2. Learning Objectives
1.) Name the layers of the epidermis.
2.) Name appendages within the dermis.
3.) List the major functions of the skin.
4.) Name components of the pilosebaceous unit.
5.) Name the three stages of hair growth.
3. Integumentary system
The skin and its accessory organs
Sebaceous glands
Sudoriferous glands
Sensory perceptors
Hair
Nails
4. Pilosebaceous unit
The hair follicle and its appendages
Internal and external root sheaths
Hair shaft
Dermal papilla
Sebaceous gland
Arrector pili muscle
5. Overall Look at Skin
Body’s largest organ
Up to 20 square feet on the average person
Made of epithelial tissue and connective tissue
Epithelial – forms thin protective layer
Connective – binds, protects, cushions, & supports
3 main layers
Epidermis
Dermis
Subcutis or subcutaneous layer
6. Epidermis
“Horny Zone” Cells divide in the lowest
Stratum Corneum layer
Migrate up to replace dead
Stratum Lucidum
cells that have been shed
Stratum Granulosum As they move up, they are
“Germinal Zone” filled with keratin to protect
Stratum Spinosum against invasion
(keratinization)
Stratum Germinativum
7. Stratum Corneum
A.K.A – “horny layer”
Outermost layer of dead skin cells
Constantly shedding
Mostly bound by sebum
Sebum – fatty or oily secretion of sebaceous gland; serves as
lubrication
8. Stratum Lucidum
Below stratum corneum
Cells allow light to pass through them
Only present in palms of hands and soles of feet, where
epidermis is thickest
Purpose unknown
9. Stratum Granulosum
AKA – “granular layer”
Cells are living
As cells are pushed upward, lose nuclei and die
Gives skin opaque appearance
Varies in thickness
Persistent friction and pressure cause areas to thicken for
protection and form calluses
10. Stratum Spinosum
AKA – “Prickle cell layer”
Made of living cells
Attached to each other by prickly shaped fibers
11. Stratum Germinativum
Lowest layer of epidermis
Mitosis (cell division) occurs here
Cells migrate up, replacing dead skin cells that have been
shed
Desquamation (exfoliating dead skin cells) takes about 28
days
Stratum mucosum – single cell layer
12. Stratum Germinativum
Contains melanocytes
UV rays react with amino acid tyrosine found in melanocytes to
produce melanin
Melanin
Dark pigment gives skin color and protects dermis from UV
radiation and sun damage
13. Skin Color
Skin color depends on melanin
People have same number of melanocytes
Dark skin – melanocytes are more active, producing more
melanin
14. Dermis
Living layer or “true skin”
Made of dense connective tissue
Divided into two layers
Papillary layer
Reticular layer
15. Papillary layer
Made of fibers called papillae
Connects epidermis and dermis
Superficial capillaries looped around papillae
Nerve endings sensitive to touch
This layer forms the connective tissue sheath around hair
follicles.
