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The Adrenal, Immune,
Inflammatory Trilogy
HRV Interpretation
by Glen Depke, Traditional Naturopath
An Empowering Partnership
• HRV Interpretation
• Chiropractic Care
• Functional Recovery Program
• Business Models
The Healing Trilogy
• Brain/Hypothalamus
• Pituitary
• Adrenal
• Thymus
• Thyroid
• Pancreas
• Ovary
• Testicle
• Pineal
• Spinal column
www.DepkeWellness.com
Neuroendocrine System
• Reviewed over 4,600 adrenal saliva test kits
• These statistics are based on individuals with some
type of health challenge
• I have seen only 5 people test in the normal range
• Approximately 1/10th of 1 percent were actually in a
normal range
• If you are not testing adrenal function, you are leaving
people in the dark
Percentage of Health Challenged
Individuals with Adrenal Insufficiency
Adrenal Stress Response
www.DepkeWellness.com
Affects of Stress (High Cortisol)
 Accelerates aging
 Hypertension
 Immune dysfunction
 Subluxation
 Fatigue
 Protein deficiency
 Insulin resistance
 Weight gain
 Muscle breakdown
 Osteoporosis
 Inhibits human growth
hormone
 Neuron death
 Depression
 Hippocampus dysfunction
 Poor memory
 Insomnia
 PMS
 Hypothalamus dysfunction
 Menopause symptoms
 Infertility
 Impairs healing of wounds
 Destroys tryptophan
 Inhibits testosterone
 Decreased glutamine
www.DepkeWellness.com
Adrenal Stress Response
www.DepkeWellness.com
Cortisol
Pregnenolone
B5Acetyl CoA
Cholesterol
Androstenedione
19 - Hydroxy -
androstenedione
Estrone
Estradiol - 17β
17α - Hydroxylation
Testosterone
5α - Dihydro -
testosterone
19 - Hydroxy -
testosterone
Estradiol - 17α
Progesterone
17 - Hydroxyprogesterone
11 - Deoxycortisol
Cortisone
Adrenal Stress Response
Androstenediol
17- Hydropregnenolone
Dehydro -
epiandrosterone
www.DepkeWellness.com
Triggers for Adrenal Insufficiency
• Mental/emotional
• Subluxation
• Nutritional
– SAD
– Food Intolerance
• Chemical
– Toxins
– Emotional response
• Inflammation
• Infection
Stress Response Gone Too Far
• Diabetes Mellitus
• Cardiovascular Disease, High
Blood Pressure, Elevated
Blood Fats
• Infertility, PMS, Menopause
Symptoms
• Autoimmune disease
• Chronic inflammation
• Osteoporosis
• CFS/Fibromyalgia
• Cancer
• Chronic Illness
www.DepkeWellness.com
Assess Your Likelihood of
Adrenal Fatigue
• Take your complimentary
adrenal stress profile
assessment
• What’s your score?
• How I use this in my
practice.
www.DepkeWellness.com
Reduce or Eliminate Your Triggers
• Laugh and play
• Chiropractic adjustments
• Learn empowering
emotional release
• Eat well and eliminate food
sensitivity
• Reduce your toxic load
• Create and anti-
inflammatory effect
• Assess and eliminate
infection
www.DepkeWellness.com
Proper Supplement Support
• Vitamin B5
(Pantothenic Acid)
• Zinc
• Vitamin C
• B-Complex
• Ashwagandha
• Magnesium
• Pregnenolone
• DHEA
www.DepkeWellness.com
Nutritional Support
• Digestive Function
• Chiropractic
• Food Sensitivity
• Nutritional ID
www.DepkeWellness.com
Assisting Adrenal Function
• Look for signs
• Heart Rate Variability
• Use your complimentary assessment
• Testing adrenal function (saliva)
• Reduce or eliminate triggers
• Balancing Adrenals
• Enjoy improved health and happiness
www.DepkeWellness.com
• Deeper understanding of every patient
• Improved results with spinal adjustments
• Accelerated improvement in patient health
• Increased revenue for your practice
– 10 Adrenal test kits weekly
– 10 follow up consultations
– Basic supplementation for each patient
– Continued follow up appointments, testing and supplements
It’s a Win/Win for Your
Practice
• Minimum yearly revenue increase
based on 10 adrenal test kits weekly
– Adrenal test kit revenue $237,120.00
– Follow up consultation $166,400.00
– Basic supplement recommendations
$320,320.00
– Minus cost of testing -$205,920.00
– Minus cost of supplements -$160,160.00
– Staffing cost -$83,200.00
– Minimum Net income $274,560.00
It’s a Win/Win for Your
Practice
HRV Interpretation
• HRV is a constant evaluation
necessary to track the
combined approach of
adaptive responses.
