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Evaluation of nasolacrimal system




                  Balasubramanian Thiagarajan




Autor: 17.09.12
Why should we bother?
  ●   Otolaryngologists perform endoscopic
      dacryocystorhinostomy more and more
  ●   Helps in deciding whether the patient will benefit
      from this procedure
  ●   Operating surgeon should clinically examine
      patients before surgery




Autor: 17.09.12
History
                      ●   Anatomy of
                          nasolacrimal pathway –
                          Hamurabi 2200 BC
                      ●   Endo-DCR first
                          described by Caldwell
                          1893
                      ●   External DCR – Toti in
                          1904



Autor: 17.09.12
Epiphora (Downpour)
  ●   Excessive lacrimation
  ●   Defective drainage
  ●   Lacrimal pump failure




Autor: 17.09.12
Classification of Epiphora
  ●   Congenital causes
  ●   Acquired causes




Autor: 17.09.12
Congenital
  ●   1% of infants
  ●   Self limiting disorder
  ●   Massaging of the sac helps
  ●   Probing beneficial




Autor: 17.09.12
Acquired
  ●   Primary acquired nasolacrimal duct obstruction
  ●   Dacryocystolithiasis
  ●   Orbital / lacrimal trauma
  ●   Canalicular lacerations
  ●   Actinomyces within canaliculi
  ●   Canalicular lesions following herpes / antiviral
      therapy (+ h/o keratoconjunctivitis)


Autor: 17.09.12
Anatomical obstruction
  ●   Pathologies involving sac
  ●   Canalicular stenosis / blockage
  ●   Obstruction to nasolacrimal duct
  ●   Formation of diverticula




Autor: 17.09.12
Types of obstruction
  ●   Intrinsic – caused by internal derangements of the
      mucosal lining of lacrimal apparatus
  ●   Extrinsic – Caused by extraneous deforming lesions
      which can deform the drainage channel as is the
      case in tumors.




Autor: 17.09.12
Epiphora (Physiologic)
  ●   No anatomical changes in the lacrimal pathway
  ●   Lacrimal pump mechanism is at fault
  ●   Eye lid malpositions, eversion of punctum, poor
      orbicularis oculi muscle tone
  ●   Bell's palsy




Autor: 17.09.12
Epiphora Grading (Sahlin)


                   Grade              Degree of epiphora
0                             No epiphora
1                             Epiphora only outdoors and during
                              windy times

2                             Outdoor epiphora No indoor
                              epiphora

3                             Outdoor and indoor epiphora




Autor: 17.09.12
Anatomy of lacrimal system
                               ●   Nasolacrimal duct is
                                   18mm long
                               ●   Junction between
                                   common canaliculus
                                   and sac is guarded by
                                   Rosenmuller valve




Autor: 17.09.12
Sites of lacrimal system block
  ●   Suprasaccal
  ●   Saccal
  ●   Subsaccal




Autor: 17.09.12
Suprasaccal obstruction
                              ●   Obstruction is proximal
                                  to sac
                              ●   Upper canaliculus
                              ●   Lower canaliculus
                              ●   Common canaliculus
                              ●   Herpes infection,
                                  trauma, irradiation



Autor: 17.09.12
Saccal obstruction
                           ●   Obstruction at the level
                               of sac
                           ●   Tumor
                           ●   Diverticula
                           ●   Trauma




Autor: 17.09.12
Subsaccal obstruction




       Incomplete             Compete

Autor: 17.09.12
Functional obstruction
  ●   Lacrimal system is patent to syringing still there is
      epiphora
  ●   Obstruction is to be used only for anatomical
      obstruction




Autor: 17.09.12
Causes of excessive tearing
  ●   Hypersecretion
  ●   Epiphora
  ●   Combination of both




Autor: 17.09.12
Diagnostic evaluation
  ●   Quantification of tear production
  ●   Assessment of nasolacrimal system patency
  ●   Differentiating epiphora from lacrimation
  ●   Defining the pathological process
  ●   Differentiating anatomical from functional
      obstruction
  ●   Attempting to locate the site of obstruction


