardiac
diseases in the rural population. The proposed system
for the electrocardiogram (ECG) mon
controlled by FPGA and implemented in the form of
android application.
Keyword- FPGA (Field programmable gate array),
Electrocardiogram (ECG) signals, IoT (Internet of
Things)
I. INTRODUCTION
The word electrocardiography is evolved from Greek
word Kardia which means Heart. ECG that is
electrocardiography is a process of interpretation of
heart activity over the period of time and is detected
by electrodes attached to the surface of body. An ECG
is used to measure the heart’s electrical conduction
system. It picks up electrical impulses generated by
the polarization and depolarization of cardiac tissue
and translates into a waveform. The waveform is then
used to measure the rate and regularity of
International Journal of Trend in Scientific Research and Development (IJTSRD)
International Open Access Journal | www.ijtsrd.com
ISSN No: 2456 - 6470 | Volume - 3 | Issue – 1 | Nov
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
Signal Quality Aware Internet of Things (IOT)
FPGA Based ECG Telemetry System and
Development of Android Application
Dhanashri P. Yamagekar, Dr. P. C. Bhaskar
f Technology, Shivaji University Kolhapur, India
Day by day the scope & use of the electronics
medical field is increasing gradually.
A novel approach to the design of real time ECG
signal acquisition system for patient monitoring in
FPGA (Field Programmable Gate
Array) is the core heart of proposed system which is
configured and programmed to acquire using ECG
In this paper a new
concept of ECG telemetry system is discussed along
with signal quality aware IoT framework for energy
efficient ECG monitoring system. Tele monitoring is
a medical practice that involves monitoring patients
who are not at the same location as the healthcare
provider. The purpose of the present study is use to
identify heart condition and give the information to
the doctor. The objective of the study is to improve
patient ratio and evaluation of cardiac
diseases in the rural population. The proposed system
for the electrocardiogram (ECG) monitoring
controlled by FPGA and implemented in the form of
FPGA (Field programmable gate array),
Electrocardiogram (ECG) signals, IoT (Internet of
The word electrocardiography is evolved from Greek
word Kardia which means Heart. ECG that is
electrocardiography is a process of interpretation of
heart activity over the period of time and is detected
by electrodes attached to the surface of body. An ECG
is used to measure the heart’s electrical conduction
system. It picks up electrical impulses generated by
the polarization and depolarization of cardiac tissue
and translates into a waveform. The waveform is then
used to measure the rate and regularity of heartbeats,
as well as the size and position of the chambers, the
presence of any damage to the heart, and the effects of
the drugs or devices used to regulate the heart, such as
a pacemaker.
A typical ECG tracing of normal heartbeat consists of
a P wave, a QRS complex and a T wave. Data
acquisition products server as a focal point in a
system, tying together a wide variety of products such
as sensor that indicate temperature, flow, levels, pulse
rate, electrocardiograph etc.
The core heart of the proposed system is field
programmable gate array (FPGA) which is configured
and programmed to acquire a real time data. Real time
data from the process is acquired using ECG sensor.
Signal conditioners are designed for each sensor.
Signal conditioners are interfaced with FPGA through
ADC and MAX 232 for PC interfacing. Output of the
system is displayed waveform on PC.
An electrocardiogram is a test that checks for problem
with the electrical activity of our heart. An ECG
translates the heart’s electrical act
tracing on paper. The spikes and dips in the line
tracing are called waves. The ECG signal consist of P,
Q, R, S, T waves. The function of each wave is
 P Wave- represents the atrial contraction
 QRS complex represents the ventricular
contraction.
 R peaks- represents a heartbeat.
 T wave- represent the last common wave in an
ECG. The electrical signal is produced when the
ventricles are repolarizing.
Research and Development (IJTSRD)
www.ijtsrd.com
1 | Nov – Dec 2018
Dec 2018 Page: 216
ty Aware Internet of Things (IOT)
lemetry System and
as well as the size and position of the chambers, the
presence of any damage to the heart, and the effects of
the drugs or devices used to regulate the heart, such as
A typical ECG tracing of normal heartbeat consists of
wave, a QRS complex and a T wave. Data
acquisition products server as a focal point in a
system, tying together a wide variety of products such
as sensor that indicate temperature, flow, levels, pulse
oposed system is field
programmable gate array (FPGA) which is configured
and programmed to acquire a real time data. Real time
data from the process is acquired using ECG sensor.
Signal conditioners are designed for each sensor.
terfaced with FPGA through
ADC and MAX 232 for PC interfacing. Output of the
system is displayed waveform on PC.
An electrocardiogram is a test that checks for problem
with the electrical activity of our heart. An ECG
translates the heart’s electrical activity into line
tracing on paper. The spikes and dips in the line
tracing are called waves. The ECG signal consist of P,
Q, R, S, T waves. The function of each wave is-
represents the atrial contraction
QRS complex represents the ventricular
represents a heartbeat.
represent the last common wave in an
ECG. The electrical signal is produced when the
ventricles are repolarizing.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Fig. 1- ECG signal Characteristics
II. RELATED WOEK
Several implementations of finding response time of
Real-Time System exist. Also there are several
implementations of performance analysis of IoT based
Health Care Monitoring for Real-Time System. Also
there are novel implementations of Signal Quality
Aware ECG Telemetry System for continuous
health monitoring applications. A brief survey’s
mentioned as below-
Udit Satija, [2016] proposes a novel signal quality
aware IoT-enabled ECG telemetry system for
continuous cardiac health monitoring applications.
The main purpose of these system is design and
development of light weight ECG signal quality
assessment method for automatically classifying the
acquired ECG signal into acceptable or unacceptable
class and real time implementation of proposed IoT
enabled ECG monitoring framework.[1]
R.Harini1, [2015] ECG is identify heart condition in
the rural underserved population where the doctor
patient ratio is low and access to health care is
difficult. The purpose of these system was clinical
validation of handheld ECG as a screening tool
evolution of cardiac diseases in the rural population.
[9]
B. Khaleelu Rehman1, [2017] The methodology of
ECG FIR filter based on FPGA. The ECG signal is
processed and implemented on FPGA platform. The
filtered signal is subject to short time Fourier
Transform by medical experts. A implication can be
made by medical experts. A recorded ECG signal is
used as test input and to test the implemented modules
on FPGA. [5]
Sande Seema, [2010] propsed the de-noising of ECG
signal also design algorithm for IIR and FIR filter in
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
ECG signal Characteristics
sponse time of
Time System exist. Also there are several
implementations of performance analysis of IoT based
Time System. Also
there are novel implementations of Signal Quality
Aware ECG Telemetry System for continuous cardiac
health monitoring applications. A brief survey’s
proposes a novel signal quality
enabled ECG telemetry system for
continuous cardiac health monitoring applications.
system is design and
development of light weight ECG signal quality
assessment method for automatically classifying the
acquired ECG signal into acceptable or unacceptable
class and real time implementation of proposed IoT
[1]
ECG is identify heart condition in
the rural underserved population where the doctor
patient ratio is low and access to health care is
difficult. The purpose of these system was clinical
validation of handheld ECG as a screening tool for
evolution of cardiac diseases in the rural population.
The methodology of
ECG FIR filter based on FPGA. The ECG signal is
processed and implemented on FPGA platform. The
filtered signal is subject to short time Fourier
Transform by medical experts. A implication can be
made by medical experts. A recorded ECG signal is
used as test input and to test the implemented modules
noising of ECG
R and FIR filter in
MATLAB environment to de
test the designed algorithm on modelsim these signal
transfer digital filter algorithm on FPGA plateform
and to analyze the complexity and accuracy of digital
filter on MATLAB.[15]
P. Girish, B .V .Ramana, [2014]
monitoring system featuring HEV analysis and
wireless data transmission through radio frequency
based on a SoC development platform. In this system
modelsim Xillinx Edition and Xillinx ISE will be used
simulation and synthesis respectively. The Xilinx
chip-scope tool will be used to test the FPGA inside
result while the logic running on FPGA. [11]
Yongming Yang, [2007] A real time ECG monitoring
system is proposed based on FPGA. The FPGA chip
is taken as the centrol microprocessor and applies
structured design on VHDL to collect and transmit
real-time ECG signals. It contain low power
consumption to carry around and long usage time.
The digital filtering and data compression arithmetic
are also integrated in the FPGA
improved or added with some other modules with
software modification. It is more intelligent compared
with existing portable ECG monitoring system. [20]
III. BLOCK DIAGRAM
The system is used to monitor ECG. Data is digitized
with an FPGA microcontroller and send to a
computer. The system s portable and runs on less
power. The system improves the quality of patient
monitoring and eliminates the need for nurses to
repeatedly manually perform these
Fig.2- Block diagram of FPGA
monitoring system.
A] FPGA-
A field-programmable gate array (FPGA) is an
integrated circuit designed to be configured by the
customer or designer after manufacturing, hence
"field-programmable". The FPGA configuration is
generally specified using a hardware description
language (HDL), similar to that used for an
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 217
MATLAB environment to de-noise ECG signal and
test the designed algorithm on modelsim these signal
transfer digital filter algorithm on FPGA plateform
and to analyze the complexity and accuracy of digital
[2014] A real time ECG
monitoring system featuring HEV analysis and
wireless data transmission through radio frequency
based on a SoC development platform. In this system
modelsim Xillinx Edition and Xillinx ISE will be used
synthesis respectively. The Xilinx
scope tool will be used to test the FPGA inside
result while the logic running on FPGA. [11]
A real time ECG monitoring
system is proposed based on FPGA. The FPGA chip
microprocessor and applies
structured design on VHDL to collect and transmit
time ECG signals. It contain low power
consumption to carry around and long usage time.
The digital filtering and data compression arithmetic
are also integrated in the FPGA chip and can be
or added with some other modules with
software modification. It is more intelligent compared
with existing portable ECG monitoring system. [20]
The system is used to monitor ECG. Data is digitized
microcontroller and send to a
computer. The system s portable and runs on less
power. The system improves the quality of patient
monitoring and eliminates the need for nurses to
ally perform these measurement.
Block diagram of FPGA based ECG patient
monitoring system.
programmable gate array (FPGA) is an
integrated circuit designed to be configured by the
customer or designer after manufacturing, hence
programmable". The FPGA configuration is
fied using a hardware description
language (HDL), similar to that used for an
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
application-specific integrated circuit (ASIC) FPGAs
can be used to implement any logical function that an
ASIC could perform.
The ability to update the functionality after ship
partial of the portion of the design and the low non
recurring engineering costs relative to an ASIC design
(notwithstanding the generally higher unit cost), offer
advantages for many applications. FPGAs contain
programmable logic components called "
blocks", and a hierarchy of reconfigurable
interconnects that allow the blocks to be "wired
together" somewhat like many (changeable) logic
gates that can be inter-wired in (many) different
configurations. Logic blocks can be configured to
perform complex combinational functions, or merely
simple logic gates like AND and XOR. The Spartan
family of Field Programmable Gate Array specifically
designed to meet the needs of high volume cost
sensitive consumer electronic.