• Chiropractic is the essential
foundation behind the
adjunctive wellness
strategies. Indeed
adjustments alone are not
the final answer.
• Chiropractic “sets the table
for health and wellness”
www.DepkeWellness.com
The Dead End of Many
Functional Medicine Practices
• Introduce the symptoms of chronic inflammation
• Describe the importance and influence of NF-kB state
• Identify potential inflammatory triggers
• Identify and explain chronic inflammatory feedback
loops
• Expose the functional medicine dead end
• Assist in understanding chronic inflammation out of
control
• Discuss moving forward to support the body in
overcoming chronic inflammation
www.DepkeWellness.com
The PAIN of Inflammation
• Does it take you a bit to get moving in the morning
• Do you feel aches and pains with regularity
• Are you stiff getting up from your desk
• Are you challenged with chronic disease
• Do you feel that your belly is bloated
• Has weight gain been an issue for you
• Are you feeling fatigued and frustrated
www.DepkeWellness.com
Early Signs of Chronic Inflammation?
Did you know that most with chronic inflammation is
not diagnosed until this is already a significant health
issue?
www.DepkeWellness.com
The PAIN of Inflammation
The PAIN of Inflammation
• Did you know that approximately
116 million Americans suffer with
chronic pain, which is about 1/3
of our country?
• Recognize that chronic pain is
almost always tied into chronic
inflammation.
• What is your PAIN?
www.DepkeWellness.com
• acid reflux/heartburn
• acne
• allergies/sensitivities
• Alzheimer’s disease
• asthma
• atherosclerosis
• bronchitis
• cancer
• celiac disease
• chronic pain
• autoimmunity
• Crohn’s disease
• cirrhosis
• colitis
• dementia
• dermatitis
• diabetes
• dry eyes
• edema
• emphysema
www.DepkeWellness.com
Symptoms Associated with
Chronic Inflammation
• eczema
• fibromyalgia
• gastroenteritis
• gingivitis
• heart disease
• hepatitis
• high blood pressure
• insulin resistance
• interstitial cystitis
• obesity
• joint pain/ arthritis/
rheumatoid arthritis
• metabolic syndrome
(syndrome X)
• myositis
• nephritis
• osteopenia
• osteoporosis
• Parkinson’s disease
• periodontal disease
www.DepkeWellness.com
Symptoms Associated with
Chronic Inflammation
• polychondritis
• psoriasis
• scleroderma
• sinusitis
• Sjögren’s syndrome
• spastic colon
• systemic candidiasis
• tendonitis
• UTI’s
• vaginitis
www.DepkeWellness.com
Symptoms Association with
Chronic Inflammation
Healthy Immune/Inflammatory Reaction
www.DepkeWellness.com
Stress Food Infection
Immune
Reaction
Inflammation
Adrenal
Function
• Nutritional
– SAD
– Food sensitivity
• GI challenges
– Infections
• Stress
• Subluxation
• Obesity
• Chemotherapy
• Toxicity
www.DepkeWellness.com
Main Inflammatory Triggers
www.DepkeWellness.com
The Functional Medicine Dead End
Stress Food Infection
Adrenal
Function
Inflammation
Omega 3’s
www.DepkeWellness.com
NF-kB Out of Control
NF-kB
Increased
Fat Cells
Leaky Gut
Cytokine
Release
Hepatic
Disruption
• Nuclear Factor Kappa Beta
– A protein complex that controls the transcription of
DNA
– It is found in all cell types and is involved in cellular
responses to stimuli such as stress, cytokines, free
radicals and antigens
– Controls the expression of genes encoding the pro-
inflammatory cytokines, chemokines, adhesion
molecules, inducible enzymes (COX-2 and iNOS) and
growth factors
– Chronically elevated NF-kB is linked to cancer,
inflammatory conditions and autoimmunity
www.DepkeWellness.com
What is NF-kB?