Autor: 17.09.12
Classification of tests to evaluate
              lacrimal system pathway
  ●   Anatomical tests
  ●   Functional tests
  ●   Secretory tests




Autor: 17.09.12
Anatomical tests
  ●   These tests helps in localization of obstruction
  ●   Palpation of sac
  ●   Syringing / irrigation
  ●   Diagnostic probing
  ●   Dacryocystography
  ●   Nasal exam
  ●   CT/MRI


Autor: 17.09.12
Functional tests
  ●   To access functioning of lacrimal apparatus under
      physiologic conditions
  ●   Performed only when there is no evidence of
      obstruction in anatomical tests




Autor: 17.09.12
Functional tests (contd)
  ●   Flourescein dye disappearance test
  ●   Scintigraphy
  ●   Jones dye test I
  ●   Sacharin test




Autor: 17.09.12
Tests for lacrimal secretions
  ●   These tests are performed to access secretory
      functions of lacrimal apparatus
  ●   Schrimers test
  ●   Bengal Rose test
  ●   Tear-film break up
  ●   Tear lysozyme




Autor: 17.09.12
Causes of excess lacrimation
  ●   Supranuclear causes – Psychogenic / emotions
  ●   Stimulation of V nerve
  ●   Infranuclear causes
  ●   Lacrimal gland stimulation
  ●   Other causes – Bright lights / sneezing




Autor: 17.09.12
Stimulation of V nerve
  ●   Reflex tearing
  ●   Lid causes – Blepharitis / trichiasis
  ●   Conjunctival diseases
  ●   Corneal diseases
  ●   Neuralgia
  ●   Ocular inflammation



Autor: 17.09.12
Infranuclear causes
  ●   Facial palsy
  ●   Aberrant innervation
  ●   Crocodile tears




Autor: 17.09.12
Epiphora causes
  ●   Functional insufficiency – incorrect lid closure, lid
      malposition, punctal eversion, punctal medialization
  ●   Anatomical obstruction
  ●   Combination of functional insufficiency and
      anatomical obstruction




Autor: 17.09.12
Combined epiphora
  ●   Facial nerve palsy – corneal irritation and pump
      defects
  ●   Lower lid ectropion – conjunctival irritation and
      pump defects
  ●   Thyroid diseases – corneal irritation and defective
      canalicular function




Autor: 17.09.12
History taking
  ●   Provides vital clues to the presence of canalicular
      disorders
  ●   H/o present /past opthalmological problems
  ●   Nasal symptoms
  ●   Previous surgeries
  ●   Unilateral tearing – obstruction
  ●   Bilateral tearing - Physiological`


Autor: 17.09.12
Inspection & palpation
  ●   Eye lids
  ●   Medial canthus
  ●   Palpation of sac




Autor: 17.09.12
Eye lid examination
  ●   Lower lid laxity
  ●   Ectropion
  ●   Punctal eversion
  ●   Trichiasis
  ●   Blepharitis




Autor: 17.09.12
Snap back test
  ●   Test for lower lid laxity
  ●   Lower lid is pulled down and away from the orbit
  ●   On release the lid resumes normal position
  ●   Time taken for the lid to get back to normal postion
      is noted
  ●   Longer the duration more lax is the lower lid
  ●   Graded over a scale of 0-4


Autor: 17.09.12
Lid examination (contd)
  ●   Medial canthal laxity
  ●   Lateral canthal laxity
  ●   Orbicularis oculi muscle tone check




Autor: 17.09.12
Examination of medial canthus




      Neoplasm               Sac enlargement

Autor: 17.09.12
Sac palpation

                        ●   Normal sac not palpable
                        ●   Sac is palpable below
                            the medial canthus
                        ●   Reflux of tears / pent up
                            secretions
                        ●   Pain / tenderness –
                            acute dacryocystitis



Autor: 17.09.12
Dye excretion test
  ●   Drainage function of entire lacrimal apparatus can
      be tested
  ●   Fluorescein dye is used for this purpose
  ●   This test is more physiological
  ●   This test does not differentiate anatomical from
      physiological causes of nasolacrimal obstruction




