Gel Technology Delivers Nutrients in Revolutionary New Way

Gel Technology — Gelceuticals™
For additional information: http://www.geldocs.com/ohm.php

Do people actually consume the nutrients that will improve their health? Everyone starts
with good intentions. A few pills here, a glass of juice there. But before long, pills get
bothersome and glass bottles are less than portable.

How many times have we asked ourselves, “Now, why didn‘t I think of that?” So often, a
very simple idea goes unnoticed as we continue doing things the same old way, year after
year. Nutritional supplements are no different. For most of the last century, nutritional
supplements—primarily available in pill and tablet form—have gained popularity. With
the availability of each new supplement, we have been left with the same alternative:
swallow one more pill.

What if we didn?t have to choke down another tablet? What if there was another option?
What if somebody decided to deliver nutrients in a different form?

Good news! There’s a fresh new way to consume nutritional supplements, a new
technology known as Gelceuticals™. This delivery mechanism isn’t just new, its better—
it will revolutionize the way we take nutritional supplements and substantially increase
the number of individuals who benefit from nutritional supplementation.

Through suspension gel technology, our daily nutrients can be taken anywhere, quickly
and easily. Think about it: no glasses, no super-sized pills, no waterlogged juices, no
ineffective sprays and creams—just pure, concentrated nutrients in an easy to take,
readily absorbed, taste bud-busting gel. Entirely original, the Gelceutical market
represents an untapped arena of wellness. And the landmark realization of the industry is
Agel™. Agel stands at the head of a supplement revolution—incredible convenience,
incredible flavor.

Why is gel technology so much better? Two very important factors influence the efficacy
of nutritional supplements: 1) the proper timing of ingestion, and 2) the bioavailability of
the nutrients. Because of these factors, gel technology represents a significant advance in
the method of delivery for vitamins, minerals and other important food supplements. Gel
suspension drastically facilitates ingestion of food supplements, increasing compliance

Gel Technology 1

with nutritional regimens that would otherwise go unheeded. It provides extreme
convenience and allows for optimal timing of ingestion, thus maximizing nutritional
efficacy. And, it optimizes the bioavailability of the nutrients that are suspended in gel
form in order to maximize their physiologic effects.

Gel Technology 2

Agel EXO
EXO is the proprietary exotic antioxidant formula in our initial product offerings.
Antioxidants are substances that help prevent cellular damage in our bodies. Our body
has its own process of repair, but with the stress of current life-styles and the increasing
amount of pollutants in the environment, we may need some extra help. Ideally, we can
get most of the antioxidants we need by eating fruits and vegetables, essentials of a
healthy diet. However, in today’s fast —paced world we sometimes replace fresh fruits
and vegetables with less than ideal choices. Therefore, enhancing our less than optimal
diet with an exceptional antioxidant supplement may be extremely beneficial.

EXO is a powerful blend of 14 different unique whole fruit purees and plant extracts
from around the world, each with its own unique properties. This distinctive formula
contains 14 potent botanicals that each when tested individually was found to have a very
high total antioxidant capacity. Now imagine the extraordinary benefit of EXO, a highly
concentrated gel, made up of not one but 14 of these antioxidant-rich fruits and plants. In
independent testing, EXO’s antioxidant capacity as determined by an oxygen radical
absorbance capacity (ORAC) rating was found to be quite extraordinary.

Optimum health requires adequate nutrition. Adequate nutrition involves balance,
moderation and variety. Scientific literature suggests that the intake of a varied selection
of antioxidants is much better than taking high doses of just one or two antioxidants.
Since EXO is a highly concentrated gel containing a variety of antioxidant–rich
botanicals, the multifaceted benefits of this formulation are truly unique.

Ingredients: Dark Grape, Cranberry, Bilberry, Aronia, Blueberry, Pomegranate, Aloe
Vera, Para Guava, Noni, Acerola, Wolfberry, Açai, Ashwaganda, and Rooibos

Agel EXO uses
Agel’s EXO™ gel will help you delay signs of age–related declines. Aging causes
natural declines in your mobility, coordination, memory, vision, skin, hair and health.
These signs of aging often lead to persistant health conditions. This exclusive
Gelceutical™ blend of 14 all–natural fruits helps you age gracefully — slowing down the
visible signs of aging.*

The Need

The NeedSigns of age-related declines originate with every breath of oxygen. Oxygen is
the major source of harmful free radicals. Ironic that life-giving oxygen also causes signs
of health declines with advancing years. Oxygen free radicals have an unstable, single
electron (versus stable, paired electrons) enabling them to chemically alter lipids,
proteins, carbohydrates and even DNA. An oxygen free radical “attacks” a biomolecule
by “stealing”s one electron, thereby changing the “good biomolecule” into a reactive free
radical, but restoring oxygen to a stable state. Continual creation of biological free
radicals damages cells and tissues – leading to the visual signs of aging.*

Agel EXO 1

Agel EXO
Aging is a 24/7 declining process resulting from alterations to our normal biochemistry
within every cell of the body — free radical aging. Free radical aging results in less–
responsive cells. The life-extension capabilities of the cell are weakened when sections of
DNA experience free radical damage. Changing in DNA coding alters the biosynthesis of
proteins and enzymes that maintain normal cell functions. This is why aging is such a
slow, continuous process.*

The Solution

Agel’s EXO gel formulated with 14 exotic all–natural fruits and fruit extracts, each
containing a wide–variety of antioxidants. EXO abounds with over 200 distinct
antioxidants to shield, quench and repair the broadest spectrum of biological proteins,
membrane lipids and nucleic DNA free–radicals. EXO is your greatest biological shield
against the signs of age–related declines.*

Agel’s EXO GelBenefits:

1. Combats signs of age–related decline*
2. Supports youthful vision & recognition*
3. Maintains normal joint mobility*
4. Helps control youthful coordination*
5. Boosts immune function activity*
6. Enhances feelings of youthful energy*
7. Supports healthy cholesterol levels already within the normal range*
8. Guards healthy urinary tract health*
9. Shields the body from harmful free–radicals*
10. Reversing age–related losses in short–term memory*

Agel’s EXO Features:
1. Patent pending Gelceutical™ enhanced-bioactive technology
2. Over 200 natural antioxidants
3. Antioxidant BioShield™ antioxidant and immune activity
4. Antioxidant Recharging™ system*

The Mechanism

EXO’s antioxidant spectrum slows down signs of age–related decline. Regular
consumption of EXO releases an active army of antioxidants in your bloodstream. EXO
antioxidants work in two ways to minimize signs of aging — through EXO’s Antioxidant
BioShield™ and through its exclusive Antioxidant Recharging?. EXO’s Antioxidant
BioShield technology guards against free radical damage to both water-soluble and fat–
soluble biomolecules. The Antioxidant BioShield is very protective due the variety of
natural antioxidants within EXO’s 14 exotic fruits, including: flavonoids,
proanthocyanins, anthocyanins, phenolic acids, polyphenols, carotenoids, vitamins, and
essential minerals. EXO?s Antioxidant BioShield™ minimizes free radical bioactivity

Agel EXO 2

Agel EXO
and repairs free radical damage to cellular DNA, lipids, proteins and enzymes. Agel’s
Antioxidant BioShield also places the immune system on “surveillance alert” via active
fruit polysaccharides against foreign invaders.*

Antioxidant Recharging™ is Agel’s exclusive formulation technology that regulates
antioxidant bioactivity. For example, in the process of repairing a free radical–damaged
biomolecule with the vitamin E antioxidant, vitamin E becomes “deactivated” as an
antioxidant. With Agel’s exclusive Antioxidant Recharging™ system, the deactivated
vitamin E is recharged by vitamin C. The resulting water–soluble, “deactivated” vitamin
C is readily eliminated from the body following the recharging process. Agel’s EXO
contains many examples of coordinated Antioxidant Recharging. EXO’s exclusive
Antioxidant BioShield™ and Antioxidant Recharging™ provides you the best
bioprotection against signs of aging — 24/7.*

The Ingredient

The exotic antioxidant-rich fruits in EXO represent the best berry and fruit sources from
around the globe. Blueberries from the lush Pacific Northwest of USA, Dark-skinned
grapes from Europe and North America, Cranberries from quiet waters of Northeastern
USA, Bilberries from rich lands of Northern Europe, Aronia chokeberry from forests of
Central Europe, Pomegranate from Persia and Mediterranea, Aloe vera gel from the arid
Mexican plains, Noni fruit from mineral-rich Polynesian shores, Para guava from South
America, Acerola cherry from Brazil , Wolfberries from China and Southeast Asia, Acai
berries from Amazon rainforests, Ashwaganda from depths of India, Rooibos herb extract
from Africa. These selected fruits are ranked highest in ORAC rating ? a rating of
antioxidant bioactivity.*

*These statements have not been evaluated by the Food and Drug Administration. This
product is not intended to diagnose, treat, cure or prevent any disease

Agel EXO
Açai

Açai (a-sigh-ee) (Euterpe oleracea) is considered to be one of the most nutritious fruits of
the Amazon rainforest. It contains Vitamin B1 (Thiamin), Vitamin B2 (Riboflavin),
Vitamin B3 (Niacin), Vitamin C, Vitamin E (tocopherol), iron, potassium, phosphorus
and calcium. It also contains the essential fatty acids Omega 6 and Omega 9 (these are
the healthy fatty acids), and many of the essential amino acids, with a protein profile
similar to an egg. And, that is just for starters. What makes AÁai unique is that is very
rich in anthocyanins, which are very potent antioxidants. In fact, this amazing fruit
contains 33 times more anthocyanins than the red wine grape.

Agel EXO 3

Agel EXO
Anthocyanins as a class of nutrients are important in their ability to help prevent
atherosclerosis (clogged arteries), and generalized cellular damage caused by free
radicals in the body. They are considered to be very helpful in the anti-inflammatory
process, and may even help to lower LDL cholesterol (the bad cholesterol). In addition,
they play an important role in neutralizing dangerous carcinogens.

Açai is an amazing fruit with many health benefits. But, what is truly amazing is that it is
only one of the14 different exotic fruits and herbs contained in Agel EXO, each of which
are loaded with health enhancing nutrients.

References

1: Lichtenthaler R, Rodrigues RB, Maia JG, Papagiannopoulos M, Fabricius H, Marx F.
Int J Food Sci Nutr. 2005 Feb;56(1):53-64.

2: Hassimotto NM, Genovese MI, Lajolo FM.
J Agric Food Chem. 2005 Apr 20;53(8):2928-35.

3: Del Pozo-Insfran D, Brenes CH, Talcott ST.
J Agric Food Chem. 2004 Mar 24;52(6):1539-45.

Acerola

J Acerola (Malpighia glabra) is a fruit resembling the bing cherry that is believed to
originate from the Yucatan peninsula in South America. Some of the largest plantings in
modern times are in Brazil. It is one of the richest known food sources of vitamin C, and
it is for this reason that this fruit has played an important role in South American herbal
medicine. In addition, it has carotene content comparable to that of carrots, and is also a
good supply of magnesium, and several of the B vitamins; niacin, pantothenic acid,
vitamin B1 (thiamine), and vitamin B2 (riboflavin).

Vitamin C is a nutrient that must be supplied in the diet. It has many biological functions,
including the formation and maintenance of collagen (the primary protein of skin and
connective tissues), healthy maintenance of the liver and adrenal glands, and it is a
powerful natural antihistamine. However, one of its most important roles is that of an
antioxidant and its ability to help the body fight physiological stress. Our environment is
filled with external stresses and pollutants that put our bodies under extraordinary
pressure to maintain health. We are much more prone to infection and disease in our
metropolitan environments and the intake of extra vitamin C can serve as an excellent
adjunct to healthy living.

Some of the common ailments for which vitamin C is being taken in our modern society
include: allergies, atherosclerosis (clogged arteries), bronchitis, cancer prevention, colds
and flu, glaucoma, and skin wrinkles.