• Increase in fat cell production
• Insulin resistance
• Insulin surges
• More inflammation
www.DepkeWellness.com
NF-kB Feedback Loops
• Tight junction breakdown
• Leaky gut
• Immune activation
• More inflammation
www.DepkeWellness.com
NF-kB Feedback Loops
• Suppression of cytochrome
P450
• Hepatic (liver)
biotransformation
• Activated liver end products
• Add environmental triggers
and…
• More inflammation
www.DepkeWellness.com
NF-kB Feedback Loops
• Immune cell activation
• Cytokine release
• Self-amplifying loop
• Autoimmunity
• More inflammation
www.DepkeWellness.com
NF-kB Feedback Loops
www.DepkeWellness.com
Chronic NF-kB Response
Immune
Dysregulation
Multiple
Chemical
Sensitivities
Cancer
Auto-
Immunity
Apoptosis
• Inflammatory triggers
• Chronic Inflammation/
NF-kB
• Neurotransmitter
Bradykinin
• PAIN
www.DepkeWellness.com
The PAIN of Inflammation
• Nutrition
– Food Sensitivity
• Blood Testing
• Food elimination diets
– Standard American Diet (SAD)
• Significantly reduce or sugar and processed foods
• Reduce or eliminate alcohol consumption
• Eliminate gluten and/or other food sensitivities
• Eat according to your Nutritional ID
www.DepkeWellness.com
Moving Forward w/Support
• Chronic stress
– Chiropractic Adjustments
– Deep breathing
– Meditation
– Prayer
– Yoga
– Tai Chi
– Fun
– Schedule “life” breaks
– Emotional release techniques
– Professional therapy
www.DepkeWellness.com
Moving Forward w/Support
• Exercise
– Chiropractic Care
– Anaerobic activity
• Weight training
• Stretching
• Pilates
• Gentle flow yoga
• Casual walk or bike ride
• Burst training
– Aerobic activity
• Reduce significantly or
eliminate
www.DepkeWellness.com
Moving Forward w/Support
• Testing
– Adrenal testing
– C-reactive protein (CRP)
– A1C
– Homocysteine
– GI pathogen screening
– Food sensitivities
• Supplementation
– Gut support
– Immune Support
– Adrenal support
– Anti-inflammatories
www.DepkeWellness.com
Moving Forward w/Support
L-Glutamine
• Address the four feedback loops
– Leaky gut
– Immune support
– Liver support
– Weight loss
www.DepkeWellness.com
Moving Forward w/Support
The PAIN of Inflammation Program
• Anti Inflammatory Meal Plan
– Remove all potential inflammatory
foods or foods that were tested via
blood testing
– Consume as much allowable foods
as desired but not overfull
– Follow your Nutritional ID
percentages
– Eat according to your Nutritional ID
as much as possible
– Eat as often as needed prior to
getting hungry
The PAIN of Inflammation Program
• Anti Inflammatory
Supplement Plan
– Turmero
– Resvero
– Ultra D
– Glutathione Recycler
– Nitric Balance
– GI Synergy
– Repairvite
– Hepato - Synergy
– Clearvite - PSF
• Deeper focus with every patient
• Improved results with spinal adjustments
• Accelerated improvement in patient health
• Increased revenue for your practice
– Focus on patients one on one
– Create group programs in your office
– Create group programs online
• Potential HRV recognition
It’s a Win/Win for Your
Practice
HRV Interpretation
• HRV is a constant evaluation
necessary to track the
combined approach of
adaptive responses.