Autor: 17.09.12
Fluorescein dye test
  ●   1% fluorescein is instilled into the conjunctiva
  ●   Conjunctiva is not anaesthetized
  ●   After 5 mins thickness of fluorescein of the tear
      meniscus is measured using cobalt blue filter
  ●   This test can be safely performed in infants &
      children




Autor: 17.09.12
Fluorescein dye test (contd)
  ●   Presence of residual fluorescein gives no
      information regarding localisation of block
  ●   Presence of residual fluorescein is an indication for
      probing and syringing
  ●   When performing this test in children they should be
      held in vertical postion




Autor: 17.09.12
Dye test grading
  ●   0=No fluorescein in the conjunctival sac
  ●   1=Thin flurescing marginal tear drop persists
  ●   2=More fluorescein persists somewhere between 1
      and 3 grades
  ●   3=Wide brightly fluorescein tear strip
  ●   Grades 0 and 1 are considered normal




Autor: 17.09.12
False negative dye test
      1. Large lacrimal sac
      2. Mucocele
      3. Distal nasolacrimal duct block




Autor: 17.09.12
Break up time test
  ●   Performed by placing a drop of fluorescein in the
      outer canthus of the eye
  ●   Its transport can be observed from lateral to medial
  ●   Holes in the tear film can also be observed
  ●   Normal breakup time is 15-30 secs
  ●   Breakup time of less than 10 secs indicate epiphora




Autor: 17.09.12
Jones dye test
                          ●   Distinguishes between
                              functional and
                              anatomical obstruction
                          ●   Topical xylocaine
                              application
                          ●   Flurescein dye instilled
                          ●   Negative result
                              indicates functional /
                              anatomical block
                          ●   Useless in total
Autor: 17.09.12               obstruction
Saccharin test

  ●   Similar to fluorescein dye test
  ●   Physiological
  ●   Saccharin is placed in conjunctiva
  ●   Saccharine taste appears within 3.5 mins
  ●   Pt should have normal taste sensation




Autor: 17.09.12
Probing & syringing
  ●   Invasive test
  ●   Provides information regarding site of obstruction
  ●   Useless in functional obstruction
  ●   This is not a physiological test
  ●   This test should be interpreted with fluorescein dye
      test and clinical examination




Autor: 17.09.12
Syringing (contd)
  ●   Topical xylocaine applied
  ●   Punctum dilator applied to dilate punctum
  ●   Tip of irrigator placed in the inferior canaliculus. It
      is directed first vertically and then horizontally.
      Eyelid is stretched
  ●   Tip is advanced 3-7 mm into canaliculus and saline
      is injected
  ●   Irrigation should not be forced


Autor: 17.09.12
Syringing (Interpretation)
  ●   Regurgitation through opposite punctum –
      obstruction in the common canaliculus or more
      distal structures
  ●   Regurgitation via the same punctum indicates
      punctal obstruction
  ●   Drainage via nose does not rule out physiological
      obstruction




Autor: 17.09.12
Diagnostic probing




    Hard stop                 Soft stop

Autor: 17.09.12
Irrigation / probing interpretation




Autor: 17.09.12
Radiological evaluation
  ●   Dacryocystography
  ●   Nuclear lacrimal scintigraphy
  ●   CT
  ●   MRI




Autor: 17.09.12
Dacryocystography
  ●   Anatomical investigation
  ●   Creates interior image of the entire lacrimal system
  ●   Radio opaque water soluble dye is injected into the
      canaliculus
  ●   Magnified images are created
  ●   Digital subtraction is used




Autor: 17.09.12
Radiologic criteria of lacrimal
                      pathology
  ●   Regurgitation of radio-opaque fluid into the
      conjunctival sac
  ●   Absence of fluid in the nose
  ●   Fluctuation of lumen of lacrimal system
  ●   Irregularity in contrast
  ●   Deformation involving lacrimal sac




