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Cancer awarnes

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cancer education

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Cancer awarnes

  1. 1. The growing burden of cancer in India Dr.Biplabendu Talukdar MD(Immuno-Hematology) M.Phil (Regenerative Medicine) Assistant Director (Medical), SBTC,WB
  2. 2. Epidemiology and social context •1million new cases of cancer diagnosed each year in 1.2 billion population. •1.7 million by 2035 •600 000- 700 000 deaths in India were caused by cancer. •Male and female ratio
  3. 3. Social context •Tobacco and alcohol use •Infection •Diet. •Physical inactivity •Altered bio-rhythms
  4. 4. Tobacco And Alcohol: Deadly Combination •It is estimated that tobacco smoking and alcohol drinking combined account for approximately ¾ of all oral and pharyngeal cancers
  5. 5. Tobacco consumption •India is home to 10% of the worlds smokers •India has 120 million tobacco users ( GATS- 2009-2010 ) •Cigarette and bidi smoking causes about 5% of all deathes in women and 20% of all deaths in men aged 30-69 years.
  6. 6. PASSIVE SMOKING • WHO estimates passive smoking causes 600 000 deaths every year • One third of those killed are children ,who are often exposed to smoke at home
  7. 7. Relationship Between Cell Events and Lesion Appearance DNA AdductsSmoking Environmental Factors Virus Diet DNA Damage Oral Leukoplakia [White Lesions] Erythroplakia [Red Lesions] Premalignant Oral Carcinoma Malignant DNA Repair DNA Content Cell Growth Apoptosis
  8. 8. Cervical Cancer • is the second most common malignancy in women worldwide • it is the leading cause of cancer-related death for women in developing countries. • In the United States, cervical cancer is relatively uncommon. it continues to rise in many developing countries.
  9. 9. Causes of cervical cancer • What is breast cancer? re sEarly epidemiological data demonstrated a direct causal relationship between cervical cancer and sexual activity. • Major risk factors include: • sex at a young age, • multiple sexual partners, • promiscuous male partners, • history of sexually transmitted diseases. • the search for a potential sexually transmitted carcinogen had been unsuccessful until breakthroughs in molecular biology enabled scientists to detect viral genome in cervical cells • ome Causes and risks? • What are the Symptoms? • How about some Epidemiology? • What’s the deal with BRCA1 and BRCA2? • Are there Early Detection and Treatments? • Do I have a check list I can follow?
  10. 10. • the first symptom is abnormal vaginal bleeding, usually postcoital. • Vaginal discomfort, malodorous discharge, and dysuria are not uncommon. • abnormal Papanicolaou test result. • The tumor grows by extending upward to the endometrial cavity, downward to the vagina, and laterally to the pelvic wall. • It can invade the bladder and rectum directly
  11. 11. • Strong evidence now implicates human papillomaviruses (HPVs) as prime suspects. • HPV viral DNA has been detected in more than 90% of squamous intraepithelial lesions (SILs) and invasive cervical cancers compared to a consistently lower percentage in controls. • Both animal data and molecular biologic evidence confirm the malignant transformation potential of papilloma virus–induced lesions. • SILs are found predominantly in younger women, • while invasive cancers are detected more often in women aged 10- 15 years older, suggesting slow progression of cancer.
  12. 12. When you hear the term breast cancer, what does it mean to you?
  13. 13. THE GLOBAL BREAST CANCER CRISIS Somewhere in the world… • A case of breast cancer is diagnosed every 19 seconds • A woman dies from breast cancer every 60 seconds Over the next 25 years… • Another 42 million new cases are expected worldwide • Another 13 million people worldwide will die from breast cancer
  14. 14. What is Breast Cancer? Breast cancer is a disease where cells in the breast tissue divide and grow without normal controls.
  15. 15. 15 Many changes occur over a woman’s lifetime. Puberty Menstrual Cycle Pregnancy Post Menopause 10/7/15 Confidential & Proprietary Breast Structure & Anatomical Changes
  16. 16. Benign Breast Conditions • Benign = not cancerous • Fibrocystic changes • Common benign changes: - Hyperplasia - Cysts - Fibroadenomas Calcifications
  17. 17. Women Breast Self – Awareness Messages 1. Know your risk 2. Know what is normal for you 3. Get screened 4. Make healthy lifestyle choices
  18. 18. Key Message – Know Your Risk Talk to your mother’s and father’s families about your family health history • Talk to a doctor about your risk of breast cancer
  19. 19. Imaging Tests Breast Ultrasound Mammography Breast Magnetic Resonance Imaging
  20. 20. Key Message – Make Healthy Lifestyle Choices Maintain a healthy weight • Add exercise into your routine • Limit alcohol intake • Limit menopausal hormone use • Breastfeed, if you can
  21. 21. Thank you