• Chiropractic is the essential
foundation behind the
adjunctive wellness
strategies. Indeed
adjustments alone are not
the final answer.
• Chiropractic “sets the table
for health and wellness”
It’s All About You!
An Empowering Partnership

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Glen Depke:The Adrenal, Immunity, Inflammatory Trilogy

  • 1.
  • 2. The Adrenal, Immune, Inflammatory Trilogy HRV Interpretation by Glen Depke, Traditional Naturopath
  • 4. • HRV Interpretation • Chiropractic Care • Functional Recovery Program • Business Models The Healing Trilogy
  • 5. • Brain/Hypothalamus • Pituitary • Adrenal • Thymus • Thyroid • Pancreas • Ovary • Testicle • Pineal • Spinal column www.DepkeWellness.com Neuroendocrine System
  • 6. • Reviewed over 4,600 adrenal saliva test kits • These statistics are based on individuals with some type of health challenge • I have seen only 5 people test in the normal range • Approximately 1/10th of 1 percent were actually in a normal range • If you are not testing adrenal function, you are leaving people in the dark Percentage of Health Challenged Individuals with Adrenal Insufficiency
  • 8. Affects of Stress (High Cortisol)  Accelerates aging  Hypertension  Immune dysfunction  Subluxation  Fatigue  Protein deficiency  Insulin resistance  Weight gain  Muscle breakdown  Osteoporosis  Inhibits human growth hormone  Neuron death  Depression  Hippocampus dysfunction  Poor memory  Insomnia  PMS  Hypothalamus dysfunction  Menopause symptoms  Infertility  Impairs healing of wounds  Destroys tryptophan  Inhibits testosterone  Decreased glutamine www.DepkeWellness.com
  • 10. Cortisol Pregnenolone B5Acetyl CoA Cholesterol Androstenedione 19 - Hydroxy - androstenedione Estrone Estradiol - 17β 17α - Hydroxylation Testosterone 5α - Dihydro - testosterone 19 - Hydroxy - testosterone Estradiol - 17α Progesterone 17 - Hydroxyprogesterone 11 - Deoxycortisol Cortisone Adrenal Stress Response Androstenediol 17- Hydropregnenolone Dehydro - epiandrosterone www.DepkeWellness.com
  • 11. Triggers for Adrenal Insufficiency • Mental/emotional • Subluxation • Nutritional – SAD – Food Intolerance • Chemical – Toxins – Emotional response • Inflammation • Infection
  • 12. Stress Response Gone Too Far • Diabetes Mellitus • Cardiovascular Disease, High Blood Pressure, Elevated Blood Fats • Infertility, PMS, Menopause Symptoms • Autoimmune disease • Chronic inflammation • Osteoporosis • CFS/Fibromyalgia • Cancer • Chronic Illness www.DepkeWellness.com
  • 13. Assess Your Likelihood of Adrenal Fatigue • Take your complimentary adrenal stress profile assessment • What’s your score? • How I use this in my practice. www.DepkeWellness.com
  • 14. Reduce or Eliminate Your Triggers • Laugh and play • Chiropractic adjustments • Learn empowering emotional release • Eat well and eliminate food sensitivity • Reduce your toxic load • Create and anti- inflammatory effect • Assess and eliminate infection www.DepkeWellness.com
  • 15. Proper Supplement Support • Vitamin B5 (Pantothenic Acid) • Zinc • Vitamin C • B-Complex • Ashwagandha • Magnesium • Pregnenolone • DHEA www.DepkeWellness.com
  • 16. Nutritional Support • Digestive Function • Chiropractic • Food Sensitivity • Nutritional ID www.DepkeWellness.com
  • 17. Assisting Adrenal Function • Look for signs • Heart Rate Variability • Use your complimentary assessment • Testing adrenal function (saliva) • Reduce or eliminate triggers • Balancing Adrenals • Enjoy improved health and happiness www.DepkeWellness.com
  • 18. • Deeper understanding of every patient • Improved results with spinal adjustments • Accelerated improvement in patient health • Increased revenue for your practice – 10 Adrenal test kits weekly – 10 follow up consultations – Basic supplementation for each patient – Continued follow up appointments, testing and supplements It’s a Win/Win for Your Practice