B] ECG Sensor-
The AD8232 is an integrated signal conditioning
block for ECG and other bio potential measurement
applications. It is designed to extract, amplify, and
filter small bio potential signals in the presence of
noisy conditions, such as those created by motion or
remote electrode placement. This design allows for an
ultra-low power analog-to-digital converter (ADC) or
an embedded microcontroller to acquire the output
signal easily.
C] ADC-
An analog-to-digital converter (ADC, A/D, or
D) is a system that converts an analog signal
a sound picked up by a microphone or light entering
a digital camera, into a digital signal. An ADC may
also provide an isolated measurement such
an electronic device that converts an input
analog voltage or current to a digital number
representing the magnitude of the voltage or current.
Typically the digital output is a
complement binary number that is proportional to the
input, but there are other possibilities.
D] RS232-
RS 232 is a serial communication cable used in the
system. Here, the RS 232 provides the serial
communication between the microcontroller and the
outside world such as display, PC or Mobile etc. So
1it is a media used to communicate between
microcontroller and the PC. In our system the RS232
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
circuit (ASIC) FPGAs
can be used to implement any logical function that an
The ability to update the functionality after shipping,
partial of the portion of the design and the low non-
recurring engineering costs relative to an ASIC design
(notwithstanding the generally higher unit cost), offer
advantages for many applications. FPGAs contain
programmable logic components called "logic
blocks", and a hierarchy of reconfigurable
interconnects that allow the blocks to be "wired
together" somewhat like many (changeable) logic
wired in (many) different
configurations. Logic blocks can be configured to
mplex combinational functions, or merely
simple logic gates like AND and XOR. The Spartan-6
family of Field Programmable Gate Array specifically
designed to meet the needs of high volume cost-
an integrated signal conditioning
block for ECG and other bio potential measurement
applications. It is designed to extract, amplify, and
filter small bio potential signals in the presence of
noisy conditions, such as those created by motion or
ctrode placement. This design allows for an
digital converter (ADC) or
an embedded microcontroller to acquire the output
A/D, or A-to-
analog signal, such as
or light entering
. An ADC may
also provide an isolated measurement such as
that converts an input
to a digital number
representing the magnitude of the voltage or current.
Typically the digital output is a two's
binary number that is proportional to the
RS 232 is a serial communication cable used in the
system. Here, the RS 232 provides the serial
communication between the microcontroller and the
outside world such as display, PC or Mobile etc. So
1it is a media used to communicate between
and the PC. In our system the RS232
serves the function to transfer the data in between PC
and the FPGA, for the further operation of the system
E] COMPUTER /PC-
Computer / PC is used in a project to visualize the
output of the application. Computer / PC
for the Electrocardiography. A waveform of ECG can
be visualize on Computer /PC.
IV. PROPOSED METHODOLOGY
A] For IOT Framework –
The main modules of signal quality
framework are illustrated in Fig. It consists of three
modules: (i) ECG signal sensing module, (ii)
automated signal quality assessment module, and (iii)
signal-quality aware ECG analysis and transmission
module.
Fig.- 3 Signal Quality-
The main focus on design and real
implementation of automated ECG signal quality
assessment method and validation of the effectiveness
of the proposed SQA-IoT framework under resting,
ambulatory and physical activity conditions,
proposed automated ECG signal quality assessment
(ECG-SQA) method consists
flat-line (or ECG signal absence) detection, abrupt
baseline wander extraction, and high
detection and extraction to compute the signal quality
index (SQI) for assessing the clinical acceptability of
ECG signals. In this work, the ECG
implemented based on the-based filtering, turning
points and decision rules.
I] HF Noise Detection –
The high frequency (HF) noises such as muscle
artifacts, power line interference, motion artifacts,
pause and instrument noise ar
acquired ECG signal. Apply decision rules for
detecting the ECG segment with HF noises
where R1 is true if a total number of turning points in
any block (tpk) exceeds 5% of the number of samples
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 218
serves the function to transfer the data in between PC
and the FPGA, for the further operation of the system
Computer / PC is used in a project to visualize the
output of the application. Computer / PC is interfaced
for the Electrocardiography. A waveform of ECG can
be visualize on Computer /PC.
PROPOSED METHODOLOGY
The main modules of signal quality-aware (SQA)-IoT
framework are illustrated in Fig. It consists of three
ules: (i) ECG signal sensing module, (ii)
automated signal quality assessment module, and (iii)
quality aware ECG analysis and transmission
-aware framework
The main focus on design and real-time
automated ECG signal quality
assessment method and validation of the effectiveness
IoT framework under resting,
nd physical activity conditions, The
proposed automated ECG signal quality assessment
SQA) method consists of three steps such as
line (or ECG signal absence) detection, abrupt
baseline wander extraction, and high-frequency noise
detection and extraction to compute the signal quality
index (SQI) for assessing the clinical acceptability of
his work, the ECG-SQA is
based filtering, turning
The high frequency (HF) noises such as muscle
artifacts, power line interference, motion artifacts,
pause and instrument noise are introduced in the
acquired ECG signal. Apply decision rules for
detecting the ECG segment with HF noises-
where R1 is true if a total number of turning points in
) exceeds 5% of the number of samples
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
(P ∗ F s, where, F s is the sampling frequency of the
signal) in that block and R2 is true if the distance
between two turning points rk is less than two.
If SQIHF = 1 then the segment is classified as a HF
noise segment. Otherwise the segment is classified as
a high frequency noise-free ECG segment.
II] ECG signal absence detection-
Due to the disconnection of electrodes with skin and
the electronic component saturation, sensing device
exhibits the absence of ECG signal information in the
acquired signal. In practice, observation to the
recording shows the presence of zero amplitude flat
line (ZFL), only baseline wander (OBW), and the
long pause with physiological and external noises.
Existing approaches were developed for detection of
ZFL event. It is based on turning poin
can be computed as mentioned in Algorithm.
If SQIFL = 1 then the segment is classified as a flat
line or ECG signal absence segment. Otherwise the
segment is further processed for detecting the
presence of high frequency noises.
III] Abrupt Change Detection-
The ECG signals are corrupted by baseline wanders
that are mainly caused by respiratory activity, body
movements, skin-electrode interface, varying
impedance between electrodes and skin due to poor
electrode contact.
By using FIR Based –The basic structure of FIR filter
is like a sub-section of the delay lines. Each section of
the output of the weighted cumulative, the FIR
coefficient is-
y(nT).
= . ℎ(𝑘) 𝑥(𝑛 − 𝑘
The baseline wander signal is obtained as
b[n] = x[n] - x~ [n]
Where b (n) is the baseline wander signal and
is the baseline wander removed signal which is
computed as
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
is the sampling frequency of the
signal) in that block and R2 is true if the distance
is less than two.
If SQIHF = 1 then the segment is classified as a HF
noise segment. Otherwise the segment is classified as
free ECG segment.
Due to the disconnection of electrodes with skin and
the electronic component saturation, sensing device
exhibits the absence of ECG signal information in the
rvation to the
recording shows the presence of zero amplitude flat
line (ZFL), only baseline wander (OBW), and the
long pause with physiological and external noises.
Existing approaches were developed for detection of
ZFL event. It is based on turning points (TP) which
can be computed as mentioned in Algorithm.
If SQIFL = 1 then the segment is classified as a flat
line or ECG signal absence segment. Otherwise the
segment is further processed for detecting the
The ECG signals are corrupted by baseline wanders
that are mainly caused by respiratory activity, body
electrode interface, varying
impedance between electrodes and skin due to poor
The basic structure of FIR filter
section of the delay lines. Each section of
the output of the weighted cumulative, the FIR
𝑘)
The baseline wander signal is obtained as-
) is the baseline wander signal and x~ (n)
is the baseline wander removed signal which is
The detection decision rule is given by
Where SQIABW denotes the signal quality index
(SQI) for the presence of abrupt baseline drift (ABW)
event. Here, the γ is chosen as 0
abrupt baseline wander which can distort the ST
segment and other low-frequency components of the
ECG signal. The ECG signal with abrupt baseline
wander event is classified as an
ECG signal with slowly varying baseline wander is
classified as an acceptable since it can be removed
from the signal without significantly distorting the
PQRST complexes.
IV] ECG Signal Quality Grading
The grading of acquired ECG signal based on the
decision scores obtained for the detection of abrupt
baseline wander, ECG signal absence, and high
frequency noises. The ECG signal is graded with
three classes such as Good, Intermediate and bad
based on the HF noise score. The presence of flat line
and abrupt baseline wander may result in noisy
clinical features. Based upon assessment results, it is
noted that the some morphological features and RR
intervals can be measured from the ECG signal with
some level of HF noises. Thus, we grade the noisy
ECG signal into intermediate
γH is chosen as 0.1% of the maxima or minima in the
HF noise detection stage for detecting severe noise or
bad quality signal. While the noise level threshold
is set to 0.05% of the maxima or minima for grading
the noisy signal into intermediate
Where overall signal quality index (SQI) is computed
as
SQI = SQIABW + SQIFL + SQIHF
Good quality indicates the ECG signal with
acceptable level of noise which does not distort the
morphological features while
indicate the medium and high level of noise or poor
quality, respectively. The intermediate class of ECG
signals may be considered for application
ECG signal analysis systems.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 219
The detection decision rule is given by-
SQIABW denotes the signal quality index
(SQI) for the presence of abrupt baseline drift (ABW)
is chosen as 0:2 mV for detecting
abrupt baseline wander which can distort the ST
frequency components of the
. The ECG signal with abrupt baseline
wander event is classified as an unacceptable. The
ECG signal with slowly varying baseline wander is
since it can be removed
from the signal without significantly distorting the
IV] ECG Signal Quality Grading-
The grading of acquired ECG signal based on the
decision scores obtained for the detection of abrupt
baseline wander, ECG signal absence, and high
frequency noises. The ECG signal is graded with
ood, Intermediate and bad
based on the HF noise score. The presence of flat line
and abrupt baseline wander may result in noisy
clinical features. Based upon assessment results, it is
noted that the some morphological features and RR
red from the ECG signal with
some level of HF noises. Thus, we grade the noisy
intermediate and bad. The value of
is chosen as 0.1% of the maxima or minima in the
HF noise detection stage for detecting severe noise or
While the noise level threshold γH
is set to 0.05% of the maxima or minima for grading
intermediate class.
overall signal quality index (SQI) is computed
SQI = SQIABW + SQIFL + SQIHF
Good quality indicates the ECG signal with
acceptable level of noise which does not distort the
morphological features while intermediate and bad
indicate the medium and high level of noise or poor
quality, respectively. The intermediate class of ECG
ls may be considered for application-specific
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
B] For Androd Application-
 ALGORITHM-
1. Initialize central processing unit
2. Initialize Ports
3. Initialize memory
4. Initialize ADC
5. Connect 3-leads of electrode in correct place
6. Read the signals from the sensor and transmit
signals to the amplifier
7. Convert analog signal to digital signal u
ADC3204
8. Display the ECG signal on PC
9. Also display on Android phone
V. SYSTEM IMPIMENTATON
A] Software Implementation
1.1 Mit-Bih Database
The dataset used in this study is obtained from
Physiobank entitled MIT-BIH Arrhythmia Database
available on-line. MIT-BIH Arrhythmia Database
which having sources of ECGs includes set of over
4000 long-term Holter recorders, which was obtain
from Beth Israel Hospital Arrhythmia Laboratory.