Autor: 17.09.12
Nuclear lacrimal scintigraphy

  ●   Non invasive physiological test
  ●   Utilizes radiotracer technitium-99M pertechnitate.
  ●   Images can be captured using epiphora
  ●   Drop of technetium-99m instilled into conjunctiva
  ●   Recording is made using gamma camera
  ●   20 mins is the recording time



Autor: 17.09.12
CT/MRI
                      Helpful in identifying
                      adjacent areas and other
                      mass lesions




Autor: 17.09.12
Secretory tests
  ●   Schimer's test
  ●   Rose bengal test




Autor: 17.09.12
schirmer's test

                          ●   35x5 mm paper
                          ●   5 mins duration
                          ●   10-30 mm wetness
                              normal
                          ●   Above 30mm epiphora
                          ●   10mm dryness




Autor: 17.09.12
Thankyou




Autor: 17.09.12

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nasolacrimal system examination

  • 1. Evaluation of nasolacrimal system Balasubramanian Thiagarajan Autor: 17.09.12
  • 2. Why should we bother? ● Otolaryngologists perform endoscopic dacryocystorhinostomy more and more ● Helps in deciding whether the patient will benefit from this procedure ● Operating surgeon should clinically examine patients before surgery Autor: 17.09.12
  • 3. History ● Anatomy of nasolacrimal pathway – Hamurabi 2200 BC ● Endo-DCR first described by Caldwell 1893 ● External DCR – Toti in 1904 Autor: 17.09.12
  • 4. Epiphora (Downpour) ● Excessive lacrimation ● Defective drainage ● Lacrimal pump failure Autor: 17.09.12
  • 5. Classification of Epiphora ● Congenital causes ● Acquired causes Autor: 17.09.12
  • 6. Congenital ● 1% of infants ● Self limiting disorder ● Massaging of the sac helps ● Probing beneficial Autor: 17.09.12
  • 7. Acquired ● Primary acquired nasolacrimal duct obstruction ● Dacryocystolithiasis ● Orbital / lacrimal trauma ● Canalicular lacerations ● Actinomyces within canaliculi ● Canalicular lesions following herpes / antiviral therapy (+ h/o keratoconjunctivitis) Autor: 17.09.12
  • 8. Anatomical obstruction ● Pathologies involving sac ● Canalicular stenosis / blockage ● Obstruction to nasolacrimal duct ● Formation of diverticula Autor: 17.09.12
  • 9. Types of obstruction ● Intrinsic – caused by internal derangements of the mucosal lining of lacrimal apparatus ● Extrinsic – Caused by extraneous deforming lesions which can deform the drainage channel as is the case in tumors. Autor: 17.09.12
  • 10. Epiphora (Physiologic) ● No anatomical changes in the lacrimal pathway ● Lacrimal pump mechanism is at fault ● Eye lid malpositions, eversion of punctum, poor orbicularis oculi muscle tone ● Bell's palsy Autor: 17.09.12
  • 11. Epiphora Grading (Sahlin) Grade Degree of epiphora 0 No epiphora 1 Epiphora only outdoors and during windy times 2 Outdoor epiphora No indoor epiphora 3 Outdoor and indoor epiphora Autor: 17.09.12
  • 12. Anatomy of lacrimal system ● Nasolacrimal duct is 18mm long ● Junction between common canaliculus and sac is guarded by Rosenmuller valve Autor: 17.09.12
  • 13. Sites of lacrimal system block ● Suprasaccal ● Saccal ● Subsaccal Autor: 17.09.12
  • 14. Suprasaccal obstruction ● Obstruction is proximal to sac ● Upper canaliculus ● Lower canaliculus ● Common canaliculus ● Herpes infection, trauma, irradiation Autor: 17.09.12
  • 15. Saccal obstruction ● Obstruction at the level of sac ● Tumor ● Diverticula ● Trauma Autor: 17.09.12
  • 16. Subsaccal obstruction Incomplete Compete Autor: 17.09.12
  • 17. Functional obstruction ● Lacrimal system is patent to syringing still there is epiphora ● Obstruction is to be used only for anatomical obstruction Autor: 17.09.12
  • 18. Causes of excessive tearing ● Hypersecretion ● Epiphora ● Combination of both Autor: 17.09.12