  • 19. • Minimum yearly revenue increase based on 10 adrenal test kits weekly – Adrenal test kit revenue $237,120.00 – Follow up consultation $166,400.00 – Basic supplement recommendations $320,320.00 – Minus cost of testing -$205,920.00 – Minus cost of supplements -$160,160.00 – Staffing cost -$83,200.00 – Minimum Net income $274,560.00 It’s a Win/Win for Your Practice
  • 20. HRV Interpretation • HRV is a constant evaluation necessary to track the combined approach of adaptive responses. • Chiropractic is the essential foundation behind the adjunctive wellness strategies. Indeed adjustments alone are not the final answer. • Chiropractic “sets the table for health and wellness”
  • 21. www.DepkeWellness.com The Dead End of Many Functional Medicine Practices
  • 22. • Introduce the symptoms of chronic inflammation • Describe the importance and influence of NF-kB state • Identify potential inflammatory triggers • Identify and explain chronic inflammatory feedback loops • Expose the functional medicine dead end • Assist in understanding chronic inflammation out of control • Discuss moving forward to support the body in overcoming chronic inflammation www.DepkeWellness.com The PAIN of Inflammation
  • 23. • Does it take you a bit to get moving in the morning • Do you feel aches and pains with regularity • Are you stiff getting up from your desk • Are you challenged with chronic disease • Do you feel that your belly is bloated • Has weight gain been an issue for you • Are you feeling fatigued and frustrated www.DepkeWellness.com Early Signs of Chronic Inflammation?
  • 24. Did you know that most with chronic inflammation is not diagnosed until this is already a significant health issue? www.DepkeWellness.com The PAIN of Inflammation
  • 25. The PAIN of Inflammation • Did you know that approximately 116 million Americans suffer with chronic pain, which is about 1/3 of our country? • Recognize that chronic pain is almost always tied into chronic inflammation. • What is your PAIN? www.DepkeWellness.com
  • 26. • acid reflux/heartburn • acne • allergies/sensitivities • Alzheimer’s disease • asthma • atherosclerosis • bronchitis • cancer • celiac disease • chronic pain • autoimmunity • Crohn’s disease • cirrhosis • colitis • dementia • dermatitis • diabetes • dry eyes • edema • emphysema www.DepkeWellness.com Symptoms Associated with Chronic Inflammation
  • 27. • eczema • fibromyalgia • gastroenteritis • gingivitis • heart disease • hepatitis • high blood pressure • insulin resistance • interstitial cystitis • obesity • joint pain/ arthritis/ rheumatoid arthritis • metabolic syndrome (syndrome X) • myositis • nephritis • osteopenia • osteoporosis • Parkinson’s disease • periodontal disease www.DepkeWellness.com Symptoms Associated with Chronic Inflammation
  • 28. • polychondritis • psoriasis • scleroderma • sinusitis • Sjögren’s syndrome • spastic colon • systemic candidiasis • tendonitis • UTI’s • vaginitis www.DepkeWellness.com Symptoms Association with Chronic Inflammation
  • 29. Healthy Immune/Inflammatory Reaction www.DepkeWellness.com Stress Food Infection Immune Reaction Inflammation Adrenal Function
  • 30. • Nutritional – SAD – Food sensitivity • GI challenges – Infections • Stress • Subluxation • Obesity • Chemotherapy • Toxicity www.DepkeWellness.com Main Inflammatory Triggers
  • 31. www.DepkeWellness.com The Functional Medicine Dead End Stress Food Infection Adrenal Function Inflammation Omega 3’s
  • 32. www.DepkeWellness.com NF-kB Out of Control NF-kB Increased Fat Cells Leaky Gut Cytokine Release Hepatic Disruption
  • 33. • Nuclear Factor Kappa Beta – A protein complex that controls the transcription of DNA – It is found in all cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals and antigens – Controls the expression of genes encoding the pro- inflammatory cytokines, chemokines, adhesion molecules, inducible enzymes (COX-2 and iNOS) and growth factors – Chronically elevated NF-kB is linked to cancer, inflammatory conditions and autoimmunity www.DepkeWellness.com What is NF-kB?