16. Reticular Layer
Thickest layer of skin
Dense bundles of collagen fibers
Fibers are denser closer to papillary layer and thin as they near the
fatty subcutaneous tissue
Appendages
Arrector pili muscles
Blood vessels
Fat cells
Hair follicles
Lymph vessels
Nerve endings
Sebaceous glands
Sudoriferous glands
17. Blood Supply
Arteries and veins circulate into the dermis and branch into
smaller capillaries at the hair follicles, the hair papillae, and
glands
Transports oxygen-rich blood and nutrients essential for:
Growth
Reproduction
Tissue repair
18. Lymph Supply
Lymph glands produce lymph
Contains waste products, salts, nitrogenous wastes
Carried through vessels to lymph nodes and fluid is filtered for
excretion
20. Types of Sudoriferous Glands
Apocrine
Found in genital area and armpits (axillae)
Create body odor
Believed to excrete pheromones
Eccrine
Found all over body
Increased numbers on forehead, palms, soles of feet
21. Sebaceous Glands
Found all over skin
Most often appendages to the hair follicles and open into the
shafts of the follicles
Produce waxy, oily substance called sebum which lubricates
skin
Most active during puberty
22. Nerve Endings
Carry impulses to the brain
Found at various levels, various shapes, depending on
purpose
Most superficial are responsible for touch
Close to surface is pain receptor
Below that are receptors for heat and cold
Deeper in dermis are pressure receptors
23. Hair
AKA – pilosebaceous unit
Found all over body except palms of hands and soles of feet
Most is invisible to naked eye
Denser on head and limbs, after puberty in groin area and
axillae (armpits)
Hair growth influenced by hormones and genetic inheritance
24. Subcutaneous Layer
Located at base of dermis
Layer of fatty tissue
AKA – subcutis; adipose tissue
Separates dermis from muscles and helps skin to move over
them
Contains arteries, veins, lymph, nerve endings, fat cells
25. Structure of Hair – Follicular Canal and
Sheaths
Follicular canal –
depression in the
skin that houses the
hair
External root sheath
– inner side of canal
26. Hair Shaft
Lined with epidermal tissue extends through dermis into
subcutaneous tissue
Epidermal cells produce follicle and hair matrix
Base of follicle widens into hair follicle bulb
Bulb – where hair grows; contains hair matrix which is where cell
division occurs
Hair matrix produces the hair and external and internal root sheath
27. Internal Root Sheath
Innermost layer of the
follicle
Can sometimes see on
tweezed hair
Looks like clump of
petroleum jelly
Protects hair up as far as
sebaceous gland
28. Dermal Papilla and Papillae
Dermal papilla – located at base of bulb
Layer of dermal tissue that attaches itself to the epidermis with
papillae
Papillae contain blood vessels – needed for nutrients and
hormones for growth
29. Arrector Pili Muscle
Attaches to the underside of the hair at the dermal papilla
and the hair shaft
Responsible for lifting the hair, trapping a layer of air on the
skin’s surface
assisting in heat regulation
fear and cold stimulate contraction
causes “goose bumps”
30. Sebaceous Gland
Attached to hair follicle and opens into shaft
Secretes sebum
Lubricates hair to prevent dryness and breakage
Lubricates epidermis to prevent dryness and to prevent
bacteria and germs from entering
31. Layers of the Hair
3 layers compose the hair:
1.) Cuticle
2.) Cortex
3.) Medulla
34. Medulla
Innermost layer
AKA – pith or marrow
Fine hair lacks medulla
Can be found in all wavy hair
General rule: curlier the hair, the stronger the medulla
36. Lanugo
AKA – fetal hair
Soft, downy hair on fetuses in utero and infants at birth,
covering bodies and scalp
May contain pigment, light or dark
Sheds a few weeks after birth
Permanent hair begins to grow in
37. Vellus – “peach fuzz”
Confused with lanugo; difference is vellus is present through
adulthood
Fine, short, often no pigment or medulla
Women believed to have 55% more vellus hair than men
38. Terminal
Longer, coarser hair that covers scalp, arms, legs, groin area,
axillae, and on faces, chests, and backs of men
Hair follicles can produce vellus or terminal hair.
Affected by:
Age
Genetics
Health
Hormonal changes of puberty, pregnancy, and
menopause
40. Anagen: The Growing Phase
Hair follicle at its deepest
Hair matrix active, surrounding the dermal papilla
Can be affected by health of the individual
Once hair reaches full length it can remain there, depending
on location, for varying amounts of time.
41. Catagen: The Transitional Phase
Follicle separates from dermal papilla and shrinks to 1/3 of
size
Thin cord of epidermal tissue attaching follicle to dermal
papilla retracts upward with the dermal papilla
Shortest hair growth stage
42. Telogen: The Resting Stage
Follicle is 1/3 of original size
Base looks like club
Bulb is usually white
Dermal papilla is separated from hair follicle and attached by
thin cord of epidermal cells; will be released by end of phase
43. Hair Growth
Incomplete science
Things we know:
Hair grows faster in the summer
Good health improve hair growth
Young people experience more hair growth
Increase in number of telogen hairs during illness, after
childbirth, and when experiencing stress.