Each signal is recorded with 360 sampling frequency
which having 11-bit resolution with 10 mv range.
MIT-BIH Arrhythmia Database where annotated ECG
signals are described by a text header file (.hea), a
binary file (.dat) and a binary annotated file (.atr).
Header file consists of detailed information such as
number of samples, sampling frequency, format of
ECG signal, type and number of ECG leads, patient’s
history and the detailed clinical information. In binar
data signal file, the signal is stored in 212 format
which means each sample requires number of lead
times 12 bits to be stored and the binary annotation
file consists of beat annotation from which
database has been freely available .For EMG
is obtained from MIT-BIH Noise stress database from
PhysioBank. Noise stress database includes 12 half
hour ECG recordings and 3 half-hour recordings. This
is having a noise typical in ambulatory ECG
recordings. PhysioBank noise recordings were taken
by physical activities of volunteers. For ECG
recording 3 noise records were assembled. These
recordings were contain predominantly baseline
wander (as 'bw'), muscle artifact (as 'ma') which also
known as EMG noise and third one is electrode
motion artifact (as 'em'). From noise stress database
records of ‘bw’ contains primarily baseline wander
with low frequency signals, which was caused by
motion of the volunteer or the leads. Recorded ECG
‘em’ contains electrode motion artifacts with
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
electrode in correct place
Read the signals from the sensor and transmit
tal signal using
The dataset used in this study is obtained from
BIH Arrhythmia Database
BIH Arrhythmia Database
which having sources of ECGs includes set of over
term Holter recorders, which was obtain
Beth Israel Hospital Arrhythmia Laboratory.
Each signal is recorded with 360 sampling frequency
bit resolution with 10 mv range.
BIH Arrhythmia Database where annotated ECG
signals are described by a text header file (.hea), a
ile (.dat) and a binary annotated file (.atr).
Header file consists of detailed information such as
number of samples, sampling frequency, format of
ECG signal, type and number of ECG leads, patient’s
history and the detailed clinical information. In binary
data signal file, the signal is stored in 212 format
which means each sample requires number of lead
times 12 bits to be stored and the binary annotation
file consists of beat annotation from which half of this
For EMG dataset
BIH Noise stress database from
Noise stress database includes 12 half-
hour recordings. This
is having a noise typical in ambulatory ECG
recordings. PhysioBank noise recordings were taken
by physical activities of volunteers. For ECG
ds were assembled. These
recordings were contain predominantly baseline
wander (as 'bw'), muscle artifact (as 'ma') which also
known as EMG noise and third one is electrode
motion artifact (as 'em'). From noise stress database
arily baseline wander
with low frequency signals, which was caused by
motion of the volunteer or the leads. Recorded ECG
‘em’ contains electrode motion artifacts with
significant amounts of muscle noise and baseline
wander. Recorded ECG ‘ma’ contains prima
muscle noise (EMG) with spectrum, which overlaps
that of the ECG, which extends to higher frequency.
1.2 MATLAB
MATLAB is a powerful, comprehensive, and easy to
use environment for technical computations,
greatest strengths is that MATLAB
own reusable tools. Mat lab
database extraction which is stored at
www.physiobank.org. Stored ECG signal can be
called in Simulink model from workspace of
Real time EMG noise is accessed from MIT
noise stress database in the form of .mat file then it is
imported into workspace which is added with pure
ECG in Simulink model. For designing of FIR low
pass filter FDA Tool from MATLAB
Different types of FIR digital filter designed to
remove high frequency EMG noise.
1.3 FIR FILTER
FIR filters are widely used because of inherent
stability and due to the powerful design algorithms
which are exist from them. When FIR filters
implement in non-recursive f
can obtain with ease. FIR low pass filter is designed
by equiripple filtering, least square method,
windowing method for designing have been used. In
windowing method such as Kaiser, Rectangular,
Hamming, Hanning and Blackman function
designed.
1.4 Flow chart for MATLAB programming
1.5 Simulink model for F
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 220
significant amounts of muscle noise and baseline
wander. Recorded ECG ‘ma’ contains primarily
muscle noise (EMG) with spectrum, which overlaps
that of the ECG, which extends to higher frequency.
is a powerful, comprehensive, and easy to
ment for technical computations, one of its
greatest strengths is that MATLAB allows building its
is being used for ECG
database extraction which is stored at
. Stored ECG signal can be
called in Simulink model from workspace of mat lab.
EMG noise is accessed from MIT-BIH
noise stress database in the form of .mat file then it is
imported into workspace which is added with pure
ECG in Simulink model. For designing of FIR low
Tool from MATLAB has been used.
of FIR digital filter designed to
remove high frequency EMG noise.
FIR filters are widely used because of inherent
stability and due to the powerful design algorithms
which are exist from them. When FIR filters
recursive form, linear phase one
can obtain with ease. FIR low pass filter is designed
by equiripple filtering, least square method,
windowing method for designing have been used. In
windowing method such as Kaiser, Rectangular,
Hamming, Hanning and Blackman functions are
ow chart for MATLAB programming
1.5 Simulink model for FIR filter
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Fig4- Simulink Model of ECG De
In above fig-4 it show that the design of
The filters are designed using MATLAB FDA Tool
by specifying the filter order, cut off frequency and
sampling frequency. In the present section, the design
considerations of low pass filter, high pass filter,
notch filter are elaborated separately for
noise signals from ECG using FIR filter. For ECG de
noising the digital filter is designed with various
orders. Output of this various designs are simulated
and analyzed with the help of performance parameters
like SNR and MSE.
B] HARDWARE IMPLEMENTATION
The implementation of the design is fundamental to
move from software to a hardware realization. The
implementation technique exploits the parallel
structure and the versatility of Field Programmable
Gate Arrays (FPGAs) in order to yield a high
performance and yet low cost implementation.
The step by step procedures that are used to complete
this project are highlighted. They are explained in
below. The explanations are important in complete the
objectives of the project. As shown in below flow
chart, the implementation procedure will be followed.
The board at transmitter side will be FPGA board and
at the receiver side the board will be Bluetooth model
and Arduino in this digital hardware system.
Fig5-Experimental setup of telemetry system
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
imulink Model of ECG De-noising
4 it show that the design of FIR filter.
designed using MATLAB FDA Tool
order, cut off frequency and
sampling frequency. In the present section, the design
high pass filter,
notch filter are elaborated separately for removal of
R filter. For ECG de-
g the digital filter is designed with various
orders. Output of this various designs are simulated
and analyzed with the help of performance parameters
IMPLEMENTATION
The implementation of the design is fundamental to
move from software to a hardware realization. The
implementation technique exploits the parallel
structure and the versatility of Field Programmable
Gate Arrays (FPGAs) in order to yield a high
performance and yet low cost implementation.
step procedures that are used to complete
this project are highlighted. They are explained in
below. The explanations are important in complete the
objectives of the project. As shown in below flow
chart, the implementation procedure will be followed.
board at transmitter side will be FPGA board and
at the receiver side the board will be Bluetooth model
and Arduino in this digital hardware system.
try system
FLOW CHART
The experimental setup of the system which includes
FPGA board, ECG sensor, Arduino
ECG waveform display on mon
applicatonis given in below figure:
Fig 6-Experimental setup of system
VI. RESULT AND DISCUSSION
I] Matlab Simulation Result
Clean ECG is taken from MIT
with low frequency noise. Simulation was done on
SIMULINK available with MATLAB. Fig.7shows
pure ECG from MIT-BIH Arrhythmia database of
patient shows noisy ECG. Fig.
of different FIR filter methods on low frequency
EMG noise. Equation (1) is used to calculate SNR of
filtered signal and mean square error (MSE) from
equation (2) is calculated.
N ∑ (ECG raw) 2
SNR= 10 log10
N∑ (ECG raw – ECG filtered) 2 i=
N∑ (ECG raw – ECG filtered)2
MSE =
N
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 221
FLOW CHART
The experimental setup of the system which includes
Arduino& Bluetooth, the
display on monitor and Android
is given in below figure:
Experimental setup of system
DISCUSSION
Clean ECG is taken from MIT-BIH which is added
Simulation was done on
SIMULINK available with MATLAB. Fig.7shows
BIH Arrhythmia database of
patient shows noisy ECG. Fig.8shows the application
of different FIR filter methods on low frequency
EMG noise. Equation (1) is used to calculate SNR of
filtered signal and mean square error (MSE) from
SNR= 10 log10 i=0
----- (1)
MSE = i=0
N -----(2)
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Fig 7- Noisy ECG Signal
Fig 8-Filtered ECG Signal
Types and
order of the
FIR Filter
ECG
Sample
SNR
in dB
Mean
Error
Blackman low
pass filter (100)
Ecg24 19.21
Hamming low
pass filter (100)
Ecg24 19.20
Hanning low
pass filter (100)
Ecg24 19.21
Kaiser low pass
filter (100)
Ecg24 18.67
Rectangular low
pass filter (100)
Ecg24 19.11
Table 1 - Performances and evaluation of FIR low
pass filters on MIT-BIH database.
The value shows SNR in dB.
In Table 1 comparison of different FIR method for
SNR and MSE is given. Here it can be concluded that
FIR method effectively remove the EMG nois
without distortion of the ECG signal. In case of
Equiripple, Hamming, Hanning order of the filter was
increased which increases the complexity of filter
designing. So that SNR of FIR filter with Kaiser is
(18.67) less than other type of filter. In case o
method the order of the filter easily grow very much
.It increases the number of filter coefficient which
leads to the large memory requirement and problems
in hardware implementation.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
Filtered ECG Signal
Mean Square
Error (MSE)
25.67
25.67
25.67
25.42
25.62
Performances and evaluation of FIR low
BIH database.
The value shows SNR in dB.