Agel EXO 4

Agel EXO
Acerola is loaded with many important nutrients, and it is an important component of
Agel EXO. It contributes synergistically with the other 13 exotic fruits and herbs to
create a supplement with exceptional health-enhancing properties.

References

1: Hanamura T, Hagiwara T, Kawagishi H.
Biosci Biotechnol Biochem. 2005 Feb;69(2):280-6.

2: Johnson PD.
World Rev Nutr Diet. 2003;91:67-75. Review.

3: Visentainer JV, Vieira OA, Matsushita M, de Souza NE.
Arch Latinoam Nutr. 1998 Sep;48(3):256-9.

Aloe Vera
References

1: Su CK, Mehta V, Ravikumar L, Shah R, Pinto H, Halpern J, Koong A, Goffinet D, Le
QT.
Int J Radiat Oncol Biol Phys. 2004 Sep 1;60(1):171-7.

2: Langmead L, Feakins RM, Goldthorpe S, Holt H, Tsironi E, De Silva A, Jewell DP,
Rampton DS.
Aliment Pharmacol Ther. 2004 Apr 1;19(7):739-47.

3: Langmead L, Makins RJ, Rampton DS.
Aliment Pharmacol Ther. 2004 Mar 1;19(5):521-7.

Aronia

Aronia (Aronia melanocarpa) is a shrub that is native to the northeastern part of the
United States. It produces clusters of small dark purple berries that are also known as
“black chokeberries.” It has close botanical ties to the bilberry and the cranberry in that is
contains high levels of anthocyanins and flavonoids, both of which are very potent
antioxidants. It has been reported that the aronia berry contains over five times greater
levels of these compounds than the cranberry.

Antioxidants are so important in our modern day–to–day living as we are constantly
being bombarded with oxidative stresses. Antioxidants are substances that prevent
cellular damage by acting as scavengers and neutralize free radicals by donating electrons
to these electron–deprived compounds. The body has its own mechanisms for dealing
with free radicals, but they can be inadequate, particularly with the added stress of current
life–styles and the increasing amount of pollutants in the environment. For optimal
health, it is therefore necessary to complement these processes with antioxidants from our

Agel EXO 5

Agel EXO
diet. Fortunately, antioxidants are abundantly present in fresh fruits and vegetables,
which are an essential part of a healthy diet. However, as we substitute the intake of fresh
fruits and vegetables in our diets with other “empty” calories, the need to take food
supplements rich in antioxidants becomes increasingly important.

The Aronia berry is just one of 14 different exotic fruits and herbs contained in Agel
EXO that is loaded with these important antioxidants.

References

1: Pilaczynska-Szczesniak L, Skarpanska-Steinborn A, Deskur E, Basta P,
Horoszkiewicz-Hassan M.
Int J Sport Nutr Exerc Metab. 2005 Feb;15(1):48-58.

2: Zhao C, Giusti MM, Malik M, Moyer MP, Magnuson BA.
J Agric Food Chem. 2004 Oct 6;52(20):6122-8.

3: Zheng W, Wang SY.
J Agric Food Chem. 2003 Jan 15;51(2):502-9.

Ashwaganda

Ashwaganda (Withania somnifera), also known as “Indian ginseng”, is a small evergreen
that comes from the drier parts of western India, northern Africa, the Mediterranean, and
the Middle East. It is related to the tomato plant of North America, and all of its parts,
including its roots, oval leaves, showy yellow flowers, and red, raisin–sized fruits are
used medicinally in various cultures. It is considered a major herb of the Ayurvedic
system of health and healing which has been practiced in India for more than 2000 years.

Ashwaganda is an adaptogen, which is a substance that non–specifically enhances the
body’s ability to resist disease, revitalize and increase performance. In India, this herb is
celebrated as an adaptogen that will do the following: boost strength, increase stamina
and relieve fatigue, strengthen the immune system, speed recovery from chronic illness,
soothe and calm without producing drowsiness, clarify the mind and improve memory,
and slow the aging process. It is one of the most frequently used remedies in India.
Because Ashwaganda has a sedative effect on the central nervous system, it is also used
in Chinese medicine for cases of nervousness, insomnia, and rheumatic pains.

It is clear that ashwaganda contains biologically active compounds that are responsible
for the healing effects of this herb. However, these compounds have not yet been clearly
identified. Nonetheless, this herb is time tested in the eastern cultures and has proven to
have many important healing effects. Laboratory studies continue to be done in an effort
to more clearly understand this beneficial herb.

Agel EXO 6

Agel EXO
Ashwaganda, by itself is an amazing herb with many health benefits. But, in Agel EXO,
it represents only a part of the wonderful ensemble of 14 exotic fruits and herbs from
around the world.

The Aronia berry is just one of 14 different exotic fruits and herbs contained in Agel
EXO that is loaded with these important antioxidants.

References

1: Owais M, Sharad KS, Shehbaz A, Saleemuddin M.
Phytomedicine. 2005 Mar;12(3):229-35.

2: Agarwal R, Diwanay S, Patki P, Patwardhan B.
J Ethnopharmacol. 1999 Oct;67(1):27-35.

3: Mishra LC, Singh BB, Dagenais S.
Altern Med Rev. 2000 Aug;5(4):334-46. Review.

Bilberry

As we continue to explore the wonderful health benefits of the 14 different exotic fruits
and herbs in Agel EXO, it becomes increasingly more exciting to realize how truly
unique it is. Today, let’s explore the bilberry.

Bilberry (Vaccinium myrtillus) is a shrubby perennial bush that is commonly found in
Europe, western Asia and in North America. The bilberry bears edible fruits that are
related to the American blueberry, the cranberry and also the huckleberry. In fact, it is
commonly called the “European blueberry.”

For centuries, European herbalists have been using the Bilberry to treat a myriad of
health related ailments, including urinary tract infections, diarrhea, night blindness, and
many others. Of particular interest is the prolific use of the bilberry during World War II
when British Royal Air Force pilots noticed a significant improvement in their night
vision capabilities after consuming bilberry preserves prior to going out on bombing
missions. Subsequent research has shown that bilberries are very powerful antioxidants,
and it is in part because of this valuable property that they have such wonderful medicinal
capabilities. In modern times, the bilberry has become a very popular nutritional
supplement and it has been found helpful in treating various vision related problems,
including poor night vision, cataracts and macular degeneration.

Researchers who have looked into the bilberry have identified the anthocyanins which are
found abundantly in the bilberry as the substance responsible for most of the medicinal
properties of this exotic fruit. Anthocyanins are very potent antioxidants and they appear
to play a very important role in maintaining the integrity of our blood vessels, both large
and very small. They appear to help prevent atherosclerosis (clogging of the arteries) in
many of our vital organs. It is for this reason that they may be so beneficial in preventing

Agel EXO 7

Agel EXO
heart disease, in helping with visual ailments, and in preventing some of the debilitating
consequences of chronic diseases such as diabetes.

The bilberry is just one of 14 different exotic fruits and herbs contained in Agel EXO,
each with its own repertoire of health enhancing properties.

References

1: Faria A, Oliveira J, Neves P, Gameiro P, Santos-Buelga C, de Freitas V, Mateus N.
J Agric Food Chem. 2005 Aug 24;53(17):6896-6902.

2: Ramirez MR, Izquierdo I, Raseira MD, Zuanazzi JA, Barros D, Henriques AT.
Pharmacol Res. 2005 Aug 9;

3: Kramer JH.
Surv Ophthalmol. 2004 Nov-Dec;49(6):618;

Blueberry

The Blueberry (Vaccinium angustifolium) is very closely related to the Bilberry of
northern Europe and to the Cranberry of North America. It is one of the few fruits native
to North America. It has been used by the native Americans for centuries as a tasty food
source and as a medicinal aid. Like it’s relatives, the blueberry is a rich source of the
phenolic antioxidant called anthocyanin, as well as potassium, calcium, vitamins A, C,
and E, folic acid, and fiber. It is reported by researchers at the USDA Human Nutrition
Center (HNRCA) that blueberries have higher antioxidant capacity than 40 other fresh
fruits and vegetables.

Recent animal research indicates that blueberries may be beneficial in slowing the
process of age-related mental decline, possibly a result of the high antioxidant capacity of
the anthocyanins that are so prevalent in this fruit. Also a result of this important
compound, blueberries may help reduce the build up LDL (“bad” cholesterol) and thus
help prevent heart disease and strokes. Also like its close relative, the bilberry, the
blueberry may play a role in improving eyesight and reducing eye strain.

Just like many of the Vaccinium berries (bilberry, cranberry) the blueberry contains
another biologically active substance called resveratrol. This compound has been found
to suppress tumor cell proliferation and induce apoptosis (programmed tumor cell death)
in selected cancer cell lines. Resveratrol also has anti-inflammatory and antioxidant
properties as well.

Although the blueberry is not a cure–all, it does contain biologically important substances
may help us to live better and healthier lives. It is an important component of Agel EXO,
and it contributes synergistically with the other 13 exotic fruits and herbs to create a
supplement with exceptional health–enhancing properties.

Agel EXO 8

Agel EXO
References

1: Wang Y, Chang CF, Chou J, Chen HL, Deng X, Harvey BK, Cadet JL, Bickford
PC.
Exp Neurol. 2005 May;193(1):75-84.

2: Joseph JA, Shukitt-Hale B, Casadesus G.
Am J Clin Nutr. 2005 Jan;81(1 Suppl):313S-316S. Review.

3: Kay CD, Holub BJ.
Br J Nutr. 2002 Oct;88(4):389-98.

Cranberry Extract

The North American Cranberry (Vaccinium macrocarpon) has a long and distinguished
history. Not only has it been a food source, but has been used in ceremonies and for
medicinal purposes. Cranberries are packed with nutrients and have been extensively
researched. Cranberries have long been the focus of interest for their beneficial effects in
preventing urinary tract infections. Cranberries contain proanthocyanidin compounds
which prevent bacteria from attaching to the uroepithelial cells in the urinary tract.

Cranberries not only contain antioxidants but have anti-cancer and anti-inflammatory
properties as well. Cranberries contain powerful phenolic antioxidants like anthocyanins,
specifically it is the quercetin glycosides that provide cranberries with their free radical
scavenging and enzyme inhibiting actions. The phenol antioxidants have also been shown
to increase HDL (the “good” cholesterol) and reduce the oxidation of LDL (the “bad”
cholesterol) potentially decreasing the risk of atherosclerosis. Resveratrol is an anti-
cancer compound that is found naturally in cranberries. Resveratrol has been found to
suppress tumor cell proliferation and induce apoptosis (programmed tumor cell death) in
selected cancer cell lines. Resveratrol also has anti-inflammatory and anti-oxidative
properties as well.

Cranberries are paced with nutrients and are an excellent source of antioxidants. Agel
EXO, users can take advantage of the powerful antioxidant properties along with the
benefits of 13 other exotic fruits and herbs from around the world.

Reference

1: Duthie SJ, Jenkinson AM, Crozier A, Mullen W, Pirie L, Kyle J, Yap LS, Christen P,
Duthie GG.
Eur J Nutr. 2005 Jul 20;

2: Gettman MT, Ogan K, Brinkley LJ, Adams-Huet B, Pak CY, Pearle MS.
J Urol. 2005 Aug;174(2):590-4; quiz 801.

Agel EXO 9

Agel EXO
3: Crews WD Jr, Harrison DW, Griffin ML, Addison K, Yount AM, Giovenco MA,
Hazell J.
J Altern Complement Med. 2005 Apr;11(2):305-9.

Dark Grape
References

1: Puiggros F, Llopiz N, Ardevol A, Blade C, Arola L, Salvado MJ.
J Agric Food Chem. 2005 Jul 27;53(15):6080-6.

2: Jung KJ, Wallig MA, Singletary KW.
Cancer Lett. 2005 May 5;

3: Chou EJ, Keevil JG, Aeschlimann S, Wiebe DA, Folts JD, Stein JH.
Am J Cardiol. 2001 Sep 1;88(5):553-5.

