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A newsletter from the Hereditary Neuropathy Foundation - covers patient stories, research and fundraising on Charcot-Marie-Tooth
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Information from Jonahs just begun on their Chase Community giving challenge. Jill Wood provided the following fliers - please spread the word to raise votes for a worthy cause - Jonah and other children with Sanfilippo Syndrome
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A newsletter from the Hereditary Neuropathy Foundation - covers patient stories, research and fundraising on Charcot-Marie-Tooth
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Information from Jonahs just begun on their Chase Community giving challenge. Jill Wood provided the following fliers - please spread the word to raise votes for a worthy cause - Jonah and other children with Sanfilippo Syndrome
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Presentation from AAPS PharmSci360 (October 23, 2023) in which I describe highlights of my Springer/AAPS book Winning Grants (https://link.springer.com/book/10.1007/978-3-031-27516-6) - presenting a 'how to' guide on writing small business grants - e.g. NIH STTR and SBIR grants. Written by someone experienced in winning such grants.
How to Win a small business grant.pptx
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Sean Ekins
The presentation was given at SETAC 2022 Nov 16 and describes our work on Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic Toxicity. We generated many models that are available to license in our MegaTox software. We found that the support vector machines performed the best after assessing many algorithms for both classification and regression models. The authors of this work are Thomas R Lane, Fabio Urbina and Sean Ekins. The contact is sean@collaborationspharma.com
Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic To...
Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic To...
Sean Ekins
This presentation from June 12 2020 gives a brief overview of my experience of 15 years of applying for government grants to fund small companies. Prior to this I had no experience of applying for such grants. The bottom line for rare disease groups / families is find a scientist that can do this or assist you. please also see www.collaborationspharma.com
A presentation at the Global Genes rare drug development symposium on governm...
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Slides from AAPS Careers session by Maren Katherina Preis, Kyle Bagin, Sean Ekins Provides some clear steps on how you could use social media to help your career.
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Sean Ekins
Oral presentation given in MEDI session at 2017 ACS in DC. co-authors Kimberley M. Zorn, Mary A. Lingerfelt, Jair L. de Siqueira-Neto, Alex M. Clark, Sean Ekins describes drug repurposing and machine learning - for more details see www.collaborationspharma.com
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Oral presentation at 2017 ACS in DC - given by Kimberley Zorn co-authors include Mary A. Lingerfelt, Alex M. Clark, Sean Ekins for more details see www.collaborationspharma.com
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A special issue on tuberculosis drug research funded by the EU. With particular focus on MM4TB
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Presentation on Thursday 18 march 2016 a ACS National meeting. Session on BIG DATA. My last ACS presentation a the national meeting !
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A perspective on 12 yrs of CDD and developing products and collaborations. A presentation given at the ACS meeting in San Diego - small business section
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Riff on the economist cover March 2016 - with a huge debt to their graphic designer!
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This presentation summarizes some early efforts on an open drug discovery collaboration between scientists in Brazil and the US. The amazing virus images were created by John Liebler and can be licensed from him http://www.artofthecell.com/animation/will-the-real-zika-virus-please-stand-up The homology models were created with Swiss Model by Sean Ekins: Marco Biasini, Stefan Bienert, Andrew Waterhouse, Konstantin Arnold, Gabriel Studer, Tobias Schmidt, Florian Kiefer, Tiziano Gallo Cassarino, Martino Bertoni, Lorenza Bordoli, Torsten Schwede. (2014). SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information. Nucleic Acids Research; (1 July 2014) 42 (W1): W252-W258; doi: 10.1093/nar/gku340. Arnold K., Bordoli L., Kopp J., and Schwede T. (2006). The SWISS-MODEL Workspace: A web-based environment for protein structure homology modelling. Bioinformatics, 22,195-201. Kiefer F, Arnold K, Künzli M, Bordoli L, Schwede T (2009). The SWISS-MODEL Repository and associated resources. Nucleic Acids Research. 37, D387-D392. Guex, N., Peitsch, M.C., Schwede, T. (2009). Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective. Electrophoresis, 30(S1), S162-S173.
