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Thoraco laparoscopic Esophagectomy
Dr Pradeep Jain M.Ch
Director
GI Surgery
Fortis Hospital Shalimar Bagh
Minimally Invasive Esophagectomy
 Enthusiasm -- Technical complexity &
Frequency
Lap > open
0
5
10
15
20
25
Cholecystectomy Gatric Bypass Esophagectomy
MIE (concerns)
 Safety
Surgery time
Blood loss
Morbidity and Mortality
 Recovery
ICU and Hospital Stay
Pain
 Oncological out come
LN yield and Resection margins
Survival
 Cost
Meta analysis
Biere SS, Cuesta MA, van der Peet D, Minimally invasive
versus open esophagectomy for cancer: a systematic
review and meta-analysis. Minerva Chir. 2009
Apr;64(2):121-33.
Nagpal K,Ahmed K,Vats A,Yakoub D, James D,Ashrafian
H, Darzi A, Moorthy K,Athanasiou T. Is minimally invasive
surgery beneficial in the management of esophageal
cancer? A meta-analysis . Surg Endosc. 2010
Jul;24(7):1621-9.
Sgourakis G, Gockel I, Radtke A, Musholt TJ,Timm S, Rink
A,Tsiamis A, Karaliotas C, Lang H Minimally invasive
versus open esophagectomy: meta-analysis of
outcomes. ) Dig Dis Sci. 2010 Nov;55(11):3031-40
Randomised Trials
 Miguel A. Cuesta, Surya S.A.Y. Biere, Mark I. van Berge
Henegouwen,and Donald L. van der Peet
Randomised trial, Minimally Invasive Oesophagectomy versus open
oesophagectomy for patients with resectable oesophageal cancer.
J Thorac Dis. 2012 October; 4(5): 462–46
 Open versus laparoscopically-assisted oesophagectomy for cancer:
a multicentre randomised controlled phase III trial - the MIRO trial.
Briez N, Piessen G, Bonnetain F, Brigand C, Carrere N, Collet
D, Doddoli C, Flamein R, Mabrut JY, Meunier B, Msika S, Perniceni
T, Peschaud F, Prudhomme M,Triboulet JP, Mariette C.
BMC Center 2011 Jul 23;11:310
Our Experience
( retrospective 10 years )
Esophagectomy (89)
0
2
4
6
8
10
12
14
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
Open MIE
Etiology (MIE 47)
0
5
10
15
20
25
30
35
40
45
Malignancy Achlasia Cardia Binign Stricture
MIE
0
5
10
15
20
25
30
35
40
45
McKeown Ivor Lewis
Port Position
Port Position
Thoraco Laparoscopic Esophagectomy
Ivor Lewis Esophagectomy
Operative Time
0
100
200
300
400
500
600
700
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
MIE
OPEN
Blood Loss
0
200
400
600
800
1000
1200
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
MIE
OPEN
ICU Stay
0
2
4
6
8
10
12
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
MIE
OPEN
Hospital Stay
0
2
4
6
8
10
12
14
16
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
MIE
OPEN
Lymph NodeYield
0
5
10
15
20
25
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
MIE
OPEN
0
0.5
1
1.5
2
2.5
3
3.5
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
MIE
Open
Major complications
- bleeding requiring major transfusion
- major leak requiring interventions
- respiratory complications requiring ventilation
- Thoracic duct injury
- RLN injury
Mortality
 5/89 30 day mortality
 1/47 MIE (pneumonia with septic
shock)
 4/42 Traditional ( Gastric conduit leak,
Thoracic duct injury,Thoracic
anastomosis leak, Pneumonia with sever
sepsis )
Summary
 Minimally invasive technique very well
feasible
 Immediate outcome better in MIE
 Prone position with double lung
anesthesia has less respiratory
complications
 Oncological superiority is yet to be
validated in prospective randomised trials
ThankYou

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