Noni

Noni (Morinda citrifola) is an evergreen plant that is native to Malaysia, Australia, and
Polynesia. There is reference to its use as a healing botanical in ancient Sanskrit
Ayurvedic (traditional medicine in India) medical texts dating back thousands of years. It
has been used to treat many different health disorders over the same period in multiple
cultures, and it is only recently that its biologically active components have been
identified and its healing properties have been explained.

In the Noni fruit, scientists have identified significant quanities of a precursor
(proxeronine) to the pharmacologically active substance called xeronine. The proxeronine
is ingested as part of the fruit and is converted to xeronine in the digestive tract and is
subsequently absorbed into the body. Xeronine is believed to play a significant role in the
proper synthesis and function of proteins that are crucial to the health of each our body’s
cells. Generally speaking, this molecule has an influence on multiple organ systems
within our bodies and therefore can affect the proper function of multiple cellular
processes that all contribute to our overall health. As a result, the list of ailments that
have been treated by the Noni fruit for thousands of years is long and comprehensive. For
this reason, the noni fruit is considered by some cultures to be a “cure all” for most health
related complaints. Certainly, in our sophisticated, technologically advanced society, it is
difficult to make that claim. However, it is clear based on millennia of experience that the
noni fruit has some important healing properties.

Noni, by itself is an amazing fruit with many health benefits. But, in Agel EXO, it
represents only a part of the wonderful ensemble of 14 exotic fruits and herbs from
around the world.

Agel EXO 10

Agel EXO
References

1: Langford J, Doughty A, Wang M, Clayton L, Babich M.
J Altern Complement Med. 2004 Oct;10(5):737-9.

2: McClatchey W.
Integr Cancer Ther. 2002 Jun;1(2):110-20; discussion 120. Review.

3: Hirazumi A, Furusawa E.
Phytother Res. 1999 Aug;13(5):380-7.

Pomegranate

The Pomegranate (Punica granatum) has an extensive history as a medicinal fruit. The
first historical evidence of pomegranate trees being planted dates back as far as 3000 BC.
It has legendary medicinal properties that have made it the subject of numerous myths,
epics and works of art from renowned artists including Raphael, Cezanne, Homer, and
even Shakespeare. In multiple regions of the world, this wonderful fruit has been revered
as a symbol of health, fertility and of rebirth. It is native to the Middle Eastern region of
the world, but through the ages has become a popular agricultural product all over the
globe.

The pomegranate fruit is a valuable source of potassium, vitamin C and of polyphenols. It
is likely a result of the excellent antioxidant capacity of the polyphenols that the
pomegranate has been given such wide acclaim through the ages. As modern day science
has demonstrated time and time again, antioxidants are valuable adjuncts to healthy
living. They are attributed to the reduction and prevention of coronary artery disease
(clogging of the heart vessels), and even the prevention of some of the biological
processes that cause cancer and aging.

The pomegranate has a great history as a health-enhancing fruit. And yet, it is but one of
the 14 wonderful exotic fruits and herbs that make Agel EXO an outstanding antioxidant
gel.

References

1: Fuhrman B, Volkova N, Aviram M.
J Nutr Biochem. 2005 Sep;16(9):570-6.

2: Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D.
J Nutr Biochem. 2005 Jun;16(6):360-7.

3: Esmaillzadeh A, Tahbaz F, Gaieni I, Alavi-Majd H, Azadbakht L.
J Med Food. 2004 Fall;7(3):305-8.

Agel EXO 11

Agel EXO
Rooibos

Last week, we highlighted the excellent health benefits of Agel EXO. It is a very
effective blend of 14 highly concentrated exotic fruit juices, purees and plant extracts
coming from countries across the globe. Individually they have excellent antioxidant
capacities, and when combined, the result is an extraordinary antioxidant supplement.
This week, we want to explore one of the individual herbs that make up this formulation.
Let’s talk about Rooibos.

Rooibos is a shrub that is indigenous to the mountains of South Africa’s Western Cape.
More than 300 years ago, the inhabitants of those mountains started collecting Rooibos
leaves and used them for making tea. During the past 3 centuries, Rooibos tea has been
used in various cultures for many different medicinal purposes. It contains many natural
antioxidants, and unlike black tea, it does not contain caffeine and has a very low tannin
content. Technically speaking, Rooibos is loaded with polyphenols (flavinoids and
phenolic acids). It is, in large part, the high content of these antioxidants that give it the
qualities that make it a very useful herb in the treatment of many different ailments. In
addition to helping counteract the oxidative stresses of contemporary life, many South
African herbalists use it to help curb anxiety and even help with insomnia as it
presumably affects the metabolism of one of the brain messengers (acetylcholine). In
other cultures, it is used to treat allergies, as it seems to interfere with histamine. In
addition, it is used to treat infant colic, as it tends to have anti-spasmodic properties in the
intestines.

Roobios is a wonderful herb in its own right. Now, with Agel EXO, we can enjoy its
unique antioxidant properties in combination with 13 other fruits and herbs from all
around the world.

References

1: Ulicna O, Vancova O, Bozek P, Carsky J, Sebekova K, Boor P, Nakano M, Greksak
M.
Physiol Res. 2005 May 24;

2: Ulicna O, Greksak M, Vancova O, Zlatos L, Galbavy S, Bozek P, Nakano M.
Physiol Res. 2003;52(4):461-6.

3: Kunishiro K, Tai A, Yamamoto I.
Biosci Biotechnol Biochem. 2001 Oct;65(10):2137-45.

Wolfberry
References

1: Zhang M, Chen H, Huang J, Li Z, Zhu C, Zhang S.
Life Sci. 2005 Mar 18;76(18):2115-24.

Agel EXO 12

Agel EXO
2: Zhao H, Alexeev A, Chang E, Greenburg G, Bojanowski K.
Phytomedicine. 2005 Jan;12(1-2):131-7.

3: Gan L, Hua Zhang S, Liang Yang X, Bi Xu H.
Int Immunopharmacol. 2004 Apr;4(4):563-9.

Wolfberry References
1: Wu SJ, Ng LT, Lin CC.
Phytother Res. 2004 Dec;18(12):1008-12.

2: Hai-Yang G, Ping S, Li JI, Chang-Hong X, Fu T.
J Exp Ther Oncol. 2004 Oct;4(3):181-7.

3: Cheng CY, Chung WY, Szeto YT, Benzie IF.
Br J Nutr. 2005 Jan;93(1):123-30.

4: Du G, Liu L, Fang J.
J Huazhong Univ Sci Technolog Med Sci. 2004;24(5):518-20, 527.

5: Ha KT, Yoon SJ, Choi DY, Kim DW, Kim JK, Kim CH.
J Ethnopharmacol. 2005 Jan 15;96(3):529-35.

6: Luo Q, Cai Y, Yan J, Sun M, Corke H.
Life Sci. 2004 Nov 26;76(2):137-49.

7: Gan L, Zhang SH, Liu Q, Xu HB.
At Eur J Pharmacol. 2003 Jun 27;471(3):217-22.

8: Luo Q, Yan J, Zhang S.
Wei Sheng Yan Jiu. 2000 Mar 30;29(2):115-7. Chinese.

9: Luo Q, Yan J, Zhang S.
Zhong Yao Cai. 1999 May;22(5):246-9. Chinese.

10: Li G, Yang J, Ren B, Wang Z.
Wei Sheng Yan Jiu. 2002 Feb;31(1):30-1. Chinese.

Rooibos References
1: Lee EJ, Jang HD.
Biofactors. 2004;21(1-4):285-92.

Agel EXO 13

Agel EXO
2: Kucharska J, Ulicna O, Gvozdjakova A, Sumbalova Z, Vancova O, Bozek P, Nakano
M, Greksak M.
Physiol Res. 2004;53(5):515-21.

3: Bramati L, Aquilano F, Pietta P.
J Agric Food Chem. 2003 Dec 3;51(25):7472-4.

4: Bramati L, Minoggio M, Gardana C, Simonetti P, Mauri P, Pietta P.
J Agric Food Chem. 2002 Sep 25;50(20):5513-9.

5: Simon M, Horovska L, Greksak M, Dusinsky R, Nakano M.
Gen Physiol Biophys. 2000 Dec;19(4):365-71.

6: Standley L, Winterton P, Marnewick JL, Gelderblom WC, Joubert E, Britz TJ.
J Agric Food Chem. 2001 Jan;49(1):114-7.

7: Nakano M, Itoh Y, Mizuno T, Nakashima H.

8: Lamosova D, Jurani M, Greksak M, Nakano M, Vanekova M.
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1997 Jan;116(1):39-45.

9: Inanami O, Asanuma T, Inukai N, Jin T, Shimokawa S, Kasai N, Nakano M, Sato F,
Kuwabara M.
Neurosci Lett. 1995 Aug 18;196(1-2):85-8.

10: Komatsu K, Kator K, Mitsuda Y, Mine M, Okumura Y.
Cancer Lett. 1994 Feb 28;77(1):33-8.

Pomegranate References
1: Azadzoi KM, Schulman RN, Aviram M, Siroky MB.
J Urol. 2005 Jul;174(1):386-93.

2: de Nigris F, Williams-Ignarro S, Lerman LO, Crimi E, Botti C, Mansueto G,
D'Armiento FP, De Rosa G, Sica V, Ignarro LJ, Napoli C.
Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4896-901.

3: Sudheesh S, Vijayalakshmi NR.
Fitoterapia. 2005 Mar;76(2):181-6.

4: Lansky EP, Harrison G, Froom P, Jiang WG.
Invest New Drugs. 2005 Mar;23(2):121-2.

Agel EXO 14

Agel EXO
5: Mehta R, Lansky EP.
Eur J Cancer Prev. 2004 Aug;13(4):345-8.

6: Aviram M, Rosenblat M, Gaitini D, Nitecki S, Hoffman A, Dornfeld L, Volkova N,
Presser D, Attias J, Liker H, Hayek T.
Clin Nutr. 2004 Jun;23(3):423-33.

7: Toi M, Bando H, Ramachandran C, Melnick SJ, Imai A, Fife RS, Carr RE, Oikawa T,
Lansky EP.
Angiogenesis. 2003;6(2):121-8.

8: Aviram M, Dornfeld L, Kaplan M, Coleman R, Gaitini D, Nitecki S, Hofman A,
Rosenblat M, Volkova N, Presser D, Attias J, Hayek T, Fuhrman B. f
Drugs Exp Clin Res. 2002;28(2-3):49-62. Review.

9: Noda Y, Kaneyuki T, Mori A, Packer L.

10: Aviram M, Dornfeld L.
Atherosclerosis. 2001 Sep;158(1):195-8.

Noni References

2: McClatchey W.


Noni References Page


5: McClatchey W.


7: Su BN, Pawlus AD, Jung HA, Keller WJ, McLaughlin JL, Kinghorn AD.
J Nat Prod. 2005 Apr;68(4):592-5.

Agel EXO 15

Agel EXO
8: Kamiya K, Tanaka Y, Endang H, Umar M, Satake T.
J Agric Food Chem. 2004 Sep 22;52(19):5843-8.

9: Furusawa E, Hirazumi A, Story S, Jensen J.

10: Wang MY, West BJ, Jensen CJ, Nowicki D, Su C, Palu AK, Anderson G
Acta Pharmacol Sin. 2002 Dec;23(12):1127-41. Review.

11: Salleh MN, Runnie I, Roach PD, Mohamed S, Abeywardena MY.
J Agric Food Chem. 2002 Jun 19;50(13):3693-7.

12: Liu G, Bode A, Ma WY, Sang S, Ho CT, Dong Z.
Cancer Res. 2001 Aug 1;61(15):5749-56.

13: Hirazumi A, Furusawa E, Chou SC, Hokama Y.
Proc West Pharmacol Soc. 1996;39:7-9.

Dark Grape References
1: Chou EJ, Keevil JG, Aeschlimann S, Wiebe DA, Folts JD, Stein JH.
Am J Cardiol. 2001 Sep 1;88(5):553-5.