  • 19. Diagnostic evaluation ● Quantification of tear production ● Assessment of nasolacrimal system patency ● Differentiating epiphora from lacrimation ● Defining the pathological process ● Differentiating anatomical from functional obstruction ● Attempting to locate the site of obstruction Autor: 17.09.12
  • 20. Classification of tests to evaluate lacrimal system pathway ● Anatomical tests ● Functional tests ● Secretory tests Autor: 17.09.12
  • 21. Anatomical tests ● These tests helps in localization of obstruction ● Palpation of sac ● Syringing / irrigation ● Diagnostic probing ● Dacryocystography ● Nasal exam ● CT/MRI Autor: 17.09.12
  • 22. Functional tests ● To access functioning of lacrimal apparatus under physiologic conditions ● Performed only when there is no evidence of obstruction in anatomical tests Autor: 17.09.12
  • 23. Functional tests (contd) ● Flourescein dye disappearance test ● Scintigraphy ● Jones dye test I ● Sacharin test Autor: 17.09.12
  • 24. Tests for lacrimal secretions ● These tests are performed to access secretory functions of lacrimal apparatus ● Schrimers test ● Bengal Rose test ● Tear-film break up ● Tear lysozyme Autor: 17.09.12
  • 25. Causes of excess lacrimation ● Supranuclear causes – Psychogenic / emotions ● Stimulation of V nerve ● Infranuclear causes ● Lacrimal gland stimulation ● Other causes – Bright lights / sneezing Autor: 17.09.12
  • 26. Stimulation of V nerve ● Reflex tearing ● Lid causes – Blepharitis / trichiasis ● Conjunctival diseases ● Corneal diseases ● Neuralgia ● Ocular inflammation Autor: 17.09.12
  • 27. Infranuclear causes ● Facial palsy ● Aberrant innervation ● Crocodile tears Autor: 17.09.12
  • 28. Epiphora causes ● Functional insufficiency – incorrect lid closure, lid malposition, punctal eversion, punctal medialization ● Anatomical obstruction ● Combination of functional insufficiency and anatomical obstruction Autor: 17.09.12
  • 29. Combined epiphora ● Facial nerve palsy – corneal irritation and pump defects ● Lower lid ectropion – conjunctival irritation and pump defects ● Thyroid diseases – corneal irritation and defective canalicular function Autor: 17.09.12
  • 30. History taking ● Provides vital clues to the presence of canalicular disorders ● H/o present /past opthalmological problems ● Nasal symptoms ● Previous surgeries ● Unilateral tearing – obstruction ● Bilateral tearing - Physiological` Autor: 17.09.12
  • 31. Inspection & palpation ● Eye lids ● Medial canthus ● Palpation of sac Autor: 17.09.12
  • 32. Eye lid examination ● Lower lid laxity ● Ectropion ● Punctal eversion ● Trichiasis ● Blepharitis Autor: 17.09.12
  • 33. Snap back test ● Test for lower lid laxity ● Lower lid is pulled down and away from the orbit ● On release the lid resumes normal position ● Time taken for the lid to get back to normal postion is noted ● Longer the duration more lax is the lower lid ● Graded over a scale of 0-4 Autor: 17.09.12
  • 34. Lid examination (contd) ● Medial canthal laxity ● Lateral canthal laxity ● Orbicularis oculi muscle tone check Autor: 17.09.12
  • 35. Examination of medial canthus Neoplasm Sac enlargement Autor: 17.09.12
  • 36. Sac palpation ● Normal sac not palpable ● Sac is palpable below the medial canthus ● Reflux of tears / pent up secretions ● Pain / tenderness – acute dacryocystitis Autor: 17.09.12
  • 37. Dye excretion test ● Drainage function of entire lacrimal apparatus can be tested ● Fluorescein dye is used for this purpose ● This test is more physiological ● This test does not differentiate anatomical from physiological causes of nasolacrimal obstruction Autor: 17.09.12
  • 38. Fluorescein dye test ● 1% fluorescein is instilled into the conjunctiva ● Conjunctiva is not anaesthetized ● After 5 mins thickness of fluorescein of the tear meniscus is measured using cobalt blue filter ● This test can be safely performed in infants & children Autor: 17.09.12