44. Functions of the Skin
Largest sensory organ
Multiple functions:
Protection
Heat regulation
Excretion – discharging waste material
Secretion – producing and discharging substances from glands
Absorption – uptake of one substance into another
Sensation
Synthesis of Vitamin D
Hair plays important role in these functions.
45. Protection
Skin protects the body against the environment and invasion
of bacteria.
Skin is usually NOT sterile and is covered by bacteria
Noninvading and nonpathogenic bacteria
Built-in protective aid, ACID MANTLE
46. Acid Mantle
pH of 5 to 5.6
Created by the combined activity of sweat and sebaceous
glands
Perspiration is acidic and acts as bactericide (inhibits growth of
bacteria)
NOT TRUE of areas of higher perspiration (groin and axillae),
skin is softer and less acidity in excessive perspiration
47. Protection continued
When organism does invade skin, reactions (inflammation,
swelling, welts) occur.
Leucocytes are released and destroy the invading organism.
Reactions help to prevent spread of infection to surrounding
tissue.
48. Protection continued
Horny layer acts as barrier
Skin is waterproof (thanks in part to sebum)
Sebum prevents drying and cracking → prevents bacteria and
germs from entering
When intact, skin prevents harmful fluids from entering and
prevents water, blood, and lymph from leaving.
49. Protection continued
Stratum germinativum protects by containing melanocytes which
produce melanin
Melanin – the body’s own sunscreen which protects from harmful UV
radiation
Dark skin get better protection, few incidences of skin cancer
51. Protection by Lymphatic System
Lymphatic fluid and lymphocytes are produced in lymph
nodes.
Lymphocytes transported through lymph vessels
Engulf bacteria
Carried back to lymph nodes
Filtered and drained of waste products
52. Heat Regulation
Healthy body temperature of 98°F or 37°C
Skin helps body to adjust and maintain a safe temperature
Evaporation
Perspiration
Radiation
Insulation
53. Heat Regulation – Evaporation and
Perspiration
Evaporation of perspiration produces cooling (AKA
thermoregulation).
54. Heat Regulation - Radiation
Radiation from constriction or dilation of capillaries affect
body temperature.
Dilation (expansion) causes surface heat of body to be reduced
through radiation. Causes flushed appearance.
Constriction (contraction) slows blood flow, preserving heat.
Gives skin bluish tint.
55. Heat Regulation - Insulation
Arrector pili muscle contracts, lifts hair, trapping a layer of
insulating air on skin’s surface. (Air is the best insulator!)
Sebum lubricates hair, preventing it from breaking; allows
hair to do its job.
Adipose tissue acts as effective insulator, keeping body
warm.
56. Secretion and Excretion
Sebaceous glands – secrete sebum, skin’s natural lubricant
Sudoriferous glands – excrete salt, urea, and other waste
material during perspiration.
58. Absorption and Penetration
Skin can absorb oil- and fat-based substances
Pharmaceutical creams and lotions penetrate the dermis and
absorb into the blood supply
Require medical guidance and physicians’ prescriptions to be
obtained
59. Absorption and Penetration
Cosmoceuticals contain NO drugs or medications but could
cause drug reactions.
May have deeper absorption qualities than over-the-counter
cosmetics.
Obtained from and require professional guidance of
dermatologist, plastic surgeon, or skin-care professional.
60. 1.) What are the three main layers of the
skin?
Epidermis, dermis, and subcutis or subcutaneous layer.
61. 2.) Into which two zones is the epidermis
divided?
Horny zone and germinal zone.
62. 3.) Name two layers of the epidermis.
Stratum corneum,
stratum lucidum,
stratum granulosum,
stratum spinosum,
stratum germinativum.
63. 4.) In which layer are melanocytes found?
Stratum germinativum
64. 5.) What are the two layers of the dermis?
Papillary layer and reticular layer
65. 6.) What is a sudorific gland?
A sweat gland, or gland that excretes salt, urea, and other waste
material.
66. 8.) Where is the hair matrix?
In the hair follicle bulb
67. 9.) What are the three stages of hair
growth?
Anagen, catagen, and telogen
68. 10.) Name at least five functions of the
skin.
Protection, heat regulation, excretion, secretion, absorption,
sensation, synthesis of Vitamin D.