2: Peng N, Clark JT, Prasain J, Kim H, White CR, Wyss JM.
Am J Physiol Regul Integr Comp Physiol. 2005 Sep;289(3):R771-5.

3: Lee JH, Johnson JV, Talcott ST.

4: Balu M, Sangeetha P, Murali G, Panneerselvam C.
Int J Dev Neurosci. 2005 Oct;23(6):501-7.

5: Balu M, Sangeetha P, Haripriya D, Panneerselvam C.
Neurosci Lett. 2005 Aug 5;383(3):295-300.

6: Park YK, Kim JS, Kang MH.
Biofactors. 2004;22(1-4):145-7.

7: Bitsch R, Netzel M, Frank T, Strass G, Bitsch I.
J Biomed Biotechnol. 2004;2004(5):293-298.

8: Meng X, Maliakal P, Lu H, Lee MJ, Yang CS.
J Agric Food Chem. 2004 Feb 25;52(4):935-42.

Agel EXO 16

Agel EXO
9: Park YK, Park E, Kim JS, Kang MH.
Mutat Res. 2003 Aug 28;529(1-2):77-86. Erratum in: Mutat Res. 2004 Feb 26;546(1-
2):103.

10: Freedman JE, Parker C 3rd, Li L, Perlman JA, Frei B, Ivanov V, Deak LR, Iafrati
MD, Folts JD.
Circulation. 2001 Jun 12;103(23):2792-8.

Cranberry References
1: Duthie SJ, Jenkinson AM, Crozier A, Mullen W, Pirie L, Kyle J, Yap LS, Christen P,
Duthie GG.
Eur J Nutr. 2005 Jul 20;

2: Gettman MT, Ogan K, Brinkley LJ, Adams-Huet B, Pak CY, Pearle MS.
J Urol. 2005 Aug;174(2):590-4; quiz 801.

3: Crews WD Jr, Harrison DW, Griffin ML, Addison K, Yount AM, Giovenco MA,
Hazell J.
J Altern Complement Med. 2005 Apr;11(2):305-9.

4: Howell AB, Reed JD, Krueger CG, Winterbottom R, Cunningham DG, Leahy M.
Phytochemistry. 2005 Jul 28;

5: Ruel G, Pomerleau S, Couture P, Lamarche B, Couillard C.
Metabolism. 2005 Jul;54(7):856-61.

6: Chu YF, Liu RH.
Life Sci. 2005 Aug 26;77(15):1892-901.

7: Vattem DA, Ghaedian R, Shetty K.
Asia Pac J Clin Nutr. 2005;14(2):120-30.

8: Berger RE.
J Urol. 2005 Jun;173(6):1988.

9: Puupponen-Pimia R, Nohynek L, Hartmann-Schmidlin S, Kahkonen M, Heinonen M,
Maatta-Riihinen K, Oksman-Caldentey KM.
J Appl Microbiol. 2005;98(4):991-1000.

10: Rhee KY, Charles M.
Clin Infect Dis. 2004 Sep 15;39(6):877.

Blueberry References

Agel EXO 17

Agel EXO
1: Wang Y, Chang CF, Chou J, Chen HL, Deng X, Harvey BK, Cadet JL, Bickford PC.
Exp Neurol. 2005 May;193(1):75-84.

2: Joseph JA, Shukitt-Hale B, Casadesus G.
Am J Clin Nutr. 2005 Jan;81(1 Suppl):313S-316S. Review.

3: Kay CD, Holub BJ.
Br J Nutr. 2002 Oct;88(4):389-98.

Pharmacol Res. 2005 Aug 9; [

5: Galli RL, Bielinski DF, Szprengiel A, Shukitt-Hale B, Joseph JA.
Neurobiol Aging. 2005 Apr 30;

6: Lichtenthaler R, Marx F.

7: Taruscio TG, Barney DL, Exon J.
J Agric Food Chem. 2004 May 19;52(10):3169-76.

8: Goyarzu P, Malin DH, Lau FC, Taglialatela G, Moon WD, Jennings R, Moy E, Moy
D, Lippold S, Shukitt-Hale B, Joseph JA.
Nutr Neurosci. 2004 Apr;7(2):75-83.

9: Nakajima JI, Tanaka I, Seo S, Yamazaki M, Saito K.
J Biomed Biotechnol. 2004;2004(5):241-247.

10: Joseph JA, Denisova NA, Arendash G, Gordon M, Diamond D, Shukitt-Hale B,
Morgan D.
Nutr Neurosci. 2003 Jun;6(3):153-62.

Billberry References
1: Faria A, Oliveira J, Neves P, Gameiro P, Santos-Buelga C, de Freitas V, Mateus N.
J Agric Food Chem. 2005 Aug 24;53(17):6896-6902.

Pharmacol Res. 2005 Aug 9;

3: Kramer JH.
Surv Ophthalmol. 2004 Nov-Dec;49(6):618;

4: Cicero AF, Derosa G, Gaddi A.
Acta Diabetol. 2004 Sep;41(3):91-8. Review.

Agel EXO 18

Agel EXO
5: Ichiyanagi T, Hatano Y, Matsuo S, Konishi T.
Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1312-5.

6: Blodi BA.
Insight. 2004 Jan-Mar;29(1):15-6; quiz 17-8. Review.

7: Ichiyanagi T, Kashiwada Y, Ikeshiro Y, Hatano Y, Shida Y, Horie M, Matsugo S,
Konishi T.
Chem Pharm Bull (Tokyo). 2004 Feb;52(2):226-9.

8: Canter PH, Ernst E.
Surv Ophthalmol. 2004 Jan-Feb;49(1):38-50. Review.

9: Erlund I, Marniemi J, Hakala P, Alfthan G, Meririnne E, Aro A.
Eur J Clin Nutr. 2003 Jan;57(1):37-42.

10: Muth ER, Laurent JM, Jasper P.
Altern Med Rev. 2000 Apr;5(2):164-73.

Ashwagandha References
1: Owais M, Sharad KS, Shehbaz A, Saleemuddin M.
Phytomedicine. 2005 Mar;12(3):229-35.

2: Agarwal R, Diwanay S, Patki P, Patwardhan B.
J Ethnopharmacol. 1999 Oct;67(1):27-35.

3: Mishra LC, Singh BB, Dagenais S.
Altern Med Rev. 2000 Aug;5(4):334-46. Review.

4: Rani G, Kaur K, Wadhwa R, Kaul SC, Nagpal A.
Food Chem Toxicol. 2005 Jan;43(1):95-8.

5: Kaur K, Rani G, Widodo N, Nagpal A, Taira K, Kaul SC, Wadhwa R.
Food Chem Toxicol. 2004 Dec;42(12):2015-20.

6: Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S.
Phytomedicine. 2000 Dec;7(6):463-9.

7: Bucci LR.
Am J Clin Nutr. 2000 Aug;72(2 Suppl):624S-36S. Review.

8: Panda S, Kar A.
Indian J Physiol Pharmacol. 1997 Oct;41(4):424-6.

Agel EXO 19

Agel EXO
9: Ziauddin M, Phansalkar N, Patki P, Diwanay S, Patwardhan B.
J Ethnopharmacol. 1996 Feb;50(2):69-76.

10: Malhotra CL, Mehta VL, Das PK, Dhalla NS.
Indian J Physiol Pharmacol. 1965 Jul;9(3):127-36.

Aronia References
1: Pilaczynska-Szczesniak L, Skarpanska-Steinborn A, Deskur E, Basta P,
Horoszkiewicz-Hassan M.
Int J Sport Nutr Exerc Metab. 2005 Feb;15(1):48-58.

2: Zhao C, Giusti MM, Malik M, Moyer MP, Magnuson BA.
J Agric Food Chem. 2004 Oct 6;52(20):6122-8.

3: Zheng W, Wang SY.

4: Valcheva-Kuzmanova S, Borisova P, Galunska B, Krasnaliev I, Belcheva A.
Exp Toxicol Pathol. 2004 Dec;56(3):195-201.

5: Wu X, Gu L, Prior RL, McKay S.
U Agric Food Chem. 2004 Dec 29;52(26):7846-56.

6: Malik M, Zhao C, Schoene N, Guisti MM, Moyer MP, Magnuson BA.
Nutr Cancer. 2003;46(2):186-96.

7: Kowalczyk E, Kopff A, Niedworok J, Kopff M, Jankowski A.
Kardiol Pol. 2002 Oct;57(10):332-6. English, Polish.

8: Simeonov SB, Botushanov NP, Karahanian EB, Pavlova MB, Husianitis HK, Troev
DM.
Folia Med (Plovdiv). 2002;44(3):20-3.

9: Kahkonen MP, Hopia AI, Heinonen M.
J Agric Food Chem. 2001 Aug;49(8):4076-82.

10: Borissova P, Valcheva S, Belcheva A.
Acta Physiol Pharmacol Bulg. 1994;20(1):25-30.

Agel EXO 20

Agel EXO
Aloe Vera References
1: Su CK, Mehta V, Ravikumar L, Shah R, Pinto H, Halpern J, Koong A, Goffinet D, Le
QT.
Int J Radiat Oncol Biol Phys. 2004 Sep 1;60(1):171-7.

2: Langmead L, Feakins RM, Goldthorpe S, Holt H, Tsironi E, De Silva A, Jewell DP,
Rampton DS.
Aliment Pharmacol Ther. 2004 Apr 1;19(7):739-47.

3: Langmead L, Makins RJ, Rampton DS.
Aliment Pharmacol Ther. 2004 Mar 1;19(5):521-7.

4: Yagi A, Takeo S.
Yakugaku Zasshi. 2003 Jul;123(7):517-32. Review. Japanese.

5: Ikeno Y, Hubbard GB, Lee S, Yu BP, Herlihy JT.

6: Vogler BK, Ernst E.
Br J Gen Pract. 1999 Oct;49(447):823-8. Review.

7: Chithra P, Sajithlal GB, Chandrakasan G.
J Ethnopharmacol. 1998 Jan;59(3):179-86.

8: Kim HS, Lee BM.
Carcinogenesis. 1997 Apr;18(4):771-6.

9: Ajabnoor MA.
J Ethnopharmacol. 1990 Feb;28(2):215-20.

10: Davis RH, Leitner MG, Russo JM, Byrne ME.
Wound healing. Oral and topical activity of Aloe vera.
J Am Podiatr Med Assoc. 1989 Nov;79(11):559-62.

11: Ghannam N, Kingston M, Al-Meshaal IA, Tariq M, Parman NS, Woodhouse N.
Horm Res. 1986;24(4):288-94.

Acerola References
1: Hanamura T, Hagiwara T, Kawagishi H.

Agel EXO 21

Agel EXO
2: Johnson PD.
World Rev Nutr Diet. 2003;91:67-75. Review.

3: Visentainer JV, Vieira OA, Matsushita M, de Souza NE.
Arch Latinoam Nutr. 1998 Sep;48(3):256-9.


5: Hanamura T, Hagiwara T, Kawagishi H. M

6: Motohashi N, Wakabayashi H, Kurihara T, Fukushima H, Yamada T, Kawase
M,Sohara Y, Tani S, Shirataki Y, Sakagami H, Satoh K, Nakashima H, Molnar A,
Spengler G, Gyemant N, Ugocsai K, Molnar J.
Phytother Res. 2004 Mar;18(3):212-23.

7: Wakabayashi H, Fukushima H, Yamada T, Kawase M, Shirataki Y, Satoh K, Tobe T,
Hashimoto K, Kurihara T, Motohashi N, Sakagami H.
Anticancer Res. 2003 Jul-Aug;23(4):3237-41.

8: Johnson PD. World Rev Nutr Diet. 2003;91:67-75. Review.

9: De Assis SA, Martins AB, Guaglianoni DG, De Faria Oliveira OM.

10: Nagamine I, Akiyama T, Kainuma M, Kumagai H, Satoh H, Yamada K, Yano T,
Sakurai H. J Nutr Sci Vitaminol (Tokyo). 2002 Feb;48(1):69-72.

11: Hwang J, Hodis HN, Sevanian A.
J Agric Food Chem. 2001 Jan;49(1):308-14.