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Presentation from AAPS PharmSci360 (October 23, 2023) in which I describe highlights of my Springer/AAPS book Winning Grants (https://link.springer.com/book/10.1007/978-3-031-27516-6) - presenting a 'how to' guide on writing small business grants - e.g. NIH STTR and SBIR grants. Written by someone experienced in winning such grants.
How to Win a small business grant.pptx
How to Win a small business grant.pptx
Sean Ekins
The presentation was given at SETAC 2022 Nov 16 and describes our work on Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic Toxicity. We generated many models that are available to license in our MegaTox software. We found that the support vector machines performed the best after assessing many algorithms for both classification and regression models. The authors of this work are Thomas R Lane, Fabio Urbina and Sean Ekins. The contact is sean@collaborationspharma.com
Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic To...
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Sean Ekins
This presentation from June 12 2020 gives a brief overview of my experience of 15 years of applying for government grants to fund small companies. Prior to this I had no experience of applying for such grants. The bottom line for rare disease groups / families is find a scientist that can do this or assist you. please also see www.collaborationspharma.com
A presentation at the Global Genes rare drug development symposium on governm...
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Sean Ekins
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Leveraging Science Communication and Social Media to Build Your Brand and Ele...
Sean Ekins
Oral presentation given in MEDI session at 2017 ACS in DC. co-authors Kimberley M. Zorn, Mary A. Lingerfelt, Jair L. de Siqueira-Neto, Alex M. Clark, Sean Ekins describes drug repurposing and machine learning - for more details see www.collaborationspharma.com
Bayesian Models for Chagas Disease
Bayesian Models for Chagas Disease
Sean Ekins
Oral presentation at 2017 ACS in DC - given by Kimberley Zorn co-authors include Mary A. Lingerfelt, Alex M. Clark, Sean Ekins for more details see www.collaborationspharma.com
Assay Central: A New Approach to Compiling Big Data and Preparing Machine Lea...
Assay Central: A New Approach to Compiling Big Data and Preparing Machine Lea...
Sean Ekins
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Drug Discovery Today March 2017 special issue
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Sean Ekins
Presentation given at the AAPS meeting 2016 in Denver in a session on repurposing. I describes several recent published studies and unpublished work.
Using In Silico Tools in Repurposing Drugs for Neglected and Orphan Diseases
Using In Silico Tools in Repurposing Drugs for Neglected and Orphan Diseases
Sean Ekins
Presentation given at the AAPS 2016 conference in Denver. Some of the slides are from AAPS, Some from Kudos and some from Figshare. One slide is from Tony Williams. All slides used with permission.
Five Ways to Use Social Media to Raise Awareness for Your Paper or Research
Five Ways to Use Social Media to Raise Awareness for Your Paper or Research
Sean Ekins
These slides provide a complete and upto date analysis of the project and complement the recent article in PLOS Neglected Tropical Diseases
Open zika presentation
Open zika presentation
Sean Ekins
Talk at Science in the age of experience May 2016 - boston
academic / small company collaborations for rare and neglected diseasesv2
academic / small company collaborations for rare and neglected diseasesv2
Sean Ekins
A Case study for CDD Models using a kinase dataset in a secure CDD Vault
CDD models case study #3
CDD models case study #3
Sean Ekins
Using Schistosoma mansoni data to demonstrate CDD Models - a test case to illustrate their use in a secure vault
CDD models case study #2
CDD models case study #2
Sean Ekins
Using AZ ADME data to demonstrate CDD Models - a test case to illustrate their use in a secure vault
CDD Models case study #1
CDD Models case study #1
Sean Ekins
Presentation on Thursday 18 march 2016 a ACS National meeting. Session on BIG DATA. My last ACS presentation a the national meeting !
Using Machine Learning Models Based on Phenotypic Data to Discover New Molecu...
Using Machine Learning Models Based on Phenotypic Data to Discover New Molecu...