In Table 1 comparison of different FIR method for
SNR and MSE is given. Here it can be concluded that
FIR method effectively remove the EMG noise
without distortion of the ECG signal. In case of
Equiripple, Hamming, Hanning order of the filter was
increased which increases the complexity of filter
designing. So that SNR of FIR filter with Kaiser is
(18.67) less than other type of filter. In case of other
method the order of the filter easily grow very much
.It increases the number of filter coefficient which
leads to the large memory requirement and problems
B] Hardware Implementation Result
I] Waveform Analysis-
The output waveforms generated by FIR filter give
better filtered output. The output waveforms are
generated with normal ECG signal
signal, filtered low pass signal and peak detection as
shown in fig.9 below
Fig.9- De-noising ECG Signal
Spartan Hardware kit.
When the real time ECG signal display on the PC then
at time it display on the android application. The ECG
output waveforms display on the Android phone as
shown in fig. 10 –
Fig. 10- ECG waveform display o
applicaton.
II] DEVICE UTILIZATION SUMMARY
AND POWER ANALYSIS
a) Device Utilization-
After implementation on Spartan FPGA kit,
utilization of resources i.e. no of LUTs, Slices,
Bonded I/O has been calculated for different types of
FIR filter. Fig. 11- shows that Equiripple requires
highest no. of slices, flip-flop,4 input LUTs, bonded
IOB with 1GCLK. In window method Kaiser has
minimum utilization of resources. As it require 87
slices, 156 slices, Flip flop, 111 LUTs, 17 bonded
IOB, with 1 GCLK.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 222
Hardware Implementation Results
output waveforms generated by FIR filter give
better filtered output. The output waveforms are
generated with normal ECG signal, filtered high pass
filtered low pass signal and peak detection as
noising ECG Signal by FIR Filter by using
Hardware kit.
When the real time ECG signal display on the PC then
at time it display on the android application. The ECG
output waveforms display on the Android phone as
ECG waveform display on Android
applicaton.
DEVICE UTILIZATION SUMMARY
AND POWER ANALYSIS-
After implementation on Spartan FPGA kit,
utilization of resources i.e. no of LUTs, Slices,
Bonded I/O has been calculated for different types of
shows that Equiripple requires
flop,4 input LUTs, bonded
IOB with 1GCLK. In window method Kaiser has
minimum utilization of resources. As it require 87
Flip flop, 111 LUTs, 17 bonded
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Fig.11- Device Utilization Report of FIR Filter
b) Power analysis-
Power analysis will generate the timing, ISE report
and power utilization report for the particular design.
Snapshots of Power Analyzer for FIR filter shown in
Fig. 12-
Fig.12- Device Utilization Report of FIR Filter
VII. CONCLUSON
In this research paper, the implementation of FIR
filter on FPGA has been introduced. It has been
investigated that, the improvement of noisy ECG
signals can be achieved by combination of FIR
In order to measure the performance of de
SNR of processed ECG is calculated and MSE was
determined to find the degree of mismatch between
noisy ECG and filtered. The designed FIR filter with
Kaiser Window works excellent in removing High
frequency interference from noisy ECG conditions
utilizing low order of filter. Utilization of resources
using FIR filter has been minimizedi.
consumption (74mw)and minted the quality of ECG
signal.
This method is more applicable in variou
applications of ECG monitoring. Use of optimization
technique using FPGA platform will improve the
quality and processing time. FPGA are finding wide
acceptance in medical system. For their ability for
rapid prototyping of a concept that requires
hardware/software co-design, for performing custom
processing in parallel at high data rates.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
Device Utilization Report of FIR Filter
Power analysis will generate the timing, ISE report
and power utilization report for the particular design.
Snapshots of Power Analyzer for FIR filter shown in
tilization Report of FIR Filter
In this research paper, the implementation of FIR
filter on FPGA has been introduced. It has been
investigated that, the improvement of noisy ECG
signals can be achieved by combination of FIR filters.
In order to measure the performance of de-noising,
SNR of processed ECG is calculated and MSE was
determined to find the degree of mismatch between
noisy ECG and filtered. The designed FIR filter with
Kaiser Window works excellent in removing High
frequency interference from noisy ECG conditions
utilizing low order of filter. Utilization of resources
e. less power
and minted the quality of ECG
This method is more applicable in various
Use of optimization
technique using FPGA platform will improve the
quality and processing time. FPGA are finding wide
acceptance in medical system. For their ability for
rapid prototyping of a concept that requires
design, for performing custom
processing in parallel at high data rates.
VIII. FUTURE SCOPE
The implementation of FIR High Pass filter
techniques gives better results on higher end FPGA
devices like Virtex, which are having more
and facilities than Spartan devices.
be successfully applied with the cascading of IIR and
FIR filters for real time ECG systems. Finally, it is
seen that an optimum combination can be
implemented using FPGA technique.
IX.REFERANCES
1. Yongming Yang I, Xiaobo Huang 1, Xinghuo Yu,
“Real-Time ECG Monitoring System Based on
FPGA ”, The 33rd Annual Conference of the
IEEE Industrial Electronics Society (IECON)
Nov. 5-8, 2007.
2. Borromeo S, Rodriguez-Sanchez C, Machado F,
Hernandez-Tamames JA, de la Prieta R.
Reconfigurable, Wearable, Wireless ECG System
”, the 29th Annual International Conference of the
IEEE EMBS Cité Internationale, Lyon, France
August 23-26, 2007.
3. Brian A. Walker#, Ahsan H. Khandoker#, and Jim
Black, “Low Cost ECG Monit
Countries” , 2009
4. ndrej Krejcar, Dalibor Janckulik, Leona Motalova,
Karel Musi, “Real Time Processing of ECG
Signal on Mobile Embedded Monitoring Stations
”, Second International Conference on Computer
Engineering and Applications, 2010.
5. Ankit J. Gordhandas and
George C. Verghese, “Real
Analysis of Key Morphological Features in the
Electrocardiogram, for Data Compression and
Clinical Decision Support”,
6. Abhilasha M. Patel, Pankaj K. Gakare, A.
Cheeran, “Real Time ECG Feature Extraction and
Arrhythmia Detection on a Mobile Platform
International Journal of Computer Applications
(0975 – 8887) Volume 44–
7. Sonal K. Jagtap, Research Student
Approach: ECG Noise Red
Type II Digital Filter”, International Journal of
Computer Applications (0975
49– No.9, July 2012.
8. Sayanti Chattopadhyay1, Susmita Das2, Avishek
Nag3, Jayanta Kumar Ray4, Soumyendu
Bhattacharjee5, Dr. Biswarup Neogi, “Des
Simulation Approach Introduced to ECG Peak
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 223
The implementation of FIR High Pass filter
techniques gives better results on higher end FPGA
devices like Virtex, which are having more resources
and facilities than Spartan devices. This method can
be successfully applied with the cascading of IIR and
FIR filters for real time ECG systems. Finally, it is
seen that an optimum combination can be
implemented using FPGA technique.
Yongming Yang I, Xiaobo Huang 1, Xinghuo Yu,
Time ECG Monitoring System Based on
FPGA ”, The 33rd Annual Conference of the
IEEE Industrial Electronics Society (IECON)
Sanchez C, Machado F,
A, de la Prieta R. “A
Reconfigurable, Wearable, Wireless ECG System
the 29th Annual International Conference of the
IEEE EMBS Cité Internationale, Lyon, France
Brian A. Walker#, Ahsan H. Khandoker#, and Jim
Black, “Low Cost ECG Monitor for Developing
ndrej Krejcar, Dalibor Janckulik, Leona Motalova,
Real Time Processing of ECG
Signal on Mobile Embedded Monitoring Stations
”, Second International Conference on Computer
Engineering and Applications, 2010.
and Thomas Heldt and
Real-Time Extraction and
Analysis of Key Morphological Features in the
Electrocardiogram, for Data Compression and
Clinical Decision Support”, AAAI 2011.
Abhilasha M. Patel, Pankaj K. Gakare, A. N.
Real Time ECG Feature Extraction and
Arrhythmia Detection on a Mobile Platform”,
International Journal of Computer Applications
– No.23, April 2012
Sonal K. Jagtap, Research Student, “A Real Time
Approach: ECG Noise Reduction in Chebyshev
International Journal of
Computer Applications (0975 – 8887) Volume
Sayanti Chattopadhyay1, Susmita Das2, Avishek
Nag3, Jayanta Kumar Ray4, Soumyendu
Bhattacharjee5, Dr. Biswarup Neogi, “Design and
Simulation Approach Introduced to ECG Peak
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
@ IJTSRD | Available Online @ www.ijtsrd.com
Detection with Study on Different Cardiovascular
Diseases”, December 2012.
9. Masudul Haider Imtiaz & Md. Adnan Kiber,
“Design and Implementation of a Real
Automated ECG
Diagnosis (AED) System”, 2013
10. Bhushan N. Patil, “A Review of ECG Monitoring
System Using Wavelet Transform”
Journal of Research in Advent Technology, Vol.2,
No.4, April 2014.
11. Prerana N Gawale1, A N Cheeran2, Nidhi G
Sharma, “Android Application for Ambulant ECG
Monitoring”, International Journal of Advanced
Research in Computer and Communication
Engineering
Vol. 3, Issue 5, May 2014.
12. Luca Catarinucci, Danilo De Donno, Luca
Mainetti, Luca Palano, Luigi Patrono, Maria
Laura
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456
www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018
Detection with Study on Different Cardiovascular
Masudul Haider Imtiaz & Md. Adnan Kiber,
“Design and Implementation of a Real-Time
Automated ECG
A Review of ECG Monitoring
System Using Wavelet Transform” International
Journal of Research in Advent Technology, Vol.2,
Prerana N Gawale1, A N Cheeran2, Nidhi G
Android Application for Ambulant ECG
International Journal of Advanced
Research in Computer and Communication
Luca Catarinucci, Danilo De Donno, Luca
Mainetti, Luca Palano, Luigi Patrono, Maria
Stefanizzi, and Luciano Tarricone, “An IoT
Aware Architecture for Smart Healthcare Systems
”, IEEE Internet of Things Journal, DOI
10.1109/JIOT.2015.
13. Sudip Deb, Sheikh Md. Rabiul Islam, Jannatul
RobaiatMou, Md. Tariqul Islam,” Design and
Implementation of Low Cost ECG Monitoring
System for the Patient u
February 16-18, 2017Feb 2017.
14. Udit Satija, Student Member,
Ramkumar, and M. Sabarimalai Manikandan,
Member, IEEE “Real-Time Signal Quality
ECG Telemetry System for IoT
Care Monitoring” IEEE Internet
Journal, DOI 10.1109/JIOT.2017.
15. R.Harini1, B. Rama Murthy2 , K.
“DEVELOPMENT OF ECG MONITORING
SYSTEM USING ANDROID APP ”, March
2017.
