Sulfide mineralization are the main resource for exploiting Pb, Zn, and Cu metals in Egypt. Sulfide mineralization is represented by four sulfide types of the different setting, lithology and ages, namely: i) Lead-Zinc sulphide Deposits ii) Cu-NiCo sulphide Deposits This type of mineralization is well represented in Abu Swayel in South Eastern Desert. The ore is closely related to mafic-ultramafic and gabbro of ophiolitic rocks. iii) Cu-Ni sulphide deposits This type of mineralization occurs in layered mafic-ultramafic intrusions like gabbro rocks at Akarm and El Geneina . iv) Stratiform Massive Sulphide (Zn-Cu-Pb) Deposits This type of mineralization is represented by a group of small lenses associated with talc deposits in South Eastern Desert at: Um Samuki, Helgit, Maakal, Atshan, Darhib, Abu Gurdi, and Egat.