The article a study on physical activity and health literacy in adult population with reference to Kanyakumari district. The present article shows the profile and awareness about physical activity and health literacy in Adults in the Study area. The health conditions prevailing in India is different. Usually the people care their children health only during childhood and after that when they become adults, they totally neglect about health aspects of their children. When children reach adolescence, they have to choose their career as professionals or non-professionals. Due to various environmental impacts and in the process of life circumstances, they forget about the concept and development of fitness or health-related activities. The major difference between physical activity and health-related physical fitness components are body composition, immunity, briskness, strength and ability. The present study is descriptive in nature using both primary data and secondary data. Primary data were collected through interview schedule from the respondents in the study area. Secondary data were collected from various journals, magazines, newspaper related website and records of etc. the collected primary data were analyzed by using appropriate Statistical tools like Simple percentage, ANOVA, Chi-square test. The study is based on simple random sampling technique. The researcher has collected the primary data through survey fact investigation impact of physical activity and health literacy in adult population with reference to Kanyakumari District. 10villages were selected in Kanyakumari district, 11 respondents from each village were selected on the basis of convenience sampling techniques. Hence, the total sample size is restricted to 110 respondents for the study.