12: BOWERS EF, KUBIK MM.
Br J Clin Pract. 1965 Mar;19:141-7.

Açai References
1: Lichtenthaler R, Rodrigues RB, Maia JG, Papagiannopoulos M, Fabricius H, Marx F.
Int J Food Sci Nutr. 2005 Feb;56(1):53-64.


3: Del Pozo-Insfran D, Brenes CH, Talcott ST.
J Agric Food Chem. 2004 Mar 24;52(6):1539-45.

Agel EXO 22

Agel EXO
4: Murrieta RSS, Dufour DL, Siqueira AD; Human Ecol. 1999, 27: 455-475.

5: Muniz-Miret N, Vamos R, Hiraoka M, Montagnini F, Medelsohn RO;
Forest Ecol. Manage. 1996, 87: 163-173.

6: Silva S; Fruit in Brazil; Dados Internacionais de Catalogacao na Publicao; Sao Paulo,
Brazil; 1996: 14-17.

Agel EXO 23

Agel UMI
Agel's newest product, UMI, offers a vast array of health benefits that have only really
been appreciated by coastal communities with abundant access to brown seaweed. The
active ingredient in UMI is Fucoidan, which is a component of brown seaweed. For
centuries, brown seaweed has been considered a natural source of healthy food and
nutrition. But, it has only been recently that further research has identified Fucoidan, a
sulfated polysaccharide, as the true source of the health and wellness benefits of this
oceanic wonder. Fucoidan has piqued the interest of many scientists and researchers as
one of the ocean's greatest treasures. However, as scientists have continued to explore
this complex molecule, more and more of its health benefits have been identified.

Fucoidan is like a closely guarded secret kept by those coastal societies that have enjoyed
the wonderful health benefits of the Fucoidan polysaccharide for centuries.

With Agel UMI, the secret is out. This new gelceutical that delivers Fucoidan in a good
tasting gel brings the amazing health benefits of this potent polysaccharide to the rest of
the world where seaweed is not a common part of the every day diet. It is encouraging
that now everybody can enjoy healthier living as a result of Agel UMI.

Agel UMI Benefits
In many parts of the world, seaweed is not a regular part of the daily diet. In fact, there
are many people who would not even consider eating seaweed. However, with Agel
UMI, the exceptional health benefits of this oceanic treasure are now available to the
masses. So, what is it about the brown seaweed that is so extraordinary? Through
extensive research, scientists have identified a complex sulfated polysaccharide, called
fucoidan as the active ingredient. Its primary makeup consists of an essential sugar called
fucose along with other elements such as xylose, mannose, and galactose, and glucose.
Studies consistently show that fucoidan possesses a wide range of properties beneficial to
maintaining optimal health.

One of the primary ways in which Fucoidan provides a vast array of health benefits is its
ability to interact with, and modulate the immune system. Several studies have identified
many of the immune modulating effects of Fucoidan.1 2 The ability of a substance to
modulate the immune system is an extremely useful property. Modulation is a term used
to describe the process of reducing the extremes of cellular activity – either stimulation or
inhibition. Immune modulating substances have the ability to increase immune function
when it is depressed, such as in conditions like chronic fatigue, and then to reduce it
when it is over-stimulated, such as in auto-immune diseases like lupus or rheumatoid
arthritis.

Most immune modulating agents work by improving inter-cellular communication. One
way cells interact and communicate is by presenting glycoproteins on their surface.
Glycoproteins are complex information-rich macromolecules composed of a protein core
to which is bound arrays of linked saccharides or sugars (polysaccharides). The structures
of the saccharides vary and therefore relay different codes for different messages. For

Agel UMI 1

Agel UMI
example, one message might tell a cell to secrete a specific cellular product, and another
message might tell a cell when to divide. Other cells have corresponding glycoprotein
receptor molecules, which can then read these messages and respond accordingly. Thus,
our bodies are involved in a very sophisticated and harmonious intercellular
communication all the time.

The immune system depends heavily on this kind of communication to co-ordinate
cellular defense, apoptosis, cell attack and repair processes. When any of the range of
saccharides required to build competent glycoproteins (and thereby convey an accurate
message) are missing, the quality of that communication is compromised. It has been
shown that dietary supply of certain saccharides improves the integrity of glycoprotein
production. Fucoidans provide an abundant supply of Fucose, one of the necessary
saccharides, and smaller amounts of several other required sugars. This is likely to be one
mechanism by which the fucoidans exert their immunomodulatory effect.

Now, with this understanding of glycoprotiens, and intercellular communication, let’s
specifically identify the ways in which Fucoidan has been shown to be of significant
benefit for health and wellness.

References

1: Antibacterial and immunomodulating activity of fucoidan, Zapopozhets TS,
Besednova NN, Loenko IuN. Antibiot Khimioter. 1995 Feb;40(2):9-13.

2: Immunostimulating and anticoagulating activity of fucoidan from brown algae Fucus
evanescens of Okhotskoe sea. Kuznetsova TA, Zaporozhets TS, Besednova NN, et al.
Antibiot Khimioter. 2003;48(4):11-3.

Regenerate Cells and Increase Life Span

Much of the research that has been done on fucoidan has been focused on its ability to
regenerate cells. Studies have shown that fucoidan helps support mobilization of stem
cells that enable the body to replace dead cells thereby enabling tissue and organ
regeneration.3 In addition, fucoidan helps slow symptoms of the aging process. In study
after study, fucoidan has shown itself to be beneficial in the fight for a longer, healthier
life.

References

3: Sulfated Glycans Induce Rapid Hematopoietic Progenitor Cells Mobilization:
Evidence for Selectin-dependent and Independent Mechanisms. Frenette PS, Weiss L.
Blood, 2000 Oct 1 96(7):2460-8

Agel UMI 2

Agel UMI
Support the Circulatory System & Health Functions

Fucoidan has also been shown to help maintain healthy blood flow and cardiac
functions—thereby supporting the circulatory system.4 5 6 7 Increased blood flow helps all
of our organs work more efficiently and helps us to feel better and healthier.8 Efficient
functioning of our vital organs can help us prolong the effects of “wear and tear” of the
normal aging process. Additionally, one study suggested that fucoidan helps to slow the
absorption rate of glucose, or sugar, into the blood stream. A slower absorption rate leads
to a more regulated blood sugar level.

References

4: Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia. McCaffrey TA,
Falcone DJ, Borth W, Brayton CF, Weksler BB. Biochem Biophys Res Commun. 1992
Apr 30;184(2):773-81.

5: Fibrinolytic and anticoagulant activities of highly sulfated Fucoidan. Soeda S,
Sakaguchi S, Shimeno H, Nagamatsu A. Biochem Pharmacol. 1992 Apr 15;43(8):1853-8.

6: Potential Antioxidant Capacity of Sulfated Polysasccharides From the Edible Brown
Seaweed Fucus Vesiculosus. Ruperez P. Ahrazern O. Leal JA Agrie Food Chem. 2002
Feb 13;50(4):840-5

7: Anticoagulant properties of a Fucoidan fraction. Colliec S, Fischer AM, Tapon-
Bretaudiere J, Boisson C, Durrand P, Jozefonvicz J. Thromb Res. 1991 Oct 15;64(2):143-
54.

8: Intravascular granulocyte aggregates caused by the selectin-binding carbohydrate
fucoidan in pig kidneys. Dittrich S, Lippek F, Gratopp A, Grosse-Siestrup C, Lange PE,
Buhrer C. Clin Exp Pharmacol Physiol. 2002 Oct; 29 (10): 909-14

Maintain Healthy Cholesterol Levels

The process of cholesterol formation is in the liver. Our bodies produce a “good”
cholesterol (HDL) and a “bad” cholesterol (LDL). Optimum health is achieved when we
can maintain lower levels of the LDL, and sufficient levels of the HDL. There is some
evidence to suggest that fucoidan can help us to maintain healthy levels of cholesterol by
influencing the metabolic activity in the liver where fatty acids are processed.9 In
addition, because fucoidan is a dietary fiber, it absorbs cholesterols contained in foods
allowing them to be discharged from the body. This suppresses cholesterol elevations
related to dietary intake of foods high in cholesterol.

References

9: Hepatic fatty acid oxidation enzyme activities are stimulated in rats fed the brown
seaweed. Murata, M. et al. Journal of Nutrition, 1999 Jan:29(1):146-51.

Agel UMI 3

Agel UMI
Help Support Healthy Joint Functions

For many of us in the United States and throughout the world, healthy joints and cartilage
are daily concerns. Arthritis and joint pain can be a bothersome and sometimes
debilitating. Among its many properties, fucoidan has been hailed as a natural answer to
joint health. Fucoidan supports proper joint functions and cartilage health by modulating
some of our body’s inflammatory and immune processes.10 11 12

References

10: Effects of the anti-inflammatory compounds castanospermine, mannose-6-phosphate
and fucoidan on allograft rejection and elicited peritoneal exudates. Bartlett MR, Warren
HS, Cowden WB Parish CR Immunol Cell Biol. 1994 Oct; 72(5):367-74

11: Immunomodulating activity of arabinogalactan and Fucoidan in vitro. Choi EM, Kim
AJ, Kim YO, Hwang JK. J Med Food. 2005 Winter;8(4):446-53.

12: Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of
connective tissue proteolysis. Senni K, Gueniche F, Foucault-Bertaud A, Igondjo-Tchen
S, Fioretti F, Colliec-Jouault S, Durand P, Guezennec J, Godeau G, Letourneur D. Arch
Biochem Biophys. 2006 Jan 1;445(1):56-64.

Assist in Inducing the Elimination of Harmful Cells

Fucoidan may also prove helpful in eliminating harmful cells, including those that are
related to some cancers. This is accomplished through a process called apoptosis.
Apoptosis is technical term for the process of a cell “bursting” and therefore dying.
Sulphated polysaccharides like fucoidan have been shown to assist in inducing apoptosis,
which is a natural process where living organisms eliminate harmful cells and render the
genetic blueprint (DNA) of harmful cells useless.13 14 15 16 Additionally, some research
suggests that fucoidan may have an effect on cancer growth by suppressing the
generation of new blood vessels around cancer cells, cutting off their nutrient supply.

References

13: Antitumor activity and immune response of Mekabu fucoidan extracted from
Sporophyll of Undaria pinnatifida. Maruvama H, Tamauchi H, Hashimoto M, Nakano T.
In Vivo. 2003 May-Jun;17(3):245-9

14: Antitumor activity and immunological properties of marine algal polysaccharides,
especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae. Itoh H. Noda
H, Amano H, Zhuang C, MizunoT, Ito H Anticancer Res. 1993 Nov-Dec;13(6A):2045-52

15: Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of
human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell

Agel UMI 4

Agel UMI
leukemia cells. Haneji K, Matsuda T, Tomita M, Kawakami H, Ohshiro K, Uchihara JN,
Masuda M, Takasu N, Tanaka Y, Ohta T, Mori N. Nutr Cancer. 2005;52(2):189-201.

16: Antitumor and antiproliferative effects of fucan extracted from ascophyllum nodosum
against a non-small-cell bronchopulmonary carcinoma line. Riou D, Colliec-Jouault S,
Pnczon du Sel D, Bosch S, Siavoshian S, Le Bert V, Tomasoni C, Sinquin C, Durand P,
Roussakis C. Anticancer Res. 1996 May-Jun;16(3A):1213-8.

Help Maintain a Strong Immune System

Fucoidan supports the immune system in a number of different ways. Some research
suggests that it may cause an increase in the number of circulating mature white blood
cells in the body, which are an integral part of the body’s natural immune system.17 The
findings from other studies suggest that fucoidan supports the immune system by
improving phagocytosis and activating other important immune responses. These
processes act together to destroy bacteria, viruses and other foreign particles by multiple
blood “scavenger” cells.18 19 20 21

References


18: Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum
thunbergii). Zhuang C. et al. Biosci Biotechnol Biochem, 1995 Apr:59(4):563-7.