  • 34. • Increase in fat cell production • Insulin resistance • Insulin surges • More inflammation www.DepkeWellness.com NF-kB Feedback Loops
  • 35. • Tight junction breakdown • Leaky gut • Immune activation • More inflammation www.DepkeWellness.com NF-kB Feedback Loops
  • 36. • Suppression of cytochrome P450 • Hepatic (liver) biotransformation • Activated liver end products • Add environmental triggers and… • More inflammation www.DepkeWellness.com NF-kB Feedback Loops
  • 37. • Immune cell activation • Cytokine release • Self-amplifying loop • Autoimmunity • More inflammation www.DepkeWellness.com NF-kB Feedback Loops
  • 39. • Inflammatory triggers • Chronic Inflammation/ NF-kB • Neurotransmitter Bradykinin • PAIN www.DepkeWellness.com The PAIN of Inflammation
  • 40. • Nutrition – Food Sensitivity • Blood Testing • Food elimination diets – Standard American Diet (SAD) • Significantly reduce or sugar and processed foods • Reduce or eliminate alcohol consumption • Eliminate gluten and/or other food sensitivities • Eat according to your Nutritional ID www.DepkeWellness.com Moving Forward w/Support
  • 41. • Chronic stress – Chiropractic Adjustments – Deep breathing – Meditation – Prayer – Yoga – Tai Chi – Fun – Schedule “life” breaks – Emotional release techniques – Professional therapy www.DepkeWellness.com Moving Forward w/Support
  • 42. • Exercise – Chiropractic Care – Anaerobic activity • Weight training • Stretching • Pilates • Gentle flow yoga • Casual walk or bike ride • Burst training – Aerobic activity • Reduce significantly or eliminate www.DepkeWellness.com Moving Forward w/Support
  • 43. • Testing – Adrenal testing – C-reactive protein (CRP) – A1C – Homocysteine – GI pathogen screening – Food sensitivities • Supplementation – Gut support – Immune Support – Adrenal support – Anti-inflammatories www.DepkeWellness.com Moving Forward w/Support L-Glutamine
  • 44. • Address the four feedback loops – Leaky gut – Immune support – Liver support – Weight loss www.DepkeWellness.com Moving Forward w/Support
  • 45. The PAIN of Inflammation Program • Anti Inflammatory Meal Plan – Remove all potential inflammatory foods or foods that were tested via blood testing – Consume as much allowable foods as desired but not overfull – Follow your Nutritional ID percentages – Eat according to your Nutritional ID as much as possible – Eat as often as needed prior to getting hungry
  • 46. The PAIN of Inflammation Program • Anti Inflammatory Supplement Plan – Turmero – Resvero – Ultra D – Glutathione Recycler – Nitric Balance – GI Synergy – Repairvite – Hepato - Synergy – Clearvite - PSF
  • 47. • Deeper focus with every patient • Improved results with spinal adjustments • Accelerated improvement in patient health • Increased revenue for your practice – Focus on patients one on one – Create group programs in your office – Create group programs online • Potential HRV recognition It’s a Win/Win for Your Practice
  • 48. HRV Interpretation • HRV is a constant evaluation necessary to track the combined approach of adaptive responses. • Chiropractic is the essential foundation behind the adjunctive wellness strategies. Indeed adjustments alone are not the final answer. • Chiropractic “sets the table for health and wellness”

Notas do Editor

  1. The hypothalamus is known as the master switchboard because it’s the part of the brain that controls the endocrine system. The pituitary gland, which hangs by a thin stalk from the hypothalamus, is called the master gland of the body because it regulates the activity of the endocrine glands.
  2. Based on 520 people with 2 test kits, yearly supplements, 2 sessions and the cost of the adrenal consultant at 50%.
  3. abnormal mobility of the coccyx which may trigger a chronic inflammatory process leading to degeneration of this structure