Sean Ekins
A perspective on 12 yrs of CDD and developing products and collaborations. A presentation given at the ACS meeting in San Diego - small business section
CDD: Vault, CDD: Vision and CDD: Models software for biologists and chemists ...
CDD: Vault, CDD: Vision and CDD: Models software for biologists and chemists ...
Sean Ekins
Riff on the economist cover March 2016 - with a huge debt to their graphic designer!
The future of computational chemistry b ig
The future of computational chemistry b ig
Sean Ekins
This presentation summarizes some early efforts on an open drug discovery collaboration between scientists in Brazil and the US. The amazing virus images were created by John Liebler and can be licensed from him http://www.artofthecell.com/animation/will-the-real-zika-virus-please-stand-up The homology models were created with Swiss Model by Sean Ekins: Marco Biasini, Stefan Bienert, Andrew Waterhouse, Konstantin Arnold, Gabriel Studer, Tobias Schmidt, Florian Kiefer, Tiziano Gallo Cassarino, Martino Bertoni, Lorenza Bordoli, Torsten Schwede. (2014). SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information. Nucleic Acids Research; (1 July 2014) 42 (W1): W252-W258; doi: 10.1093/nar/gku340. Arnold K., Bordoli L., Kopp J., and Schwede T. (2006). The SWISS-MODEL Workspace: A web-based environment for protein structure homology modelling. Bioinformatics, 22,195-201. Kiefer F, Arnold K, Künzli M, Bordoli L, Schwede T (2009). The SWISS-MODEL Repository and associated resources. Nucleic Acids Research. 37, D387-D392. Guex, N., Peitsch, M.C., Schwede, T. (2009). Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective. Electrophoresis, 30(S1), S162-S173.
#ZikaOpen: Homology Models -
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Sean Ekins
Ensuring Chemical Structure, Biological Data and Computational Model Quality A talk given at SLAS 2016 mon Jan 25th in San Diego covers published work and recent forays with BIA 10-2474
Slas talk 2016
Slas talk 2016
Sean Ekins
Over the past 4 years I have been using social networking tools for scientists more inspired by Antony Williams. I realized I am using many tools and there are pros and cons of them. Here is my brief summary.
Pros and cons of social networking for scientists
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Sean Ekins
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How to Win a small business grant.pptx
How to Win a small business grant.pptx
Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic To...
Evaluating Multiple Machine Learning Models for Biodegradation and Aquatic To...
A presentation at the Global Genes rare drug development symposium on governm...
A presentation at the Global Genes rare drug development symposium on governm...
Leveraging Science Communication and Social Media to Build Your Brand and Ele...
Leveraging Science Communication and Social Media to Build Your Brand and Ele...
Bayesian Models for Chagas Disease
Bayesian Models for Chagas Disease
Assay Central: A New Approach to Compiling Big Data and Preparing Machine Lea...
Assay Central: A New Approach to Compiling Big Data and Preparing Machine Lea...
Drug Discovery Today March 2017 special issue
Drug Discovery Today March 2017 special issue
Using In Silico Tools in Repurposing Drugs for Neglected and Orphan Diseases
Using In Silico Tools in Repurposing Drugs for Neglected and Orphan Diseases
Five Ways to Use Social Media to Raise Awareness for Your Paper or Research
Five Ways to Use Social Media to Raise Awareness for Your Paper or Research
Open zika presentation
Open zika presentation
academic / small company collaborations for rare and neglected diseasesv2
academic / small company collaborations for rare and neglected diseasesv2
CDD models case study #3
CDD models case study #3
CDD models case study #2
CDD models case study #2
CDD Models case study #1
CDD Models case study #1
Using Machine Learning Models Based on Phenotypic Data to Discover New Molecu...
Using Machine Learning Models Based on Phenotypic Data to Discover New Molecu...
CDD: Vault, CDD: Vision and CDD: Models software for biologists and chemists ...
CDD: Vault, CDD: Vision and CDD: Models software for biologists and chemists ...
The future of computational chemistry b ig
The future of computational chemistry b ig
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#ZikaOpen: Homology Models -
Slas talk 2016
Slas talk 2016
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