19: Antibacterial and immunomodulating activity of Fucoidan. Zapopozhets TS,
Besednova NN, Loenko IuN. Anitbiot Khimoioter. 1995 Feb;40(2):9-13.

20: Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV
agent in vitro. Baba M, Nakajima M, Schols D, Pauwels R, Balzarini J, De Clercq E.
Antiviral Res. 1988 Sep;9(6):335-43.

21: Anitviral properties of Fucoidan fractions from Leathesia difformis. Feldman SC,
Reynaldi S, Stortz CA, Cerezo AS, Damont EB. Phytomedicine. 1999 Nov;6(5):335-40.

Promotes Optimal Gastrointestinal Health

The number of people suffering from gastric diseases is rapidly increasing around the
world as more and more people are consuming foods with more fat content and less
dietary fiber. Once in the stomach, fucoidan attaches to the stomach lining where it has a
protective effect. In addition, it stimulates the stomach lining to regulate the
inflammatory process and also to “self-repair” damaged tissue. Fucoidan, because of its
immune promoting and inflammation modulating activity, is a tremendous aid in
maintaining proper gastrointestinal function and health.22

Agel UMI 5

Agel UMI
References

22: Fucoidan derived from Cladosiphon okamuranus Tokida ameliorates murine chronic
colitis through the down-regulation of interleukin-6 production on colonic epithelial cells,
Matsumoto S.,Nagaoka M, Hara T. Kimura-Takagi I, Mistsuvama K. Clinical and
Experimental Immunology. June 2004, vol. 136, no.3 pp. 432-439(8)

Increase Energy & Support Respiratory Functions

Fucoidan supports immunological abilities by assisting the body in the production of
interferon-Y and interleukin-12 while supporting normal respiratory functions.23

References

23: The Polysaccharide Fucoidan Inhibits the Antibiotic-induced Inflammatory Cascade
in Experimental Pneumococcal Meningitis, Granert C. Raud J, Lindquist L, Clinical and
Diagnostic Laboratory Immunology, May 1998, 5(3): 322-4

Detoxify the Body and Help Rid The Body of Free Radicals

The deleterious effect of free radicals on our bodies is well documented. The beneficial
effect of antioxidants in helping to neutralize the oxidative stresses placed upon our
organs and metabolic processes is also very clear. Fucoidan has a long list of health and
wellness properties, not the least of which is that it also is a rich supply of antioxidants.24

References

24: Potential Antioxidant Capacity of Sulphated Polysaccharides From the Edible Brown
Seaweed Fucus Vesiculosus. Ruperez P, Ahrazem O, Leal JA. Agric Food Chem. 2002
Feb 13; 50(4):840-5

Promotes Kidney Health

The kidneys serve as the “waste disposal system” for our bodies. Therefore, the proper
function of our kidneys is vital to our overall health and wellbeing. There are numerous
studies in the literature to suggest that fucoidan may play a significant roll in maintaining
optimal kidney function.25 26 27 28

References

25: Intravascular granulocyte aggregates caused by the selectin-¬binding carbohydrate
fucoidan in pig kidneys. Dittrich S, Lippek F, Gratopp A. Grosse-Siestrup C, Lange PE.
Buhrer C, Clin Exp Pharmacol Physiol. 2002 Oct 29(10):909-14

Agel UMI 6

Agel UMI
26: Protective effects of inhibiting both blood and vascular selectins after stroke and
reperfusion. Ruehl ML, Orozco JA, Stoker MB, McDonagh PF, Coull BM, Ritter LS.
Neurol Res. 2002 Apr;24(3):226-32.

27: Effects of Fucoidan on chronic renal failure in rats. Zhang Q, Li Z, Xu Z, Niu X,
Zhang H. Planta Med. 2003 Jun;69(6):537-41.

28: Fucoidan inhibits the development of proteinuria in active Heymann nephritis. Zhang
Q, Li N, Zhao T, Qi H, Xu Z, Li Z. Phytother Res. 2005 Jan;19(1):50-3

Supports Vibrant Health & Vitality

Fucoidan supports the body against “complement activation” believed to play an adverse
role in chronic degenerative symptoms like atherosclerosis, myocardial infarction,
alzheimer’s disease and other conditions associated with aging.29

The literature is plentiful supporting the fact that fucoidan is a valuable resource for
maintaining optimal health. The brown algae harvested from the earth’s ocean are truly
one of the most valuable gifts of the great deep. And Agel has harnessed this power into a
single gelceutical—UMI.

References

29: Effects of C-reactive protein and pentosan polysulphate on human complement
activation. Klegeris A. Singh EA. McGerr PL Immunology 2002 Jul;106(3):381-8

UMI References
1: Antibacterial and immunomodulating activity of fucoidan, Zapopozhets TS,
Besednova NN, Loenko IuN. Antibiot Khimioter. 1995 Feb;40(2):9-13.

2: Immunostimulating and anticoagulating activity of fucoidan from brown algae Fucus
evanescens of Okhotskoe sea. Kuznetsova TA, Zaporozhets TS, Besednova NN, et al.
Antibiot Khimioter. 2003;48(4):11-3.

3: Sulfated Glycans Induce Rapid Hematopoietic Progenitor Cells Mobilization:
Evidence for Selectin-dependent and Independent Mechanisms. Frenette PS, Weiss L.
Blood, 2000 Oct 1 96(7):2460-8

4: Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia. McCaffrey TA,
Falcone DJ, Borth W, Brayton CF, Weksler BB. Biochem Biophys Res Commun. 1992
Apr 30;184(2):773-81.

5: Fibrinolytic and anticoagulant activities of highly sulfated Fucoidan. Soeda S,
Sakaguchi S, Shimeno H, Nagamatsu A. Biochem Pharmacol. 1992 Apr 15;43(8):1853-8.

Agel UMI 7

Agel UMI
6: Potential Antioxidant Capacity of Sulfated Polysasccharides From the Edible Brown
Seaweed Fucus Vesiculosus. Ruperez P. Ahrazern O. Leal JA Agrie Food Chem. 2002
Feb 13;50(4):840-5

7: Anticoagulant properties of a Fucoidan fraction. Colliec S, Fischer AM, Tapon-
Bretaudiere J, Boisson C, Durrand P, Jozefonvicz J. Thromb Res. 1991 Oct 15;64(2):143-
54.

8: Intravascular granulocyte aggregates caused by the selectin-binding carbohydrate
fucoidan in pig kidneys. Dittrich S, Lippek F, Gratopp A, Grosse-Siestrup C, Lange PE,
Buhrer C. Clin Exp Pharmacol Physiol. 2002 Oct; 29 (10): 909-14

9: Hepatic fatty acid oxidation enzyme activities are stimulated in rats fed the brown
seaweed. Murata, M. et al. Journal of Nutrition, 1999 Jan:29(1):146-51.

10: Effects of the anti-inflammatory compounds castanospermine, mannose-6-phosphate
and fucoidan on allograft rejection and elicited peritoneal exudates. Bartlett MR, Warren
HS, Cowden WB Parish CR Immunol Cell Biol. 1994 Oct; 72(5):367-74

11: Immunomodulating activity of arabinogalactan and Fucoidan in vitro. Choi EM, Kim
AJ, Kim YO, Hwang JK. J Med Food. 2005 Winter;8(4):446-53.

12: Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of
connective tissue proteolysis. Senni K, Gueniche F, Foucault-Bertaud A, Igondjo-Tchen
S, Fioretti F, Colliec-Jouault S, Durand P, Guezennec J, Godeau G, Letourneur D. Arch
Biochem Biophys. 2006 Jan 1;445(1):56-64.

13: Antitumor activity and immune response of Mekabu fucoidan extracted from
Sporophyll of Undaria pinnatifida. Maruvama H, Tamauchi H, Hashimoto M, Nakano T.
In Vivo. 2003 May-Jun;17(3):245-9


15: Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of
human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell
leukemia cells. Haneji K, Matsuda T, Tomita M, Kawakami H, Ohshiro K, Uchihara JN,
Masuda M, Takasu N, Tanaka Y, Ohta T, Mori N. Nutr Cancer. 2005;52(2):189-201.

16: Antitumor and antiproliferative effects of fucan extracted from ascophyllum nodosum
against a non-small-cell bronchopulmonary carcinoma line. Riou D, Colliec-Jouault S,
Pnczon du Sel D, Bosch S, Siavoshian S, Le Bert V, Tomasoni C, Sinquin C, Durand P,
Roussakis C. Anticancer Res. 1996 May-Jun;16(3A):1213-8.

Agel UMI 8

Agel UMI

18: Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum
thunbergii). Zhuang C. et al. Biosci Biotechnol Biochem, 1995 Apr:59(4):563-7.

19: Antibacterial and immunomodulating activity of Fucoidan. Zapopozhets TS,
Besednova NN, Loenko IuN. Anitbiot Khimoioter. 1995 Feb;40(2):9-13.

20: Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV
agent in vitro. Baba M, Nakajima M, Schols D, Pauwels R, Balzarini J, De Clercq E.
Antiviral Res. 1988 Sep;9(6):335-43.

21: Anitviral properties of Fucoidan fractions from Leathesia difformis. Feldman SC,
Reynaldi S, Stortz CA, Cerezo AS, Damont EB. Phytomedicine. 1999 Nov;6(5):335-40.

22: Fucoidan derived from Cladosiphon okamuranus Tokida ameliorates murine chronic
colitis through the down-regulation of interleukin-6 production on colonic epithelial cells,
Matsumoto S.,Nagaoka M, Hara T. Kimura-Takagi I, Mistsuvama K. Clinical and
Experimental Immunology. June 2004, vol. 136, no.3 pp. 432-439(8)

23: The Polysaccharide Fucoidan Inhibits the Antibiotic-induced Inflammatory Cascade
in Experimental Pneumococcal Meningitis, Granert C. Raud J, Lindquist L, Clinical and
Diagnostic Laboratory Immunology, May 1998, 5(3): 322-4

24: Potential Antioxidant Capacity of Sulphated Polysaccharides From the Edible Brown
Seaweed Fucus Vesiculosus. Ruperez P, Ahrazem O, Leal JA. Agric Food Chem. 2002
Feb 13; 50(4):840-5

25: Intravascular granulocyte aggregates caused by the selectin-¬binding carbohydrate
fucoidan in pig kidneys. Dittrich S, Lippek F, Gratopp A. Grosse-Siestrup C, Lange PE.
Buhrer C, Clin Exp Pharmacol Physiol. 2002 Oct 29(10):909-14

26: Protective effects of inhibiting both blood and vascular selectins after stroke and
reperfusion. Ruehl ML, Orozco JA, Stoker MB, McDonagh PF, Coull BM, Ritter LS.
Neurol Res. 2002 Apr;24(3):226-32.

27: Effects of Fucoidan on chronic renal failure in rats. Zhang Q, Li Z, Xu Z, Niu X,
Zhang H. Planta Med. 2003 Jun;69(6):537-41.

28: Fucoidan inhibits the development of proteinuria in active Heymann nephritis. Zhang
Q, Li N, Zhao T, Qi H, Xu Z, Li Z. Phytother Res. 2005 Jan;19(1):50-3

29: Effects of C-reactive protein and pentosan polysulphate on human complement
activation. Klegeris A. Singh EA. McGerr PL Immunology 2002 Jul;106(3):381-8

Agel UMI 9

Agel MIN
Vitamins and Minerals are essential tools in everyday human physiology. They function
as coenzymes and cofactors that are involved in almost all biochemical processes in the
body. In essence, vitamins and minerals are crucial to healthy living.

Before the days of “fast food” and “empty” calories, these vitamins and minerals were
found naturally in our food. However, in modern days, as the average diet consists mostly
of processed, manufactured food, there is overwhelming scientific evidence to support
the intake of dietary supplements that are rich in vitamins and minerals [1-5].