International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470
Dec 2018 Page: 224
Stefanizzi, and Luciano Tarricone, “An IoT-
Architecture for Smart Healthcare Systems
”, IEEE Internet of Things Journal, DOI
Sudip Deb, Sheikh Md. Rabiul Islam, Jannatul
Md. Tariqul Islam,” Design and
Implementation of Low Cost ECG Monitoring
System for the Patient using Smart Device”, ,
18, 2017Feb 2017.
Udit Satija, Student Member, IEEE, Barathram.
Ramkumar, and M. Sabarimalai Manikandan,
Time Signal Quality-Aware
ECG Telemetry System for IoT-Based Health
Care Monitoring” IEEE Internet of Things
DOI 10.1109/JIOT.2017.
R.Harini1, B. Rama Murthy2 , K. Tanveer Alam,
OPMENT OF ECG MONITORING
USING ANDROID APP ”, March

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Real Time Signal Quality Aware Internet of Things IOT Framework for FPGA Based ECG Telemetry System and Development of Android Application

  • 1. International Journal of Trend in International Open Access Journal ISSN No: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com Real Time Signal Quali Framework for FPGA Development o Dhanashri Department of Technology, ABSTRACT Day by day the scope & use of the electronics concepts in bio-medical field is increasing gradually. A novel approach to the design of real time ECG signal acquisition system for patient mo medical application, FPGA (Field Programmable Gate Array) is the core heart of proposed system which is configured and programmed to acquire using ECG (Electrocardiogram) sensor. In this paper a new concept of ECG telemetry system is discussed with signal quality aware IoT framework for energy efficient ECG monitoring system. Tele monitoring is a medical practice that involves monitoring patients who are not at the same location as the healthcare provider. The purpose of the present study identify heart condition and give the information to the doctor. The objective of the study is to improve the doctor-patient ratio and evaluation of cardiac diseases in the rural population. The proposed system for the electrocardiogram (ECG) mon controlled by FPGA and implemented in the form of android application. Keyword- FPGA (Field programmable gate array), Electrocardiogram (ECG) signals, IoT (Internet of Things) I. INTRODUCTION The word electrocardiography is evolved from Greek word Kardia which means Heart. ECG that is electrocardiography is a process of interpretation of heart activity over the period of time and is detected by electrodes attached to the surface of body. An ECG is used to measure the heart’s electrical conduction system. It picks up electrical impulses generated by the polarization and depolarization of cardiac tissue and translates into a waveform. The waveform is then used to measure the rate and regularity of International Journal of Trend in Scientific Research and Development (IJTSRD) International Open Access Journal | www.ijtsrd.com ISSN No: 2456 - 6470 | Volume - 3 | Issue – 1 | Nov www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 Signal Quality Aware Internet of Things (IOT) FPGA Based ECG Telemetry System and Development of Android Application Dhanashri P. Yamagekar, Dr. P. C. Bhaskar f Technology, Shivaji University Kolhapur, India Day by day the scope & use of the electronics medical field is increasing gradually. A novel approach to the design of real time ECG signal acquisition system for patient monitoring in FPGA (Field Programmable Gate Array) is the core heart of proposed system which is configured and programmed to acquire using ECG In this paper a new concept of ECG telemetry system is discussed along with signal quality aware IoT framework for energy efficient ECG monitoring system. Tele monitoring is a medical practice that involves monitoring patients who are not at the same location as the healthcare provider. The purpose of the present study is use to identify heart condition and give the information to the doctor. The objective of the study is to improve patient ratio and evaluation of cardiac diseases in the rural population. The proposed system for the electrocardiogram (ECG) monitoring controlled by FPGA and implemented in the form of FPGA (Field programmable gate array), Electrocardiogram (ECG) signals, IoT (Internet of The word electrocardiography is evolved from Greek word Kardia which means Heart. ECG that is electrocardiography is a process of interpretation of heart activity over the period of time and is detected by electrodes attached to the surface of body. An ECG is used to measure the heart’s electrical conduction system. It picks up electrical impulses generated by the polarization and depolarization of cardiac tissue and translates into a waveform. The waveform is then used to measure the rate and regularity of heartbeats, as well as the size and position of the chambers, the presence of any damage to the heart, and the effects of the drugs or devices used to regulate the heart, such as a pacemaker. A typical ECG tracing of normal heartbeat consists of a P wave, a QRS complex and a T wave. Data acquisition products server as a focal point in a system, tying together a wide variety of products such as sensor that indicate temperature, flow, levels, pulse rate, electrocardiograph etc. The core heart of the proposed system is field programmable gate array (FPGA) which is configured and programmed to acquire a real time data. Real time data from the process is acquired using ECG sensor. Signal conditioners are designed for each sensor. Signal conditioners are interfaced with FPGA through ADC and MAX 232 for PC interfacing. Output of the system is displayed waveform on PC. An electrocardiogram is a test that checks for problem with the electrical activity of our heart. An ECG translates the heart’s electrical act tracing on paper. The spikes and dips in the line tracing are called waves. The ECG signal consist of P, Q, R, S, T waves. The function of each wave is  P Wave- represents the atrial contraction  QRS complex represents the ventricular contraction.  R peaks- represents a heartbeat.  T wave- represent the last common wave in an ECG. The electrical signal is produced when the ventricles are repolarizing. Research and Development (IJTSRD) www.ijtsrd.com 1 | Nov – Dec 2018 Dec 2018 Page: 216 ty Aware Internet of Things (IOT) lemetry System and as well as the size and position of the chambers, the presence of any damage to the heart, and the effects of the drugs or devices used to regulate the heart, such as A typical ECG tracing of normal heartbeat consists of wave, a QRS complex and a T wave. Data acquisition products server as a focal point in a system, tying together a wide variety of products such as sensor that indicate temperature, flow, levels, pulse oposed system is field programmable gate array (FPGA) which is configured and programmed to acquire a real time data. Real time data from the process is acquired using ECG sensor. Signal conditioners are designed for each sensor. terfaced with FPGA through ADC and MAX 232 for PC interfacing. Output of the system is displayed waveform on PC. An electrocardiogram is a test that checks for problem with the electrical activity of our heart. An ECG translates the heart’s electrical activity into line tracing on paper. The spikes and dips in the line tracing are called waves. The ECG signal consist of P, Q, R, S, T waves. The function of each wave is- represents the atrial contraction QRS complex represents the ventricular represents a heartbeat. represent the last common wave in an ECG. The electrical signal is produced when the ventricles are repolarizing.
  • 2. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com Fig. 1- ECG signal Characteristics II. RELATED WOEK Several implementations of finding response time of Real-Time System exist. Also there are several implementations of performance analysis of IoT based Health Care Monitoring for Real-Time System. Also there are novel implementations of Signal Quality Aware ECG Telemetry System for continuous health monitoring applications. A brief survey’s mentioned as below- Udit Satija, [2016] proposes a novel signal quality aware IoT-enabled ECG telemetry system for continuous cardiac health monitoring applications. The main purpose of these system is design and development of light weight ECG signal quality assessment method for automatically classifying the acquired ECG signal into acceptable or unacceptable class and real time implementation of proposed IoT enabled ECG monitoring framework.[1] R.Harini1, [2015] ECG is identify heart condition in the rural underserved population where the doctor patient ratio is low and access to health care is difficult. The purpose of these system was clinical validation of handheld ECG as a screening tool evolution of cardiac diseases in the rural population. [9] B. Khaleelu Rehman1, [2017] The methodology of ECG FIR filter based on FPGA. The ECG signal is processed and implemented on FPGA platform. The filtered signal is subject to short time Fourier Transform by medical experts. A implication can be made by medical experts. A recorded ECG signal is used as test input and to test the implemented modules on FPGA. [5] Sande Seema, [2010] propsed the de-noising of ECG signal also design algorithm for IIR and FIR filter in International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 ECG signal Characteristics sponse time of Time System exist. Also there are several implementations of performance analysis of IoT based Time System. Also there are novel implementations of Signal Quality Aware ECG Telemetry System for continuous cardiac health monitoring applications. A brief survey’s proposes a novel signal quality enabled ECG telemetry system for continuous cardiac health monitoring applications. system is design and development of light weight ECG signal quality assessment method for automatically classifying the acquired ECG signal into acceptable or unacceptable class and real time implementation of proposed IoT [1] ECG is identify heart condition in the rural underserved population where the doctor patient ratio is low and access to health care is difficult. The purpose of these system was clinical validation of handheld ECG as a screening tool for evolution of cardiac diseases in the rural population. The methodology of ECG FIR filter based on FPGA. The ECG signal is processed and implemented on FPGA platform. The filtered signal is subject to short time Fourier Transform by medical experts. A implication can be made by medical experts. A recorded ECG signal is used as test input and to test the implemented modules noising of ECG R and FIR filter in MATLAB environment to de test the designed algorithm on modelsim these signal transfer digital filter algorithm on FPGA plateform and to analyze the complexity and accuracy of digital filter on MATLAB.[15] P. Girish, B .V .Ramana, [2014] monitoring system featuring HEV analysis and wireless data transmission through radio frequency based on a SoC development platform. In this system modelsim Xillinx Edition and Xillinx ISE will be used simulation and synthesis respectively. The Xilinx chip-scope tool will be used to test the FPGA inside result while the logic running on FPGA. [11] Yongming Yang, [2007] A real time ECG monitoring system is proposed based on FPGA. The FPGA chip is taken as the centrol microprocessor and applies structured design on VHDL to collect and transmit real-time ECG signals. It contain low power consumption to carry around and long usage time. The digital filtering and data compression arithmetic are also integrated in the FPGA improved or added with some other modules with software modification. It is more intelligent compared with existing portable ECG monitoring system. [20] III. BLOCK DIAGRAM The system is used to monitor ECG. Data is digitized with an FPGA microcontroller and send to a computer. The system s portable and runs on less power. The system improves the quality of patient monitoring and eliminates the need for nurses to repeatedly manually perform these Fig.2- Block diagram of FPGA monitoring system. A] FPGA- A field-programmable gate array (FPGA) is an integrated circuit designed to be configured by the customer or designer after manufacturing, hence "field-programmable". The FPGA configuration is generally specified using a hardware description language (HDL), similar to that used for an International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 217 MATLAB environment to de-noise ECG signal and test the designed algorithm on modelsim these signal transfer digital filter algorithm on FPGA plateform and to analyze the complexity and accuracy of digital [2014] A real time ECG monitoring system featuring HEV analysis and wireless data transmission through radio frequency based on a SoC development platform. In this system modelsim Xillinx Edition and Xillinx ISE will be used synthesis respectively. The Xilinx scope tool will be used to test the FPGA inside result while the logic running on FPGA. [11] A real time ECG monitoring system is proposed based on FPGA. The FPGA chip microprocessor and applies structured design on VHDL to collect and transmit time ECG signals. It contain low power consumption to carry around and long usage time. The digital filtering and data compression arithmetic are also integrated in the FPGA chip and can be or added with some other modules with software modification. It is more intelligent compared with existing portable ECG monitoring system. [20] The system is used to monitor ECG. Data is digitized microcontroller and send to a computer. The system s portable and runs on less power. The system improves the quality of patient monitoring and eliminates the need for nurses to ally perform these measurement. Block diagram of FPGA based ECG patient monitoring system. programmable gate array (FPGA) is an integrated circuit designed to be configured by the customer or designer after manufacturing, hence programmable". The FPGA configuration is fied using a hardware description language (HDL), similar to that used for an