  • 39. Fluorescein dye test (contd) ● Presence of residual fluorescein gives no information regarding localisation of block ● Presence of residual fluorescein is an indication for probing and syringing ● When performing this test in children they should be held in vertical postion Autor: 17.09.12
  • 40. Dye test grading ● 0=No fluorescein in the conjunctival sac ● 1=Thin flurescing marginal tear drop persists ● 2=More fluorescein persists somewhere between 1 and 3 grades ● 3=Wide brightly fluorescein tear strip ● Grades 0 and 1 are considered normal Autor: 17.09.12
  • 41. False negative dye test 1. Large lacrimal sac 2. Mucocele 3. Distal nasolacrimal duct block Autor: 17.09.12
  • 42. Break up time test ● Performed by placing a drop of fluorescein in the outer canthus of the eye ● Its transport can be observed from lateral to medial ● Holes in the tear film can also be observed ● Normal breakup time is 15-30 secs ● Breakup time of less than 10 secs indicate epiphora Autor: 17.09.12
  • 43. Jones dye test ● Distinguishes between functional and anatomical obstruction ● Topical xylocaine application ● Flurescein dye instilled ● Negative result indicates functional / anatomical block ● Useless in total Autor: 17.09.12 obstruction
  • 44. Saccharin test ● Similar to fluorescein dye test ● Physiological ● Saccharin is placed in conjunctiva ● Saccharine taste appears within 3.5 mins ● Pt should have normal taste sensation Autor: 17.09.12
  • 45. Probing & syringing ● Invasive test ● Provides information regarding site of obstruction ● Useless in functional obstruction ● This is not a physiological test ● This test should be interpreted with fluorescein dye test and clinical examination Autor: 17.09.12
  • 46. Syringing (contd) ● Topical xylocaine applied ● Punctum dilator applied to dilate punctum ● Tip of irrigator placed in the inferior canaliculus. It is directed first vertically and then horizontally. Eyelid is stretched ● Tip is advanced 3-7 mm into canaliculus and saline is injected ● Irrigation should not be forced Autor: 17.09.12
  • 47. Syringing (Interpretation) ● Regurgitation through opposite punctum – obstruction in the common canaliculus or more distal structures ● Regurgitation via the same punctum indicates punctal obstruction ● Drainage via nose does not rule out physiological obstruction Autor: 17.09.12
  • 48. Diagnostic probing Hard stop Soft stop Autor: 17.09.12
  • 49. Irrigation / probing interpretation Autor: 17.09.12
  • 50. Radiological evaluation ● Dacryocystography ● Nuclear lacrimal scintigraphy ● CT ● MRI Autor: 17.09.12
  • 51. Dacryocystography ● Anatomical investigation ● Creates interior image of the entire lacrimal system ● Radio opaque water soluble dye is injected into the canaliculus ● Magnified images are created ● Digital subtraction is used Autor: 17.09.12
  • 52. Radiologic criteria of lacrimal pathology ● Regurgitation of radio-opaque fluid into the conjunctival sac ● Absence of fluid in the nose ● Fluctuation of lumen of lacrimal system ● Irregularity in contrast ● Deformation involving lacrimal sac Autor: 17.09.12
  • 53. Nuclear lacrimal scintigraphy ● Non invasive physiological test ● Utilizes radiotracer technitium-99M pertechnitate. ● Images can be captured using epiphora ● Drop of technetium-99m instilled into conjunctiva ● Recording is made using gamma camera ● 20 mins is the recording time Autor: 17.09.12
  • 54. CT/MRI Helpful in identifying adjacent areas and other mass lesions Autor: 17.09.12
  • 55. Secretory tests ● Schimer's test ● Rose bengal test Autor: 17.09.12
  • 56. schirmer's test ● 35x5 mm paper ● 5 mins duration ● 10-30 mm wetness normal ● Above 30mm epiphora ● 10mm dryness Autor: 17.09.12