Agel MIN is a proprietary formulation of vitamins and minerals that provides 100% of
the RDI (Recommended Daily Intake) of almost all the essential vitamins and as much as
50% of the RDI of most of the essential minerals. More importantly, the bioavailability of
these vitamins and minerals is enhanced due to the revolutionary gel technology
employed in the MIN formulation. The vitamins and minerals are either dissolved or
suspended in the gel, resulting in immediate availability for absorption by the digestive
tract. In addition, the minerals used in the formulation of MIN are Albion™ Chelates.
Albion Laboratories, Inc. is the world’s major producer of patented amino acid chelated
minerals. Albion’s patented chelation processes bind minerals to amino acids, markedly
increasing their bioavailability.

There are some who advocate using mega doses of various vitamins, presuming that if
some is good, more is better. However, there is growing scientific evidence that too much
of a good thing can be harmful [6-7]. Therefore, Agel’s formulation for a moderate dose
of readily available vitamins and minerals is ideal.

MIN: StaMINa and Ageless Zest
Agel™ MIN is the Gelceutical™ designed to nourish your stamina and deliver zesty
health. MIN contains required daily levels of 12 essential vitamins and high levels of 11
essential minerals. MIN helps you get more energy from your food, and then stores these
energy reserves to provide stamina. In addition, MIN’s essential vitamins and minerals
sustain of over 5000 vital biofunctions to deliver vigor, drive, well-being and ageless
zest.

MIN Health Benefits
StaMINa™

Stamina is defined as the complete physical and cognitive energy required for an active
lifestyle. Unfortunately, many people lack stamina. They seem to “walk into a wall”.
MIN contains 12 essential vitamins and 11 essential minerals to maintain your stamina.
Increased stamina is obtained from MIN by providing essential nutrients that 1) generate
stamina energy from food and 2) create an efficient biochemistry throughout the body.

Agel MIN 1

Agel MIN
StaMINa Generation

Vitamins and minerals are closely involved in the processes of converting food into
energy. They are cofactors of enzymes that efficiently generate biochemical energy from
carbohydrates, fats and proteins in the diet. Increased efficiency equals increased energy.

StaMINa = Energy Reserves

Trillions of biochemical reactions take place every second within the body to maintain
vigor, wellness and gusto. Every biochemical reaction requires energy. Essential vitamins
and minerals work with biocatalytic enzymes that minimize the energy necessary for
each biochemical reaction. Multiply trillions of reactions over thousands of seconds each
day equal substantial energy reserves. These energy reserves provide stamina. Therefore,
vitamins and minerals save energy — helping the body biochemistry to run efficiently.
Stamina is the result of efficiency.

Ageless Zest™

Regardless of age, the body should feel zest. Zest is a drive to live, feeling vim & vigor,
and a state of good health regardless of one’s chronological age. Ageless Zest is a
composite of thousands and thousands of properly functioning biochemical reactions
within the body. These biochemical reactions allow over 5000 functions within the body
to maintain overall health, vigor, vim and vitality. Ageless Zest may be associated with
vision, joints, bones, teeth, hair, smell, taste, hearing, touch, immune functions, heart,
lungs, gastrointestinal, nerves, brain, muscles, tendons, cartilage, hormones,
reproduction, pregnancy, respiration, coordination, etc. Falling levels of any one or more
essential vitamins or minerals can create instabilities with some of the over 5000
functions – resulting in loss of zest, drive, spirit and vivacity. MIN’s essential vitamins
and minerals help maintain necessary micronutrient levels to ensure stability of over 5000
biofunctions. Ageless Zest is A-Z health.

Who and When

MIN is recommended for healthy adults, teenagers, children and athletes. Consume MIN
at the same time every day. Consume one Agel MIN packet a day. Endurance athletes
may consume a second MIN packet for stamina.

Precautions

Pregnant or nursing women should consult with their physician concerning the MIN
formula.

Those who need MIN’s StaMINa and Ageless Zest
• Unable to finish tasks
• Tired of life

Agel MIN 2

Agel MIN
• Without drive to work
• Lacking vim and vigor
• Why don’t I feel enthusiastic?
• Always feel tired
• No get-up-and-go
• Frequently feel sick
• Wish I had more sick-days
• Loss of spirit to innovate
• Poor physical condition
• I’m feeling my age
• Less enthusiasm
• Feeling older every day
• Life is too complicated
• Wishing to be more successful
• My kids are always sick
• Where to people get all that stamina?
• My drive to work slows down by afternoon
• There is no “dash” to my step
• Feeling “over-the-hill”

*This statement has not been evaluated by the Food and Drug Administration. This
product is not intended to diagnose, treat, cure or prevent any disease.

Agel MIN - Essential Vitamin Ingredients
Vitamin A (Retinol, Retinal & Retinoic acid)

an essential fat-soluble vitamin. Vitamin A’s precursor is beta-carotene, a member of the
antioxidant carotenoid family, is transported by retinol-binding protein to its destinations.
Vitamin A is essential for proper vision, protein synthesis, cell differentiation,
reproduction and growth. Vitamin A is found in dark leafy greens (spinach & broccoli)
and yellow/orange vegetables & fruits (carrots, cantaloupe, winter squash, pumpkin,
mango, - not corn or banana). Early signs of Vitamin A deficiency include anemia, bone
weakness, joint pain, cracked teeth and frequent tooth decay.

Vitamin D (Calciferol)

an essential fat-soluble vitamin. Vitamin D can be synthesized by the body (with
adequate exposure to sunlight) in connection with previtamin D3. The active form of
Vitamin D (calcitriol) is a messenger that signals calcium-availability for bone growth.
Vitamin D, A, C & K, along with minerals calcium, phosphorus & magnesium are
essential for bone growth. Vitamin D is found in fortified milk, fortified margarine and
butter; as well as synthesized by UV sunlight exposure. Early signs of Vitamin D
deficiency include bone weakness (rickets) and bone brittleness (osteoporosis).

Agel MIN 3

Agel MIN
Vitamin E (Tocopherol)

an essential fat-soluble vitamin. Vitamin E is a powerful fat-soluble antioxidant that
protects cell wall fluidity and nutrient transport. Vitamin E antioxidant is recharged by
Vitamin C. Vitamin E is found in vegetable oils, olive oil, leafy green vegetables, whole
grains, nuts and seeds. Early signs of Vitamin E deficiency include fatigue, leg cramps,
blurred vision, nausea, anemia, loss in muscle coordination and impaired speech.

Vitamin C (Ascorbic acid)

an essential water-soluble vitamin. Vitamin C is a powerful antioxidant against free
radicals and is helpful for neurotransmitters synthesis (helping with coordination).
Vitamin C helps you receive energy by efficiently metabolizing amino acids (from
protein). Vitamin C is found in citrus, berries, fruits, & green vegetables. Early signs of
deficiency are usually in elderly, alcoholics, and infants. Vitamin C may guard against
colds and help your immune system.

Vitamin B1 (Thiamin)

an essential water-soluble B-vitamin. Thiamin is an enzyme cofactor (with TPP) for
efficient conversion of protein, carbohydrate and fat into energy. Thiamin is important for
proper functioning of nerve membranes. It is needed for the metabolism of many sugars.
Thiamin is found in whole grains, meats, greens & beans. Early signs of deficiency are
depression, muscle weakness (after only 10 days), apathy, confusion, irritability and rapid
degeneration of nervous system activity.

Vitamin B2 (Riboflavin)

an essential water-soluble B-vitamin. Riboflavin is an enzyme cofactor (with FAD and
FMN) for many energy metabolism reactions involving dietary proteins, carbohydrates
and fats. Riboflavin is found in dark, green, leafy vegetables & dairy products. Early
signs of deficiency are that minor injuries do not heal because new cells cannot replace
old cells, confusion, greasy skin, inflammation of the eyes, lips, or tongue.

Vitamin B3 (Niacin)

an essential water-soluble B-vitamin. Niacin is an enzyme cofactor (with NAD and
NADP) for rapid metabolism of protein, carbohydrate and fat to energy in every cell.
Niacin is found in dairy products, meats & whole grains. Early signs of B3 deficiency are
fatigue, decreased appetite, indigestion that can lead to diarrhea, dermatitis, dementia and
death.

Agel MIN 4

Agel MIN
Vitamin B5 (Pantothenic acid)

an essential water-soluble B-vitamin. Pantothenic acid is an enzyme cofactor (with CoA)
for energy metabolism from all food sources. Pantothenic acid is found in meats,
mushrooms, broccoli and whole grains. Early signs of deficiency include fatigue,
vomiting, nausea, stomach cramps, insomnia, depression, irritability and apathy.

Vitamin B6 (Pyridoxine)

an essential water-soluble B-vitamin. Pyridoxine is an enzyme cofactor (with PLP &
PMP) converting amino acids & fatty acids into energy. Some pyridoxine can be stored
in muscle tissue. Vitamin B6 influences immune system activity and cognitive
performance. Vitamin B6 is found in bananas, potatoes, chicken, fish, and meats. Early
signs of B6 deficiency include anemia, depression, confusion, fatigue, headaches, nerve
damage and dermatitis.

Vitamin B12 (Cobalamin)

an essential water-soluble B-vitamin. Vitamin B12 activates folate activity and is
activated by folate. Vitamin B12 helps DNA synthesis for new cells, protects nerve cells,
and promotes normal growth & bone cell activity. B12 found in meats & dairy products.
Early signs of B12 deficiency include fatigue, hypersensitivity of skin, anemia, sore
tongue & degeneration of nerves.

Folate

an essential water-soluble vitamin. Folate is an enzyme cofactor (with THF and DHF)
that is essential for regeneration. It activates vitamin B12, helps in the synthesis of DNA
and is essential for new growth. Folate is essential for pregnant women. Folate (from the
word foliage) is found in asparagus, green leafy vegetables, grains, beans, peas, oranges
and avocados. Early signs of Folate deficiency include irritability, fatigue, confusion,
headache, anemia and gastrointestinal deterioration. Folate deficiencies occur when there
is a high demand for new cell synthesis: pregnancy, cancer, burns, measles and blood
loss.

Biotin

an essential water-soluble vitamin. Biotin is necessary for proper functioning of the
energy-producing TCA Cycle. Biotin is found in soybeans, egg yolks, whole grains, fish
and organ meats. Early signs of Biotin deficiency include skin rash, depression, lethargy,
numb/tingling sensation in arms/legs, hair loss and fatigue.

Agel MIN 5

Agel MIN
Agel MIN Essential Mineral Ingredients
Calcium

an essential macromineral. Calcium, the most abundant mineral in the body, is essential
for the strength and growth of skeletal bones and teeth. Calcium contributes to muscle
contractions, blood clotting, nerve impulse transmission and hormone secretion. Calcium
is found in water, milk, milk products, tofu, broccoli, watercress & cauliflower. Early
signs of calcium deficiency include bone weakness, brittle bones, cracked teeth and
fatigue.

Phosphorus

an essential macromineral. Phosphorus, the second most abundant body mineral, is
essential for bone strength, bone growth and teeth strength. Phosphorus is part of all
energy reactions in the body, is a key component of DNA and RNA (cell growth) and is
integral in phospholipids that control protein-activation cell nutrition. Phosphorus is
found in all meat sources, beans, seeds, nuts, milk and milk products. Early signs of
phosphorus deficiency include demineralization of bones and teeth, bone weakness,
fatigue and lethargy.

Iodine

an essential mineral. Iodine is the key nutrient of the thyroid gland that regulates body
metabolism, body temperature, growth, reproduction, nerve growth and muscle function.
Iodine is found mainly from iodized table salt, sea salt, sea-grown plants (seaweed) and
animal life (seafood). Early signs of iodine deficiency include low metabolism, fatigue,
lack of initiative and eventually goiter (enlargement of thyroid gland in throat).

Magnesium

an essential macromineral. Most magnesium reserves are bound in bone and teeth.
Magnesium is a common enzyme cofactor in facilitating efficient biochemical reactions.
Magnesium is necessary for muscle contraction, blood clotting, regulating blood
pressure, metabolism of food to energy and for immune system health. Magnesium is
found in water, nuts, whole grains, green leafy vegetables, chocolate and seafood. Early
signs of magnesium deficiency are weakness, confusion, bizarre muscle movements,
difficulty swallowing and fatigue.