  • 3. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com application-specific integrated circuit (ASIC) FPGAs can be used to implement any logical function that an ASIC could perform. The ability to update the functionality after ship partial of the portion of the design and the low non recurring engineering costs relative to an ASIC design (notwithstanding the generally higher unit cost), offer advantages for many applications. FPGAs contain programmable logic components called " blocks", and a hierarchy of reconfigurable interconnects that allow the blocks to be "wired together" somewhat like many (changeable) logic gates that can be inter-wired in (many) different configurations. Logic blocks can be configured to perform complex combinational functions, or merely simple logic gates like AND and XOR. The Spartan family of Field Programmable Gate Array specifically designed to meet the needs of high volume cost sensitive consumer electronic. B] ECG Sensor- The AD8232 is an integrated signal conditioning block for ECG and other bio potential measurement applications. It is designed to extract, amplify, and filter small bio potential signals in the presence of noisy conditions, such as those created by motion or remote electrode placement. This design allows for an ultra-low power analog-to-digital converter (ADC) or an embedded microcontroller to acquire the output signal easily. C] ADC- An analog-to-digital converter (ADC, A/D, or D) is a system that converts an analog signal a sound picked up by a microphone or light entering a digital camera, into a digital signal. An ADC may also provide an isolated measurement such an electronic device that converts an input analog voltage or current to a digital number representing the magnitude of the voltage or current. Typically the digital output is a complement binary number that is proportional to the input, but there are other possibilities. D] RS232- RS 232 is a serial communication cable used in the system. Here, the RS 232 provides the serial communication between the microcontroller and the outside world such as display, PC or Mobile etc. So 1it is a media used to communicate between microcontroller and the PC. In our system the RS232 International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 circuit (ASIC) FPGAs can be used to implement any logical function that an The ability to update the functionality after shipping, partial of the portion of the design and the low non- recurring engineering costs relative to an ASIC design (notwithstanding the generally higher unit cost), offer advantages for many applications. FPGAs contain programmable logic components called "logic blocks", and a hierarchy of reconfigurable interconnects that allow the blocks to be "wired together" somewhat like many (changeable) logic wired in (many) different configurations. Logic blocks can be configured to mplex combinational functions, or merely simple logic gates like AND and XOR. The Spartan-6 family of Field Programmable Gate Array specifically designed to meet the needs of high volume cost- an integrated signal conditioning block for ECG and other bio potential measurement applications. It is designed to extract, amplify, and filter small bio potential signals in the presence of noisy conditions, such as those created by motion or ctrode placement. This design allows for an digital converter (ADC) or an embedded microcontroller to acquire the output A/D, or A-to- analog signal, such as or light entering . An ADC may also provide an isolated measurement such as that converts an input to a digital number representing the magnitude of the voltage or current. Typically the digital output is a two's binary number that is proportional to the RS 232 is a serial communication cable used in the system. Here, the RS 232 provides the serial communication between the microcontroller and the outside world such as display, PC or Mobile etc. So 1it is a media used to communicate between and the PC. In our system the RS232 serves the function to transfer the data in between PC and the FPGA, for the further operation of the system E] COMPUTER /PC- Computer / PC is used in a project to visualize the output of the application. Computer / PC for the Electrocardiography. A waveform of ECG can be visualize on Computer /PC. IV. PROPOSED METHODOLOGY A] For IOT Framework – The main modules of signal quality framework are illustrated in Fig. It consists of three modules: (i) ECG signal sensing module, (ii) automated signal quality assessment module, and (iii) signal-quality aware ECG analysis and transmission module. Fig.- 3 Signal Quality- The main focus on design and real implementation of automated ECG signal quality assessment method and validation of the effectiveness of the proposed SQA-IoT framework under resting, ambulatory and physical activity conditions, proposed automated ECG signal quality assessment (ECG-SQA) method consists flat-line (or ECG signal absence) detection, abrupt baseline wander extraction, and high detection and extraction to compute the signal quality index (SQI) for assessing the clinical acceptability of ECG signals. In this work, the ECG implemented based on the-based filtering, turning points and decision rules. I] HF Noise Detection – The high frequency (HF) noises such as muscle artifacts, power line interference, motion artifacts, pause and instrument noise ar acquired ECG signal. Apply decision rules for detecting the ECG segment with HF noises where R1 is true if a total number of turning points in any block (tpk) exceeds 5% of the number of samples International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 218 serves the function to transfer the data in between PC and the FPGA, for the further operation of the system Computer / PC is used in a project to visualize the output of the application. Computer / PC is interfaced for the Electrocardiography. A waveform of ECG can be visualize on Computer /PC. PROPOSED METHODOLOGY The main modules of signal quality-aware (SQA)-IoT framework are illustrated in Fig. It consists of three ules: (i) ECG signal sensing module, (ii) automated signal quality assessment module, and (iii) quality aware ECG analysis and transmission -aware framework The main focus on design and real-time automated ECG signal quality assessment method and validation of the effectiveness IoT framework under resting, nd physical activity conditions, The proposed automated ECG signal quality assessment SQA) method consists of three steps such as line (or ECG signal absence) detection, abrupt baseline wander extraction, and high-frequency noise detection and extraction to compute the signal quality index (SQI) for assessing the clinical acceptability of his work, the ECG-SQA is based filtering, turning The high frequency (HF) noises such as muscle artifacts, power line interference, motion artifacts, pause and instrument noise are introduced in the acquired ECG signal. Apply decision rules for detecting the ECG segment with HF noises- where R1 is true if a total number of turning points in ) exceeds 5% of the number of samples
  • 4. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com (P ∗ F s, where, F s is the sampling frequency of the signal) in that block and R2 is true if the distance between two turning points rk is less than two. If SQIHF = 1 then the segment is classified as a HF noise segment. Otherwise the segment is classified as a high frequency noise-free ECG segment. II] ECG signal absence detection- Due to the disconnection of electrodes with skin and the electronic component saturation, sensing device exhibits the absence of ECG signal information in the acquired signal. In practice, observation to the recording shows the presence of zero amplitude flat line (ZFL), only baseline wander (OBW), and the long pause with physiological and external noises. Existing approaches were developed for detection of ZFL event. It is based on turning poin can be computed as mentioned in Algorithm. If SQIFL = 1 then the segment is classified as a flat line or ECG signal absence segment. Otherwise the segment is further processed for detecting the presence of high frequency noises. III] Abrupt Change Detection- The ECG signals are corrupted by baseline wanders that are mainly caused by respiratory activity, body movements, skin-electrode interface, varying impedance between electrodes and skin due to poor electrode contact. By using FIR Based –The basic structure of FIR filter is like a sub-section of the delay lines. Each section of the output of the weighted cumulative, the FIR coefficient is- y(nT). = . ℎ(𝑘) 𝑥(𝑛 − 𝑘 The baseline wander signal is obtained as b[n] = x[n] - x~ [n] Where b (n) is the baseline wander signal and is the baseline wander removed signal which is computed as International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 is the sampling frequency of the signal) in that block and R2 is true if the distance is less than two. If SQIHF = 1 then the segment is classified as a HF noise segment. Otherwise the segment is classified as free ECG segment. Due to the disconnection of electrodes with skin and the electronic component saturation, sensing device exhibits the absence of ECG signal information in the rvation to the recording shows the presence of zero amplitude flat line (ZFL), only baseline wander (OBW), and the long pause with physiological and external noises. Existing approaches were developed for detection of ZFL event. It is based on turning points (TP) which can be computed as mentioned in Algorithm. If SQIFL = 1 then the segment is classified as a flat line or ECG signal absence segment. Otherwise the segment is further processed for detecting the The ECG signals are corrupted by baseline wanders that are mainly caused by respiratory activity, body electrode interface, varying impedance between electrodes and skin due to poor The basic structure of FIR filter section of the delay lines. Each section of the output of the weighted cumulative, the FIR 𝑘) The baseline wander signal is obtained as- ) is the baseline wander signal and x~ (n) is the baseline wander removed signal which is The detection decision rule is given by Where SQIABW denotes the signal quality index (SQI) for the presence of abrupt baseline drift (ABW) event. Here, the γ is chosen as 0 abrupt baseline wander which can distort the ST segment and other low-frequency components of the ECG signal. The ECG signal with abrupt baseline wander event is classified as an ECG signal with slowly varying baseline wander is classified as an acceptable since it can be removed from the signal without significantly distorting the PQRST complexes. IV] ECG Signal Quality Grading The grading of acquired ECG signal based on the decision scores obtained for the detection of abrupt baseline wander, ECG signal absence, and high frequency noises. The ECG signal is graded with three classes such as Good, Intermediate and bad based on the HF noise score. The presence of flat line and abrupt baseline wander may result in noisy clinical features. Based upon assessment results, it is noted that the some morphological features and RR intervals can be measured from the ECG signal with some level of HF noises. Thus, we grade the noisy ECG signal into intermediate γH is chosen as 0.1% of the maxima or minima in the HF noise detection stage for detecting severe noise or bad quality signal. While the noise level threshold is set to 0.05% of the maxima or minima for grading the noisy signal into intermediate Where overall signal quality index (SQI) is computed as SQI = SQIABW + SQIFL + SQIHF Good quality indicates the ECG signal with acceptable level of noise which does not distort the morphological features while indicate the medium and high level of noise or poor quality, respectively. The intermediate class of ECG signals may be considered for application ECG signal analysis systems. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 219 The detection decision rule is given by- SQIABW denotes the signal quality index (SQI) for the presence of abrupt baseline drift (ABW) is chosen as 0:2 mV for detecting abrupt baseline wander which can distort the ST frequency components of the . The ECG signal with abrupt baseline wander event is classified as an unacceptable. The ECG signal with slowly varying baseline wander is since it can be removed from the signal without significantly distorting the IV] ECG Signal Quality Grading- The grading of acquired ECG signal based on the decision scores obtained for the detection of abrupt baseline wander, ECG signal absence, and high frequency noises. The ECG signal is graded with ood, Intermediate and bad based on the HF noise score. The presence of flat line and abrupt baseline wander may result in noisy clinical features. Based upon assessment results, it is noted that the some morphological features and RR red from the ECG signal with some level of HF noises. Thus, we grade the noisy intermediate and bad. The value of is chosen as 0.1% of the maxima or minima in the HF noise detection stage for detecting severe noise or While the noise level threshold γH is set to 0.05% of the maxima or minima for grading intermediate class. overall signal quality index (SQI) is computed SQI = SQIABW + SQIFL + SQIHF Good quality indicates the ECG signal with acceptable level of noise which does not distort the morphological features while intermediate and bad indicate the medium and high level of noise or poor quality, respectively. The intermediate class of ECG ls may be considered for application-specific
  • 5. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com B] For Androd Application-  ALGORITHM- 1. Initialize central processing unit 2. Initialize Ports 3. Initialize memory 4. Initialize ADC 5. Connect 3-leads of electrode in correct place 6. Read the signals from the sensor and transmit signals to the amplifier 7. Convert analog signal to digital signal u ADC3204 8. Display the ECG signal on PC 9. Also display on Android phone V. SYSTEM IMPIMENTATON A] Software Implementation 1.1 Mit-Bih Database The dataset used in this study is obtained from Physiobank entitled MIT-BIH Arrhythmia Database available on-line. MIT-BIH Arrhythmia Database which having sources of ECGs includes set of over 4000 long-term Holter recorders, which was obtain from Beth Israel Hospital Arrhythmia Laboratory. Each signal is recorded with 360 sampling frequency which having 11-bit resolution with 10 mv range. MIT-BIH Arrhythmia Database where annotated ECG signals are described by a text header file (.hea), a binary file (.dat) and a binary annotated file (.atr). Header file consists of detailed information such as number of samples, sampling frequency, format of ECG signal, type and number of ECG leads, patient’s history and the detailed clinical information. In binar data signal file, the signal is stored in 212 format which means each sample requires number of lead times 12 bits to be stored and the binary annotation file consists of beat annotation from which database has been freely available .For EMG is obtained from MIT-BIH Noise stress database from PhysioBank. Noise stress database includes 12 half hour ECG recordings and 3 half-hour recordings. This is having a noise typical in ambulatory ECG recordings. PhysioBank noise recordings were taken by physical activities of volunteers. For ECG recording 3 noise records were assembled. These recordings were contain predominantly baseline wander (as 'bw'), muscle artifact (as 'ma') which also known as EMG noise and third one is electrode motion artifact (as 'em'). From noise stress database records of ‘bw’ contains primarily baseline wander with low frequency signals, which was caused by motion of the volunteer or the leads. Recorded ECG ‘em’ contains electrode motion artifacts with International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 electrode in correct place Read the signals from the sensor and transmit tal signal using The dataset used in this study is obtained from BIH Arrhythmia Database BIH Arrhythmia Database which having sources of ECGs includes set of over term Holter recorders, which was obtain Beth Israel Hospital Arrhythmia Laboratory. Each signal is recorded with 360 sampling frequency bit resolution with 10 mv range. BIH Arrhythmia Database where annotated ECG signals are described by a text header file (.hea), a ile (.dat) and a binary annotated file (.atr). Header file consists of detailed information such as number of samples, sampling frequency, format of ECG signal, type and number of ECG leads, patient’s history and the detailed clinical information. In binary data signal file, the signal is stored in 212 format which means each sample requires number of lead times 12 bits to be stored and the binary annotation file consists of beat annotation from which half of this For EMG dataset BIH Noise stress database from Noise stress database includes 12 half- hour recordings. This is having a noise typical in ambulatory ECG recordings. PhysioBank noise recordings were taken by physical activities of volunteers. For ECG ds were assembled. These recordings were contain predominantly baseline wander (as 'bw'), muscle artifact (as 'ma') which also known as EMG noise and third one is electrode motion artifact (as 'em'). From noise stress database arily baseline wander with low frequency signals, which was caused by motion of the volunteer or the leads. Recorded ECG ‘em’ contains electrode motion artifacts with significant amounts of muscle noise and baseline wander. Recorded ECG ‘ma’ contains prima muscle noise (EMG) with spectrum, which overlaps that of the ECG, which extends to higher frequency. 1.2 MATLAB MATLAB is a powerful, comprehensive, and easy to use environment for technical computations, greatest strengths is that MATLAB own reusable tools. Mat lab database extraction which is stored at www.physiobank.org. Stored ECG signal can be called in Simulink model from workspace of Real time EMG noise is accessed from MIT noise stress database in the form of .mat file then it is imported into workspace which is added with pure ECG in Simulink model. For designing of FIR low pass filter FDA Tool from MATLAB Different types of FIR digital filter designed to remove high frequency EMG noise. 1.3 FIR FILTER FIR filters are widely used because of inherent stability and due to the powerful design algorithms which are exist from them. When FIR filters implement in non-recursive f can obtain with ease. FIR low pass filter is designed by equiripple filtering, least square method, windowing method for designing have been used. In windowing method such as Kaiser, Rectangular, Hamming, Hanning and Blackman function designed. 1.4 Flow chart for MATLAB programming 1.5 Simulink model for F International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 220 significant amounts of muscle noise and baseline wander. Recorded ECG ‘ma’ contains primarily muscle noise (EMG) with spectrum, which overlaps that of the ECG, which extends to higher frequency. is a powerful, comprehensive, and easy to ment for technical computations, one of its greatest strengths is that MATLAB allows building its is being used for ECG database extraction which is stored at . Stored ECG signal can be called in Simulink model from workspace of mat lab. EMG noise is accessed from MIT-BIH noise stress database in the form of .mat file then it is imported into workspace which is added with pure ECG in Simulink model. For designing of FIR low Tool from MATLAB has been used. of FIR digital filter designed to remove high frequency EMG noise. FIR filters are widely used because of inherent stability and due to the powerful design algorithms which are exist from them. When FIR filters recursive form, linear phase one can obtain with ease. FIR low pass filter is designed by equiripple filtering, least square method, windowing method for designing have been used. In windowing method such as Kaiser, Rectangular, Hamming, Hanning and Blackman functions are ow chart for MATLAB programming 1.5 Simulink model for FIR filter
  • 6. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com Fig4- Simulink Model of ECG De In above fig-4 it show that the design of The filters are designed using MATLAB FDA Tool by specifying the filter order, cut off frequency and sampling frequency. In the present section, the design considerations of low pass filter, high pass filter, notch filter are elaborated separately for noise signals from ECG using FIR filter. For ECG de noising the digital filter is designed with various orders. Output of this various designs are simulated and analyzed with the help of performance parameters like SNR and MSE. B] HARDWARE IMPLEMENTATION The implementation of the design is fundamental to move from software to a hardware realization. The implementation technique exploits the parallel structure and the versatility of Field Programmable Gate Arrays (FPGAs) in order to yield a high performance and yet low cost implementation. The step by step procedures that are used to complete this project are highlighted. They are explained in below. The explanations are important in complete the objectives of the project. As shown in below flow chart, the implementation procedure will be followed. The board at transmitter side will be FPGA board and at the receiver side the board will be Bluetooth model and Arduino in this digital hardware system. Fig5-Experimental setup of telemetry system International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 imulink Model of ECG De-noising 4 it show that the design of FIR filter. designed using MATLAB FDA Tool order, cut off frequency and sampling frequency. In the present section, the design high pass filter, notch filter are elaborated separately for removal of R filter. For ECG de- g the digital filter is designed with various orders. Output of this various designs are simulated and analyzed with the help of performance parameters IMPLEMENTATION The implementation of the design is fundamental to move from software to a hardware realization. The implementation technique exploits the parallel structure and the versatility of Field Programmable Gate Arrays (FPGAs) in order to yield a high performance and yet low cost implementation. step procedures that are used to complete this project are highlighted. They are explained in below. The explanations are important in complete the objectives of the project. As shown in below flow chart, the implementation procedure will be followed. board at transmitter side will be FPGA board and at the receiver side the board will be Bluetooth model and Arduino in this digital hardware system. try system FLOW CHART The experimental setup of the system which includes FPGA board, ECG sensor, Arduino ECG waveform display on mon applicatonis given in below figure: Fig 6-Experimental setup of system VI. RESULT AND DISCUSSION I] Matlab Simulation Result Clean ECG is taken from MIT with low frequency noise. Simulation was done on SIMULINK available with MATLAB. Fig.7shows pure ECG from MIT-BIH Arrhythmia database of patient shows noisy ECG. Fig. of different FIR filter methods on low frequency EMG noise. Equation (1) is used to calculate SNR of filtered signal and mean square error (MSE) from equation (2) is calculated. N ∑ (ECG raw) 2 SNR= 10 log10 N∑ (ECG raw – ECG filtered) 2 i= N∑ (ECG raw – ECG filtered)2 MSE = N International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 221 FLOW CHART The experimental setup of the system which includes Arduino& Bluetooth, the display on monitor and Android is given in below figure: Experimental setup of system DISCUSSION Clean ECG is taken from MIT-BIH which is added Simulation was done on SIMULINK available with MATLAB. Fig.7shows BIH Arrhythmia database of patient shows noisy ECG. Fig.8shows the application of different FIR filter methods on low frequency EMG noise. Equation (1) is used to calculate SNR of filtered signal and mean square error (MSE) from SNR= 10 log10 i=0 ----- (1) MSE = i=0 N -----(2)