Zinc

an essential macromineral. Zinc is a very common metalloenzyme cofactor that is
intrinsically involved in generating energy from food. Zinc, in conjunction with calcium
and magnesium, are essential for bone growth and bone strength. Zinc also affects blood

Agel MIN 6

Agel MIN
clotting, thyroid hormone function, insulin activity, activates Vitamin A, wound healing,
fetal development and influences learning and behavior. Zinc is found in protein-rich
foods (meat, poultry and seafoods), beans, peas and whole-grains.

Selenium

an essential micromineral. Selenium is a powerful antioxidant that also part of the
enzyme glutathione peroxidase. Selenium and Vitamin E work in antioxidant synergy.
Selenium is needed for proper thyroid (metabolism) function. Selenium is found as a
trace mineral in many fruits and vegetables; as well as in meat and seafood. Signs of
selenium deficiency include fatigue and heart diseases.

Copper

an essential micromineral. Copper is a common cofactor with many enzymes
(metalloenzymes) to generate maximum energy from the food you eat. Copper is found in
beans, peas, whole grains, nuts, seafood and drinking water. Copper deficiency is rare,
but can be implicated with high blood cholesterol, genetic disorders, anemia and bone
abnormalities.

Manganese

an essential micromineral. Manganese is a common enzyme cofactor (metalloenzymes);
working with many enzymes to efficiently converts food into energy. Manganese is
typically stored in bone, liver and kidneys. Manganese is found in nuts, whole grains and
leafy vegetables.

Chromium

an essential micromineral. Chromium enhances insulin action, is involved in the
conversion of carbohydrate and fat into energy. Chromium is found in meats, nuts and
vegetable oils. Chromium deficiency can lead to diabetic-type inability to metabolize
glucose normally.

Molybdenum

an essential micromineral. Molybdenum is a cofactor for several metalloenzymes to
convert food into energy. Molybdenum is found in legumes, leafy green vegetables, milk,
whole grains and milk products.

Vanadium

a trace mineral. Vanadium is involved in normalizing blood glucose, strengthening teeth
and bones. Vanadium is found in grains, mushrooms and seafood.

Agel MIN 7

Agel MIN
Inositol

a key portion of phospholipids that make up cell membranes. Inositol allows for proper
neurotransmission, metabolic regulation and normal growth. Inositol is found in seafood
(krill).

References

1: Fairfield KM, Fletcher RH, Vitamins for Chronic Disease Prevention in Adults:
Scientific Review, JAMA, 2002
Jun 19; 287(23): p. 3116-3124.

2: Stampfer, M.J. and E.B. Rimm, Epidemiologic evidence for vitamin E in prevention of
cardiovascular disease.
Am J Clin Nutr, 1995. 62(6 Suppl): p. 1365S-1369S.

3: Rimm, E.B. and M.J. Stampfer, The role of antioxidants in preventive cardiology.
Curr Opin Cardiol, 1997. 12(2): p. 188-94.

1: Schunemann, H.J., et al., The relation of serum levels of antioxidant vitamins C and E,
retinol and carotenoids with pulmonary function in the general population.
Am J Respir Crit Care Med, 2001. 163(5): p. 1246-55.

2: McKay, D.L., et al., The effects of a multivitamin/mineral supplement on
micronutrient status, antioxidant capacity and cytokine production in healthy older adults
consuming a fortified diet.
J Am Coll Nutr, 2000. 19(5): p. 613-21.

3: Brown, B.G., et al., Simvastatin and niacin, antioxidant vitamins, or the combination
for the prevention of coronary disease.
N Engl J Med, 2001. 345(22): p. 1583-92.

4: Kushi, L.H., et al., Dietary antioxidant vitamins and death from coronary heart disease
in postmenopausal women.
N Engl J Med, 1996. 334(18): p. 1156-62.

Agel MIN 8

Agel OHM
The fast–paced environment of everyday living is stressful and at times overwhelming.
Lacking the nutrients to provide both sustained energy and that “burst of energy” often
needed, modern diets frequently require supplements to fill the gap.

Agel OHM, is a blend of vitamins, minerals, and herbs that complements a proper diet
and regular exercise to support the body by providing the “extra energy” required to meet
everyday demands. It does not rely upon chemical stimulants like caffeine or ephedra.
Rather, it looks to a B–complex vitamin–based formula that acts as a coenzyme to
facilitate the body’s own metabolic processes required to convert carbohydrates into
energy. Panax Ginseng is included, a strong antioxidant helping the body to resist
stressful influences. Panax Ginseng has also been associated with beneficial effects on
motor performance, cognitive behavior and overall Quality of Life. Likewise, OHM
contains Rhodiola rosea to help improve physical endurance and mental performance,
and to reduce stress-induced fatigue in humans. Schizandra, grown in China and Korea is
another premium herb found in OHM, used historically and today to help improve
concentration, strength, stamina, endurance, and alertness, without causing nervousness
like caffeine related stimulants.

Although nothing can replace a healthy diet and regular physical activity, Agel OHM
may be an excellent source of additional energy during a stressful day.

Agel OHM Benefits
Agel™ OHM is the Gelceutical™ designed to boost your energy when you are feeling
tired, fatigued or lazy. An added benefit of OHM is to provide focus when you are
lacking motivation or stressed by life’s circumstances. Therefore, OHM can be summed
up in 2 words: 1) energy and 2) focus.

Health Benefits
Energy Increased energy is obtained from OHM by providing key nutrients that either 1)
generate more energy from your food or 2) are direct sources of energy to the body. The
first category (helping to generate energy from food) is a collection of water–soluble B–
vitamins. B–vitamins are enzyme cofactors that generate more energy from your diet of
carbohydrates, fats and proteins. The second category (direct sources of energy) is D–
ribose. D–ribose is the quick energy the body uses for bursts of speed.

Focus There are 3 natural herbal ingredients that help provide you focus. Helping to
reduce stress, provide feelings of motivation, increase cognitive functions (memory &
learning), and enhance physical work & endurance can be wrapped up in a single word –
focus. These benefits are provided by the synergistic action of Schizandra fruit, Ginseng
root and Rhodiola root.

Agel OHM 1

Agel OHM
Who and When
Recommended for healthy adults (including older teenagers) and athletes. Consume
during the morning or afternoon (for those who sleep at night). Consume one Agel OHM
packet a day. Some individuals may want to “rip ‘n’ sip” two packets in a day when
energy levels are extremely low.

Precautions
Not recommended for children or pregnant/nursing women. Those with very high blood
pressure or high intracranial pressure should use caution. May cause sleeplessness if
consumed too soon before bedtime.

Signs of Low-Energy and Lack of Focus
• Afternoon fatigue
• Lack of daily focus
• Doing low-priority tasks first
• Tired after a full night’s sleep
• Eating too much junk food
• Easily cross or angry
• Complain about lack of energy
• Complain about others’ energy levels’
• Move around slowly
• Feel inadequate as a parent
• Have to stop between flights of stairs
• Eat enough, but do not feel energetic
• Not motivated to work
• Prefer to sit and watch TV
• No zest for life
• Feel stress from work or home
• Feel like too many tasks to do
• Feel like all tasks have equal priority
• Easily stressed by the unexpected
• Always feel overworked
• Never feel like receiving adequate rest
• Frequently sick
• Have memory lapses
• Problems focusing on learning
• Difficulty learning new concepts

These statements have not been evaluated by the Food and Drug Administration. This
product is not intended to diagnose, treat, cure or prevent any disease

Agel OHM 2

Agel OHM
Agel OHM Ingredients
Vitamin C (Ascorbic acid)
an essential water-soluble vitamin, a powerful antioxidant against free radicals, is helpful
for neurotransmitters synthesis (helping with coordination) Vitamin C helps you receive
energy by efficiently metabolizing amino acids (from protein). Vitamin C is found in
citrus, berries, fruits, & green vegetables. Early signs of deficiency are usually in elderly,
alcoholics, and infants. Vitamin C may guard against colds and help your immune
system.

Vitamin B1
an essential water-soluble B-vitamin. Thiamin is an enzyme cofactor (with TPP) for
efficient conversion of protein, carbohydrate and fat into energy. Thiamin is important for
proper functioning of nerve membranes. It is needed for the metabolism of many sugars.
Thiamin is found in whole grains, meats, greens & beans. Early signs of deficiency are
depression, muscle weakness (after only 10 days), apathy, confusion, irritability and rapid
degeneration of nervous system activity.

Vitamin B2 (Riboflavin)
an essential water-soluble B-vitamin. Riboflavin is an enzyme cofactor (with FAD and
FMN) for many energy metabolism reactions involving dietary proteins, carbohydrates
and fats. Riboflavin is found in dark, green, leafy vegetables & dairy products. Early
signs of deficiency are that minor injuries do not heal because new cells cannot replace
old cells, confusion, greasy skin, inflammation of the eyes, lips, or tongue.

Vitamin B3 (Niacin)
an essential water-soluble B-vitamin. Niacin is an enzyme cofactor (with NAD and
NADP) for rapid metabolism of protein, carbohydrate and fat to energy in every cell.
Niacin is found in dairy products, meats & whole grains. Early signs of B3 deficiency are
fatigue, decreased appetite, indigestion that can lead to diarrhea, dermatitis, dementia and
death.

Vitamin B5 (Pantothenic acid)
an essential water-soluble B-vitamin. Pantothenic acid is an enzyme cofactor (with CoA)
for energy metabolism from all food sources. Pantothenic acid is found in meats,
mushrooms, broccoli and whole grains. Early signs of deficiency include fatigue,
vomiting, nausea, stomach cramps, insomnia, depression, irritability and apathy.

Agel OHM 3

Agel OHM
Vitamin B6 (Pyridoxine)
an essential water-soluble B-vitamin. Pyridoxine is an enzyme cofactor (with PLP &
PMP) converting amino acids & fatty acids into energy. Some pyridoxine can be stored
in muscle tissue. Vitamin B6 influences immune system activity and cognitive
performance. Vitamin B6 is found in bananas, potatoes, chicken, fish, and meats. Early
signs of B6 deficiency include anemia, depression, confusion, fatigue, headaches, nerve
damage and dermatitis.

Vitamin B12 (Cobalamin)
an essential water-soluble B-vitamin. Vitamin B12 activates folate activity and is
activated by folate. Vitamin B12 helps DNA synthesis for new cells, protects nerve cells,
and promotes normal growth & bone cell activity. B12 found in meats & dairy products.
Early signs of B12 deficiency include fatigue, hypersensitivity of skin, anemia, sore
tongue & degeneration of nerves.

Chromium
an essential mineral. Chromium enhances insulin action, is involved in the conversion of
carbohydrate and fat into energy. Chromium is found in meats, nuts and vegetable oils.

Vanadium
a trace mineral. Vanadium is involved in normalizing blood glucose, strengthening teeth
and bones. Vanadium is found in grains, mushrooms and seafood.

Inositol
a key portion of phospholipids that make up cell membranes. Inositol allows for proper
neurotransmission, metabolic regulation and normal growth. Inositol is found in seafood
(krill).

Taurine
a semi-essential amino acid. Taurine is necessary for metabolism - energy production.
Taurine helps in normal functioning of heart muscle, skeletal muscle, white blood cells &
the central nervous system. Taurine is found in dairy products, meats and fish.

D-ribose
an integral part of DNA and RNA. D-ribose is “instant energy”, “liquid energy”, the
body’s own form of quick energy.

Agel OHM 4

Gel Technology Delivers Nutrients in Revolutionary New Way

Gel Technology Delivers Nutrients in Revolutionary New Way

Recomendados

Recomendados

Mais conteúdo relacionado

Destaque

Destaque (6)

Semelhante a Gel Technology Delivers Nutrients in Revolutionary New Way

Semelhante a Gel Technology Delivers Nutrients in Revolutionary New Way (20)

Gel Technology Delivers Nutrients in Revolutionary New Way