  • 7. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com Fig 7- Noisy ECG Signal Fig 8-Filtered ECG Signal Types and order of the FIR Filter ECG Sample SNR in dB Mean Error Blackman low pass filter (100) Ecg24 19.21 Hamming low pass filter (100) Ecg24 19.20 Hanning low pass filter (100) Ecg24 19.21 Kaiser low pass filter (100) Ecg24 18.67 Rectangular low pass filter (100) Ecg24 19.11 Table 1 - Performances and evaluation of FIR low pass filters on MIT-BIH database. The value shows SNR in dB. In Table 1 comparison of different FIR method for SNR and MSE is given. Here it can be concluded that FIR method effectively remove the EMG nois without distortion of the ECG signal. In case of Equiripple, Hamming, Hanning order of the filter was increased which increases the complexity of filter designing. So that SNR of FIR filter with Kaiser is (18.67) less than other type of filter. In case o method the order of the filter easily grow very much .It increases the number of filter coefficient which leads to the large memory requirement and problems in hardware implementation. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 Filtered ECG Signal Mean Square Error (MSE) 25.67 25.67 25.67 25.42 25.62 Performances and evaluation of FIR low BIH database. The value shows SNR in dB. In Table 1 comparison of different FIR method for SNR and MSE is given. Here it can be concluded that FIR method effectively remove the EMG noise without distortion of the ECG signal. In case of Equiripple, Hamming, Hanning order of the filter was increased which increases the complexity of filter designing. So that SNR of FIR filter with Kaiser is (18.67) less than other type of filter. In case of other method the order of the filter easily grow very much .It increases the number of filter coefficient which leads to the large memory requirement and problems B] Hardware Implementation Result I] Waveform Analysis- The output waveforms generated by FIR filter give better filtered output. The output waveforms are generated with normal ECG signal signal, filtered low pass signal and peak detection as shown in fig.9 below Fig.9- De-noising ECG Signal Spartan Hardware kit. When the real time ECG signal display on the PC then at time it display on the android application. The ECG output waveforms display on the Android phone as shown in fig. 10 – Fig. 10- ECG waveform display o applicaton. II] DEVICE UTILIZATION SUMMARY AND POWER ANALYSIS a) Device Utilization- After implementation on Spartan FPGA kit, utilization of resources i.e. no of LUTs, Slices, Bonded I/O has been calculated for different types of FIR filter. Fig. 11- shows that Equiripple requires highest no. of slices, flip-flop,4 input LUTs, bonded IOB with 1GCLK. In window method Kaiser has minimum utilization of resources. As it require 87 slices, 156 slices, Flip flop, 111 LUTs, 17 bonded IOB, with 1 GCLK. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 222 Hardware Implementation Results output waveforms generated by FIR filter give better filtered output. The output waveforms are generated with normal ECG signal, filtered high pass filtered low pass signal and peak detection as noising ECG Signal by FIR Filter by using Hardware kit. When the real time ECG signal display on the PC then at time it display on the android application. The ECG output waveforms display on the Android phone as ECG waveform display on Android applicaton. DEVICE UTILIZATION SUMMARY AND POWER ANALYSIS- After implementation on Spartan FPGA kit, utilization of resources i.e. no of LUTs, Slices, Bonded I/O has been calculated for different types of shows that Equiripple requires flop,4 input LUTs, bonded IOB with 1GCLK. In window method Kaiser has minimum utilization of resources. As it require 87 Flip flop, 111 LUTs, 17 bonded
  • 8. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com Fig.11- Device Utilization Report of FIR Filter b) Power analysis- Power analysis will generate the timing, ISE report and power utilization report for the particular design. Snapshots of Power Analyzer for FIR filter shown in Fig. 12- Fig.12- Device Utilization Report of FIR Filter VII. CONCLUSON In this research paper, the implementation of FIR filter on FPGA has been introduced. It has been investigated that, the improvement of noisy ECG signals can be achieved by combination of FIR In order to measure the performance of de SNR of processed ECG is calculated and MSE was determined to find the degree of mismatch between noisy ECG and filtered. The designed FIR filter with Kaiser Window works excellent in removing High frequency interference from noisy ECG conditions utilizing low order of filter. Utilization of resources using FIR filter has been minimizedi. consumption (74mw)and minted the quality of ECG signal. This method is more applicable in variou applications of ECG monitoring. Use of optimization technique using FPGA platform will improve the quality and processing time. FPGA are finding wide acceptance in medical system. For their ability for rapid prototyping of a concept that requires hardware/software co-design, for performing custom processing in parallel at high data rates. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 Device Utilization Report of FIR Filter Power analysis will generate the timing, ISE report and power utilization report for the particular design. Snapshots of Power Analyzer for FIR filter shown in tilization Report of FIR Filter In this research paper, the implementation of FIR filter on FPGA has been introduced. It has been investigated that, the improvement of noisy ECG signals can be achieved by combination of FIR filters. In order to measure the performance of de-noising, SNR of processed ECG is calculated and MSE was determined to find the degree of mismatch between noisy ECG and filtered. The designed FIR filter with Kaiser Window works excellent in removing High frequency interference from noisy ECG conditions utilizing low order of filter. Utilization of resources e. less power and minted the quality of ECG This method is more applicable in various Use of optimization technique using FPGA platform will improve the quality and processing time. FPGA are finding wide acceptance in medical system. For their ability for rapid prototyping of a concept that requires design, for performing custom processing in parallel at high data rates. VIII. FUTURE SCOPE The implementation of FIR High Pass filter techniques gives better results on higher end FPGA devices like Virtex, which are having more and facilities than Spartan devices. be successfully applied with the cascading of IIR and FIR filters for real time ECG systems. Finally, it is seen that an optimum combination can be implemented using FPGA technique. IX.REFERANCES 1. Yongming Yang I, Xiaobo Huang 1, Xinghuo Yu, “Real-Time ECG Monitoring System Based on FPGA ”, The 33rd Annual Conference of the IEEE Industrial Electronics Society (IECON) Nov. 5-8, 2007. 2. Borromeo S, Rodriguez-Sanchez C, Machado F, Hernandez-Tamames JA, de la Prieta R. Reconfigurable, Wearable, Wireless ECG System ”, the 29th Annual International Conference of the IEEE EMBS Cité Internationale, Lyon, France August 23-26, 2007. 3. Brian A. Walker#, Ahsan H. Khandoker#, and Jim Black, “Low Cost ECG Monit Countries” , 2009 4. ndrej Krejcar, Dalibor Janckulik, Leona Motalova, Karel Musi, “Real Time Processing of ECG Signal on Mobile Embedded Monitoring Stations ”, Second International Conference on Computer Engineering and Applications, 2010. 5. Ankit J. Gordhandas and George C. Verghese, “Real Analysis of Key Morphological Features in the Electrocardiogram, for Data Compression and Clinical Decision Support”, 6. Abhilasha M. Patel, Pankaj K. Gakare, A. Cheeran, “Real Time ECG Feature Extraction and Arrhythmia Detection on a Mobile Platform International Journal of Computer Applications (0975 – 8887) Volume 44– 7. Sonal K. Jagtap, Research Student Approach: ECG Noise Red Type II Digital Filter”, International Journal of Computer Applications (0975 49– No.9, July 2012. 8. Sayanti Chattopadhyay1, Susmita Das2, Avishek Nag3, Jayanta Kumar Ray4, Soumyendu Bhattacharjee5, Dr. Biswarup Neogi, “Des Simulation Approach Introduced to ECG Peak International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 223 The implementation of FIR High Pass filter techniques gives better results on higher end FPGA devices like Virtex, which are having more resources and facilities than Spartan devices. This method can be successfully applied with the cascading of IIR and FIR filters for real time ECG systems. Finally, it is seen that an optimum combination can be implemented using FPGA technique. Yongming Yang I, Xiaobo Huang 1, Xinghuo Yu, Time ECG Monitoring System Based on FPGA ”, The 33rd Annual Conference of the IEEE Industrial Electronics Society (IECON) Sanchez C, Machado F, A, de la Prieta R. “A Reconfigurable, Wearable, Wireless ECG System the 29th Annual International Conference of the IEEE EMBS Cité Internationale, Lyon, France Brian A. Walker#, Ahsan H. Khandoker#, and Jim Black, “Low Cost ECG Monitor for Developing ndrej Krejcar, Dalibor Janckulik, Leona Motalova, Real Time Processing of ECG Signal on Mobile Embedded Monitoring Stations ”, Second International Conference on Computer Engineering and Applications, 2010. and Thomas Heldt and Real-Time Extraction and Analysis of Key Morphological Features in the Electrocardiogram, for Data Compression and Clinical Decision Support”, AAAI 2011. Abhilasha M. Patel, Pankaj K. Gakare, A. N. Real Time ECG Feature Extraction and Arrhythmia Detection on a Mobile Platform”, International Journal of Computer Applications – No.23, April 2012 Sonal K. Jagtap, Research Student, “A Real Time Approach: ECG Noise Reduction in Chebyshev International Journal of Computer Applications (0975 – 8887) Volume Sayanti Chattopadhyay1, Susmita Das2, Avishek Nag3, Jayanta Kumar Ray4, Soumyendu Bhattacharjee5, Dr. Biswarup Neogi, “Design and Simulation Approach Introduced to ECG Peak
  • 9. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 @ IJTSRD | Available Online @ www.ijtsrd.com Detection with Study on Different Cardiovascular Diseases”, December 2012. 9. Masudul Haider Imtiaz & Md. Adnan Kiber, “Design and Implementation of a Real Automated ECG Diagnosis (AED) System”, 2013 10. Bhushan N. Patil, “A Review of ECG Monitoring System Using Wavelet Transform” Journal of Research in Advent Technology, Vol.2, No.4, April 2014. 11. Prerana N Gawale1, A N Cheeran2, Nidhi G Sharma, “Android Application for Ambulant ECG Monitoring”, International Journal of Advanced Research in Computer and Communication Engineering Vol. 3, Issue 5, May 2014. 12. Luca Catarinucci, Danilo De Donno, Luca Mainetti, Luca Palano, Luigi Patrono, Maria Laura International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456 www.ijtsrd.com | Volume – 3 | Issue – 1 | Nov-Dec 2018 Detection with Study on Different Cardiovascular Masudul Haider Imtiaz & Md. Adnan Kiber, “Design and Implementation of a Real-Time Automated ECG A Review of ECG Monitoring System Using Wavelet Transform” International Journal of Research in Advent Technology, Vol.2, Prerana N Gawale1, A N Cheeran2, Nidhi G Android Application for Ambulant ECG International Journal of Advanced Research in Computer and Communication Luca Catarinucci, Danilo De Donno, Luca Mainetti, Luca Palano, Luigi Patrono, Maria Stefanizzi, and Luciano Tarricone, “An IoT Aware Architecture for Smart Healthcare Systems ”, IEEE Internet of Things Journal, DOI 10.1109/JIOT.2015. 13. Sudip Deb, Sheikh Md. Rabiul Islam, Jannatul RobaiatMou, Md. Tariqul Islam,” Design and Implementation of Low Cost ECG Monitoring System for the Patient u February 16-18, 2017Feb 2017. 14. Udit Satija, Student Member, Ramkumar, and M. Sabarimalai Manikandan, Member, IEEE “Real-Time Signal Quality ECG Telemetry System for IoT Care Monitoring” IEEE Internet Journal, DOI 10.1109/JIOT.2017. 15. R.Harini1, B. Rama Murthy2 , K. “DEVELOPMENT OF ECG MONITORING SYSTEM USING ANDROID APP ”, March 2017. International Journal of Trend in Scientific Research and Development (IJTSRD) ISSN: 2456-6470 Dec 2018 Page: 224 Stefanizzi, and Luciano Tarricone, “An IoT- Architecture for Smart Healthcare Systems ”, IEEE Internet of Things Journal, DOI Sudip Deb, Sheikh Md. Rabiul Islam, Jannatul Md. Tariqul Islam,” Design and Implementation of Low Cost ECG Monitoring System for the Patient using Smart Device”, , 18, 2017Feb 2017. Udit Satija, Student Member, IEEE, Barathram. Ramkumar, and M. Sabarimalai Manikandan, Time Signal Quality-Aware ECG Telemetry System for IoT-Based Health Care Monitoring” IEEE Internet of Things DOI 10.1109/JIOT.2017. R.Harini1, B. Rama Murthy2 , K. Tanveer Alam, OPMENT OF ECG MONITORING USING ANDROID APP ”, March